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    OpenPayerBilling CodesInjection, Drainage, or Aspiration Procedures on the Spine and Spinal CordCPT cpt-62292-chemonucleolysis-lumbar-disc-with-discography
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    CPT 62292: Chemonucleolysis of Lumbar Disc with Discography

    Medicare pays $522 on average nationally for this procedure.

    CPT code 62292 describes chemonucleolysis of a lumbar intervertebral disc with fluoroscopic discography to localize the affected level and target injection of an enzyme into the nucleus pulposus to dissolve herniated disc material; this is an image-guided interventional spine procedure typically performed in an ambulatory surgical center or hospital outpatient setting to relieve radicular back pain caused by a bulging or herniated lumbar disc.

    For related coverage guidance, see recent payer policy updates: Dental Anesthesia Services, Anesthesia Services for Interventional Pain Management Procedures in an Adult, General Anesthesia and Conscious Sedation Services.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A 45-year-old patient presents with persistent unilateral low back pain radiating to the leg and sensory changes consistent with L4–L5 radiculopathy after conservative care (physical therapy, NSAIDs, and epidural steroid injection) failed over 6–12 weeks. Imaging (MRI) demonstrates a contained posterolateral lumbar disc herniation at L4–L5 with corresponding nerve root compression. The interventional spine physician schedules chemonucleolysis under fluoroscopic guidance to dissolve the nucleus pulposus and relieve nerve root impingement. In the procedural workflow the patient is positioned prone on the fluoroscopy table, sedation and local anesthesia are administered, and a diagnostic discography is performed to confirm the symptomatic disc level and annular disruption. Under live fluoroscopy the provider advances a spinal needle into the target disc, injects the chemonucleolytic enzyme, documents intradiscal contrast pattern, monitors for pain provocation, and completes the case with post-procedure observation. Typical site of service is an ambulatory surgery center or hospital outpatient department where fluoroscopy, sedation, and perioperative monitoring are available. Common patient considerations include allergy screening, coagulation status, and informed consent discussing risks such as infection, chemical radiculitis, or needle-related complications.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    62280Injection, diagnostic or therapeutic agent, spinal canal, lumbar; epiduralPerformed before or instead of chemonucleolysis for epidural steroid delivery for radicular pain management.
    72275Injection procedure for discography, lumbar; provocative discography, inclusive of needle placement(s) and contrast injectionDiscography codes may be used for diagnostic provocation; 62292 includes discography as part of chemonucleolysis so careful coding to avoid duplication is required.
    77002Fluoroscopic guidance for needle placement (e.g., biopsy, aspiration, injection), spine or paraspinous region; lumbarFluoroscopic guidance is integral to 62292; some payers require separate reporting of guidance when billed distinct from the primary procedure.
    72295Discography, lumbar, computed tomography (CT) guidedAlternative imaging-guided discography performed when CT guidance is used in planning or diagnosis prior to chemonucleolysis.
    62323Injection(s), including anesthetic agent and/or steroid, transforaminal epidural or perineural, lumbar or sacral; single levelOften performed in the same episode of care as diagnostic injections to manage radicular symptoms or to localize symptomatic levels prior to deciding on chemonucleolysis.

    Related Modifiers

    10 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    73Modifier 73 indicates a facility-level outpatient hospital or ASC procedure that was discontinued after the patient was prepared and taken to the procedure/operating room but before any anesthesia…- When to use: Apply CPT modifier 73 on the FACILITY (outpatient hospital or ASC) claim when the patient has been fully prepared and physically taken into the procedure/operating room but the…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    81Modifier -81 indicates a physician served as a minimal assistant surgeon for part—not all—of an operative procedure. Use when a physician’s assisting role is limited and does not represent full…- Use CPT modifier -81 when a physician acts as a minimum assistant surgeon who assists during only part (a limited portion) of an operative procedure; append -81 to the primary surgical CPT code to…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    2084P0800X
    2086S0105X
    207L00000X
    363LF0000X
    103T00000X
    246ZX2200X
    251B00000X
    207RE0101X

    Related Payer Policy Updates

    Specialty: Anesthesiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Dental Anesthesia ServicesProvidence Health Plan2026-10-01
    Anesthesia Services for Interventional Pain Management Procedures in an AdultCigna2026-09-15
    General Anesthesia and Conscious Sedation ServicesUnitedHealthcare2026-09-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Intravenous Anesthetics for the Treatment of Chronic Pain and Psychiatric or Substance Use DisordersPremera Bluecross2026-07-01
    Elective Inpatient Services (for Idaho Only)UnitedHealthcare2026-06-01
    Sites of Servicepriority health2026-06-01
    Coverage for Ambulatory Surgery Unit (ASU)/Outpatient Facility and Anesthesia for Dental Servicesuniverahealthcare2026-05-21

    Related Codes

    CPT-62263-EPIDURAL-NEUROLYSIS-ADHESIOLYSIS-RACZ-CATHETER

    CPT 62263: Epidural Adhesiolysis (Racz Catheter), Multi-Session

    CPT-62264-EPIDURAL-NEUROLYSIS-RACZ-CATHETER-ADHESION-LYSIS

    CPT 62264: Epidural Adhesiolysis (Racz Catheter)

    CPT-62267-INTERVERTEBRAL-DISC-PARAVERTEBRAL-ASPIRATION

    CPT 62267: Intervertebral Disc or Paravertebral Aspiration

    CPT-62268-SPINAL-CYST-SYRINX-ASPIRATION

    CPT 62268: Aspiration of Spinal Cord Cyst or Syrinx

    CPT-62269-SPINAL-CORD-NEEDLE-BIOPSY

    CPT 62269: Percutaneous Spinal Cord Needle Biopsy

    CPT-62270-DIAGNOSTIC-SPINAL-PUNCTURE-CSF-SAMPLING

    CPT 62270: Diagnostic Spinal Puncture for CSF Sampling

    CPT-62272-LUMBAR-PUNCTURE-SPINAL-TAP-CSF-WITHDRAWAL

    CPT 62272: Lumbar Puncture (Spinal Tap) for CSF Removal

    CPT-62273-EPIDURAL-BLOOD-PATCH-FOR-CSF-LEAK

    CPT 62273: Epidural Blood Patch for CSF Leak

    CPT-62280-NEUROLYTIC-SUBARACHNOID-INJECTION-FOR-SEVERE-PAIN

    CPT 62280: Subarachnoid Neurolytic Injection

    CPT-62281-CERVICAL-THORACIC-EPIDURAL-NEUROLYTIC-INJECTION

    CPT 62281: Cervical/Thoracic Epidural Neurolytic Injection

    Showing 1–10 of 30

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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