ICD-10-PCS Code For Nose: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group 3E09 includes procedures performed to introduce substances into the nose. These ICD-10-PCS codes are used for inpatient documentation when a therapeutic or diagnostic substance is administered directly into the nasal passages. Accurate coding within the ICD-10-PCS 3E09 group is essential for proper inpatient reimbursement, as it captures the specific procedure performed and supports clinical documentation accuracy.

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Nose Introduction Procedure Overview

Procedures in this ICD-10-PCS code group involve introduction of therapeutic or diagnostic substances into the nose. These procedures target the physiological systems and anatomical regions related to the nasal passages and mucosa and are coded in the Administration section of ICD-10-PCS. Accurate coding ensures the inpatient record reflects the specific route and site of substance introduction and supports correct inpatient reimbursement. Precise documentation of the nasal introduction procedure and substance used is required to assign the correct ICD-10-PCS code.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
3	Section	Administration
E	Body System	Physiological Systems and Anatomical Regions
0	Operation	Introduction
9	Body Part	Nose

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ICD-10-PCS Code For Nose: Procedure Code Group Overview

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Nose Introduction Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
3	Section	Administration
E	Body System	Physiological Systems and Anatomical Regions
0	Operation	Introduction
9	Body Part	Nose

When to Use

Use a code from this group when a substance is intentionally introduced into the nasal passages for therapeutic or diagnostic purposes during an inpatient encounter. Select the code that matches the substance type and the nasal site documented in the medical record.

ICD-10-PCS Codes

36 rows

ICD-10-PCS Code	Description
3E09305	Introduction of Other Antineoplastic into Nose, Percutaneous Approach
3E0930M	Introduction of Antineoplastic, Monoclonal Antibody, into Nose, Percutaneous Approach
3E09328	Introduction of Oxazolidinones into Nose, Percutaneous Approach
3E09329	Introduction of Other Anti-infective into Nose, Percutaneous Approach
3E0933Z	Introduction of Anti-inflammatory into Nose, Percutaneous Approach
3E0934Z	Introduction of Serum, Toxoid and Vaccine into Nose, Percutaneous Approach
3E093BZ	Introduction of Anesthetic Agent into Nose, Percutaneous Approach
3E093GC	Introduction of Other Therapeutic Substance into Nose, Percutaneous Approach
3E093HZ	Introduction of Radioactive Substance into Nose, Percutaneous Approach
3E093KZ	Introduction of Other Diagnostic Substance into Nose, Percutaneous Approach

Showing 1–10 of 36

Typical Clinical Scenarios

An adult admitted from the emergency department with severe unilateral epistaxis that has failed anterior packing and topical measures; the otolaryngology team performs directed topical application of a vasoconstrictive and hemostatic agent directly into the affected nasal cavity to control bleeding before definitive management. Typical codes: 3E09729, 3E09X29
A pediatric patient hospitalized for recurrent, culture-proven bacterial sinusitis unresponsive to systemic antibiotics who receives instilled topical anti-infective medication into the nasal passages under controlled inpatient observation to deliver high local drug concentrations. Typical codes: 3E09329, 3E09X29
A postoperative inpatient developing a localized nasal mucosal infection at the site of recent endonasal surgery who requires targeted percutaneous instillation of an anti-infective agent into the nose to treat the infection when systemic therapy alone is inadequate. Typical codes: 3E09329, 3E09729

ICD-10-PCS Code For Skin And Mucous Membranes: Procedure Code Group Overview

3E01-SUBCUTANEOUS-TISSUE-INTRODUCTION

ICD-10-PCS Code For Subcutaneous Tissue: Procedure Code Group Overview

3E02-MUSCLE-INTRODUCTION

ICD-10-PCS Code For Muscle: Procedure Code Group Overview

3E03-PERIPHERAL-VEIN-INTRODUCTION

ICD-10-PCS Code For Peripheral Vein: Procedure Code Group Overview

3E04-CENTRAL-VEIN-INTRODUCTION

ICD-10-PCS Code For Central Vein: Procedure Code Group Overview

3E05-PERIPHERAL-ARTERY-INTRODUCTION

ICD-10-PCS Code For Peripheral Artery: Procedure Code Group Overview

3E06-CENTRAL-ARTERY-INTRODUCTION

ICD-10-PCS Code For Central Artery: Procedure Code Group Overview

3E07-CORONARY-ARTERY-INTRODUCTION

ICD-10-PCS Code for Coronary Artery: Procedure Code Group Overview

3E08-HEART-INTRODUCTION

ICD-10-PCS Code For Heart: Procedure Code Group Overview

3E0A-BONE-MARROW-INTRODUCTION

ICD-10-PCS Code For Bone Marrow: Procedure Code Group Overview

Showing 1–10 of 32

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

36 rows

ICD-10-PCS Code	Description
3E09305	Introduction of Other Antineoplastic into Nose, Percutaneous Approach
3E0930M	Introduction of Antineoplastic, Monoclonal Antibody, into Nose, Percutaneous Approach
3E09328	Introduction of Oxazolidinones into Nose, Percutaneous Approach
3E09329	Introduction of Other Anti-infective into Nose, Percutaneous Approach
3E0933Z	Introduction of Anti-inflammatory into Nose, Percutaneous Approach
3E0934Z	Introduction of Serum, Toxoid and Vaccine into Nose, Percutaneous Approach
3E093BZ	Introduction of Anesthetic Agent into Nose, Percutaneous Approach
3E093GC	Introduction of Other Therapeutic Substance into Nose, Percutaneous Approach
3E093HZ	Introduction of Radioactive Substance into Nose, Percutaneous Approach
3E093KZ	Introduction of Other Diagnostic Substance into Nose, Percutaneous Approach

Showing 1–10 of 36

Typical Clinical Scenarios

An adult admitted from the emergency department with severe unilateral epistaxis that has failed anterior packing and topical measures; the otolaryngology team performs directed topical application of a vasoconstrictive and hemostatic agent directly into the affected nasal cavity to control bleeding before definitive management. Typical codes: 3E09729, 3E09X29
A pediatric patient hospitalized for recurrent, culture-proven bacterial sinusitis unresponsive to systemic antibiotics who receives instilled topical anti-infective medication into the nasal passages under controlled inpatient observation to deliver high local drug concentrations. Typical codes: 3E09329, 3E09X29
A postoperative inpatient developing a localized nasal mucosal infection at the site of recent endonasal surgery who requires targeted percutaneous instillation of an anti-infective agent into the nose to treat the infection when systemic therapy alone is inadequate. Typical codes: 3E09329, 3E09729

ICD-10-PCS Code For Skin And Mucous Membranes: Procedure Code Group Overview

3E01-SUBCUTANEOUS-TISSUE-INTRODUCTION

ICD-10-PCS Code For Subcutaneous Tissue: Procedure Code Group Overview

3E02-MUSCLE-INTRODUCTION

ICD-10-PCS Code For Muscle: Procedure Code Group Overview

3E03-PERIPHERAL-VEIN-INTRODUCTION

ICD-10-PCS Code For Peripheral Vein: Procedure Code Group Overview

3E04-CENTRAL-VEIN-INTRODUCTION

ICD-10-PCS Code For Central Vein: Procedure Code Group Overview

3E05-PERIPHERAL-ARTERY-INTRODUCTION

ICD-10-PCS Code For Peripheral Artery: Procedure Code Group Overview

3E06-CENTRAL-ARTERY-INTRODUCTION

ICD-10-PCS Code For Central Artery: Procedure Code Group Overview

3E07-CORONARY-ARTERY-INTRODUCTION

ICD-10-PCS Code for Coronary Artery: Procedure Code Group Overview

3E08-HEART-INTRODUCTION

ICD-10-PCS Code For Heart: Procedure Code Group Overview

3E0A-BONE-MARROW-INTRODUCTION

ICD-10-PCS Code For Bone Marrow: Procedure Code Group Overview

Showing 1–10 of 32

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

ICD-10-PCS Code For Nose: Procedure Code Group Overview

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Nose Introduction Procedure Overview

Code Attributes

OpenPayer

ICD-10-PCS Code For Nose: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Nose: Procedure Code Group Overview policy alerts

Nose Introduction Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

References

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

References

ICD-10-PCS Code For Nose: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Nose: Procedure Code Group Overview policy alerts

Nose Introduction Procedure Overview

Code Attributes

ICD-10-PCS Code For Nose: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Nose: Procedure Code Group Overview policy alerts

Nose Introduction Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS section and operation describe the nose introduction procedures in this group?

What body part and body system are specified for code group 3E09?

How does the approach field vary among the codes listed in 3E09?

Which examples of substances are represented in the 3E09 code set?

Why is accurate coding within ICD-10-PCS group 3E09 important for inpatient records?

References

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS section and operation describe the nose introduction procedures in this group?

What body part and body system are specified for code group 3E09?

How does the approach field vary among the codes listed in 3E09?

Which examples of substances are represented in the 3E09 code set?

Why is accurate coding within ICD-10-PCS group 3E09 important for inpatient records?

References