CPT code 78492 covers myocardial perfusion PET imaging performed at rest and during exercise- or drug-induced stress, often including gated assessment of ventricular wall motion and ejection fraction. This diagnostic cardiac imaging code is important nationally because PET perfusion studies offer high-resolution assessment of myocardial blood flow and ventricular function, influencing clinical decisions for ischemic heart disease and revascularization planning. The code is used across hospital outpatient departments, ambulatory imaging centers, and specialized cardiac PET facilities.

Key payers discussed include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find an overview of clinical context for myocardial perfusion PET, typical sites of service, and the administrative framing of the service for billing purposes. The publication also summarizes payer coverage patterns, common modifiers encountered in claims, and related administrative considerations.

This content provides clinicians, billing professionals, and policy analysts with a concise reference to understand what CPT code 78492 represents, why it is used, and the operational settings where the service is commonly performed. Data not available in the input is noted where applicable rather than inferred.