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    v1.0.31
    OpenPayerBilling CodesOutpatient PPSHCPCS hcpcs-level-ii-c1763-non-human-connective-tissue-graft
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    HCPCS C1763: Connective Tissue, Non-Human (Includes Synthetic)

    HCPCS Level II code C1763 describes a non-human or synthetic connective tissue graft product used in surgical repair or reconstruction; the service is supply of a biologic/synthetic connective tissue implant typically used in operative surgical settings such as hospital operating rooms, ambulatory surgery centers, or specialty surgical clinics for procedures requiring tissue augmentation or soft-tissue reinforcement.

    For related coverage guidance, see recent payer policy updates: Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillation, Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillation, Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillation.

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    Clinical & Coding Specifications

    Clinical Context

    A patient with a full-thickness soft-tissue defect after trauma or surgical debridement presents for reconstruction. The surgeon selects a non-human connective tissue graft (C1763) — for example, a biologic dermal matrix of porcine or bovine origin or a synthetic collagen scaffold — to reinforce soft tissue, provide coverage, and support wound healing. Typical workflow: preoperative evaluation in the outpatient clinic with documentation of the wound size, prior infection status, and indication for grafting; informed consent and selection of the graft product; intraoperative placement of the connective tissue graft during wound closure or reconstructive procedure in an operating room or ambulatory surgery center; securement of the graft to native tissues, adjunctive procedures as needed (debridement, irrigation, hemostasis); postoperative wound care with follow-up visits for dressing changes and assessment of graft incorporation.

    Typical site of service: hospital operating room, ambulatory surgery center, or wound care procedure room.

    Typical patient scenario: a 58-year-old patient with a chronic non-healing lower extremity ulcer after vascular intervention undergoes surgical debridement and placement of a non-human connective tissue matrix to promote tissue regeneration and provide scaffold for re-epithelialization. The procedure is billed with product code C1763 and may be accompanied by surgical CPT codes for debridement or excisional procedures and appropriate modifiers reflecting circumstances such as bilateral site, assistant surgeon, or unusual procedural difficulty.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    11042Debridement, subcutaneous tissue (first 20 sq cm or less)Frequently performed immediately before graft placement to remove devitalized tissue and prepare the wound bed.
    15271Application of skin substitute graft to trunk, arms, legs; first 100 sq cm or lessApplied when biologic or synthetic dermal substitutes are used for coverage; may represent an alternative or companion procedure to billing the implant code.
    13100Repair, intermediate, face, ears, eyelids, nose, lips; 2.5 cm or lessSmaller soft-tissue closures that may be performed in conjunction with placement of connective tissue matrix in reconstructive repairs.
    97605Negative pressure wound therapy (NPWT) per wound; debridement not includedOften used postoperatively to promote graft adherence and wound healing after placement of a biologic matrix.
    20926Tissue grafts, soft tissue, muscle and/or fascia; trunkUsed when additional autologous soft-tissue grafting or flap procedures are performed alongside the non-human connective tissue implant.

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208000000X
    207K00000X
    207L00000X
    363L00000X
    2471V0105X
    2084F0202X
    163WP0200X
    163WC1500X

    Related Payer Policy Updates

    Specialty: Cardiology1 / 3

    10 rows

    PolicyPayerEffective Date
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2027-02-05
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2027-02-05
    Percutaneous Left Atrial Appendage Closure Devices for Stroke Prevention in Atrial Fibrillationpremerabluecrossofwashington2027-02-05
    Percutaneous Left Atrial Appendage Closure - Medical PolicyHealth-New-England2027-02-01
    Transcatheter Mitral Valve Repair Medical PolicyHealth-New-England2027-02-01
    Cardiac Electrophysiological (EP) Studies and Cardiac Ablation of Abnormal Electrical RhythmsCigna2027-01-15
    IvabradineCigna2026-11-15
    Tilt Table TestingCigna2026-11-15
    Outpatient Cardiology Procedures for EviCore Arrangement (for Oxford Only)Colorado Rocky Mountain Health Plans2026-11-01
    Biomarkers for Myocardial Infarction and Chronic Heart Failure Reimbursement PolicyHealthfirst2026-11-01

    Related Codes

    HCPCS-C1713-IMPLANTABLE-ANCHOR-SCREW-BONE-FIXATION

    HCPCS C1713: Anchor/Screw for Bone or Soft Tissue Fixation (Implantable)

    HCPCS-C1714-TRANSLUMINAL-DIRECTIONAL-ATHERECTOMY-CATHETER

    HCPCS C1714: Catheter, transluminal atherectomy, directional

    HCPCS-C1715-BRACHYTHERAPY-NEEDLE

    HCPCS C1715: Brachytherapy Needle

    HCPCS-C1716-BRACHYTHERAPY-GOLD-198-SOURCE

    HCPCS C1716: Brachytherapy Source, Gold-198, Per Source

    HCPCS-C1717-HDR-BRACHYTHERAPY-IRIDIUM-192-SOURCE

    HCPCS C1717: HDR Iridium-192 Brachytherapy Source, Per Source

    HCPCS-C1719-BRACHYTHERAPY-IRIDIUM-192-SOURCE-NON-STRANDED

    HCPCS C1719: Brachytherapy Source, Iridium-192, Non-Stranded

    HCPCS-C1721-IMPLANTABLE-DUAL-CHAMBER-CARDIOVERTER-DEFIBRILLATOR

    HCPCS C1721: Cardioverter-Defibrillator, Dual Chamber (Implantable)

    HCPCS-C1724-ROTATIONAL-TRANSLUMINAL-ATHERECTOMY-CATHETER

    HCPCS Level II C1724: Rotational Transluminal Atherectomy Catheter

    HCPCS-C1725-TRANSLUMINAL-ANGIOPLASTY-CATHETER-NON-LASER

    HCPCS Level II C1725: Transluminal Angioplasty Catheter, Non-Laser

    HCPCS-C1726-NON-VASCULAR-BALLOON-DILATATION-CATHETER

    HCPCS C1726: Catheter, Balloon Dilatation, Non-Vascular

    Showing 1–10 of 603

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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