Procedures and services considered always investigational or cosmetic
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List of specific procedures, services, and billing codes designated by Eocco/Moda Health Commercial as always investigational or cosmetic for Moda Health Commercial Group and Individual Members. Applies to coverage determinations and claims processing for the listed services.
No material clinical or coverage changes in this revision.
Coverage stance and listed Always Investigational / Always Cosmetic items
Not Medically Necessary / Cosmetic — Listed Items
Not covered when designated Always Investigational or Always Cosmetic in the list
Applies to the specific codes and service descriptions as listed in the document.
Always Investigational / Cosmetic
Not covered — Always investigational or cosmetic
See code groups for listed items
Always Investigational / Not Covered
Not covered (Always Investigational) — services and codes listed below are designated Always Investigational.
Applies to the codes enumerated in the coding module and corresponding chunks.
Always Investigational / Not Covered
Not covered services (listed as Always Investigational)
See individual code entries in coding module for specifics.
Always Investigational / Not Medically Necessary
Not covered — Always Investigational
No conditional coverage criteria provided in these chunks; items are listed for exclusion.
Not covered when designated Always Investigational
Stance for listed procedures in these chunks
These codes are identified as investigational across multiple entries in the document.
Always Investigational / Always Cosmetic (Not Covered)
Not covered when listed codes apply
This segment is a code list; no exceptions or medical-necessity criteria provided in this window.
Some HCPCS product entries in the list are explicitly designated Always Cosmetic. For example, the entry for J0591 (injection, deoxycholic acid) is annotated with an exceptions note indicating Always Cosmetic, and several product Q-codes for topical/implantable biologic wound/amnion products are listed with cosmetic or investigational designations in the same segment.
The document identifies multiple specific procedure and temporary codes with the annotation Always Investigational. Examples include diaphragmatic stimulation system procedure codes such as 0676T and 0678T, and numerous proprietary laboratory and U-code tests listed elsewhere in the policy; each of these is called out as Always Investigational in the code listings.
Infrared heating pad systems and related supply entries are listed as not covered in this policy segment. Specifically, HCPCS/device entries for infrared heating systems such as A4639 and E0221 are shown as Not covered, and replacement pads (eg, Q4296) are listed with an Always Investigational exception note.
Additional examples of services annotated Always Investigational include certain procedural and therapeutic codes such as 92972 (percutaneous transluminal coronary lithotripsy) and 97037 (low-level laser therapy), as well as multiple temporary and T-category entries shown in the list.
A broad set of services and codes are explicitly designated Always Investigational and therefore excluded from coverage. Representative examples include device/implant codes (periurethral adjustable balloon device codes 53451–53453), therapeutic drug monitoring panels (large-panel LC-MS/MS entries such as 0519U), and digital mental health/device management codes shown as investigational (G0553–G0554).
Items listed with the designation Always Investigational are treated as not covered under this policy. The policy explicitly shows endoscopy CPT examples such as 43290 and 43291 (deployment and removal of intragastric bariatric balloons) marked Always Investigational.
Selective enzymatic debridement procedures are listed and annotated Always Investigational. The entries include billing by area (eg, first 100 sq cm and each additional 100 sq cm) for selective enzymatic debridement of partial‑ or full‑thickness burn eschar, and these are designated investigational in the listing.
The policy lists multiple examples of electronic analysis, remote monitoring, and device-based monitoring services as investigational. Examples include digital mental health treatment management entries (G0553–G0554), implanted interstitial glucose sensor insertion/removal (G0553, G0564), and electronic analysis/programming entries for implanted sub‑scalp continuous bilateral EEG monitoring described in the code listings; these items are annotated Always Investigational.
The list classifies a wide range of services, supplies, and laboratory tests as Always Investigational or Always Cosmetic. These include many wound matrices and biologic graft product codes (A- and Q‑series), numerous proprietary laboratory U‑codes and algorithmic tests, and device/implant procedure codes — all shown with investigational or cosmetic exception notes in the code tables.
Within these code segments there are no additional conditional coverage criteria; repeated ExceptionsNotes = Always Investigational entries are used to mark listed codes. The policy does not provide alternate coverage pathways for codes labeled investigational in these chunks.
Numerous aesthetic and dermatologic procedure codes are explicitly labeled Always Cosmetic and therefore excluded from coverage. Representative examples include dermabrasion codes (15781–15783), chemical peel codes (15788–15793), and blepharoplasty/rhytidectomy entries (15820–15826), all noted as Always Cosmetic in the listings.
Many device and novel-procedure codes are flagged Always Investigational. Examples include implantable device programming and interrogation codes, transcatheter valve implant/replacement entries, novel sensor implantation and monitoring codes, and organ perfusion/EVLP device-related codes — each listed with investigational exception notes in the policy.
The policy shows specific codes labeled Always Non-covered or Always Cosmetic for certain diagnostic or supply items. For example, paternity blood typing codes 86910 and 86911 are annotated as Always Non-covered, and injectable aesthetic filler Q2026 (radiesse) is listed as Always Cosmetic.
Large groups of Q‑code products and related wound matrix/amniotic membrane items are designated Always Investigational. The document lists many such Q‑codes (for example Q4169–Q4226 and numerous sequential Q‑code entries) with exception notes marking them investigational and therefore not covered.
This section of the code list includes many temporary CPT, HCPCS, and proprietary procedure entries that are uniformly designated Always Investigational. Examples span VR procedural dissociation services, algorithmic assistive analyses, digital rehabilitation/remote therapy codes, and many Category III/T‑codes; all items shown with the investigational designation are excluded from coverage per the listing.
The policy lists specific procedural examples described as Always Investigational, such as repair using low‑energy radiofrequency for nasal valve collapse and certain oncology spheroid cell culture assays; many temporary and procedure codes shown in these chunks carry an investigational exception note.
Multiple procedures and algorithmic/neuromodulation items are listed as investigational. These include augmentative algorithmic cardiac analyses (eg, noninvasive arrhythmia simulation/assistive analyses), extracorporeal normothermic organ perfusion connections, and neuromodulation-related programming or implantation codes — each shown as Always Investigational in the code listings.
Amniotic membrane allograft product codes and digitization-of‑pathology slide codes are specifically identified as Always Investigational. The policy enumerates multiple Q‑codes for amniotic membrane products (for example Q4314–Q4326 and many subsequent Q entries) and multiple T‑codes for whole‑slide digitization and pathology digitization, all marked investigational in the listings.
Representative examples of investigational device or implant procedures include the periurethral adjustable balloon continence device insertion/removal codes (53451–53453) and implantable cardiac contractility modulation system-related codes; the policy marks these services Always Investigational and not medically necessary.
The policy consistently labels the listed services as investigational and not medically necessary. Multiple chunks reiterate that codes annotated Always Investigational or Always Cosmetic are excluded from coverage and subject to denial when billed for Moda Health Commercial members.
Remote monitoring and novel diagnostic/therapeutic monitoring services are listed as investigational. Examples include remote therapeutic monitoring entries (98986, 99445) and other remote physiologic/therapeutic monitoring device‑supply and transmission services shown with an Always Investigational exception note.
The code 15877 is explicitly flagged as Always Cosmetic in the code listings, demonstrating how specific procedural CPT codes for aesthetic procedures are annotated as non‑covered cosmetic services.
Across multiple chunks the policy provides numerous specific procedural examples that are labeled Always Investigational or Always Cosmetic, including algorithmic imaging/analysis services, novel procedural T‑codes, wound matrix product Q‑codes, and device/implant codes. Each listed code carries the exception note indicating investigational or cosmetic status and is not considered medically necessary.
Services marked Always Investigational or Always Cosmetic are treated as not medically necessary and therefore not covered. The policy repeatedly states that items in these lists (including temporary CPT/T codes, U/Q product codes, and selected CPT/HCPCS codes) are excluded from coverage based on their exception notes.
The injectable cosmetic entry Q2026 (radiesse) is shown with an Always Cosmetic exception note in the policy, indicating this specific injectable filler product is considered cosmetic and not medically necessary for coverage purposes.
Where an entry includes an ExceptionsNotes = Always Investigational label, that designation indicates the service is considered investigational and not covered; the policy reiterates that coded services with that exception note are excluded from payment under the listed member product(s).
Code lists and coding details
| A2035 | Corplex p or theracor p or allacor p, per milligram |
| C8004 | Bronchoscopy non-thermal transbronchial ablation by pulsed electric field, with CT acquisition and 3D rendering |
| C8005 | Endobronchial ultrasound guided procedures, therapeutic (listed as Always Investigational) |
| E0201 | Wheelchair transportation securement system |
| E1022 | Wheelchair transportation securement system, any type includes all components and accessories |
| E1023 | Wheelchair transit securement system, includes all components and accessories |
| E1032 | Wheelchair accessory, manual swingaway, retractable or removable mounting hardware used with joystick or other drive control interface |
| E1033 | Wheelchair accessory, manual swingaway, retractable or removable mounting hardware for headrest, cushioned, any type |
| E1034 | Wheelchair accessory, manual swingaway, retractable or removable mounting hardware for lateral trunk or hip support, any type |
| E1832 | Static progressive stretch finger device |
| 0672T | Thermal destruction of intraosseous basivertebral nerve, including all imaging guidance; first 2 vertebral bodies, lumbar or sacral |
| 64628 | Thermal destruction of intraosseous basivertebral nerve; each additional vertebral body |
| 64629 | Insertion of drug-eluting implant, including punctal dilation when performed, into lacrimal canaliculus, each |
| 68841 | Trabecular bone score (TBS), structural condition of the bone microarchitecture; calculation with interpretation and report |
| 77089 | Trabecular bone score (TBS) technical preparation and transmission of data for analysis |
| 77090 | Trabecular bone score (TBS) technical calculation only |
| 77091 | Trabecular bone score (TBS) interpretation and report on fracture-risk only by other qualified health care professional |
| 77092 | Ablation, benign thyroid nodule(s), percutaneous, laser, including imaging guidance |
| 0597T | Optical coherence tomography (OCT) of retina, remote, patient-initiated image capture and transmission |
| 0596T | Glomerular filtration rate (GFR) monitoring, transdermal, including sensor placement and administration of more than one dose of fluorescent |
| 0602T | Ablation, irreversible electroporation; 1 or more tumors per organ, including imaging guidance, percutaneous |
| 0605T | Glomerular filtration rate (GFR) measurement(s), transdermal, including sensor placement and administration of a single dose of fluorescent |
| 0632T | Percutaneous transcatheter ultrasound ablation of nerves innervating the pulmonary arteries, including right heart catheterization and angiography |
| 0686T | Treatment of amblyopia using an online digital program; device supply, educational set-up, and initial session |
| 0700T | Molecular fluorescent imaging of suspicious nevus; each additional lesion |
| 0676T | Laparoscopic repositioning of diaphragmatic lead(s), permanent implantable synchronized diaphragmatic stimulation system; first repositioned lead |
| 0678T | Laparoscopic removal of diaphragmatic lead(s), permanent implantable synchronized diaphragmatic stimulation system |
| 0679T | Insertion or replacement of pulse generator only, permanent implantable synchronized diaphragmatic stimulation system, with connection to existing lead(s) |
| 0680T | Relocation of pulse generator only, permanent implantable synchronized diaphragmatic stimulation system, with connection to existing dual leads |
| 0681T | Removal of pulse generator only, permanent implantable synchronized diaphragmatic stimulation system |
| 0682T | Programming device evaluation (in-person) with iterative adjustment of the implantable synchronized diaphragmatic stimulation system |
| 0683T | Peri-procedural device evaluation (in-person) and programming of device system parameters before or after a surgery, procedure, or test |
| 0686T | Treatment of amblyopia using an online digital program; device supply, educational set-up, and initial session |
| 0687T | Treatment of amblyopia using an online digital program; assessment of patient performance and program data by physician, with report, per calendar month |
| 0701T | Remote treatment of amblyopia using an eye tracking device; device supply with initial set-up and patient education |
| 0705T | Remote treatment of amblyopia using an eye tracking device; interpretation and report by physician, per calendar month |
| 0688T | Quantitative ultrasound tissue characterization (non-elastographic), including interpretation and report, obtained without diagnostic ultrasound examination of the same anatomy |
| 0689T | Quantitative ultrasound tissue characterization (non-elastographic), including interpretation and report, obtained with diagnostic ultrasound examination of the same anatomy |
| 0700T | Molecular fluorescent imaging of suspicious nevus; first lesion |
| 0733T | Remote body and limb kinematic measurement-based neurorehabilitative therapy; supply and technical support, per 30 |
| 0734T | Remote body and limb kinematic measurement-based therapy; treatment |
| 0752T | Digitization of glass microscope slides for level IV, surgical pathology, gross and microscopic examination |
| 0751T | Digitization of glass microscope slides for level III, surgical pathology, gross and microscopic examination |
| 0776T | concussion assessment tool 5 [SCAT5], 30 minutes of treatment |
| 0778T | Surface mechanomyography (sMMG) with IMU sensors; Always Investigational |
| Virtual reality procedural dissociation (unlisted time-based entries) | VR procedural dissociation services — initial and additional 15-minute entries (time-based); listed as investigational/not specified |
| T2051 | Kerecis omega3 marigen shield, per square centimeter |
| A2019 | Ac5 advanced wound system (ac5) |
| A2020 | Biodesign Fistula Plug |
| C1763 | Removal of esophageal sphincter augmentation device |
| Q4279 | Dermabind dl, per square centimeter; Always Investigational |
| Q4292 | Lamellas, per square centimeter; Always Investigational |
| Q4296 | Replacement pad for infrared heating pad system, each; Always Investigational |
| A4639 | Infrared heating pad system; Not covered |
| E0221 | Infrared heating pad system; Not covered |
| 0811T | Remote multi-day complex uroflowmetry equipment set-up and patient education; Always Investigational |
| 0812T | Device supply with automated report generation; Always Investigational |
| 0814T | Continuous in-person monitoring during psychedelic medication therapy; Always Investigational |
| 0820T | Continuous in-person monitoring/intervention during psychedelic medication therapy; Always Investigational |
| 0821T | Second physician concurrent during psychedelic medication therapy; Always Investigational |
| 0822T | Clinical staff concurrent during psychedelic medication therapy; Always Investigational |
| 0827T | Digitization of glass microscope slides, simple filter method; Always Investigational |
| 0828T | Digitization of slides concentration technique; Always Investigational |
| 0829T | Oncology (prostate) gene expression profile by RT-PCR of 3 genes; Always Investigational |
| 0005U | Oncology (prostate) gene expression profile by RT-PCR of 3 genes (ERG, PCA3, SPDEF), urine; Always Investigational |
| 0896T | Noninvasive augmentative arrhythmia analysis derived from computational cardiac arrhythmia simulations |
| 0898T | Noninvasive determination of absolute quantitation of myocardial blood flow (AQMBF) from CMR; Always Investigational |
| 0899T | Noninvasive estimate of AQMBF derived from assistive algorithmic analysis of CMR dataset; Always Investigational |
| 0893T | Cannulation of liver allograft prep for normothermic perfusion device; Always Investigational |
| 0894T | Connection of liver allograft to normothermic machine perfusion device; Always Investigational |
| 0896T | Connection of liver allograft to normothermic machine perfusion device, hemostasis control; each additional hour, including physiological and laboratory assessments |
| 0897T | Noninvasive prostate cancer estimation map, derived from augmentative analysis of image-guided fusion biopsy and pathology |
| 0898T | Noninvasive determination of absolute quantitation of myocardial blood flow (AQMBF), derived from augmentative algorithmic analysis of CMR dataset |
| 0899T | Noninvasive estimate of absolute quantitation of myocardial blood flow (AQMBF), assistive algorithmic analysis of CMR dataset |
| 0900T | AQMBF derived from CMR pharmacologic stress, with interpretation and report |
| Q4311 | Acesso, per square centimeter |
| Q4312 | Acesso ac, per square centimeter |
| Q4314 | Regenelink amniotic membrane allograft, per square centimeter |
| Q4315 | Amchoplast, per square centimeter |
| Q4316 | Vitograft, per square centimeter |
| Q4319 | Sanograft, per square centimeter |
| Q4320 | Pellograft, per square centimeter |
| Q4321 | Renograft, per square centimeter |
| Q4323 | Amniotx, per square centimeter |
| Q4324 | Acapatch, per square centimeter |
| 92972 | Percutaneous transluminal coronary lithotripsy (List separately in addition to code for primary procedure) |
| 97037 | Application of a modality; low-level laser therapy (nonthermal and non-ablative) for postoperative pain reduction |
| 0858T | Externally applied transcranial magnetic stimulation with concomitant measurement of evoked cortical potentials with automated report |
| 0860T | Noncontact near-infrared spectroscopy, image acquisition/interpretation |
| 0811T | Remote multi-day complex uroflowmetry; set-up and patient education |
| 0812T | Remote multi-day complex uroflowmetry; device supply with automated report |
| 0833T | Digitization of glass microscope slides for cytopathology; extended study involving over 5 slides and/or multiple stains |
| 0834T | Digitization of glass microscope slides for cytopathology, evaluation of fine needle aspirate; first evaluation episode |
| 0835T | Digitization of glass microscope slides for cytopathology, additional evaluation episode |
| 0836T | Digitization of glass microscope slides for cytopathology; interpretation and report |
| 0837T | Digitization of glass microscope slides for consultation and report on referred slides |
| 0848T | Digitization of glass microscope slides for in situ hybridization (FISH), per specimen; initial single probe stain procedure |
| 0849T | Digitization of glass microscope slides for in situ hybridization (FISH); each multiplex probe stain procedure |
| 0850T | Digitization of glass microscope slides for morphometric analysis, in situ hybridization (quantitative or semiquantitative), manual |
| 0851T | Digitization of glass microscope slides for morphometric analysis, additional single probe procedure |
| 0852T | Digitization of glass microscope slides for morphometric analysis, each additional single probe procedure |
| 0422U | Sequencing, algorithm reported as a quantitative change from baseline |
| 0423U | Exosome based analysis of 53 sncRNAs by RTqPCR, urine; reported as prostate cancer risk |
| 0424U | Genome rapid sequence analysis each comparator genome (eg, parents) |
| 0430U | Gastroenterology malabsorption evaluation panel, feces |
| 0431U | Glycine receptor alpha1 IgG, serum or CSF, live cell-binding assay, qualitative |
| 0433U | Oncology (prostate), 5 DNA regulatory markers by quantitative PCR, whole blood, algorithm including PSA |
| 0434U | Drug metabolism genomic analysis panel, variant analysis of 25 genes |
| 0435U | Oncology (lung), plasma analysis of 388 proteins using aptamer proteomics |
| 0386U | Nephrology markers (ApoA4, CD5L, IGFBP3) by ELISA, algorithm combining with clinical data |
| 0377U | Oncology (prostate cancer), image analysis of at least 128 histologic features and clinical factors, prognostic algorithm |
| 0380U | RFC1 repeat expansion variant analysis; Always Investigational |
| 0378U | Advanced lipoprotein profile by NMR spectrometry; Always Investigational |
| 0377U | Prostate cancer image analysis prognostic algorithm; Always Investigational |
| 0376U | Ovarian cancer 7-protein biochemical assay with algorithm; Always Investigational |
| 0375U | Genitourinary pathogen multiplex detection; Always Investigational |
| 0374U | Respiratory pathogen multiplex with resistance genes; Always Investigational |
| 0365U | Urine protein biomarker algorithm for bladder cancer risk; Always Investigational |
| 0403U | mRNA 18-gene prostate expression profiling from urine; Always Investigational |
| 53451 | Periurethral transperineal adjustable balloon continence device insertion; Always Investigational |
| 53452 | Unilateral periurethral transperineal adjustable balloon continence device; Always Investigational |
| 53453 | Removal of periurethral transperineal adjustable balloon continence device; Always Investigational |
| A2027 | Matriderm per square centimeter; Always Investigational |
| Q4334 | Amnioplast 1 per square centimeter; Always Investigational |
| 81558 | Transplant mRNA 139-gene expression profiling; Always Investigational |
| 82233 | Beta-amyloid 1-42 assay; Always Investigational |
| 82234 | Neurofilament light chain (NfL); Always Investigational |
| 83884 | Phosphorylated tau (pTau) assays; Always Investigational |
| 84393 | Total tau (tTau); Always Investigational |
| 87513 | H. pylori clarithromycin resistance; Always Investigational |
| 87564 | Mycobacterium tuberculosis rifampin resistance; Always Investigational |
| 87594 | Pneumocystis jirovecii amplified probe technique; Always Investigational |
| 0901T | QTc interval from patient-activated mobile ECG algorithm; Always Investigational |
| 0902T | Algorithmically generated 12-lead ECG from reduced-lead device; Always Investigational |
| 0918T | Removal of permanent cardiac contractility modulation-defibrillation system component(s); Always Investigational |
| 0922T | Removal of permanent cardiac contractility modulation-defibrillation system component(s); Always Investigational |
| 0942T | Cystourethroscopy with removal/replacement of prostatic urethral scaffold; Always Investigational |
| 0943T | 3D contour simulation of liver lesion(s) for image-guided planning; Always Investigational |
| C1738 | 3D anatomical segmentation imaging for preop planning; Always Investigational |
| C8001 | Elastomeric infusion pump (on-q) including catheter and disposables; Always Investigational |
| G0552 | Supply of digital mental health treatment device and initial onboarding; Always Investigational |
| G0553 | Creation of subcutaneous pocket with insertion of 365-day implantable interstitial glucose sensor; Always Investigational |
| G0564 | Removal and reinsertion of 365-day implantable interstitial glucose sensor; Always Investigational |
| 43290 | EGD with deployment of intragastric bariatric balloon; Always Investigational |
| 43291 | EGD with removal of intragastric bariatric balloon(s); Always Investigational |
| 0813T | EGD with volume adjustment of intragastric bariatric balloon; Always Investigational |
| 0531U | Infectious disease NGS for acid-fast bacteria and invasive fungi (673 organisms), plasma; Always Investigational |
| 0532U | Rapid whole genome and mitochondrial sequencing for constitutional/rare disease; Always Investigational |
| 0813T | Esophagogastroduodenoscopy, flexible, transoral, with volume adjustment of intragastric bariatric balloon |
| 0531U | Infectious disease DNA next generation sequencing, plasma (acid-fast bacteria and invasive fungi) |
| 0532U | Genotyping / drug metabolism panel (multiple genes) reported as metabolizer status |
| 0534U | Oncology (prostate), microRNA SNP analysis by RT-PCR of 32 variants, buccal swab |
| 0539U | Transplantation medicine, quantification of donor-derived cell-free DNA using NGS of plasma |
| 0540U | Cardiovascular, cholesterol efflux capacity LC-MS/MS measurement of apolipoproteins |
| 0541U | Nephrology (renal transplant), NMR spectroscopy measurement of urinary metabolites; investigational |
| 0482U | Infectious disease Neisseria gonorrhoeae, ciprofloxacin resistance (gyrA S91F) assay |
| 0483U | Mycoplasma genitalium macrolide sensitivity (23S rRNA point mutation) assay |
| 0484U | Oncology, cell-free DNA and RNA by NGS with interpretative report |
| E0679 | Non-pneumatic compression controller with sequential calibrated gradient |
| E0680 | Non-pneumatic compression controller with sequential calibrated gradient pressure |
| E1905 | Supplies and accessories (e.g., transducer) for low frequency ultrasonic diathermy treatment device |
| K1036 | Computerized ophthalmic diagnostic imaging (eg, OCT) posterior segment with interpretation and report (listed investigational) |
| Q4354 | Abiomend xplus membrane and abiomend xplus hydromembrane, per square centimeter |
| Q4355 | Abiomend xplus membrane and abiomend xplus hydromembrane, per square centimeter |
| Q4356 | Abiomend membrane and abiomend hydromembrane, per square centimeter |
| Q4357 | Xwrap plus, Xwrap dual, per square centimeter |
| Q4358 | Choriply, per square centimeter |
| Q4359 | Unspecified product, per square centimeter |
| Q4360 | Unspecified product, per square centimeter |
| Q4361 | Unspecified product, per square centimeter |
| Q4362 | Unspecified product, per square centimeter |
| Q4363 | Unspecified product, per square centimeter |
| 87626 | Infectious agent detection by nucleic acid (DNA or RNA); human papillomavirus (HPV), separately reported high-risk types and pooled results |
| 0441U | Algorithmic analysis and result reported as an index; Always Investigational |
| 0864T | Low-intensity extracorporeal shock wave therapy involving corpus cavernosum, low energy; Always Investigational |
| 0556U | HealthTrackRx Vaginitis; Always Investigational |
| 0557U | IGoCheck (Blood-Based Colorectal Cancer Test); Always Investigational |
| 0558U | MammoCheck Blood-Based Breast Cancer Test; Always Investigational |
| 0559U | MammoCheck Blood-Based Breast Cancer Test; Always Investigational |
| 0560U | Haystack MRD Baseline and Monitoring; Always Investigational |
| 0565U | EPISEEK MPE (Malignant Pleural Effusion Detection Test); Always Investigational |
| 0566U | Genomic Unity 2.0; Always Investigational |
| 0567U | LucentAD Complete; Always Investigational |
| 0568U | Guardant Reveal; Always Investigational |
| 0569U | i-STAT TBI; Always Investigational |
| 0957T | Revision of sub-scalp implanted electrode array, receiver, and telemetry unit; Always Investigational |
| 0958T | Removal or replacement of magnet from coil assembly connected to sub-scalp EEG monitoring system; Always Investigational |
| 0960T | Shortwave infrared radiation imaging, surgical pathology specimen to assist gross exam for lymph node localization; Always Investigational |
| 0961T | Assistive algorithmic analysis of acoustic and electrocardiogram recording for detection of cardiac dysfunction; Always Investigational |
| 0962T | Anoscopy with directed submucosal injection of bulking agent into anal canal; Always Investigational |
| 0963T | Transanal insertion of endoluminal temporary colorectal anastomosis protection device with vacuum anchoring; Always Investigational |
| 0967T | Insertion or replacement of epicranial neurostimulator system; Always Investigational |
| 0968T | Removal of epicranial neurostimulator system; Always Investigational |
| C9176 | Tc-99m from domestically produced non-heu mo-99 add-on; Always Investigational |
| Q4398 | Summit fx, per square centimeter (add-on); Always Investigational |
| Q4401 | Xwrap 2.0, per square centimeter (add-on); Always Investigational |
| Q4402 | Xwrap dual plus, per square centimeter (add-on); Always Investigational |
| Q4403 | Xwrap hydro plus, per square centimeter (add-on); Always Investigational |
| Q4404 | Xwrap fenestra plus, per square centimeter (add-on); Always Investigational |
| Q4405 | Xwrap fenestra, per square centimeter (add-on); Always Investigational |
| Q4406 | Xwrap fenestra, per square centimeter (add-on); Always Investigational |
| Q4407 | Xwrap tribus, per square centimeter (add-on); Always Investigational |
| 62330 | Decompression, percutaneous, with partial removal of ligamentum flavum, lumbar; additional interspace(s) - Always Investigational |
| 62331 | Decompression; median nerve at carpal tunnel, percutaneous, with intracarpal tunnel balloon dilation, including ultrasound guidance - Always Investigational |
| 64728 | Intracarpal tunnel balloon dilation, including ultrasound guidance - Always Investigational |
| 87183 | Susceptibility studies, antimicrobial agent; carbapenem resistance genes amplified probe - Always Investigational |
| 87627 | Infectious agent detection by nucleic acid; joint space - Always Investigational |
| 0600U | Infectious disease wound infection identification of 65 organisms and 30 resistance genes - Always Investigational |
| 0601U | Periprosthetic joint infection analysis of 11 biomarkers - Always Investigational |
| 98986 | Remote therapeutic monitoring; device(s) supply for cognitive behavioral therapy data transmissions (2-15 days) - Always Investigational |
| 99445 | Remote therapeutic monitoring; daily recording(s) or programmed alerts transmission, 2-15 days in 30-day recording(s) - Always Investigational |
| 0610U | Phenotypic antimicrobial susceptibility testing of positive blood culture using microfluidic sensor technology - Always Investigational |
| 0611U | Oncology (liver), cfDNA methylation analysis of >1000 regions, algorithm reported quantitative - Always Investigational |
| 1014T | Revision or removal, lower esophageal sphincter neurostimulator pulse generator or receiver |
| 1015T | Electronic analysis of implanted neurostimulator pulse generator system, lower esophageal sphincter neurostimulator; intraoperative, with programming |
| 1016T | Electronic analysis of implanted neurostimulator pulse generator system; subsequent, with reprogramming |
| 1018T | Generator/transmitter; subsequent, with reprogramming; Raman spectroscopy of skin lesions... |
| 1020T | Active thoracic irrigation (separate procedure) |
| 1021T | Percutaneous tissue displacement, any method, including imaging |
| 1022T | Percutaneous tissue displacement; intra-abdominal/pelvic structures |
| 1023T | Percutaneous tissue displacement; intrathoracic structures |
| 1024T | Percutaneous tissue displacement; soft tissue |
| A2002 | Bio-connekt wound matrix, per square centimeter |
| 0159T | Listed with ExceptionsNotes = Always Investigational |
| 0159U | Listed with ExceptionsNotes = Always Investigational |
| 0160U | Listed with ExceptionsNotes = Always Investigational |
| 0162U | Hereditary colon cancer (Lynch syndrome), targeted mRNA sequence analysis panel (MLH1, MSH2, MSH6, PMS2) - ExceptionsNotes = Always Investigational |
| 0174T | Listed with ExceptionsNotes = Always Investigational |
| 0184T | Excision of rectal tumor, transanal endoscopic microsurgical approach - ExceptionsNotes = Always Investigational |
| 0219T | Placement of a posterior intrafacet implant(s) - ExceptionsNotes = Always Investigational |
| 0222T | Injection(s), platelet rich plasma, any tissue - ExceptionsNotes = Always Investigational |
| 0232T | Skin advanced glycation endproducts measurement - ExceptionsNotes = Always Investigational |
| 0233T | Skin advanced glycation endproducts measurement by multi-wavelength fluorescent spectroscopy - ExceptionsNotes = Always Investigational |
| 0235T | Transluminal peripheral atherectomy (various anatomic sites) - ExceptionsNotes = Always Investigational |
| 0267T | Implantation or replacement of carotid sinus baroreflex activation device; pulse generator only - ExceptionsNotes = Always Investigational |
| 0268T | Revision or removal of carotid sinus baroreflex activation device; total system - ExceptionsNotes = Always Investigational |
| 0278T | Transcutaneous Electrical Modulation Pain Reprocessing, Each Treatment Session - ExceptionsNotes = Always Investigational |
| 0290T | Vagus Nerve Blocking; Laparoscopic Implant Neurostim Electrode Array - ExceptionsNotes = Always Investigational |
| 0312T | Vagus Nerve Blocking; Implantation/Revision/Removal codes - ExceptionsNotes = Always Investigational |
| 0320T | Insertion of subcutaneous defibrillator electrode - ExceptionsNotes = Always Investigational |
| 0330T | Tear film imaging / Myocardial sympathetic innervation imaging - ExceptionsNotes = Always Investigational |
| 0347T | Placement of interstitial device(s) in bone for radiostereometric analysis - ExceptionsNotes = Always Investigational |
| 0350T | Radiostereometric analysis (RSA) - ExceptionsNotes = Always Investigational |
| 0351T | Optical coherence tomography of breast or axillary lymph node, excised tissue - ExceptionsNotes = Always Investigational |
| 0358T | Bioelectrical impedance analysis whole body composition assessment; ExceptionsNotes = Always Investigational |
| 0377T | Visual field assessment with remote data transmission - ExceptionsNotes = Always Investigational |
| 0379T | Programming device evaluation with iterative adjustment - ExceptionsNotes = Always Investigational |
| 0414T | Removal/repositioning of cardiac contractility modulation device leads - ExceptionsNotes = Always Investigational |
| 0420T | Tactile breast imaging by computer-aided tactile sensors - ExceptionsNotes = Always Investigational |
| 0425T | Insertion or replacement of neurostimulator system for central sleep apnea; sensing lead only - ExceptionsNotes = Always Investigational |
| 0426T | Insertion or replacement of neurostimulator system for central sleep apnea; stimulation lead only - ExceptionsNotes = Always Investigational |
| 0443T | Real time spectral analysis of prostate tissue by fluorescence spectroscopy - ExceptionsNotes = Always Investigational |
| 0444T | Initial placement of a drug-eluting ocular insert under eyelids - ExceptionsNotes = Always Investigational |
| 0446T | Creation of subcutaneous pocket with insertion of implantable interstitial glucose sensor - ExceptionsNotes = Always Investigational |
| 0451T | Insertion or replacement of a permanently implantable aortic counterpulsation ventricular assist system, endovascular approach - ExceptionsNotes = Always Investigational |
| 0452T | Programming of sensing and therapeutic parameters; aortic counterpulsation system - ExceptionsNotes = Always Investigational |
| 0453T | Insertion/replacement of aortic counterpulsation assist system; mechano-electrical interface - ExceptionsNotes = Always Investigational |
| 0465T | Insertion of chest wall respiratory sensor electrode or electrode array - ExceptionsNotes = Always Investigational |
| 0469T | Retinal polarization scan, ocular screening - ExceptionsNotes = Always Investigational |
| 0458T | Removal of permanently implantable aortic counterpulsation ventricular assist system; subcutaneous electrode |
| 0459T | Relocation of skin pocket with replacement of implanted aortic counterpulsation ventricular assist device |
| 0460T | Repositioning of previously implanted aortic counterpulsation ventricular assist device; subcutaneous electrode |
| 0461T | Programming device evaluation (in person) with iterative adjustment... implantable aortic counterpulsation ventricular assist system |
| 0462T | Interrogation device evaluation (in person) with analysis... implantable aortic counterpulsation ventricular assist system |
| 0463T | Interrogation device evaluation... implantable aortic counterpulsation ventricular assist system |
| 0464T | Visual evoked potential, testing for glaucoma... |
| 0465T | Suprachoroidal injection of a pharmacologic agent (does not include supply of medication) |
| 0466T | Insertion of chest wall respiratory sensor electrode or electrode array |
| 0467T | Revision or replacement of chest wall respiratory sensor electrode or electrode array |
| 31649 | Insertion Of Bronchial Valve(s), Each Addl Lobe |
| 31651 | Bronchoscopy; With Bronchial Thermoplasty, 1 Lobe |
| 31660 | Bronchoscopy; With Bronchial Thermoplasty, 1 Lobe |
| 31661 | Bronchoscopy; With Bronchial Thermoplasty, 2 Or More Lobes |
| 33289 | Transcatheter implantation of wireless pulmonary artery pressure sensor |
| 43206 | Esophagoscopy, Rigid Or Flexible; With Optical Endomicroscopy |
| 43252 | Upper Gastrointestinal Endoscopy; With Optical Endomicroscopy |
| 62287 | Aspiration/Decompression, Percutaneous, Nucleus Pulposus, Any Method |
| 62292 | Injection procedure for chemonucleolysis, including discography, intervertebral disc, single or multiple levels, lumbar |
| 81175 | ASXL1 gene analysis; full gene sequence |
| 81176 | ASXL1 gene analysis; targeted sequence analysis |
| 81225 | CYP2C19 gene analysis; common variants |
| 81226 | CYP2D6 gene analysis; common variants |
| 86910 | Blood typing, for paternity testing, per individual; ABO, Rh and MN |
| 86911 | Blood typing, for paternity testing, per individual; each additional antigen |
| 92065 | Orthoptic &/Or Pleoptic Training |
| 92145 | Corneal hysteresis determination, by air impulse stimulation, with interpretation and report |
| 93050 | Arterial pressure waveform analysis for assessment of central arterial pressures |
| 95943 | Simultaneous measures of parasympathetic and sympathetic function with HR and BP measures |
| 95980 | Electronic Analysis of Implanted Gastric Neurostimulator Pulse Generator/Transmitter; Intraoperative, with Programming |
| 96931 | Reflectance confocal microscopy (RCM) for cellular and sub-cellular imaging of skin; image acquisition and interpretation and report, first lesion |
| C9353 | Microporous collagen implantable slit tube (NeuraWrap Nerve Protector), per cm length |
| C9354 | Acellular pericardial tissue matrix of nonhuman origin (Veritas), per sq cm |
| C9364 | Porcine implant, Permacol, per square centimeter |
| C9747 | Bronchoscopy, rigid or flexible, transbronchial ablation of lesion(s) by microwave energy |
| C9751 | Destruction of intraosseous basivertebral nerve, first two vertebral bodies, including imaging guidance |
| E0446 | Incontinence treatment system, pelvic floor stimulator, monitor, sensor, and/or trainer |
| E0740 | Nerve Stimulator For Treatment N&V |
| E1816 | Static progressive stretch ankle device |
| G0428 | Collagen meniscus implant procedure (Menaflex) / Low frequency ultrasonic diathermy device for home use (contextual grouping) |
| K1004 | Prolotherapy |
| M0076 | Platelet Rich Plasma Unit |
| P9020 | Platelet Rich Plasma Unit (alternate listing) |
| Q4168 | Amnioband, 1 mg |
| Q4169 | Artacent wound, per square centimeter |
| Q4170 | Cygnus, per square centimeter |
| Q4171 | Interfyl, 1 mg |
| Q4172 | Puraply or puraply am, per square centimeter |
| Q4173 | Palingen or palingen xplus, per square centimeter; palingen or promatrx, 0.36 mg per 0.25 cc |
| Q4174 | Palingen or promatrx, 0.36 mg per 0.25 cc; Miroderm, per square centimeter |
| Q4175 | Miroderm, per square centimeter; NeoPatch |
| Q4176 | NeoPatch |
| Q4177 | FlowerAmnioFlo |
| Q4178 | FlowerAmnioPatch |
| S2348 | Decompress disc RF lumbar (percutaneous decompression of nucleus pulposus using radiofrequency energy) |
| S2350 | Diskectomy, anterior, with decompression of spinal cord and/or nerve root(s), lumbar, single interspace |
| S3650 | Saliva test, hormone level; during menopause |
| S3652 | Saliva test, hormone level; to assess preterm labor risk |
| S3722 | Dose Optimization By Area Under The Curve (AUC) Analysis, For Infusional 5-Fluorouracil |
| S8040 | Topographic Brain Mapping |
| S8130 | Interferential current stimulator, 2 channel |
| S8131 | Interferential current stimulator, 4 channel |
| S8930 | Interferential current stimulator, 4 channel Auricular electrostimulation |
| S9090 | Application of a modality; low-level laser; each 15 minutes |
Billing, prior authorization, and documentation guidance
Prior authorization for investigational codes
Prior authorization for the temporary CPT/HCPCS and other procedure codes listed as “Always Investigational” is not expected to result in coverage; these codes remain designated Always Investigational and are not payable unless the policy is changed.
Investigational code billing guidance — denial risk
Billing services identified in the policy that are annotated 'Always Investigational' may lead to claim denial; providers should not expect routine payment when submitting these codes.
Prior authorization expectation for listed investigational codes
Codes in the list that are designated 'Always Investigational' would require prior authorization if submitted, but the policy indicates these items are expected to be non‑covered even with authorization.
Prior authorization for investigational devices will not make them covered
Device and supply HCPCS codes shown as Always Investigational will not be rendered covered by prior authorization; prior authorization does not convert investigational device entries into covered items.
Prior authorization not applicable for Always Investigational codes
Codes that are explicitly labeled 'Always Investigational' are not eligible for prior authorization to obtain coverage; prior authorization does not change the investigational designation.
Remote therapeutic/physiologic monitoring codes are investigational
Remote therapeutic and remote physiologic monitoring codes listed in this policy are marked Always Investigational; prior authorization will not make these services covered.
Prior authorization will not change investigational/cosmetic status
Prior authorization alone does not convert services designated Always Investigational or Always Cosmetic into payable services; authorization should not be used as a substitute for coverage criteria compliance.
- The policy explicitly states that items in these code groups are Always Investigational or Always Cosmetic and that prior authorization will not render them covered.
Investigational implantable aortic counterpulsation device codes — not covered by authorization
Implantable aortic counterpulsation ventricular assist system codes are designated Always Investigational; prior authorization is not described as enabling coverage for these devices.
- Examples: 0451T, 0452T, 0453T, 0456T are marked Always Investigational.
Prior authorization not indicated for investigational/cosmetic codes
Prior authorization is not indicated for codes the policy marks Always Investigational or Always Cosmetic because authorization will not make these services covered.
- The policy lists many device/programming, sensor, and novel procedure codes with ExceptionsNotes = Always Investigational.
Prior authorization not applicable for listed investigational/cosmetic codes
The policy reiterates that prior authorization does not render codes designated Always Investigational or Always Cosmetic payable; providers should not expect coverage after prior authorization.
- A long list of CPT/HCPCS codes in chunk 180 are designated Always Investigational/Always Cosmetic and prior authorization will not change coverage.
Prior authorization does not convert investigational status to payable
Prior authorization does not convert the investigational designation into coverage; listed codes remain not payable despite any authorization attempt.
- Examples: numerous Q‑codes (e.g., Q4168 and related Q4xxx entries) are explicitly noted as Always Investigational and not payable with authorization.
Provider action — see related items
(No specific action required; placeholder entry preserved from inventory.)
Provider action — see related items
(No specific action required; placeholder entry preserved from inventory.)
Provider action — see related items
(No specific action required; placeholder entry preserved from inventory.)
Provider action — see related items
(No specific action required; placeholder entry preserved from inventory.)
Digital mental health device services marked Always Investigational
Digital mental health treatment device supply and monthly treatment management codes are listed as Always Investigational and are not covered; do not expect payment or step‑therapy pathways for these codes.
Provider action — see related items
(No specific action required; placeholder entry preserved from inventory.)
Provider action — see related items
(No specific action required; placeholder entry preserved from inventory.)
Provider action — see related items
(No specific action required; placeholder entry preserved from inventory.)
Provider action — see related items
(No specific action required; placeholder entry preserved from inventory.)
Provider action — see related items
(No specific action required; placeholder entry preserved from inventory.)
Provider action — see related items
(No specific action required; placeholder entry preserved from inventory.)
Provider action — see related items
(No specific action required; placeholder entry preserved from inventory.)
Policy applies to Moda Health Commercial Group and Individual Members
This policy applies to Moda Health Commercial Group and Individual Members; providers should reference this policy when submitting claims for listed services as these are designated investigational or cosmetic and are not covered for the indicated member types.
Provider action — see related items
(No specific action required; placeholder entry preserved from inventory.)
Provider action — see related items
(No specific action required; placeholder entry preserved from inventory.)
Documentation expectation for amniotic membrane Q‑codes
When billing HCPCS Q‑codes for amniotic membrane/amnion products (for example Q4314–Q4326 and many Q4xxx entries), expect that these codes are designated Always Investigational; submit supporting documentation if desired but anticipate documentation requests or claim denial.
Documentation note — listed investigational services
When submitting services for codes listed as Always Investigational, include clear justification of medical necessity in documentation; however, the policy marks these services investigational which indicates coverage is not supported per policy.
Documentation expectation for investigational services
Providers should expect claims for codes listed in this section (for example 43290, 43291 and multiple U, Q, E and other codes) to be treated as investigational; maintain supporting documentation but coverage is not provided per this policy.
Documentation for sub‑scalp EEG services — detail service and programming
When reporting services for implanted sub‑scalp continuous bilateral EEG monitoring systems and related programming/analysis, submit detailed service descriptions and codes as listed; note these services are marked Always Investigational in this policy segment.
- Include programming, analysis, and duration details when billing the listed monitoring and programming entries.
Documentation — standard coding identification only
No additional documentation requirements beyond identifying the service by the listed code are specified in these chunks; follow standard claim documentation but recognize investigational designation remains.
Documentation implication — justify medical necessity though likely insufficient
Many codes include an ExceptionsNotes field marking them as Always Investigational; providers should still ensure medical‑necessity justification is documented though the policy marks them investigational and coverage is not supported.
Documentation note — Always Cosmetic codes are non‑covered
Codes explicitly labeled 'Always Cosmetic' (for example dermabrasion, chemical peels, blepharoplasty and related entries) are non‑covered cosmetic procedures; documentation supporting medical necessity is unlikely to change coverage.
- Examples: 15781–15783 (dermabrasion), 15788–15793 (chemical peels), 15820–15821 (blepharoplasty).
Use listed code/service descriptions when preparing documentation
Use the exact code and service descriptions provided in the policy when preparing documentation and claims for the listed items; the document pairs service descriptions with each code.
Documentation will not change coverage for Always Investigational services
Documentation submitted for services billed with codes labeled 'Always Investigational' will not be sufficient to obtain coverage because the policy designates these services as investigational and not covered.
Denial risk — investigational‑designated codes may be denied
Claims submitted with codes labeled Always Investigational are at risk for denial as not covered; submit claims with awareness that denial is likely for investigational‑designated codes.
Denial risk for investigational items
Services and items explicitly marked Always Investigational in the policy may be denied when billed to Moda Health Commercial Group and Individual Members; providers should not expect payment.
Denial risk for investigational/not covered codes
Claims submitted with codes listed as 'Always Investigational' or 'Not covered' are at elevated risk of denial for Moda Health Commercial Group and Individual Members; verify coverage stance before billing.
Denial risk — Always Investigational T‑codes
Claims for procedures listed with the note 'Always Investigational' (for example selected T‑codes such as 0897T–0900T) are subject to denial per the policy.
Claims for listed services/codes are at risk for denial
Claims for the listed services and codes in multiple sections of this document are designated Always Investigational and are at risk for denial when billed for covered members.
- Examples include device, implant, and biomarker codes (e.g., 0403U, 53451–53453, Q4334–Q4336).
Document purpose and scope
Sample temporary codes and additional investigational entries are included in the policy as examples of investigational-designated codes. The document background explains it enumerates many specific procedures, implants, tests, imaging techniques, and product codes that the payer considers always investigational or cosmetic for Moda Health Commercial members.
Key terms and payer designations
Policy updates and effective dates
Policy effective and last reviewed on 06/18/2026 per document header; applies to Moda Health Commercial Group and Individual Members.
Document notes an update cycle referencing April 1, 2024 and July 1, 2024 in a coding entry — indicating prior updates were made in 2024.
Source contains an 'Updated April 1, 2024' entry in coding/module context indicating prior revisions on this date.
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