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    v1.0.28
    OpenPayerBilling CodesDisorders of other endocrine glandsICD-10-CM e27-other-disorders-of-adrenal-gland
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    ICD-10-CM Code For Other Disorders Of Adrenal Gland: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group E27 includes disorders of the adrenal gland such as adrenal hypofunction, hyperaldosteronism, adrenal gland dysfunction, and other specified adrenal hormonal imbalances that affect corticosteroid or mineralocorticoid production. These ICD-10-CM diagnosis codes are used to document clinical scenarios including primary or secondary adrenal insufficiency, hyperaldosteronism with hypertension and hypokalemia, and other adrenal hormone disorders that impact fluid, electrolyte, and metabolic status. Accurate coding within the ICD-10-CM E27 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM E27: Other Disorders Of Adrenal Gland Overview

    The ICD-10-CM E27 group captures a range of non-neoplastic disorders affecting the adrenal glands, including conditions that alter adrenal hormone production and electrolyte balance. These diagnoses target the endocrine system and related metabolic disturbances. Accurate coding ensures clinical details are reflected for claims and supports appropriate reimbursement.

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    When to Use

    Use a code from this group when clinical documentation indicates a specific adrenal gland disorder such as primary or secondary adrenal insufficiency, hyperaldosteronism, or other specified adrenal dysfunction. Select the most specific code that reflects the cause, severity, and any associated electrolyte or metabolic abnormalities documented in the medical record.

    ICD-10-CM Codes

    9 rows

    ICD-10-CM CodeDescription
    E27.0Other adrenocortical overactivity
    E27.1Primary adrenocortical insufficiency
    E27.2Addisonian crisis
    E27.3Drug-induced adrenocortical insufficiency
    E27.40Unspecified adrenocortical insufficiency
    E27.49Other adrenocortical insufficiency
    E27.5Adrenomedullary hyperfunction
    E27.8Other specified disorders of adrenal gland
    E27.9Disorder of adrenal gland, unspecified

    DRG Codes

    3 rows

    DRG CodeDescription
    643Endocrine Disorders with MCC
    644Endocrine Disorders with CC
    645Endocrine Disorders without CC/MCC

    Related Codes

    E20-HYPOPARATHYROIDISM

    ICD-10-CM Code For Hypoparathyroidism: Group Overview

    E21-HYPERPARATHYROIDISM-AND-PARATHYROID-DISORDERS

    ICD-10-CM Code For Hyperparathyroidism And Other Disorders Of Parathyroid Gland: Group Overview

    E22-HYPERFUNCTION-OF-PITUITARY-GLAND

    ICD-10-CM Code For Hyperfunction Of Pituitary Gland: Group Overview

    E23-HYPOFUNCTION-OF-PITUITARY-GLAND

    ICD-10-CM Code For Hypofunction And Other Disorders Of The Pituitary Gland: Group Overview

    E24-CUSHINGS-SYNDROME

    ICD-10-CM Code For Cushing's Syndrome: Group Overview

    E25-ADRENOGENITAL-DISORDERS

    ICD-10-CM Code For Adrenogenital Disorders: Group Overview

    E26-HYPERALDOSTERONISM

    ICD-10-CM Code For Hyperaldosteronism: Group Overview

    E28-OVARIAN-DYSFUNCTION

    ICD-10-CM Code For Ovarian Dysfunction: Group Overview

    E29-TESTICULAR-DYSFUNCTION

    ICD-10-CM Code For Testicular Dysfunction: Group Overview

    E31-POLYGLANDULAR-DYSFUNCTION

    ICD-10-CM Code For Polyglandular Dysfunction: Group Overview

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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