CPT 78831: SPECT Multi-Region Single-Day Localization
CPT code 78831 represents a single–day SPECT (single-photon emission computed tomography) nuclear imaging study used to localize tumors, inflammatory processes, or the distribution of radiotracers when at least two distinct areas or separate acquisitions are obtained during one session. This code matters nationally because it captures a specific, higher-complexity imaging scenario that can affect utilization patterns, reimbursement flows, and access to advanced diagnostic imaging across outpatient and hospital settings. Key payers discussed include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare.
Readers will find a concise overview of what CPT code 78831 covers, typical clinical indications and settings, and the operational implications for sites that perform SPECT with multi-region or multi-acquisition protocols. The publication outlines payer coverage patterns and benchmarks where available, notes relevant coding and billing considerations, and situates the code within common clinical workflows for nuclear medicine. Data not available in the input is identified explicitly where applicable.
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Billing Code Overview
CPT code 78831 describes a single–day SPECT nuclear imaging study performed to localize a tumor, an inflammatory process, or the distribution of a radioactive tracer. The code covers studies in which at least two distinct areas or separate acquisitions are imaged on the same day (for example, pelvis and knees or separate lung ventilation and perfusion acquisitions). Vascular flow and blood pool imaging are included if performed as part of the same session.
Service type: Nuclear medicine diagnostic imaging (SPECT), multi-region or multi-acquisition, single day
Typical site of service: Outpatient imaging centers, hospital radiology/nuclear medicine departments, and ambulatory surgical centers where SPECT-capable gamma camera systems are available.