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    v1.0.31
    OpenPayerBilling CodesDurable Medical EquipmentHCPCS hcpcs-e0680-non-pneumatic-compression-controller-sequential-pressure
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    HCPCS E0680: Non-pneumatic Compression Controller with Sequential Gradient Pressure

    HCPCS Level II code E0680 describes a non-pneumatic compression controller with sequential calibrated gradient pressure, a durable medical equipment device used to provide sequential gradient compression therapy for conditions such as lymphedema or venous insufficiency; service type is durable medical equipment (DME) — compression therapy device, and the typical site of service is outpatient clinics, home health settings, or patient residences where patients receive or use DME for limb compression.

    For related coverage guidance, see recent payer policy updates: Sleep Position Trainer, Hospital Beds Corporate Medical Policy, Continuous Passive Motion Devices with Remote Monitoring or Adaptive Capabilities.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 65-year-old individual with chronic venous insufficiency and recurrent lower-extremity edema who presents to a vascular clinic for management of symptomatic leg swelling and risk reduction for venous ulcers. After clinical evaluation including history, physical exam, and duplex ultrasound to exclude deep vein thrombosis, the vascular specialist prescribes a non-pneumatic sequential compression device described by billing code E0680 for outpatient use. The device provides sequential calibrated gradient pressure to the lower extremities to improve venous and lymphatic return.

    The clinical workflow begins with the ordering clinician (vascular surgeon, interventional cardiologist, wound care physician, or physiatrist) documenting medical necessity and objective findings such as persistent edema refractory to compression stockings, healed or active venous ulcer, or lymphatic insufficiency. A durable medical equipment (DME) supplier verifies the prescription, obtains insurance prior authorization when required, and delivers device training to the patient and caregiver. Follow-up visits assess symptom improvement, skin integrity, and device tolerance; changes in therapy or additional interventions (wound care, compression stockings, or referral for endovenous intervention) are documented as clinically indicated.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    29540Application of multilayer compression, leg (e.g., for venous insufficiency)May be performed before or alongside device prescription for acute edema or wound management; documents compression therapy application.
    99406Smoking and tobacco use cessation counseling, intermediate, greater than 3 minutes up to 10 minutesPerformed in clinic visits addressing wound healing risk factors; often part of comprehensive management but not specific to device billing.
    97039Unlisted modality (specify) - used for complex manual lymphatic drainage when no specific code existsMay be billed when advanced lymphatic therapies are provided in conjunction with device use.
    99070Supplies and materials provided by physician over and above those usually included with the office visitUsed when additional supplies (specialized garments or interface liners) are supplied with the device fitting.
    G0283Electrical stimulation (unattended) to one or more areas for wound care as part of adjunctive therapyOccasionally used in comprehensive wound clinics where DME like E0680 is part of a multimodal regimen.

    Related Modifiers

    7 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…
    82Modifier 82 is appended to a surgical CPT code to indicate that an attending physician acted as an assistant because a qualified resident surgeon was unavailable. In teaching hospitals it documents…- When to use: Append modifier 82 in teaching-hospital settings to indicate a physician served as an assistant surgeon because a qualified resident surgeon was unavailable (includes situations where…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207RG0300X
    208600000X
    207P00000X
    363LF0000X
    282N00000X
    225XF0002X
    163WH0200X
    207RP1002X

    Related Payer Policy Updates

    Specialty: Durable Medical Equipment (DME)1 / 3

    10 rows

    PolicyPayerEffective Date
    Sleep Position Trainerregence2027-01-01
    Hospital Beds Corporate Medical Policybcbsvermont2027-01-01
    Continuous Passive Motion Devices with Remote Monitoring or Adaptive CapabilitiesBlue Cross Blue Shield - Rhode Island2026-12-01
    Bone Growth StimulatorsMass General Brigham Health Plan2026-12-01
    Prior Authorization for Durable Medical Equipment (DME)Blue Cross Blue Shield - Rhode Island2026-12-01
    Patient Liftsuniverahealthcare2026-11-16
    Tonic Motor Activation (TOMAC) for Restless Legs Syndromeregence2026-11-01
    Functional Neuromuscular Electrical Stimulationregence2026-11-01
    Noninvasive Ventilators in the Home Settingregence2026-11-01
    Medical Car SeatsCareSource2026-11-01

    Related Codes

    HCPCS-E0100-CANE-DURABLE-MEDICAL-EQUIPMENT-AMBULATION

    HCPCS E0100: Cane, Adjustable or Fixed, With Tip

    HCPCS-E0105-CANE-QUAD-THREE-PRONG-MOBILITY-AID

    HCPCS Level II E0105: Cane, Quad or Three-Prong, Includes Tips

    HCPCS-E0110-FOREARM-CRUTCHES-PAIR-DME-MOBILITY

    HCPCS Level II E0110: Forearm Crutches, Pair, Complete with Tips and Handgrips

    HCPCS-E0111-CRUTCH-FOREARM-DURABLE-MEDICAL-EQUIPMENT

    HCPCS Level II E0111: Crutch, Forearm, With Tip and Handgrips

    HCPCS-E0112-UNDERARM-WOOD-CRUTCHES-PAIR

    HCPCS Level II E0112: Underarm Wooden Crutches, Pair

    HCPCS-E0113-CRUTCH-UNDERARM-WOOD-ADJUSTABLE-FIXED-WITH-PAD-TIP-HANDGRIP

    HCPCS Level II E0113: Crutch Underarm, Wood, Adjustable or Fixed

    HCPCS-E0114-UNDERARM-CRUTCHES-PAIR-ADJUSTABLE-FIXED

    HCPCS Level II E0114: Underarm (Axillary) Crutches, Adjustable or Fixed, Pair

    HCPCS-E0116-UNDERARM-CRUTCH-NON-WOOD-ADJUSTABLE-FIXED

    HCPCS E0116: Underarm Crutch, Non-Wood, Adjustable/Fixed with Pad

    HCPCS-E0117-ARTICULATING-SPRING-ASSISTED-UNDERARM-CRUTCH

    HCPCS Level II E0117: Crutch, Underarm, Articulating, Spring-Assisted

    HCPCS-E0118-LOWER-LEG-PLATFORM-CRUTCH-SUBSTITUTE

    HCPCS E0118: Crutch Substitute, Lower Leg Platform

    Showing 1–10 of 670

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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