CPT code 0186U is a Proprietary Laboratory Analyses (PLA) code reported for the Navigator FUT2 Sequencing test from Grifols Immunohematology Center that sequences specific FUT2 gene regions affecting H blood group antigens and H antigen presence in secretions (eg, saliva); this molecular diagnostic test is a genetic sequencing assay used to assess secretor status relevant to blood transfusion compatibility, organ transplant evaluation, and perinatal/newborn blood‑type considerations, typically performed as a clinical diagnostic laboratory service on blood or saliva specimens in an outpatient or reference laboratory setting.

For related coverage guidance, see recent payer policy updates: RTM Testing of Homocysteine Metabolism-Related Conditions, Multimarker Serum Testing Related to Ovarian Cancer, Genomic Profiling for Selecting Targeted Cancer Therapies.