CPT code 0441U is a Proprietary Laboratory Analyses (PLA) code for the IntelliSep® test (Cytovale®), a semiquantitative biomechanical assessment performed on a whole blood specimen that uses deformability cytometry and algorithmic analysis to produce an index categorizing a patient’s likelihood of developing sepsis; service type: specialized laboratory diagnostic test using whole blood with algorithmic result reporting; typical site of service: clinical or hospital laboratory or acute care setting where blood draws and rapid diagnostic testing are available.

For related coverage guidance, see recent payer policy updates: RTM Testing of Homocysteine Metabolism-Related Conditions, Multimarker Serum Testing Related to Ovarian Cancer, Genomic Profiling for Selecting Targeted Cancer Therapies.