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    v1.0.28
    OpenPayerBilling CodesDisorders of other endocrine glandsICD-10-CM e23-hypofunction-of-pituitary-gland
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    ICD-10-CM Code For Hypofunction And Other Disorders Of The Pituitary Gland: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group E23 includes disorders of the pituitary gland such as hypopituitarism, pituitary dysfunction related to tumors or surgery, and other specified and unspecified pituitary disorders that affect hormone production and regulation. These ICD-10-CM diagnosis codes are used to document clinical scenarios including hormone deficiencies, mass effect from pituitary lesions, postoperative pituitary dysfunction, and multisystem endocrine involvement requiring targeted management. Accurate coding within the ICD-10-CM E23 group supports proper claim adjudication and complete clinical documentation and appropriate reimbursement.

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    ICD-10-CM E23: Hypofunction And Other Disorders Of The Pituitary Gland Overview

    The ICD-10-CM E23 group includes disorders of pituitary gland function, including hypopituitarism, pituitary dysfunction due to tumors, and other specified and unspecified pituitary conditions. These diagnoses affect the endocrine system and can cause multisystem clinical manifestations due to altered hormone production. Accurate coding is important for appropriate claim processing and to reflect the clinical complexity for reimbursement.

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    When to Use

    Use a code from this group when the clinical record documents pituitary hormone deficiency, pituitary mass effect, or postoperative pituitary dysfunction attributable to the pituitary gland. Assign codes that reflect the specific etiology and any associated manifestations when documented in the medical record.

    ICD-10-CM Codes

    6 rows

    ICD-10-CM CodeDescription
    E23.0Hypopituitarism
    E23.1Drug-induced hypopituitarism
    E23.2Diabetes insipidus
    E23.3Hypothalamic dysfunction, not elsewhere classified
    E23.6Other disorders of pituitary gland
    E23.7Disorder of pituitary gland, unspecified

    DRG Codes

    5 rows

    DRG CodeDescription
    643Endocrine Disorders with MCC
    644Endocrine Disorders with CC
    645Endocrine Disorders without CC/MCC
    791Prematurity with Major Problems
    793Full Term Neonate with Major Problems

    Related Codes

    E20-HYPOPARATHYROIDISM

    ICD-10-CM Code For Hypoparathyroidism: Group Overview

    E21-HYPERPARATHYROIDISM-AND-PARATHYROID-DISORDERS

    ICD-10-CM Code For Hyperparathyroidism And Other Disorders Of Parathyroid Gland: Group Overview

    E22-HYPERFUNCTION-OF-PITUITARY-GLAND

    ICD-10-CM Code For Hyperfunction Of Pituitary Gland: Group Overview

    E24-CUSHINGS-SYNDROME

    ICD-10-CM Code For Cushing's Syndrome: Group Overview

    E25-ADRENOGENITAL-DISORDERS

    ICD-10-CM Code For Adrenogenital Disorders: Group Overview

    E26-HYPERALDOSTERONISM

    ICD-10-CM Code For Hyperaldosteronism: Group Overview

    E27-OTHER-DISORDERS-OF-ADRENAL-GLAND

    ICD-10-CM Code For Other Disorders Of Adrenal Gland: Group Overview

    E28-OVARIAN-DYSFUNCTION

    ICD-10-CM Code For Ovarian Dysfunction: Group Overview

    E29-TESTICULAR-DYSFUNCTION

    ICD-10-CM Code For Testicular Dysfunction: Group Overview

    E31-POLYGLANDULAR-DYSFUNCTION

    ICD-10-CM Code For Polyglandular Dysfunction: Group Overview

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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