Prior authorization list for advanced imaging/radiology CPT/HCPCS codes
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Lists CPT and HCPCS procedure codes for advanced imaging, molecular genetic, and related services that may require prior authorization; notes managed-by vendor (Carelon) and addition of site-of-care to medical necessity criteria effective 01/01/2025.
Codes 95965 and 95966 (MEG services) were added effective 1/1/2026.
Multiple CT and MRI codes have 'addition of site of care to the medical necessity criteria' effective 01/01/2025.
Addition of site of care to the medical necessity criteria for multiple advanced imaging CPT codes effective 01/01/2025.
Multiple new molecular genetic test codes (0465U through 0571U and others) are listed with 'Managed By = Carelon' and many marked 'Add effective' with 2025 effective dates.
Several pharmacogenomic and transplant-related cfDNA and sequencing panels added with specified gene lists and sample types.
Coverage Criteria and Managed Code Listings
Coverage contingent on Carelon medical necessity (site-of-care added)
Covered when medical necessity criteria (including site of care) as managed by Carelon are met for the listed CPT codes.
Providers must follow Carelon prior authorization processes for these codes
Panel composition / coverage criteria
Covered when panel testing includes required gene content for the specified clinical indication
Detailed gene lists are provided inline in the policy for many panels.
Enumerated tests and contexts
Codes and their stated clinical/test contexts (no explicit coverage decision rules provided in this excerpt).
No explicit medical necessity criteria present in these chunks; utilization managed by Carelon is indicated for many codes.
Managed PLA/U codes (index)
Listing of molecular genetic tests subject to utilization management
This segment is an index of codes and management assignments only; refer to other sections for clinical coverage rules.
This document is an administrative prior authorization list of CPT and HCPCS procedure codes for which prior authorization or utilization management may be required for Blue Cross and Blue Shield of Oklahoma networks; it is not a clinical guideline. Examples of affected networks are listed in the source. Providers should consult the payer website for full medical policy details.
The excerpt does not enumerate explicit clinical exclusions. Instead, many entries are presented as a managed-code roster (each line showing a code and a "Managed By" assignment). Where present, operational updates (for example the addition of site-of-care to medical necessity criteria effective 01/01/2025) change how requests are evaluated rather than providing standalone exclusion clauses.
The listing shows individual codes annotated with status updates. For example, procedure code 92633 is documented in the file as "Retire Effective 01/01/2025," indicating it will be removed from the active managed list on that date and should not be relied on for future authorization workflows after retirement.
Many entries in the code lists include a Managed By = Carelon field. Across imaging and molecular/genetic sections, codes marked "Managed By = Carelon" indicate that Carelon is the utilization manager and the provider must follow Carelon's prior authorization and medical necessity processes for those services.
Several test codes include scheduled retirements noted in the listing. Examples in the molecular/genetic section include 0078U — Retire Effective 07/01/2025 and multiple PLA/U entries marked "Retire Effective 04/01/2025"; other codes show planned add/retirement effective dates in 2025. Providers should not order or bill retired codes after their retire date and should confirm current code status with Carelon or the payer.
Within the excerpt there are no explicit standalone exclusion conditions (e.g., lists of specific non-covered clinical scenarios). Instead, the file functions as a managed-code index: services are subject to utilization management and coverage is contingent on meeting the payer/Carelon medical necessity criteria (including updated site-of-care requirements where noted).
The entry for code 0078U (a pain-management pharmacogenomic genotyping panel) is annotated "Retire Effective 07/01/2025," which indicates that this proprietary panel will be removed from the active managed-code list on that date and may no longer be available for prior authorization or claims processing thereafter.
Several PLA/U and U-code entries in the molecular/genetic sections are annotated with retirement or effective-date notes (for example, codes shown as "Retire Effective 04/01/2025" or entries with "Add effective" dates in 2025). The file therefore includes a mix of active managed tests and codes with scheduled retire/add effective dates; review the specific code lines for exact retire/add dates.
Entries in this document are primarily presented as code listings with administrative fields (code, service category, code description, and a "Managed By" assignment). The excerpt does not contain detailed stepwise coverage logic for each entry; instead it functions as an index indicating which codes are subject to utilization management and which vendor (e.g., Carelon) manages the process.
Where a code is designated "Managed By = Carelon" the listing implies utilization management oversight by Carelon. This managed-by flag appears across advanced imaging, cardiac imaging, molecular genetic, and other service categories and signals that prior authorization and medical necessity review are processed through Carelon for those codes.
The administrative sections include device and HCPCS/HCPCS-L (L-, S-, G-, etc.) codes in addition to CPT procedure codes. Examples include hearing device HCPCS codes (e.g., L8619) and spine/musculoskeletal CPT codes (e.g., 22844–22849) that are listed for utilization management assignment.
The excerpt does not include explicit "not medically necessary" statements tied to specific clinical conditions. Rather, it documents that coverage and authorization are contingent on meeting the payer's medical necessity criteria as managed by Carelon; failure to meet those criteria (including updated site-of-care requirements) can result in denial.
No direct, standalone statements labeled "not medically necessary" are provided in the excerpt. The file instead lists codes under utilization management and notes operational updates (such as code retirements), so determinations about medical necessity must be made against the Carelon-managed criteria referenced in each code entry.
Procedure Codes and Code Tables
| 71550 | Magnetic Resonance Imaging Chest; Without Contrast |
| 71551 | Magnetic Resonance Imaging Chest; With Contrast |
| 71555 | Magnetic Resonance Angiography Chest (Excluding Myocardium) With Or Without Contrast |
| 72125 | Computed Tomography Cervical Spine; Without Contrast |
| 72126 | Computed Tomography Cervical Spine; With Contrast |
| 72127 | Computed Tomography Cervical Spine; Without Contrast Followed By Contrast |
| 72128 | Computed Tomography Thoracic Spine; Without Contrast |
| 72129 | Computed Tomography Thoracic Spine; With Contrast |
| 72130 | Computed Tomography Thoracic Spine; Without Contrast Followed By Contrast |
| 72131 | Computed Tomography Lumbar Spine; Without Contrast |
| 73700 | Computed Tomography Lower Extremity; Without Contrast |
| 73701 | Computed Tomography Lower Extremity; With Contrast |
| 73702 | Computed Tomography Lower Extremity; Without Contrast Followed By Contrast |
| 73706 | Computed Tomographic Angiography Lower Extremity With Contrast Including Noncontrast Images If Performed |
| 73718 | Magnetic Resonance Imaging Lower Extremity Other Than Joint; Without Contrast |
| 73719 | Magnetic Resonance Imaging Lower Extremity Other Than Joint; With Contrast |
| 73720 | Magnetic Resonance Imaging Lower Extremity Other Than Joint; Without Contrast Followed By Contrast |
| 73721 | Magnetic Resonance Imaging Joint Of Lower Extremity; Without Contrast |
| 73722 | Magnetic Resonance Imaging Joint Of Lower Extremity; With Contrast |
| 73723 | Magnetic Resonance Imaging Joint Of Lower Extremity; Without Contrast Followed By Contrast |
| 74150 | Computed Tomography Abdomen; Without Contrast |
| 74160 | Computed Tomography Abdomen; With Contrast |
| 74170 | Computed Tomography Abdomen; Without Contrast Followed By Contrast |
| 74174 | Computed Tomographic Angiography Abdomen And Pelvis With Contrast Including Noncontrast Images If Performed |
| 74175 | Computed Tomographic Angiography Abdomen With Contrast Including Noncontrast Images If Performed |
| 74176 | Computed Tomography Abdomen And Pelvis; Without Contrast |
| 74177 | Computed Tomography Abdomen And Pelvis; With Contrast |
| 74178 | Computed Tomography Abdomen And Pelvis; Without Contrast Followed By Contrast |
| 74261 | Computed Tomography Abdomen and Pelvis Including Image Postprocessing; Without Contrast |
| 74262 | Computed Tomographic (CT) Colonography Diagnostic Including Image Postprocessing; With Contrast |
| 74263 | Computed Tomographic (CT) Colonography Screening Including Image Postprocessing |
| 74712 | Magnetic Resonance Imaging Fetal; Single Or First Gestation |
| 74713 | Magnetic Resonance Imaging Fetal; Each Additional Gestation |
| 75635 | Computed Tomographic Angiography Abdominal Aorta And Bilateral Iliofemoral Lower Extremity Runoff With Contrast |
| 76376 | 3D Rendering With Interpretation And Reporting (concurrent) |
| 76377 | 3D Rendering Requiring Image Postprocessing On Independent Workstation |
| 76380 | Computed Tomography Limited Or Localized Follow-Up Study |
| 76390 | Magnetic Resonance Spectroscopy |
| 76391 | Magnetic Resonance Elastography |
| 77046 | Magnetic Resonance Imaging Breast Without Contrast; Unilateral |
| 77047 | Magnetic Resonance Imaging Breast Without Contrast; Bilateral |
| 77048 | Magnetic Resonance Imaging Breast Without And With Contrast; Unilateral |
| 77049 | Magnetic Resonance Imaging Breast Without And With Contrast; Bilateral |
| 78012 | Measurement(s) Including Stimulation/Suppression or Discharge |
| 78013 | Thyroid Imaging |
| 78014 | Thyroid Imaging With Uptake Quantitative Measurement |
| 78015 | Thyroid Carcinoma Metastases Imaging; Limited Area |
| 78016 | Thyroid Carcinoma Metastases Imaging; With Additional Studies |
| 78018 | Thyroid Carcinoma Metastases Imaging; Whole Body |
| 78020 | Thyroid Carcinoma Metastases Uptake |
| 78070 | Parathyroid Planar Imaging |
| 78071 | Parathyroid Planar Imaging With Tomographic (SPECT) |
| 78072 | Parathyroid Imaging With SPECT And CT for Localization |
| 0634T | CT Breast Including 3D Rendering; With Contrast |
| 0635T | CT Breast Including 3D Rendering; Without Contrast Followed By Contrast |
| 0636T | CT Breast Including 3D Rendering Bilateral; Without Contrast |
| 0637T | CT Breast Including 3D Rendering Bilateral; With Contrast |
| 0648T | Quantitative MR For Analysis Of Tissue Composition; Single Organ |
| 0649T | Quantitative MR For Analysis Of Tissue Composition Obtained With Diagnostic MRI |
| A9602 | Fluorodopa F-18 Diagnostic Per Millicurie |
| A9800 | Gallium Ga-68 Gozetotide Diagnostic (Locametz) Per Millicurie |
| C8900 | MRA With Contrast Abdomen (C-code) |
| C8901 | MRA Without Contrast Abdomen (C-code) |
| 78451 | Myocardial Perfusion Imaging SPECT Single Study At Rest Or Stress |
| 78452 | Myocardial Perfusion Imaging SPECT Multiple Studies |
| 78453 | Myocardial Perfusion Imaging Planar Single Study |
| 78454 | Myocardial Perfusion Imaging Planar Multiple Studies |
| 78459 | Myocardial PET Metabolic Evaluation Study |
| 78466 | Myocardial Imaging Infarct Avid Planar |
| 78468 | Myocardial Imaging Infarct Avid Planar With Ejection Fraction |
| 78469 | Myocardial Imaging Infarct Avid Tomographic (SPECT) |
| 93306 | Transthoracic Echocardiography With Spectral And Color Doppler; Complete |
| 93307 | Transthoracic Echocardiography Without Spectral/Color Doppler |
| 93308 | Transthoracic Echocardiography (study variant) |
| 93312 | Transesophageal Echocardiography With Probe Placement, Image Acquisition, Interpretation |
| 93314 | Transesophageal Echocardiography Image Acquisition Only |
| 93315 | Transesophageal Echocardiography For Congenital Cardiac Anomalies |
| 93320 | Doppler Echocardiography Pulsed/Continuous Wave Complete |
| 93321 | Doppler Echocardiography Follow-Up Or Limited Study |
| 93325 | Doppler Echocardiography Color Flow Velocity Mapping |
| 93350 | Stress Echocardiography |
| S8037 | MR Cholangiopancreatography (MRCP) |
| G0235 | PET Imaging Any Site Not Otherwise Specified |
| G0252 | PET Imaging for Initial Diagnosis of Breast Cancer (limited indication) |
| S8037 | Magnetic Resonance Cholangiopancreatography |
| A9602 | Fluorodopa F-18 per mCi |
| A9800 | Gallium Ga-68 Gozetotide per mCi |
| S3865 | Comprehensive Gene Sequence Analysis For Hypertrophic Cardiomyopathy (listed here as related service) |
| L8614 | Cochlear Device Includes All Internal And External Components |
| L8615 | Headset/Headpiece For Use With Cochlear Implant Device |
| L8616 | Microphone For Use With Cochlear Implant Device |
| L8617 | Transmitting Coil For Use With Cochlear Implant |
| L8618 | Transmitter Cable For Cochlear Implant |
| L8619 | Cochlear Implant External Speech Processor Replacement |
| S5501 | Home infusion therapy, catheter care maintenance, complex, per diem |
| S5502 | Home infusion therapy, implanted access device maintenance, per diem |
| S9208 | Home management of preterm labor, per diem |
| S9209 | Home management of PPROM, per diem |
| S9211 | Home management of gestational hypertension, per diem |
| S9212 | Home management of postpartum hypertension, per diem |
| S9213 | Home management of preeclampsia, per diem |
| S9325 | Home infusion therapy, pain management infusion, per diem |
| S9357 | Home infusion therapy, enzyme replacement IV therapy, per diem |
| S9359 | Home infusion therapy, anti-TNF IV therapy, per diem |
| S9372 | Home therapy; intermittent anticoagulant injection, per diem |
| S9373 | Home infusion therapy, hydration therapy, per diem |
| 81212 | BRCA1 full sequence and selected variants example code listed in series |
| 81215 | BRCA1 known familial variant |
| 81216 | BRCA2 sequence analysis (example) |
| 81471 | X-Linked Intellectual Disability Duplication/Deletion Gene Analysis (>=60 genes) |
| 81479 | Unlisted Molecular Pathology Procedure |
| 81493 | Coronary Artery Disease mRNA Gene Expression Profiling (23 genes) |
| 81504 | Tissue of origin microarray gene expression profiling of 2000 genes |
| 81520 | Oncology (Breast) mRNA gene expression profiling hybrid capture of 58 genes |
| 81430 | Hearing loss genomic sequence panel; must include sequencing of at least 60 genes |
| 81431 | Hearing loss duplication/deletion analysis including STRC/DFNB1 |
| 81432 | Hereditary breast cancer-related disorders panel; must include at least 10 genes including BRCA1/2 |
| 81433 | Hereditary breast cancer-related duplication/deletion analysis |
| 81437 | Related gene panel example entry |
| 81438 | Hereditary neuroendocrine tumor disorders duplication/deletion (retired 04/01/2025) |
| OO01U | Red Blood Cell Antigen Typing DNA - 35 antigens |
| OO06M | Oncology hepatic mRNA expression levels of 161 genes |
| 0011M | Oncology prostate mRNA expression assay of 12 genes |
| 0012M | Oncology urothelial mRNA profiling 5 genes |
| 0013M | Oncology urothelial mRNA profiling for recurrence |
| 0566U | Differentially methylated regions assay (specified DMRs) pleural fluid |
| 0567U | Whole-genome sequence analysis combining short and long reads for rare diseases |
| 0569U | ctDNA tumor methylation markers (>20000 DMRs) in whole blood |
| 0571U | Oncology DNA 80 genes + RNA 10 genes plasma clinically actionable variants |
| 20930 | Allograft morselized for spine surgery |
| 20931 | Allograft structural for spine surgery |
| 20932 | Placement and internal fixation of osteoarticular allograft |
| 20933 | Allograft hemicortical intercalary partial |
| 20934 | Allograft intercalary complete |
| 20936 | Autograft for spine surgery; local |
| 20937 | Autograft morselized |
| 20938 | Autograft structural bicortical |
| 22220 | Osteotomy of spine anterior approach single vertebral segment; cervical |
| 22590 | Arthrodesis posterior technique craniocervical (Occiput-C2) |
| 22600 | Arthrodesis posterior or posterolateral technique single interspace; cervical |
| 22610 | Arthrodesis posterior or posterolateral technique single interspace; thoracic |
| 22612 | Arthrodesis posterior or posterolateral technique single interspace; lumbar |
| 27335 | Arthrotomy With Synovectomy Knee; Anterior And Posterior |
| 27345 | Excision Of Synovial Cyst Of Popliteal Space (Baker's Cyst) |
| 27403 | Arthrotomy With Meniscus Repair Knee |
| 27405 | Repair Primary Torn Ligament Knee; Collateral |
| 27407 | Repair Primary Torn Ligament Knee; Cruciate |
| 27446 | Arthroplasty Knee Condyle And Plateau; Medial Or Lateral |
| 27447 | Arthroplasty Knee; Total Knee Arthroplasty |
What Providers Must Do / Authorization Workflow
Utilization management assignment (prior authorization management)
Prior authorization and utilization management (UM) responsibilities: Many of the codes listed in this segment are managed by Carelon for prior authorization and utilization management. Providers must follow the Carelon UM/prior authorization process where the code entry indicates "Managed By = Carelon." A subset of codes (notably some home infusion and S-code entries) are managed directly by BCBSOK — follow the Managed By field for routing each request.
- Follow Carelon's prior authorization/UM process for codes marked "Managed By = Carelon" (examples throughout Advanced Imaging/Radiology and Molecular Genetic Lab Testing lists).
- For codes marked "Managed By = BCBSOK", follow BCBSOK UM/prior authorization instructions (examples: home infusion per-diem S-codes where indicated).
- Document site-of-care where the code's Updates note requires it (e.g., multiple Advanced Imaging entries effective 01/01/2025).
Denial risk from unmet updated medical necessity/site-of-care criteria
Denial risk if updated medical necessity or site-of-care criteria are not met: several Advanced Imaging/Radiology codes include an "Updates = Effective 01/01/2025, addition of site of care to the medical necessity criteria" note. Failure to meet the updated medical necessity or site-of-care criteria (and/or to obtain required prior authorization) may result in claim denial or retrospective noncoverage.
- Document site-of-care and meet updated medical necessity criteria for codes with an "addition of site of care" update.
- Obtain prior authorization from the designated manager (Carelon or BCBSOK) when required to avoid denial.
Not specified in this segment; no explicit additional actions
No explicit additional provider actions specified in this segment beyond following the Managed By routing, documenting site-of-care when required, and obtaining prior authorization where noted.
- This segment does not specify separate documentation templates or clinical forms — follow the UM vendor's documentation guidance.
- No step therapy rules are present for services in this excerpt.
Code usage conflicts
Code usage conflicts and billing notes: some entries warn about mutually exclusive usage or coding conflicts (example: home infusion per-hour S9810 should not be used with per-diem home infusion codes). Inconsistent coding may trigger utilization management review or denial.
Utilization management oversight (managed by Carelon)
Utilization management oversight: molecular genetic CPT/HCPCS codes, cardiac imaging, advanced imaging/radiology, musculoskeletal/spine surgery codes and others in this segment may be subject to utilization management by Carelon. Where a code is managed by Carelon, prior authorization requests and clinical documentation reviews are routed to Carelon.
- Follow the Carelon UM/prior authorization workflow for codes marked "Managed By = Carelon."
- Claims for codes managed by Carelon may require the Carelon prior authorization number on claim submission.
Specific codes are marked as 'Retire Effective' and other date updates
Retirement / effective-dates: specific molecular genetics codes in this segment include retirement or effective-date updates. Providers should note retirements and effective dates when ordering, billing, or requesting authorization.
- 0078U — Retire Effective 07/01/2025 (managed by Carelon).
- 81433 and 81436 — Retire Effective 04/01/2025 (managed by Carelon).
- Check each code's "Updates" field for effective dates and retirements before submission.
Prior authorization noted
Prior authorization noted: some codes have an explicit prior authorization requirement or a note that prior authorization is required through the listed manager.
- CPT 27412 (Autologous Chondrocyte Implantation Knee) — Prior Authorization required through Carelon.
- Other codes may include "Prior Authorization required" in their Updates — follow the individual code entry.
Billing/documentation note
Documentation and billing notes: this segment includes code descriptions that often reference specimen/test details or panel composition. Clinical test description should appear on the claim and panels must include required genes/sequencing where specified.
- Include clinical test description and specimen/test details on the claim as applicable.
- For panel codes, ensure the panel includes the minimum gene set specified in the code description and document that on referral/authorization materials.
Claims and management vendor — follow Managed By field
Claims and management vendor: submit prior authorization requests and claims per the manager identified in each code's entry. Failure to follow the designated UM/prior authorization process may lead to claim denial or delays.
- Submit prior authorization requests to Carelon for codes marked "Managed By = Carelon."
- For BCBSOK-managed codes, follow BCBSOK prior authorization submission instructions.
- Reference the CPT/HCPCS code and authorization number on claims.
No step therapy rules provided in this excerpt
No step therapy rules provided: this excerpt contains no step therapy rules for the listed services.
- If step therapy requirements are needed for a service, consult the full policy or UM vendor guidance — none are present in this segment.
Covered Indications and Medical Necessity Scope
Prior authorization applicability (no clinical indications provided in this portion)
Failure to obtain required prior authorization may trigger claim denial.
Various indications covered under Carelon-managed medical necessity criteria
Providers must submit clinical rationale and site-of-care information to Carelon as part of prior authorization requests.
No clinical indication criteria included in this segment; only procedure listings and management assignments are present
No clinical indication criteria included in this segment; only procedure listings and management assignments are present.
Refer to Carelon for specific clinical criteria and prior authorization rules.
Contrast / Study Variant Notes
Not Covered Items / Exclusions
The document identifies G0219 (PET imaging whole body; melanoma) in the not-covered context within the excerpt, noting this code is associated with whole-body PET imaging for melanoma under non-covered indications. Providers should confirm clinical appropriateness and payer coverage rules before ordering.
Background and Scope
Background: this file is an administrative utilization management roster that identifies advanced imaging and related CPT/HCPCS codes that may require prior authorization for BCBSOK networks. It is intended to direct providers to the appropriate utilization manager (for many codes, Carelon) and to note operational updates (code additions, retirements, and the effective inclusion of site-of-care in medical necessity criteria). Clinical medical policy details remain available on the BCBSOK Medical Policy Website.
Definitions and Key Terms
Policy Updates
MEG procedure codes 95965 and 95966 were added and are designated as managed by Carelon (add effective 01/01/2026).
Multiple molecular genetic PLA/U codes (e.g., 0554U) were added with an effective date of 10/01/2025 and are managed by Carelon for utilization management.
Several molecular genetic U-codes (e.g., 0478U, 0481U, 0485U, 0486U) were added with effective dates in 07/01/2025 and listed as managed by Carelon.
Addition of site-of-care to medical necessity criteria for numerous advanced imaging CT/MR/CTA/MRA codes (examples include 70450, 70460, 70470, 70492, 70496, 70498, 70540, and many extremity, spine, abdomen/pelvis CT/MR codes) effective 01/01/2025; these codes are managed by Carelon for utilization management.
Multiple molecular genetic and advanced imaging CPT/HCPCS codes were recorded as 'Managed By = Carelon' indicating Carelon is the utilization manager beginning with listed 2025 updates.
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