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    v1.0.28
    OpenPayerBilling CodesDisorders of other endocrine glandsICD-10-CM e26-hyperaldosteronism
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    ICD-10-CM Code For Hyperaldosteronism: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group E26 includes diagnoses related to excess aldosterone production such as primary and secondary hyperaldosteronism, including conditions caused by adrenal adenomas or bilateral adrenal hyperplasia that lead to hypertension and electrolyte disturbances. These ICD-10-CM diagnosis codes are used to document clinical scenarios involving resistant hypertension, hypokalemia, or adrenal neoplasms and to capture disease severity, organ involvement, and treatment complexity relevant to this group. Accurate coding within the ICD-10-CM E26 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM E26: Hyperaldosteronism Overview

    The ICD-10-CM E26 group represents disorders characterized by excess production of aldosterone, primarily affecting mineralocorticoid balance and blood pressure regulation. These diagnoses target the endocrine system, specifically adrenal gland function and its impact on sodium, potassium, and fluid homeostasis. Accurate coding is important for capturing clinical severity and ensuring appropriate reimbursement and longitudinal patient tracking.

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    When to Use

    Use a code from this group when a clinician documents excess aldosterone production as the cause of hypertension, electrolyte abnormalities, or when an adrenal adenoma or hyperplasia is identified as the underlying etiology. Select the specific code that reflects whether the hyperaldosteronism is primary, secondary, or specified by laterality or associated neoplasm when that level of clinical detail is documented.

    ICD-10-CM Codes

    7 rows

    ICD-10-CM CodeDescription
    E26.01Conn's syndrome
    E26.02Glucocorticoid-remediable aldosteronism
    E26.09Other primary hyperaldosteronism
    E26.1Secondary hyperaldosteronism
    E26.81Bartter's syndrome
    E26.89Other hyperaldosteronism
    E26.9Hyperaldosteronism, unspecified

    DRG Codes

    3 rows

    DRG CodeDescription
    643Endocrine Disorders with MCC
    644Endocrine Disorders with CC
    645Endocrine Disorders without CC/MCC

    Typical Clinical Scenarios

    • A middle-aged adult presents to the emergency department with new-onset severe hypertension, muscle weakness, and frequent headaches. Laboratory evaluation reveals hypokalemia with elevated plasma aldosterone concentration and suppressed plasma renin activity, and adrenal imaging shows a unilateral adrenal mass; the patient is referred for surgical evaluation. A code from this group is assigned to represent primary hyperaldosteronism due to an adrenal adenoma. Typical codes: E26.01, E26.09
    • A patient with long-standing, difficult-to-control hypertension is seen in outpatient endocrinology for evaluation of secondary causes; biochemical testing demonstrates chronically elevated aldosterone levels with low renin but no discrete adrenal lesion on imaging, and the patient is managed medically with mineralocorticoid receptor antagonists. A chronic hyperaldosteronism diagnosis code is recorded to document the ongoing endocrine disorder contributing to resistant hypertension. Typical codes: E26.02, E26.9
    • An inpatient with a known adrenal carcinoma develops metabolic derangements including refractory hypokalemia and volume overload while hospitalized for malignant progression; endocrinology documents aldosterone excess as a complicating endocrine condition affecting inpatient management. A code from this group is used to capture hyperaldosteronism as a comorbidity complicating the current admission. Typical codes: E26.81, E26.89

    Related Codes

    E20-HYPOPARATHYROIDISM

    ICD-10-CM Code For Hypoparathyroidism: Group Overview

    E21-HYPERPARATHYROIDISM-AND-PARATHYROID-DISORDERS

    ICD-10-CM Code For Hyperparathyroidism And Other Disorders Of Parathyroid Gland: Group Overview

    E22-HYPERFUNCTION-OF-PITUITARY-GLAND

    ICD-10-CM Code For Hyperfunction Of Pituitary Gland: Group Overview

    E23-HYPOFUNCTION-OF-PITUITARY-GLAND

    ICD-10-CM Code For Hypofunction And Other Disorders Of The Pituitary Gland: Group Overview

    E24-CUSHINGS-SYNDROME

    ICD-10-CM Code For Cushing's Syndrome: Group Overview

    E25-ADRENOGENITAL-DISORDERS

    ICD-10-CM Code For Adrenogenital Disorders: Group Overview

    E27-OTHER-DISORDERS-OF-ADRENAL-GLAND

    ICD-10-CM Code For Other Disorders Of Adrenal Gland: Group Overview

    E28-OVARIAN-DYSFUNCTION

    ICD-10-CM Code For Ovarian Dysfunction: Group Overview

    E29-TESTICULAR-DYSFUNCTION

    ICD-10-CM Code For Testicular Dysfunction: Group Overview

    E31-POLYGLANDULAR-DYSFUNCTION

    ICD-10-CM Code For Polyglandular Dysfunction: Group Overview

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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