HCPCS Level II code S9494 denotes per-diem administrative and professional pharmacy services for home infusion antibiotic, antiviral, or antifungal therapy. It covers care coordination, pharmacy oversight, and necessary supplies and equipment while drugs and nursing visits are billed separately. Nationally, this code is important as home infusion expands as an alternative to inpatient care, affecting pharmacy management, care coordination workflows, and payer reimbursement models for outpatient antimicrobial therapy.

Key payers in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of the code’s clinical and service context, guidance on typical site-of-service use, common modifier practices (listed separately), and what to expect when billing this per-diem administrative code alongside separate drug and nursing charge lines. The publication also summarizes benchmarks and payer coverage considerations, and highlights policy and billing cautions relevant to home infusion programs.

This summary is intended for national audiences — clinicians, home infusion pharmacists, revenue cycle staff, and policy analysts — seeking clear, practical context about when and how S9494 is used and its role within home-based antimicrobial therapy.