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    v1.0.28
    OpenPayerBilling CodesDisorders of other endocrine glandsICD-10-CM e28-ovarian-dysfunction
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    ICD-10-CM Code For Ovarian Dysfunction: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group E28 includes disorders of ovarian function such as ovarian hypofunction, ovarian failure, and other ovarian endocrine dysfunctions that affect hormone production and reproductive health. These ICD-10-CM diagnosis codes are used to document clinical scenarios involving menstrual irregularities, infertility related to ovarian dysfunction, and endocrinologic causes of amenorrhea, capturing disease severity and organ-specific involvement. Accurate coding within the ICD-10-CM E28 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM E28: Ovarian Dysfunction Overview

    The diagnoses in this group represent disorders of ovarian function affecting hormone production, menstrual regularity, and fertility. These conditions target the reproductive and endocrine systems and include primary ovarian insufficiency, ovarian hypofunction, and related endocrine disorders. Accurate coding matters for appropriate clinical documentation and reimbursement because it reflects disease severity and guides claim adjudication.

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    When to Use

    Use a code from this group when clinical documentation identifies ovarian endocrine disorders such as primary ovarian insufficiency, ovarian hypofunction, or other specified ovarian dysfunctions contributing to menstrual abnormalities or infertility. Select the most specific code available based on clinical findings, laboratory results, and documented etiology to reflect disease severity and organ involvement.

    ICD-10-CM Codes

    8 rows

    ICD-10-CM CodeDescription
    E28.0Estrogen excess
    E28.1Androgen excess
    E28.2Polycystic ovarian syndrome
    E28.310Symptomatic premature menopause
    E28.319Asymptomatic premature menopause
    E28.39Other primary ovarian failure
    E28.8Other ovarian dysfunction
    E28.9Ovarian dysfunction, unspecified

    DRG Codes

    4 rows

    DRG CodeDescription
    742Uterine and Adnexa Procedures for Non-Malignancy with CC/MCC
    743Uterine and Adnexa Procedures for Non-Malignancy without CC/MCC
    760Menstrual and Other Female Reproductive System Disorders with CC/MCC
    761Menstrual and Other Female Reproductive System Disorders without CC/MCC

    Related Codes

    E20-HYPOPARATHYROIDISM

    ICD-10-CM Code For Hypoparathyroidism: Group Overview

    E21-HYPERPARATHYROIDISM-AND-PARATHYROID-DISORDERS

    ICD-10-CM Code For Hyperparathyroidism And Other Disorders Of Parathyroid Gland: Group Overview

    E22-HYPERFUNCTION-OF-PITUITARY-GLAND

    ICD-10-CM Code For Hyperfunction Of Pituitary Gland: Group Overview

    E23-HYPOFUNCTION-OF-PITUITARY-GLAND

    ICD-10-CM Code For Hypofunction And Other Disorders Of The Pituitary Gland: Group Overview

    E24-CUSHINGS-SYNDROME

    ICD-10-CM Code For Cushing's Syndrome: Group Overview

    E25-ADRENOGENITAL-DISORDERS

    ICD-10-CM Code For Adrenogenital Disorders: Group Overview

    E26-HYPERALDOSTERONISM

    ICD-10-CM Code For Hyperaldosteronism: Group Overview

    E27-OTHER-DISORDERS-OF-ADRENAL-GLAND

    ICD-10-CM Code For Other Disorders Of Adrenal Gland: Group Overview

    E29-TESTICULAR-DYSFUNCTION

    ICD-10-CM Code For Testicular Dysfunction: Group Overview

    E31-POLYGLANDULAR-DYSFUNCTION

    ICD-10-CM Code For Polyglandular Dysfunction: Group Overview

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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