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    v1.0.28
    OpenPayerPolicy UpdatesReimbursement/Payment PolicyBlue Cross Blue Shield - Alabama advanced lab code…
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    OpenPayer is powered by Trek Health's payer performance platform. Trek continuously ingests, validates, and normalizes Transparency in Coverage data alongside payer policies and other commercial payer data to create a structured payer intelligence foundation. OpenPayer uses this foundation to deliver personalized search results, dynamically generated policy pages, and tailored policy monitoring based on each user's payers, specialties, billing codes, and areas of interest. The same intelligence powers broader payer performance workflows, including reimbursement benchmarking, contract evaluation, payer negotiations, and financial decision-making.

    CurrentBlue Cross Blue Shield - AlabamaPolicy N/A

    Advanced Laboratory CPT Codes

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    This document lists advanced laboratory CPT, HCPCS and related procedure codes that are referenced by the payer for reimbursement/policy purposes; it affects providers billing Blue Cross Blue Shield - Alabama for advanced laboratory testing.

    Policy Summary
    PayerBlue Cross Blue Shield - Alabama
    PolicyAdvanced Laboratory CPT Codes (code list for reimbursement reference)
    Policy CodePolicy N/A
    Change TypeNo material change
    Effective DateN/A
    Next Review DateN/A
    Key ActionUse this compiled listing of advanced laboratory CPT/HCPCS codes for reimbursement reference; no prior authorization or documentation requirements are specified.
    SourceLink
    POLICY UPDATE CHANGES

    No material clinical or coverage changes in this revision.

    ~400code entries or tokens present across the list
    multipleadvanced laboratory-specific codes present
    numerousmolecular pathology/genetic testing codes included
    unspecifiedstate applicability

    Coverage stance

    Coverage stance

    The document presents a code list only; it does not contain explicit coverage criteria, limitations, or clinical indications in the provided text.

    Contains enumerated advanced laboratory CPT/HCPCS codes without attached coverage rules in the visible chunks.

    Advanced laboratory CPT / HCPCS codes

    Advanced laboratory CPT codes (0170U-0213U examples)CPT
    0170UMolecular pathology procedure, not otherwise classified (example)
    0171UMolecular pathology procedure, not otherwise classified (example)
    0172UMolecular pathology procedure, not otherwise classified (example)
    0173UMolecular pathology procedure, not otherwise classified (example)
    0174UMolecular pathology procedure, not otherwise classified (example)
    0175UMolecular pathology procedure, not otherwise classified (example)
    0176UMolecular pathology procedure, not otherwise classified (example)
    0177UMolecular pathology procedure, not otherwise classified (example)
    0178UMolecular pathology procedure, not otherwise classified (example)
    0179UMolecular pathology procedure, not otherwise classified (example)
    1–10 of 39
    1/4
    Advanced laboratory CPT codes (0312U-0331U examples)CPT
    0312UMolecular pathology procedure, not otherwise classified (example)
    0313UMolecular pathology procedure, not otherwise classified (example)
    0315UMolecular pathology procedure, not otherwise classified (example)
    0317UMolecular pathology procedure, not otherwise classified (example)
    0318UMolecular pathology procedure, not otherwise classified (example)
    0319UMolecular pathology procedure, not otherwise classified (example)
    0320UMolecular pathology procedure, not otherwise classified (example)
    0322UMolecular pathology procedure, not otherwise classified (example)
    0323UMolecular pathology procedure, not otherwise classified (example)
    0324UMolecular pathology procedure, not otherwise classified (example)
    1–10 of 17
    1/2
    Advanced laboratory CPT codes (81106-81172 examples)CPT
    81106Cystic fibrosis analysis; common mutation or targeted variant analysis (example)
    81107Cystic fibrosis analysis; extended mutation analysis (example)
    81109Cystic fibrosis full sequence analysis (example)
    81111Digestion, restriction fragment length polymorphism or other analysis (example)
    81120Oncology-related molecular analysis (example)
    81121Oncology-related molecular analysis (example)
    81162Molecular pathology procedure, tiered interpretation (example)
    81163Molecular pathology procedure, tiered interpretation (example)
    81164Molecular pathology procedure, tiered interpretation (example)
    81165Molecular pathology procedure, tiered interpretation (example)
    1–10 of 14
    1/2
    Advanced laboratory CPT codes (81200-81341 examples)CPT
    81200CFTR (cystic fibrosis) gene analysis (example)
    81201CFTR common variant analysis (example)
    81202Genetic testing, example gene (example)
    81203Genetic testing, example gene (example)
    81220Oncology genetic test (example)
    81341Genetic testing, example (example)
    Advanced laboratory CPT codes (81400-81508 examples)CPT
    81400Molecular pathology procedure, not otherwise specified (example)
    81401Molecular pathology procedure, not otherwise specified (example)
    81410Cancer susceptibility panel (example)
    81414Targeted genomic sequence analysis panel (example)
    81415Targeted genomic sequence analysis panel (example)
    81416Targeted genomic sequence analysis panel (example)
    81420Targeted genomic sequence analysis panel (example)
    81422Targeted genomic sequence analysis panel (example)
    81425Targeted genomic sequence analysis panel (example)
    81426Targeted genomic sequence analysis panel (example)
    1–10 of 32
    1/4
    Policy Summary
    PayerBlue Cross Blue Shield - Alabama
    PolicyAdvanced Laboratory CPT Codes (code list for reimbursement reference)
    Policy CodePolicy N/A
    Change TypeNo material change
    Effective DateN/A
    Next Review DateN/A
    Key ActionUse this compiled listing of advanced laboratory CPT/HCPCS codes for reimbursement reference; no prior authorization or documentation requirements are specified.
    SourceLink
    On This Page
    Coverage stanceAdvanced laboratory CPT / HCPCS codesBilling and provider guidanceAdvanced laboratory CPT codes (definitions)

    Billing and provider guidance

    Note

    Code list reference only

    Code list reference only — the following Advanced Laboratory CPT/PLA codes are provided as a reimbursement reference. This section does not establish prior authorization, documentation, or step-therapy requirements. Billing and coverage determinations follow the payer's clinical policy and claims adjudication rules.

    • 0170U
    • 0171U
    • 0172U
    • 0173U
    • 0174U
    • 0175U
    • 0176U
    • 0177U
    • 0178U
    • 0179U
    • 0180U
    • 0181U
    • 0182U
    • 0183U
    • 0184U
    • 0185U
    • 0186U
    • 0187U
    • 0188U
    • 0189U
    • 0190U
    • 0191U
    • 0192U
    • 0193U
    • 0194U
    • 0195U
    • 0196U
    • 0197U
    • 0198U
    • 0199U
    • 0200U
    • 0201U
    • 0203U
    • 0204U
    • 0206U
    • 0207U
    • 0209U
    • 0210U
    • 0213U

    Advanced laboratory CPT codes (definitions)

    Advanced Laboratory CPT Codes list — key definitions and scope
    ScopeCompiled listing of advanced laboratory procedure codes including Category III (0XXXXU series), molecular/genomic (81xxx, 81xxx–81xxx) and complex genomic testing codes (81400–81508) used for reimbursement reference.
    Representative Category III codesExamples shown in the list include 0170U–0213U and 0312U–0331U (Category III/advanced laboratory codes).
    Molecular pathology codesSingle-gene and related molecular pathology CPT codes appear (examples: 81106–81172 series listed in source).
    Genetic sequencing and analysis codesGenetic/molecular sequencing and analysis CPT codes are included (examples: 81200–81341 series referenced in brief).
    Complex genomic testing codesComplex genomic and multigene panel codes are present (examples: 81400–81508 series referenced in brief and source).