Adult Cardiac Imaging Guidelines (For Ohio Only)
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Radiology imaging coverage determination guideline governing adult cardiac imaging services for UnitedHealthcare Community Plan members in Ohio; establishes evidence-based use, applicability, and evaluation framework for imaging requests.
No material clinical or coverage changes in this revision.
Coverage Decision Rules and Clinical Criteria
Coverage decision framework
Guideline-level coverage and medical necessity determinations for adult cardiac and related advanced imaging services in Ohio.
Medical necessity general criteria
Covered when imaging is consistent with evidence-based clinical standards and will be used in direct clinical management.
Clinical documentation must be submitted to establish necessity.
Substitution and contrast considerations
Modality substitution and contrast considerations when MRI is contraindicated or renal impairment exists.
Investigational imaging
Investigational and research imaging coverage stance.
Examples and specific investigational codes are listed in condition-specific sections.
3D Rendering — Considered Indications
3D rendering (CPT 76376 or 76377) may be considered when clinical scenarios meet specific conditions and physician concurrent supervision is documented.
Document physician supervision/participation in post-processing; use 76377 when independent workstation post-processing is required and do not use for 2D reformatting.
Image-guided Procedure Coding and Use Constraints
Guidance and imaging supervision codes — appropriate uses and limitations for percutaneous procedures.
MR guidance (77021) is not appropriate for breast or prostate biopsy — use CPT 19085/19086 for MRI-guided breast biopsy; 77013 not for bone ablation (use 20982). Only one unit of guidance code should be reported per encounter.
Percutaneous procedure guidance
Guidance codes for image-directed percutaneous procedures are covered when they represent radiological supervision and interpretation for percutaneous surgical procedures and are billed appropriately.
Unlisted procedure indications
Use of unlisted CT/MR/nuclear codes when no anatomic site-specific code exists or for specific navigation/planning tasks.
Provide documentation justifying use and purpose of unlisted code.
Limited/follow-up CT
Limited or follow-up CT coding and restrictions (CPT 76380).
Not medically necessary for treatment planning and should not be used to capture small additional slices in a diagnostic CT protocol.
Whole-body CT/MR screening
Whole-body CT/MR screening and related whole-body imaging guidance.
Whole-body low-dose skeletal CT is supported for oncologic staging in Multiple Myeloma per ONC-25.
When performed, report using CPT 76498 as no standard CPT/HCPCS exists for WBMRI.
See pediatric/special-population oncology and musculoskeletal guideline references for syndrome-specific guidance.
PET/MRI
PET/MRI coverage — allowed only when specific conditions are met.
When criteria are met, report using CPT 78813 plus CPT 76498.
Definitions and eligibility for cardiac imaging
Definitions and eligibility for cardiac imaging related to chest pain categories and risk modifiers.
Requirements for Exercise Treadmill Test (ETT)
Requirements for Exercise Treadmill Test (ETT) to be considered diagnostic and preferred before imaging when appropriate.
ETT is preferred when medically appropriate; imaging stress testing is used when ETT is not feasible or interpretable.
Medically necessary indications for stress testing with imaging
Medically necessary indications for stress testing with imaging (stress echo, SPECT MPI, PET MPI, or stress cardiac MRI).
AQMBF codes/add-ons apply per coding guidance.
Symptomatic and cannot perform/interpret ETT
Imaging stress testing covered when an individual is symptomatic and cannot perform or has an uninterpretable ETT.
Symptomatic with suspected or known non-obstructive CAD
Stress imaging with AQMBF (PET or MRI) for symptomatic individuals with suspected or known non‑obstructive CAD.
Requires documentation of prior testing and attempts at medical management as applicable.
Symptomatic with inconclusive or abnormal ETT or elevated CAC
Considerations when symptomatic individuals have inconclusive or abnormal ETT or elevated coronary artery calcium (CAC).
Symptomatic with risk factors
Stress imaging coverage for symptomatic individuals with cardiovascular risk factors.
Heart failure or LV systolic dysfunction
Imaging indications for heart failure or left ventricular systolic dysfunction.
Syncope or arrhythmia
Indications for imaging in syncope, arrhythmia, and frequent ventricular ectopy.
Moderate coronary artery stenosis (with or without symptoms)
Imaging when moderate coronary artery stenosis is present or suspected.
Without symptoms (selected indications / preoperative)
Selected asymptomatic/preoperative imaging indications.
Refer to surgical risk tables in guideline.
Initial evaluation indications
Transthoracic echocardiography (TTE) — initial evaluation covered indications.
One repeat TTE is allowed to perform agitated saline/contrast if not done on initial study and initial results indicate need.
Repeat Testing by Interval — Covered Indications
Repeat TTE frequency and interval-based covered indications.
CPT/HCPCS Code Groups and Billing Rules
| C9791 | MRI utilizing Xenon Xe 129 for contrast |
| 19085 | Biopsy, breast, with placement of breast localization device(s), when performed, and imaging of the biopsy specimen, when performed, percutaneous; first lesion, including MR guidance |
| 19086 | Biopsy, breast, with placement of breast localization device(s), when performed, and imaging of the biopsy specimen, when performed, percutaneous; each additional lesion, including MR guidance |
| 75989 | Imaging guidance for percutaneous drainage with placement of catheter (all modalities) |
| 76942 | Ultrasonic guidance for needle placement |
| 77011 | CT guidance for stereotactic localization |
| 77012 | CT guidance for needle placement |
| 77013 | CT guidance for, and monitoring of parenchymal tissue ablation |
| 77021 | MR guidance for needle placement |
| 77022 | MR guidance for, and monitoring of parenchymal tissue ablation |
| C8001 | 3D anatomical segmentation imaging for preoperative planning, data preparation and transmission, obtained from previous diagnostic CT or MR examination of the same anatomy |
| C8931 | Example HCPCS: MRA with dye, Spinal Canal (example of HCPCS usage) |
| S8042 | MRI, low-field (example non-specific HCPCS code to redirect) |
| 77013 | CT guidance for needle electrode placement for tumor ablation (not for bone ablation) |
| 77022 | MR guidance for needle electrode placement for tumor ablation |
| 20982 | CT guidance for bone tumor ablations |
| 76942 | Ultrasound guidance (referenced as another modality guidance code) |
| 77002 | Fluoroscopy guidance (referenced) |
| 77003 | Fluoroscopy guidance (referenced) |
| 76380 | Limited or follow-up CT (used when full diagnostic work is not performed) |
| 76140 | Interpretation of an outside study |
| 76498 | Unlisted magnetic resonance procedure (used to report whole-body MRI) |
| 93350 | Stress echocardiogram with interpretation and report |
| 93351 | Stress echocardiography during exercise or pharmacologic stress with interpretation |
| 78491 | PET MPI, single study (rest or stress) with CT attenuation |
| 78492 | PET MPI, multiple studies (rest and stress) with CT attenuation |
| +78434 | AQMBF PET add-on (list separately) |
| 93306 | Transthoracic echocardiography for transcatheter tricuspid valve replacement follow-up (as listed) |
| 93312 | TEE with 2-D, M-mode, probe placement, image acquisition, interpretation and report |
| 93313 | TEE probe placement only |
| 93314 | TEE image acquisition, interpretation, and report only |
| 93315 | TEE for congenital anomalies with 2-D, M-mode, probe placement, image acquisition, interpretation and report |
| 93316 | TEE for congenital anomalies, probe placement only |
| 93317 | TEE for congenital anomalies, image acquisition, interpretation and report only |
| 93312 | TEE with 2-D, M-mode, probe placement, image acquisition, interpretation and report |
| 93313 | TEE probe placement only |
| 93314 | TEE image acquisition, interpretation, and report only |
| 93315 | TEE for congenital anomalies with 2-D, M-mode, probe placement, image acquisition, interpretation and report |
| 93316 | TEE for congenital anomalies, probe placement only |
| 93317 | TEE for congenital anomalies, image acquisition, interpretation and report only |
| +93320 | Doppler echo, pulsed wave and/or spectral display |
| +93321 | Doppler echo, pulsed wave and/or spectral display, follow-up or limited study |
| +93325 | Doppler echo, color flow velocity mapping |
| 93350 | Echo, transthoracic, with 2D, during rest and exercise stress test and/or pharmacologically induced stress, with report |
| 93351 | Echo, transthoracic, with 2D, during rest and exercise stress test and/or pharmacologically induced stress, with report; including continuous ECG monitoring with physician supervision |
| 93356 | Myocardial strain imaging (speckle tracking longitudinal strain) |
| 93356 | Myocardial strain imaging (speckle tracking longitudinal strain) |
| 78451 | MPI, tomographic (SPECT); single study, at rest or stress |
| 78452 | MPI, tomographic (SPECT); multiple studies, at rest and/or stress |
| 78453 | Myocardial perfusion imaging, planar; single study, at rest or stress |
| 78454 | Myocardial perfusion imaging, planar; multiple studies, at rest and/or stress |
| +0742T | Absolute quantitation of myocardial blood flow (AQMBF), SPECT (add-on) |
| 78481 | First pass study (not to be reported with MPI codes) |
| 78483 | First pass study (alternate code; not to be reported with MPI codes) |
| 78472 | MUGA (planar gated blood pool) (not to be reported with MPI codes) |
| 78473 | MUGA (alternate) (not to be reported with MPI codes) |
| 78494 | SPECT MUGA (not to be reported with MPI codes) |
| 78472 | Cardiac blood pool imaging, gated equilibrium; planar, single study at rest or stress, wall motion study plus ejection fraction |
| 78473 | Cardiac blood pool imaging, gated equilibrium; planar, multiple studies, wall motion study plus ejection fraction, at rest and stress |
| 78481 | Cardiac blood pool imaging (planar), first pass technique; single study, at rest or with stress |
| 78483 | Cardiac blood pool imaging (planar), first pass technique; multiple studies, at rest and with stress |
| 78494 | SPECT MUGA |
| +78496 | Add-on code for RV ejection fraction by first pass technique (list separately with 78472) |
Prior Authorization, Documentation, and Billing Actions
Policy applies to Ohio; unproven/limited services reviewed under Ohio rules
This Medical Policy applies only to the state of Ohio. Any requests for services that are stated as unproven or that have coverage or quantity limits will be evaluated for medical necessity using Ohio Administrative Code 5160-1-01.
CPT code listing does not imply prior authorization
Inclusion of a CPT code in these guidelines does not by itself indicate that the code is subject to management or requires prior authorization; actual prior authorization requirements are determined by payer operations.
Prior authorization may be required for 3D rendering and segmentation
Providers may be required to obtain prior authorization for 3D rendering and related segmentation services even when the base imaging study is not subject to prior authorization.
Single-unit rule for guidance codes; limited CT not for treatment planning
Report only one unit of any radiologic guidance code per individual encounter (date of service); CPT 76380 (limited CT) must not be used for treatment planning.
PET/MRI is allowed only when PET/CT criteria met or PET/CT unavailable
PET/MRI is considered medically necessary only when condition‑specific PET/MRI criteria are met, or when the individual meets PET/CT criteria and PET/CT is unavailable and the provider requests PET/MRI instead.
Prior clinical evaluation and documentation required before advanced cardiac imaging
A pertinent clinical evaluation (history, physical exam, appropriate labs and prior non‑advanced testing) should be available and submitted prior to advanced cardiac imaging except for guideline-supported scheduled surveillance.
- Include recent ECGs, chest x‑ray or prior echocardiography performed after symptom onset or change; obtain most recent prior stress test when relevant.
Prior authorization may be required for stress imaging and AQMBF
Prior authorization may be required, per payer rules, for stress imaging and AQMBF codes; check payer processes for listed CPT and Category III codes.
Allow multiple potential TTE CPT codes on pre-authorization for pediatric cases
For preoperative pediatric transthoracic echocardiography, providers may request multiple potential CPT codes at pre-authorization because the definitive code may depend on findings during the study.
Prior authorization expected for repeat TTE outside stated intervals
Prior authorization may be required when repeat TTE is requested outside the medically necessary intervals or when frequency limits are exceeded; requests should reference the specific interval criteria.
- Examples of intervals: every 3 years for certain mild valvular disease, every 2 years for some cardiomyopathy screening, yearly for specified conditions.
Post-procedure surveillance TTE intervals and prior authorization note
Certain post‑procedure surveillance TTEs are specified as medically necessary at defined intervals (for example after transcatheter tricuspid valve replacement: 1 month, 6 months, 1 year, then annually) and may require prior authorization per payer processes.
- Follow the procedure‑specific surveillance schedule when submitting authorization (e.g., CPT 93306 for listed follow‑up intervals).
Follow related policy references for device/LVAD and specialized prior authorization
Prior authorization requirements for specialized device, LVAD, and other programmatic services are not detailed here; follow related policy references and payer prior authorization processes for those services.
TEE indications and prior authorization for procedural follow‑up
TEE is medically necessary for specific indications listed in the guideline (e.g., suspected endocarditis, intracardiac mass, pre‑procedural LAA closure assessment) and follow-up imaging for LAA closure devices (45 days, additional if peri‑device gap ≥5 mm, and 1 year) may require prior authorization per payer process.
- Document indication and timing (e.g., pre‑procedural, 45‑day post‑LAA closure) when requesting authorization.
Prior authorization may be required for CPT 93356 to confirm indication
CPT 93356 (myocardial strain imaging) is medically necessary only in specified situations (initial LVH evaluation with defined criteria, heart transplant evaluation/surveillance, and cardiotoxic therapy monitoring); prior authorization may be required to confirm documentation meets these indications.
- For initial LVH evaluation, document both unclear etiology of LVH not due to hypertensive heart disease and concern for infiltrative cardiomyopathy.
- For cardiotoxic therapy surveillance, document planned/ongoing cardiotoxic therapy and whether the study is baseline or re‑evaluation.
Authorization and coding implications for nuclear cardiac imaging
Prior authorization and correct coding for nuclear cardiac imaging follow payer rules; do not report first‑pass studies or MUGA/SPECT MUGA codes in conjunction with MPI codes, and be aware some techniques are experimental or obsolete which may affect authorization.
Review prior imaging and clinical course before additional advanced imaging
Review prior imaging and the individual's clinical course before ordering further advanced imaging; repeat studies generally require documentation of progression, recurrence, or that the outcome will change management.
- Obtain and include results of prior diagnostic tests and prior imaging when requesting authorization to avoid denial for duplicate or unnecessary studies.
Do not use CPT 76380 in lieu of full diagnostic CT or for treatment planning
CPT 76380 (limited CT) should not be used as a substitute for full diagnostic CT codes to capture additional slices or for treatment‑planning purposes.
- Use 76380 only for genuinely limited or follow‑up CT work when a full diagnostic code is not performed.
Obtain prior non‑advanced testing before advanced imaging
Obtain prior non‑advanced testing (ECG, chest x‑ray, echocardiogram) and prior stress testing results when possible before advanced cardiac imaging; documentation of these tests should be included with requests.
- Effort should be made to obtain copies of abnormal ECGs to determine whether an ETT would be interpretable.
- Most recent prior stress test and its findings should be provided when relevant.
Stepwise evaluation required before AQMBF in non‑obstructive CAD
For suspected or known non‑obstructive CAD (MINOCA/INOCA/ANOCA), AQMBF (e.g., PET MPI with +78434 or stress cardiac MRI with AQMBF add‑ons) is indicated after prior medical management and/or prior functional testing when symptoms persist.
- Authorization should document prior medical therapy attempted (beta‑blocker, CCB, nitrates, ranolazine, ACE‑I) or prior functional testing results.
- AQMBF is a stepwise escalation after noninvasive/medical management per guideline criteria.
One repeat TTE allowed to perform agitated saline/contrast study
One repeat echocardiogram is medically necessary specifically to perform an agitated saline (bubble) or contrast study if contrast was not administered on the initial study and the initial results indicate the need.
Echocardiography preferred first; use nuclear studies when echo inadequate or discordant
Echocardiography (TTE) is the preferred initial modality to assess left ventricular function; nuclear studies (MUGA, MPI) are appropriate when echocardiography is technically limited or results are discordant and the results will affect management.
- When echocardiography is limited, MUGA or MPI may be authorized if quantitative LVEF measurement will change clinical management (e.g., ICD candidacy, cardiotoxic therapy decisions).
Requests evaluated by evidence‑based criteria; include supporting documentation
Requests will be evaluated using evidence‑based criteria; include supporting documentation demonstrating clinical utility and alignment with guideline indications.
- Imaging requested for data collection or not used in direct clinical management may be considered not medically necessary.
Required clinical documentation to support imaging requests
Submit pertinent clinical documentation since onset or change in symptoms including detailed history, physical exam, appropriate laboratory studies, and prior imaging to establish medical necessity for advanced imaging.
- Include vital signs, height/weight/BMI or habitus description and a clear clinical question describing how imaging will affect management.
- For stress imaging, document prior PCI/CABG history, timing of troponin elevation relative to prior testing, and details of prior ETT/exercise ECG when applicable.
Document physician supervision/participation for 3D rendering
For 3D reconstruction/post‑processing, document the physician's supervision or participation, including the anatomic region to be reconstructed, tissue types/structures to display, planned outputs (images/cine loops), and intended clinical use.
- Documentation of concurrent supervision of the 3D post‑processing is recommended per ACR and required when submitting for prior authorization of 3D codes.
Use CPT 76140 for interpretation of outside studies
When interpreting an outside exam performed at another facility, use CPT 76140 for interpretation of the outside study rather than reporting another diagnostic imaging code for that prior exam.
- If the outside exam is used for comparison with a current exam, include the comparison in the diagnostic code for the current examination.
Pertinent clinical evaluation required before advanced imaging
A pertinent clinical evaluation since the onset or change in symptoms is required prior to advanced imaging; include relevant history, physical exam, labs, and prior test results when submitting requests.
- Effort should be made to obtain copies of abnormal ECGs and the most recent prior stress test.
Required clinical documentation specifics for stress testing
For stress testing requests, documentation should support prior history (e.g., PCI or CABG), timing of troponin elevation relative to testing, exercise ECG details, and symptom description to justify modality selection.
- Document reasons why ETT is not appropriate or is inconclusive, when applicable (e.g., ECG uninterpretable, inability to achieve 85% MPHR).
Include clinical signs, symptoms, or diagnostic test results in requests
Clinical signs, symptoms, or diagnostic test results supporting medical necessity (e.g., chest pain, dyspnea, abnormal ECG, elevated cardiac biomarkers) must be included with imaging requests.
- Include objective findings and how imaging results will affect management decisions.
Document clinical indication for repeat studies
Clinical documentation must support a change in status or the listed indications for repeat studies (for example: new murmur, MI/ACS, worsening heart failure, elevated BNP); absence of such documentation may lead to denial.
- If requesting repeat TTE outside routine intervals, clearly document the clinical trigger or change in status.
TTE study standards and performance requirements
Transthoracic echocardiography (TTE) should be performed as a comprehensive study with multiple acoustic windows, 2D imaging, measurements, and Doppler, and be interpreted by qualified personnel in an accredited facility.
- Ensure study meets comprehensive TTE standards when submitting for authorization or addressing questions about adequacy.
Documentation required to establish medical necessity for TEE
Medical necessity for TEE requires documentation supporting listed indications (for example: inadequate TTE window, suspected endocarditis, intracardiac thrombus, pre‑procedural planning).
- When requesting TEE for device or procedural planning, include relevant prior imaging and clinical rationale.
Study Frequency and Unit Limits
Contrast and Radiation Considerations
Explicit Non-covered and Experimental Services
NOT COVERED — MRI with Xenon Xe 129 (CPT C9791): MRI studies utilizing Xenon Xe 129 (CPT C9791) are considered investigational/experimental and are not covered. Additionally, PET/MRI is generally not medically necessary and should only be considered where condition‑specific criteria or exceptions apply (e.g., when PET/CT criteria are met and PET/CT is unavailable).
NOT COVERED — 3D rendering for routine 2D reformatting: Use of 3D rendering codes (CPT 76376, 76377) to perform or bill for standard 2D reformatting is not appropriate. Two‑dimensional reformatting is included in the base cross‑sectional imaging service and routine 2D reformats should not be billed separately with 3D rendering codes; 3D rendering is reserved for distinct post‑processing that meets the clinical and technical criteria described in the guideline.
NOT COVERED — Guidance codes with open or excisional procedures: Radiologic guidance codes (for example, CPT 77012, 77021, 77013, 77022) are intended to report radiologic supervision and interpretation for percutaneous procedures (needle placement, biopsy, ablation). It is inappropriate to report these guidance codes in conjunction with open, excisional, or incisional surgical procedure codes; such use is not covered.
NOT COVERED — Whole‑body CT / LifeScan for asymptomatic screening: Whole‑body CT or LifeScan protocols (e.g., brain, chest, abdomen, pelvis performed for screening of asymptomatic individuals) are not a covered benefit and are considered not medically necessary due to lack of validated screening benefit and radiation risk concerns. (An exception exists for whole‑body low‑dose skeletal CT when supported for multiple myeloma staging per oncology guidance.)
Guideline Scope and Purpose
BACKGROUND: These guidelines are evidence‑based clinical criteria that evaluate advanced imaging and procedure applications across modalities (MRI, CT, PET, nuclear medicine, ultrasound) for cardiac and related conditions. They define when advanced imaging and post‑processing are medically necessary versus investigational, outline modality substitution and contrast considerations, and establish documentation, coding, and prior authorization expectations to ensure imaging is ordered and reported in ways that will meaningfully affect direct clinical management.
Definitions and Key Terms
Prior Authorization Notes
Document Changes and Review Dates
Policy CSRAD003OH.F (Adult Cardiac Imaging Guidelines) effective in Ohio; applies Ohio Administrative Code 5160-1-01 for evaluation of unproven services and coverage/quantity limits.
Policy last reviewed on 2026-05-07 prior to the 2026-09-01 effective version (V2.0.2026).
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