CPT code 76391 defines magnetic resonance elastography (MRE), a diagnostic imaging technique that uses an external vibration source and magnetic resonance imaging to assess tissue elasticity and stiffness. MRE is most commonly applied to organs such as the liver to help identify fibrosis, cirrhosis, and other conditions that alter tissue stiffness. Nationally, MRE has clinical significance as a noninvasive alternative to biopsy for evaluating organ stiffness and staging liver disease.

Key payers included in this analysis are Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of clinical context for CPT code 76391, typical sites of service, and the scope of services represented by the code. The publication summarizes payer coverage patterns, common billing considerations, and how MRE fits into diagnostic imaging workflows. It also highlights benchmarks and policy updates where available and notes areas where input data is not available.

This summary is written for a national audience and is intended to inform health plan analysts, practice managers, and imaging leaders about the clinical role and billing characterization of CPT code 76391 within current diagnostic imaging services.