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    OpenPayerBilling CodesMalignant neoplasms of lymphoid, hematopoietic and related tissueICD-10-CM c92-myeloid-leukemia
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    ICD-10-CM Code For Myeloid Leukemia: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group C92 includes malignant myeloid leukemias such as acute myeloblastic leukemia and other specified myeloid neoplasms that primarily affect bone marrow and peripheral blood. These ICD-10-CM diagnosis codes are used to document clinical scenarios including disease subtype, treatment status, and complications such as marrow failure or organ involvement. Accurate coding within the ICD-10-CM C92 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM C92: Myeloid Leukemia Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group C92 represents malignant myeloid leukemias affecting hematopoietic cells of the bone marrow and blood. These diagnoses involve uncontrolled proliferation of myeloid lineage cells and can affect systemic functions including blood counts and organ infiltration. Accurate coding is important for clinical documentation and appropriate reimbursement as it informs severity, treatment planning, and claim adjudication.

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    When to Use

    Use codes from this group when documenting a confirmed diagnosis of myeloid leukemia based on clinical, laboratory, and pathological findings. Apply the most specific code available to reflect subtype, disease status, and any associated complications or treatment effects.

    ICD-10-CM Codes

    30 rows

    ICD-10-CM CodeDescription
    C92.00Acute myeloblastic leukemia, not having achieved remission
    C92.01Acute myeloblastic leukemia, in remission
    C92.02Acute myeloblastic leukemia, in relapse
    C92.10Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission
    C92.11Chronic myeloid leukemia, BCR/ABL-positive, in remission
    C92.12Chronic myeloid leukemia, BCR/ABL-positive, in relapse
    C92.20Atypical chronic myeloid leukemia, BCR/ABL-negative, not having achieved remission
    C92.21Atypical chronic myeloid leukemia, BCR/ABL-negative, in remission
    C92.22Atypical chronic myeloid leukemia, BCR/ABL-negative, in relapse
    C92.30Myeloid sarcoma, not having achieved remission
    C92.31Myeloid sarcoma, in remission
    C92.32Myeloid sarcoma, in relapse
    C92.40Acute promyelocytic leukemia, not having achieved remission
    C92.41Acute promyelocytic leukemia, in remission
    C92.42Acute promyelocytic leukemia, in relapse
    C92.50Acute myelomonocytic leukemia, not having achieved remission
    C92.51Acute myelomonocytic leukemia, in remission
    C92.52Acute myelomonocytic leukemia, in relapse
    C92.60Acute myeloid leukemia with 11q23-abnormality not having achieved remission
    C92.61Acute myeloid leukemia with 11q23-abnormality in remission

    Showing 1–20 of 30

    DRG Codes

    16 rows

    DRG CodeDescription
    820Lymphoma and Leukemia with Major O.R. Procedures with MCC
    821Lymphoma and Leukemia with Major O.R. Procedures with CC
    822Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC
    823Lymphoma and Non-Acute Leukemia with Other Procedures with MCC
    824Lymphoma and Non-Acute Leukemia with Other Procedures with CC
    825Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC
    834Acute Leukemia with MCC
    835Acute Leukemia with CC
    836Acute Leukemia without CC/MCC
    837Chemotherapy with Acute Leukemia as Secondary Diagnosis or with High Dose Chemotherapy Agent with MCC
    838Chemotherapy with Acute Leukemia as Secondary Diagnosis with CC or High Dose Chemotherapy Agent
    839Chemotherapy with Acute Leukemia as Secondary Diagnosis without CC/MCC
    840Lymphoma and Non-Acute Leukemia with MCC
    841Lymphoma and Non-Acute Leukemia with CC
    842Lymphoma and Non-Acute Leukemia without CC/MCC
    850Acute Leukemia with Other Procedures

    Typical Clinical Scenarios

    • An adult patient presents to the emergency department with rapidly worsening fatigue, fever, easy bruising, and new-onset petechiae over days; laboratory studies show marked leukocytosis with circulating myeloblasts and thrombocytopenia on peripheral smear, and bone marrow biopsy confirms acute myelogenous leukemia. This acute presentation prompting urgent hematology/oncology admission and initiation of induction chemotherapy is coded to reflect an acute myeloid leukemia diagnosis. Typical codes: C92.00, C92.01
    • A middle-aged patient in outpatient hematology follow-up has a documented history of chronic myelogenous leukemia managed with tyrosine kinase inhibitor therapy; visits focus on monitoring peripheral blood counts, molecular response, and managing chronic therapy side effects. Because this is an ongoing, chronic myeloid neoplasm under surveillance and treatment, a chronic myelogenous leukemia code from the group is assigned to reflect the long-term disease. Typical codes: C92.10, C92.11
    • An older patient with known myelomonocytic leukemia admitted for neutropenic sepsis after recent chemotherapy presenting with fever, hypotension, and positive blood cultures; the hospitalization addresses the infectious complication and destabilization related to the underlying myeloid malignancy. In this setting, the underlying myeloid leukemia diagnosis is coded alongside the infectious complication to capture the comorbid malignant process contributing to the clinical course. Typical codes: C92.20, C92.21

    Related Codes

    C81-HODGKIN-LYMPHOMA

    ICD-10-CM Code For Hodgkin Lymphoma: Group Overview

    C82-FOLLICULAR-LYMPHOMA

    ICD-10-CM Code For Follicular Lymphoma: Group Overview

    C83-NON-FOLLICULAR-LYMPHOMA

    ICD-10-CM Code For Non-Follicular Lymphoma: Group Overview

    C84-MATURE-T-NK-CELL-LYMPHOMAS

    ICD-10-CM Code For Mature T/NK-Cell Lymphomas: Group Overview

    C85-OTHER-SPECIFIED-AND-UNSPECIFIED-NON-HODGKIN-LYMPHOMA

    ICD-10-CM Code For Other Specified And Unspecified Types Of Non Hodgkin Lymphoma: Group Overview

    C86-OTHER-SPECIFIED-T-NK-CELL-LYMPHOMA

    ICD-10-CM Code For Other Specified Types Of T NK Cell Lymphoma: Group Overview

    C88-MALIGNANT-IMMUNOPROLIFERATIVE-DISEASES

    ICD-10-CM Code For Malignant Immunoproliferative Diseases And Certain Other B-Cell Lymphomas: Group Overview

    C90-MULTIPLE-MYELOMA-AND-PLASMA-CELL-NEOPLASMS

    ICD-10-CM Code For Multiple Myeloma And Malignant Plasma Cell Neoplasms: Group Overview

    C91-LYMPHOID-LEUKEMIA

    ICD-10-CM Code For Lymphoid Leukemia: Group Overview

    C93-MONOCYTIC-LEUKEMIA

    ICD-10-CM Code For Monocytic Leukemia: Group Overview

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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