Expanded Fertility Services - Medical Coverage Policy
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Policy governing coverage, prior authorization, and medical necessity criteria for expanded fertility services purchased by self-funded employer clients of Blue Cross & Blue Shield of Rhode Island; applies only to members with expanded fertility coverage. Providers should refer to members' benefit booklets for plan-specific details.
No material clinical or coverage changes in this revision.
Coverage and Medical Necessity Criteria
Multiple Embryo Transfer (MET) Medical Necessity
MET is medically necessary when ONE of the following is met:
Infertility Definition and IVF Eligibility (AFAB)
Infertility is defined when ALL of the following are met:
Continuation of IVF after 4 cycles
Continued IVF services after 4 consecutive unsuccessful cycles are considered medically necessary when ALL of the following are provided:
Cryopreservation Coverage
Cryopreservation is covered under these conditions:
Elective preservation: egg/oocyte retrieval limited to 3 cycles per lifetime; use Z31.84 as primary diagnosis.
Services for AMAB Members
Covered procedures for members assigned male at birth include:
General coverage and medical necessity
Covered when applicable benefit and medical necessity criteria are met (and for self-funded groups with expanded coverage some services such as IVF and gamete freezing are available without an infertility diagnosis).
Specific procedures - stance
Procedures and techniques and the policy stance based on evidence
Coverage conditions
Covered when the following contextual conditions are met:
Applies to codes enumerated as infertility-only.
See specific code groupings for which codes are covered without an infertility diagnosis.
Services provided by egg donation facilitation agencies and fees charged by third-party agencies to locate or contract with a donor are not covered. These agency charges, including associated donor transportation costs, are considered administrative/third-party facilitation fees and are excluded from coverage. Once a donor is identified, clinical services directly related to egg retrieval (including medications and the retrieval procedure) are eligible for coverage per the policy; cryopreservation of donor eggs (retrieval, freezing, storage/monitoring, shipping and thawing) is described separately and may be covered as noted in the cryopreservation section.
Fertility services are excluded for members with a history of prior sterilization unless a clinician review finds clear medical certainty that the prior sterilization is unrelated to the member's present inability to conceive or sustain a pregnancy. Requests for services in this context will undergo clinician review; if the reviewer determines the contractual sterilization exclusion applies, the request will be administratively denied rather than reviewed on medical necessity grounds.
Certain procedures and laboratory cell-processing codes are explicitly listed as non-covered. This includes vasovasostomy/vasovasorrhaphy (CPT 55400). In addition, the policy lists specific cell-processing codes (88240 and 88241) as non-covered. The policy notes that if CPT 55400 is performed for reasons other than reversal of sterilization it may be subject to clinician review.
The Hyaluronan Binding Assay (HBA) for sperm evaluation is identified in the policy as not medically necessary for Commercial Products due to insufficient evidence that it improves net health outcomes. The document further indicates there is no specific CPT code for HBA and suggests use of an unlisted reproductive medicine laboratory code (CPT 89398) when reporting services lacking a specific code.
The policy states that embryo co-culture techniques lack standardized methods and controlled trials demonstrating improved implantation or pregnancy rates; therefore, evidence does not support consistent patient benefit. As a result, embryo co-culture is not supported by the available evidence and is not endorsed as a covered, effective technique in routine IVF practice.
No additional coverage criteria text is required for this placeholder section.
Codes, Limits, and Reimbursement Rules
| Z31.84 | Encounter for fertility preservation procedure |
| 58970 | Follicle puncture for oocyte retrieval, any method |
| 58974 | Embryo transfer, intrauterine |
| 58976 | Gamete, zygote or embryo intrafallopian transfer, any method |
| 76948 | Ultrasonic guidance for aspiration of ova, imaging supervision and interpretation |
| 89250 | Culture of oocyte(s)/embryo(s), less than 4 days |
| 89251 | Culture of oocyte(s)/embryo(s), less than 4 days; with co-culture of oocyte(s) embryo(s) |
| 89253 | Assisted embryo hatching, microtechniques (any method) |
| 89254 | Oocyte identification from follicular fluid |
| 89280 | Assisted oocyte fertilization, microtechnique; less than or equal to 10 oocytes |
| 89281 | Assisted oocyte fertilization, microtechnique; greater than 10 oocytes |
| S4011 | In vitro fertilization; including but not limited to identification and incubation of mature oocytes, fertilization with sperm, incubation of embryo(s), and subsequent visualization for determination |
| Z31.84 | Encounter for fertility preservation procedure |
| 58970 | Follicle puncture for oocyte retrieval, any method |
| 58974 | Embryo transfer, intrauterine |
| 58976 | Gamete, zygote or embryo intrafallopian transfer, any method |
| 76948 | Ultrasonic guidance for aspiration of ova, imaging supervision and interpretation |
| 89250 | Culture of oocyte(s)/embryo(s), less than 4 days |
| 89251 | Culture of oocyte(s)/embryo(s), less than 4 days; with co-culture |
| 89253 | Assisted embryo hatching, microtechniques |
| 89254 | Oocyte identification from follicular fluid |
| 89280 | Assisted oocyte fertilization, microtechnique; ≤10 oocytes |
| 89281 | Assisted oocyte fertilization, microtechnique; >10 oocytes |
| S4011 | In vitro fertilization; identification/incubation of mature oocytes, fertilization and embryo visualization |
| S4017 | Incomplete cycle, treatment cancelled prior to stimulation, case rate |
| S4018 | Frozen embryo transfer procedure cancelled before transfer, case rate |
| S4020 | In vitro fertilization procedure cancelled before aspiration, case rate |
| S4021 | In vitro fertilization procedure cancelled after aspiration, case rate |
| S4022 | Assisted oocyte fertilization, case rate |
| S4042 | Management of ovulation induction, per cycle |
| 58321 | Artificial insemination; intra-cervical |
| 58322 | Artificial insemination; intra-uterine |
| 58323 | Sperm washing for artificial insemination |
| 89260 | Sperm isolation; simple prep for insemination or diagnosis with semen analysis |
| 89261 | Sperm isolation; complex prep for insemination or diagnosis with semen analysis |
| S4035 | Stimulated intrauterine insemination (IUI), case rate |
| 55870 | Electroejaculation |
| 89264 | Sperm identification from testis tissue, fresh or cryopreserved |
| 89335 | Cryopreservation, reproductive tissue, testicular |
| 89354 | Thawing of cryopreserved; reproductive tissue; testicular/ovarian |
| S4023 | Donor egg cycle, incomplete, case rate |
| S4025 | Donor services for IVF, case rate |
| S4026 | Procurement of donor sperm from sperm bank |
| S4028 | Microsurgical epididymal sperm aspiration (MESA) |
| 89257 | Sperm identification from aspiration (other than seminal fluid) |
| 89258 | Cryopreservation; embryo(s) |
| 89259 | Cryopreservation; sperm |
| 89337 | Cryopreservation, mature oocyte(s) |
| 55200 | Vasotomy, cannulization with or without incision of Vas, unilateral or bilateral |
| 58350 | Chromotubation of oviduct, including materials |
| 58750 | Tubotubal anastomosis |
| 89300 | Semen analysis; presence and/or motility of sperm including Huhner test (post coital) |
| 89310 | Semen analysis; motility and count |
| 89320 | Semen analysis; complete (volume, count, motility and differential) |
| 89321 | Semen analysis, presence and/or motility of sperm |
| 89322 | Semen analysis: volume, count, and differential using strict morphologic criteria |
| 89398 | Unlisted reproductive medicine laboratory procedure |
Provider Requirements, Authorization, and Claims Guidance
Obtain prior authorization for SET, MET, and post‑4 IVF cycles
Prior authorization is required for Single Embryo Transfer (SET) IVF cycles for cycle tracking, for Multiple Embryo Transfer (MET) IVF cycles, and for transfers after 4 IVF cycles that did not result in pregnancy and delivery. Authorization is required even when no infertility diagnosis is present for cycle-tracking purposes; if cycle count exceeds four the post-4 documentation requirements (see documentation callout) must be submitted for review.
- SET authorization is for cycle tracking only; no medical criteria needed for SET authorization.
- MET cycles require prior authorization.
- Transfers after 4 unsuccessful IVF cycles require prior authorization and clinical documentation for continued treatment.
No preauthorization required for oocyte retrieval (CPT 58970)
Code 58970 (follicle puncture for oocyte retrieval) is covered and does not require prior authorization; other ART codes may still require authorization or meet medical necessity criteria as specified elsewhere in the policy.
- Submit 58970 without requesting prior authorization.
- Confirm other procedure codes against the policy lists — some are covered without preauthorization while others require meeting medical necessity criteria.
Follow code‑level preauthorization guidance for listed reproductive procedures
The procedural and case‑rate codes explicitly listed as “covered and no preauthorization required” may be billed without prior authorization; services not explicitly listed as no‑preauth remain subject to medical necessity review or prior authorization per the policy.
Document required IUI attempts for AFAB members without sperm exposure before IVF
For AFAB members without exposure to sperm, infertility is determined after three artificial insemination (AI/IUI) cycles; to qualify for IVF, members under 40 must have two documented medicated IUI cycles, while members 40 and older require no medicated IUI cycles.
- Document three failed AI/IUI cycles using donor sperm for AFAB members without sperm exposure.
- Ensure medicated IUI cycle documentation: under 40 = 2 medicated IUI cycles required; 40+ = none required.
No provider action specified
Inventory item present with no summary in planner — no provider action text available in the brief or source; no additional requirement may be asserted.
No provider action specified
Inventory item present with no summary in planner — no provider action text available in the brief or source; no additional requirement may be asserted.
Provide documentation to support continuing IVF after 4 unsuccessful cycles
After four consecutive unsuccessful IVF cycles, the requesting physician must provide documentation of the number and type of prior IVF/IUI attempts, a revised IVF methodology with a literature‑supported predicted success rate, and documentation that the member has been informed of and accepts the predicted success rate.
- Detail number/type of all past IVF and IUI attempts (each embryo transfer counts as one cycle).
- Provide revised IVF methodology and literature‑supported predicted success rate.
- Include documentation the member understands and accepts the predicted success rate.
Use Z31.84 as primary diagnosis on elective fertility preservation claims
For elective fertility preservation claims, use primary diagnosis code Z31.84 (Encounter for fertility preservation procedure) on the claim to ensure correct processing and coordination of benefits.
- Elective fertility preservation is limited to 3 cycles per lifetime; include Z31.84 as the primary diagnosis on all related claims.
Document severe AMAB infertility with two qualifying semen analyses
Severe AMAB infertility must be documented on two separate semen analyses showing one of the policy‑specified thresholds: <10 million total motile sperm/ejaculate (pre‑wash), <3 million total motile sperm (post‑wash), or ≤2% normal forms (Strict Kruger morphology).
- Provide two semen analysis reports meeting at least one of the listed severe infertility criteria.
- Ensure laboratory reports include pre‑wash and post‑wash counts and Kruger morphology as applicable.
Elective fertility preservation — claim coding must use Z31.84
Elective fertility preservation claims must be submitted with primary diagnosis Z31.84; failure to use this diagnosis may result in incorrect processing or coordination of benefits.
- Z31.84 should not be used for members who meet the policy definition of infertility (those members have no lifetime cycle limits).
- For elective preservation (limited to 3 lifetime cycles), always submit Z31.84 as primary diagnosis.
Select correct diagnosis code and include medical necessity documentation
When services are for elective fertility preservation, use Z31.84 as the primary diagnosis; for infertility‑related services use the appropriate infertility diagnosis codes and include supporting medical necessity documentation when codes are covered only if medical necessity criteria are met.
- Elective preservation: primary diagnosis Z31.84 and adhere to the 3‑cycle lifetime limit.
- Infertility treatment: use infertility diagnosis codes; no lifetime cycle limits apply for members meeting infertility definition.
Clinician review required for members with prior sterilization
Requests for fertility services for a member with prior sterilization will undergo clinician review to determine whether the contractual exclusion applies; if inability to conceive may be related to the prior sterilization, the request may result in an administrative denial rather than a medical necessity review.
- Provide clear documentation addressing the relationship (or lack thereof) between prior sterilization and current infertility to support coverage consideration.
- Be aware that a determination that the exclusion applies is an administrative denial.
Risk of administrative denial when prior sterilization may explain infertility
Requests for fertility services for members with previous sterilization may be administratively denied if the inability to conceive is determined to be related to the prior sterilization; such cases are screened under the contractual exclusion.
- Anticipate possible administrative denial when prior sterilization could explain infertility.
- Include documentation that demonstrates medical certainty the sterilization is unrelated, if applicable.
Surrogacy services excluded when surrogate is not a plan member
All services related to surrogate parents are excluded when the surrogate is not a member of this plan; such claims will be denied.
- Do not submit claims for surrogate services unless the surrogate is a plan member.
- Confirm membership status of the surrogate before providing or billing any services.
Failure to use Z31.84 on elective preservation claims may cause denial or processing errors
Claims for elective fertility preservation must use primary diagnosis Z31.84; failure to submit elective preservation services with Z31.84 may lead to incorrect claims processing or denial.
- Elective preservation limited to 3 cycles per lifetime — ensure coding reflects elective status (Z31.84).
- Do not use Z31.84 for members meeting infertility definition.
Background and Scope
Assisted reproductive technologies (ART) encompass fertility treatments in which eggs, sperm or embryos are handled outside the body and include procedures such as in vitro fertilization (IVF), gamete/zygote/embryo transfers, intracytoplasmic sperm injection (ICSI), donor gamete services, and cryopreservation of gametes or reproductive tissue. This policy addresses coverage, medical necessity criteria, prior authorization expectations, and exclusions specific to expanded employer-funded fertility benefits.
Under expanded coverage purchased by self-funded employer clients, some ART services (including IVF cycles and gamete freezing/storage) may be available without a formal infertility diagnosis; otherwise, ART services are covered when the policy-defined medical necessity and infertility criteria are met. Cryopreservation is covered both when medically indicated for infertility or iatrogenic risk and, in limited circumstances, for elective fertility preservation subject to cycle limits and coding requirements.
Cryopreservation for members at risk of iatrogenic infertility (for example, due to surgery, radiation, chemotherapy, or other medical treatments, including certain gender-affirming interventions) is recognized as a covered indication. The policy also describes distinctions between infertility-related services and elective fertility preservation — elective preservation is limited to 3 cycles per lifetime and requires use of primary diagnosis Z31.84 on claims for correct processing.
Key Definitions
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