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    v1.0.28
    OpenPayerBilling CodesMalignant neoplasms of lymphoid, hematopoietic and related tissueICD-10-CM c84-mature-t-nk-cell-lymphomas
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    ICD-10-CM Code For Mature T/NK-Cell Lymphomas: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group C84 includes malignant neoplasms of mature T lymphocytes and natural killer cells, covering subtypes such as peripheral T-cell lymphoma, cutaneous T-cell lymphomas, and extranodal natural killer/T-cell lymphoma. These ICD-10-CM diagnosis codes are used to document clinical presentations including nodal or extranodal involvement, skin manifestations, systemic symptoms, and disease aggression or stage. Accurate coding within the ICD-10-CM C84 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM C84: Mature T/NK-Cell Lymphomas Overview

    Mature T-cell and natural killer-cell lymphomas are malignant neoplasms arising from mature T lymphocytes or natural killer cells, often presenting with nodal, extranodal, skin, or systemic involvement. These disorders affect the lymphoid and hematopoietic systems and can range from localized cutaneous disease to aggressive systemic lymphoma. Accurate coding is important for documenting disease extent, supporting appropriate clinical documentation, and ensuring correct reimbursement for oncology care.

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    When to Use

    Assign a code from this group when a clinical diagnosis, pathology report, or oncology consultation documents a mature T-cell or natural killer-cell lymphoma subtype. Use these codes to indicate specific sites of involvement, such as skin, nodes, or extranodal locations, and to reflect disease staging or severity when documented.

    ICD-10-CM Codes

    89 rows

    ICD-10-CM CodeDescription
    C84.00Mycosis fungoides, unspecified site
    C84.01Mycosis fungoides, lymph nodes of head, face, and neck
    C84.02Mycosis fungoides, intrathoracic lymph nodes
    C84.03Mycosis fungoides, intra-abdominal lymph nodes
    C84.04Mycosis fungoides, lymph nodes of axilla and upper limb
    C84.05Mycosis fungoides, lymph nodes of inguinal region and lower limb
    C84.06Mycosis fungoides, intrapelvic lymph nodes
    C84.07Mycosis fungoides, spleen
    C84.08Mycosis fungoides, lymph nodes of multiple sites
    C84.09Mycosis fungoides, extranodal and solid organ sites
    C84.0AMycosis fungoides, in remission
    C84.10Sezary disease, unspecified site
    C84.11Sezary disease, lymph nodes of head, face, and neck
    C84.12Sezary disease, intrathoracic lymph nodes
    C84.13Sezary disease, intra-abdominal lymph nodes
    C84.14Sezary disease, lymph nodes of axilla and upper limb
    C84.15Sezary disease, lymph nodes of inguinal region and lower limb
    C84.16Sezary disease, intrapelvic lymph nodes
    C84.17Sezary disease, spleen
    C84.18Sezary disease, lymph nodes of multiple sites

    Showing 1–20 of 89

    DRG Codes

    15 rows

    DRG CodeDescription
    011Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with MCC
    012Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with CC
    013Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy without CC/MCC
    820Lymphoma and Leukemia with Major O.R. Procedures with MCC
    821Lymphoma and Leukemia with Major O.R. Procedures with CC
    822Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC
    823Lymphoma and Non-Acute Leukemia with Other Procedures with MCC
    824Lymphoma and Non-Acute Leukemia with Other Procedures with CC
    825Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC
    840Lymphoma and Non-Acute Leukemia with MCC
    841Lymphoma and Non-Acute Leukemia with CC
    842Lymphoma and Non-Acute Leukemia without CC/MCC
    974HIV with Major Related Condition with MCC
    975HIV with Major Related Condition with CC
    976HIV with Major Related Condition without CC/MCC

    Typical Clinical Scenarios

    • An elderly patient presents to the emergency department with rapidly enlarging, painful cervical and axillary lymphadenopathy, B symptoms (fever, night sweats, weight loss), and marked fatigue. Tissue biopsy of an involved lymph node demonstrates sheets of atypical mature T-cell lymphocytes with angioinvasion and necrosis consistent with aggressive peripheral T‑cell lymphoma, and staging scans show extranodal involvement; a diagnosis from this group is assigned to capture the specific mature T‑cell neoplasm. Typical codes: C84.10, C84.11
    • A middle-aged adult with a several-month history of persistent pruritic, scaly patches and plaques on the trunk and extremities is evaluated by dermatology; skin biopsy reveals epidermotropic atypical CD4+ T‑cells consistent with cutaneous T‑cell lymphoma, and the patient is started on outpatient skin‑directed therapy with ongoing dermatologic follow‑up. A code from this group is used to indicate a chronic, primarily cutaneous mature T‑cell neoplasm managed in the ambulatory setting. Typical codes: C84.40, C84.41
    • A patient with known systemic mature T‑cell lymphoma undergoing combination chemotherapy is admitted for neutropenic fever and septic complications; the hospitalization documents the underlying malignant T‑cell lymphoma as a comorbidity that affects treatment decisions and prognosis. The admission record assigns a code from this group to identify the patient’s active malignant T/NK‑cell neoplasm contributing to the current clinical course. Typical codes: C84.9A, C84.A0}

    Related Codes

    C81-HODGKIN-LYMPHOMA

    ICD-10-CM Code For Hodgkin Lymphoma: Group Overview

    C82-FOLLICULAR-LYMPHOMA

    ICD-10-CM Code For Follicular Lymphoma: Group Overview

    C83-NON-FOLLICULAR-LYMPHOMA

    ICD-10-CM Code For Non-Follicular Lymphoma: Group Overview

    C85-OTHER-SPECIFIED-AND-UNSPECIFIED-NON-HODGKIN-LYMPHOMA

    ICD-10-CM Code For Other Specified And Unspecified Types Of Non Hodgkin Lymphoma: Group Overview

    C86-OTHER-SPECIFIED-T-NK-CELL-LYMPHOMA

    ICD-10-CM Code For Other Specified Types Of T NK Cell Lymphoma: Group Overview

    C88-MALIGNANT-IMMUNOPROLIFERATIVE-DISEASES

    ICD-10-CM Code For Malignant Immunoproliferative Diseases And Certain Other B-Cell Lymphomas: Group Overview

    C90-MULTIPLE-MYELOMA-AND-PLASMA-CELL-NEOPLASMS

    ICD-10-CM Code For Multiple Myeloma And Malignant Plasma Cell Neoplasms: Group Overview

    C91-LYMPHOID-LEUKEMIA

    ICD-10-CM Code For Lymphoid Leukemia: Group Overview

    C92-MYELOID-LEUKEMIA

    ICD-10-CM Code For Myeloid Leukemia: Group Overview

    C93-MONOCYTIC-LEUKEMIA

    ICD-10-CM Code For Monocytic Leukemia: Group Overview

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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