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    v1.0.28
    OpenPayerBilling CodesOther Diagnostic Radiology (Diagnostic Imaging) Related ProceduresCPT cpt-76391-magnetic-resonance-elastography-liver-stiffness-assessment
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    CPT 76391: Magnetic Resonance Elastography for Tissue Stiffness

    Medicare pays $137 on average nationally for this procedure.

    CPT code 76391 describes magnetic resonance elastography (MRE), where a vibration source is placed over suspicious tissue or an organ (commonly the liver) to induce tissue vibration while magnetic resonance imaging assesses tissue elasticity or stiffness; this is an imaging service typically performed in an outpatient or hospital radiology department using MR equipment to evaluate focal or diffuse tissue stiffness for diagnostic characterization.

    For related coverage guidance, see recent payer policy updates: Fixed Wing Air Ambulance Transport, Air Ambulance, Ambulance Services (for New Mexico Only).

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 55-year-old with chronic liver disease and elevated liver enzymes or a focal hepatic lesion detected on ultrasound. The ordering hepatologist or radiologist requests elastography using magnetic resonance imaging to noninvasively assess liver stiffness to help stage fibrosis or characterize a suspicious lesion. The patient arrives to the outpatient radiology MRI suite, screening for MRI safety and contraindications, changes into gown, and is positioned supine. A vibration transducer (external driver) is placed over the right upper quadrant (liver) and synchronized with the MRI sequence. The MRI technologist performs the specialized MR elastography sequence while the driver generates low-frequency vibrations; images are obtained to produce elastograms that quantify tissue stiffness. The radiologist reviews the elastography images alongside conventional liver MRI sequences, reports liver stiffness measurements (often in kilopascals) and maps, and integrates findings with clinical history to inform staging of fibrosis or evaluation of focal hepatic lesions. Typical site of service is an outpatient or hospital-based MRI suite within radiology or an imaging center. Typical service type is diagnostic MR elastography of an abdominal organ (commonly the liver). Typical modifiers appended depend on payer and reporting needs, such as professional component or technical component when services are split between facility and interpreting physician.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    74183Magnetic resonance imaging, abdomen; with contrast material(s)Often performed in the same session to evaluate liver lesions alongside MR elastography for characterization.
    74182Magnetic resonance imaging, abdomen; without contrast material(s)Performed when elastography is done without contrast or as complementary noncontrast anatomical imaging.
    76498Unlisted diagnostic radiology procedure (specify)Used rarely when a specialized or proprietary elastography acquisition lacks a specific CPT; most MR elastography uses 76391.
    76942Ultrasonic guidance for aspiration and/or biopsyMay be performed in the workflow if elastography identifies a focal lesion that requires tissue sampling.
    76930Ultrasonic guidance for percutaneous radiological proceduresMay be used when image-guided intervention follows elastography findings.

    Related Modifiers

    9 rows

    ModifierDescriptionWhen to Use
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    76Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
    77Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
    59Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Related Provider Taxonomies

    8 rows

    Taxonomy CodeSpecialtyNotes
    208M00000XHospitalist PhysicianHospitalists are physicians whose primary professional focus is the general medical care of hospitalized patients. Their activities include patient ca…
    207RC0000XCardiovascular Disease PhysicianAn internist who specializes in diseases of the heart and blood vessels and manages complex cardiac conditions such as heart attacks and life-threaten…
    207K00000XAllergy & Immunology PhysicianAn allergist-immunologist is trained in evaluation, physical and laboratory diagnosis, and management of disorders involving the immune system. Select…
    207L00000XAnesthesiology PhysicianAn anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
    103TA0400XAddiction (Substance Use Disorder) PsychologistA psychologist with a proficiency that involves the application of psychological treatment of addiction stemming from the use of alcohol and other psy…
    405300000XPrevention ProfessionalPrevention Professionals work in programs aimed to address specific patient needs, such as suicide prevention, violence prevention, alcohol avoidance,…
    2080B0002XPediatric Obesity Medicine PhysicianA physician who specializes in the treatment of obesity demonstrates competency in and a thorough understanding of the treatment of obesity and the ge…
    111NR0200XRadiology ChiropractorChiropractic radiology is a referral specialty that provides consultation services at the request of other qualified doctors. Chiropractic radiologist…

    Related ICD-10-CM Codes

    25 rows

    ICD-10-CM CodeDescription
    C22.9Malignant neoplasm of liver, not specified as primary or secondary
    C78.4Secondary malignant neoplasm of small intestine
    C78.7Secondary malignant neoplasm of liver and intrahepatic bile duct
    E78.5Hyperlipidemia, unspecified
    I82.401Acute embolism and thrombosis of unspecified deep veins of right lower extremity
    I82.499Acute embolism and thrombosis of other specified deep vein of unspecified lower extremity
    I85.00Esophageal varices without bleeding
    I86.4Gastric varices
    K74.60Unspecified cirrhosis of liver
    K74.69Other cirrhosis of liver

    Showing 1–10 of 25

    Related Payer Policy Updates

    Specialty: Emergency & Medical Transportation1 / 3

    10 rows

    PolicyPayerEffective Date
    Fixed Wing Air Ambulance TransportCigna2026-08-15
    Air AmbulanceAmbetter Georgia2026-08-01
    Ambulance Services (for New Mexico Only)UnitedHealthcare2026-08-01
    Ambulance Services (for Tennessee Only)UnitedHealthcare2026-08-01
    Clinical Policy: Air AmbulanceArizona Complete Health2026-08-01
    Air AmbulanceCentene2026-08-01
    Clinical Policy: Air AmbulanceCentene2026-08-01
    Clinical Policy: Air AmbulanceAmbetter Nevada2026-08-01
    Ambulance TransportProvidence Health Plan2026-07-01
    Air ambulance transport coverage criteriaeocco2026-07-01

    Related Codes

    CPT-76000-FLUOROSCOPY-UP-TO-ONE-HOUR-REAL-TIME-IMAGING

    CPT 76000: Fluoroscopy, up to 1 hour, real-time imaging

    CPT-76010-PEDIATRIC-GI-FOREIGN-BODY-SINGLE-IMAGE

    CPT 76010: Single-View Pediatric GI Radiograph for Foreign Body Detection

    CPT-76017-MR-SAFETY-MEDICAL-PHYSICS-EVALUATION-IMPLANTS

    CPT 76017: MR Safety Assessment by Medical Physicist

    CPT-76018-MR-DEVICE-PROGRAMMING-AND-PREPARATION

    CPT 76018: MR-Day Implant Programming and Supervision

    CPT-76019-MR-IMPLANT-POSITIONING-AND-SAFETY-SUPERVISION

    CPT 76019: MR Implant Positioning and Safety Supervision

    CPT-76080-ABSCESS-FISTULA-SINUS-TRACT-IMAGING-INTERPRETATION

    CPT 76080: Supervision & Interpretation of Abscess/Fistula/Sinus Tract Imaging

    CPT-76098-INTRAOPERATIVE-SPECIMEN-IMAGING

    CPT 76098: Specimen Radiography After Excision

    CPT-76100-SINGLE-PLANE-TOMOGRAPHIC-RADIOGRAPHY

    CPT 76100: Single-Plane Motion X‑ray Scanning

    CPT-76120-MOTION-XRAY-RECORDING-DYNAMIC-RADIOGRAPHY

    CPT 76120: Motion X‑ray Recording of a Cycle of Movement

    CPT-76125-MOTION-RADIOGRAPHY-CYCLE-MOVEMENT

    CPT 76125: Motion X‑ray (Cine) Imaging of a Cycle of Movement

    Showing 1–10 of 20

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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