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    OpenPayerBilling CodesMalignant neoplasms of lymphoid, hematopoietic and related tissueICD-10-CM c94-other-leukemias-of-specified-cell-type
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    ICD-10-CM Code For Other Leukemias Of Specified Cell Type: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group C94 includes malignant leukemias of specified cell types such as monocytic, mast cell, and other defined hematopoietic cell line malignancies that do not fall under more common leukemia categories. These ICD-10-CM diagnosis codes are used to document specific leukemia subtypes, capturing disease distribution, cell-line involvement, and clinical complexity relevant to hematologic malignancy management. Accurate coding within the ICD-10-CM C94 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM C94: Other Leukemias Of Specified Cell Type Overview

    This group represents leukemias originating from specified hematopoietic cell lines other than the more common acute or chronic lymphocytic and myelogenous leukemias. These diagnoses target the hematopoietic and lymphoid system and include malignant proliferations of specific cell types. Accurate coding matters for reimbursement because it ensures claims reflect the precise diagnosis, complexity of care, and supports appropriate payment determination.

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    When to Use

    Use a code from this group when clinical documentation specifies a leukemia arising from a particular cell type that fits the C94 definitions, and when it is not classified elsewhere. These codes apply for reporting the diagnosis on claims and medical records to reflect disease specificity and guide care and reimbursement processes.

    ICD-10-CM Codes

    16 rows

    ICD-10-CM CodeDescription
    C94.00Acute erythroid leukemia, not having achieved remission
    C94.01Acute erythroid leukemia, in remission
    C94.02Acute erythroid leukemia, in relapse
    C94.20Acute megakaryoblastic leukemia not having achieved remission
    C94.21Acute megakaryoblastic leukemia, in remission
    C94.22Acute megakaryoblastic leukemia, in relapse
    C94.30Mast cell leukemia not having achieved remission
    C94.31Mast cell leukemia, in remission
    C94.32Mast cell leukemia, in relapse
    C94.40Acute panmyelosis with myelofibrosis not having achieved remission
    C94.41Acute panmyelosis with myelofibrosis, in remission
    C94.42Acute panmyelosis with myelofibrosis, in relapse
    C94.6Myelodysplastic disease, not elsewhere classified
    C94.80Other specified leukemias not having achieved remission
    C94.81Other specified leukemias, in remission
    C94.82Other specified leukemias, in relapse

    DRG Codes

    16 rows

    DRG CodeDescription
    820Lymphoma and Leukemia with Major O.R. Procedures with MCC
    821Lymphoma and Leukemia with Major O.R. Procedures with CC
    822Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC
    823Lymphoma and Non-Acute Leukemia with Other Procedures with MCC
    824Lymphoma and Non-Acute Leukemia with Other Procedures with CC
    825Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC
    834Acute Leukemia with MCC
    835Acute Leukemia with CC
    836Acute Leukemia without CC/MCC
    837Chemotherapy with Acute Leukemia as Secondary Diagnosis or with High Dose Chemotherapy Agent with MCC
    838Chemotherapy with Acute Leukemia as Secondary Diagnosis with CC or High Dose Chemotherapy Agent
    839Chemotherapy with Acute Leukemia as Secondary Diagnosis without CC/MCC
    840Lymphoma and Non-Acute Leukemia with MCC
    841Lymphoma and Non-Acute Leukemia with CC
    842Lymphoma and Non-Acute Leukemia without CC/MCC
    850Acute Leukemia with Other Procedures

    Typical Clinical Scenarios

    • An adult presents to the emergency department with acute onset fevers, malaise, and rapidly progressive pancytopenia found on complete blood count; peripheral smear and flow cytometry reveal >20% blasts of myeloid origin without maturation and cytogenetics are consistent with acute myelomonocytic differentiation. The patient is admitted for urgent initiation of induction chemotherapy and hematology confirms a diagnosis within this group due to the specified leukemia cell type and acute presentation. Typical codes: C94.00, C94.02
    • A middle-aged patient in hematology clinic with a several-month history of progressive anemia, recurrent infections, and monocytosis undergoes bone marrow biopsy showing chronic myelomonocytic proliferation with dysplasia but not meeting criteria for acute leukemia; the record documents persistent disease requiring disease-modifying therapy and routine oncology follow-up. Because the malignancy is a specified leukemic cell type with chronic or subacute course, a code from this group reflecting the chronic form is assigned. Typical codes: C94.20, C94.22
    • A patient with a prior diagnosis of chemotherapy-treated leukemia presents for evaluation of therapy-related secondary neoplasm and is found to have a new malignant hematopoietic proliferation of a specified cell type confirmed by marrow studies; this is documented as a therapy-related or relapsed process complicating prior treatment. The encounter codes from this group are used to capture the specified secondary or relapsed leukemia as a comorbid neoplastic condition. Typical codes: C94.81, C94.82

    Related Codes

    C81-HODGKIN-LYMPHOMA

    ICD-10-CM Code For Hodgkin Lymphoma: Group Overview

    C82-FOLLICULAR-LYMPHOMA

    ICD-10-CM Code For Follicular Lymphoma: Group Overview

    C83-NON-FOLLICULAR-LYMPHOMA

    ICD-10-CM Code For Non-Follicular Lymphoma: Group Overview

    C84-MATURE-T-NK-CELL-LYMPHOMAS

    ICD-10-CM Code For Mature T/NK-Cell Lymphomas: Group Overview

    C85-OTHER-SPECIFIED-AND-UNSPECIFIED-NON-HODGKIN-LYMPHOMA

    ICD-10-CM Code For Other Specified And Unspecified Types Of Non Hodgkin Lymphoma: Group Overview

    C86-OTHER-SPECIFIED-T-NK-CELL-LYMPHOMA

    ICD-10-CM Code For Other Specified Types Of T NK Cell Lymphoma: Group Overview

    C88-MALIGNANT-IMMUNOPROLIFERATIVE-DISEASES

    ICD-10-CM Code For Malignant Immunoproliferative Diseases And Certain Other B-Cell Lymphomas: Group Overview

    C90-MULTIPLE-MYELOMA-AND-PLASMA-CELL-NEOPLASMS

    ICD-10-CM Code For Multiple Myeloma And Malignant Plasma Cell Neoplasms: Group Overview

    C91-LYMPHOID-LEUKEMIA

    ICD-10-CM Code For Lymphoid Leukemia: Group Overview

    C92-MYELOID-LEUKEMIA

    ICD-10-CM Code For Myeloid Leukemia: Group Overview

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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