CPT/HCPCS code coverage and prior authorization statuses (partial table)
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This document lists CPT/HCPCS codes with associated brand names, brief descriptions, and prior authorization or coverage designations; it applies to CareSource Georgia's coverage determinations for the codes shown in these pages. This is part 1 of a longer policy table and covers immunizations, injections, parenteral nutrition, certain CGM supplies, and various drug/procedure codes appearing in chunks 0–19.
No material clinical or coverage changes in this revision.
Coverage and Prior Authorization Criteria (excerpt)
Partial code coverage table (excerpt)
Coverage and prior authorization statuses shown for listed codes in these chunks.
ALL of the following
Examples (one or more):
- 90378 — listed with Prior Authorization Required in this fragment (vaccine/antibody administration mapping).
See vaccine/antibody administration code entries.
- 90380 — No Prior Authorization Required (RSV/monoclonal antibody seasonal dose mapping).
RSV monoclonal antibody seasonal dose mapping.
- 90381 — No Prior Authorization Required (RSV/monoclonal antibody seasonal dose mapping).
RSV monoclonal antibody seasonal dose mapping.
- 90584 — No Prior Authorization Required (rabies vaccine/administration mapping shown as No Prior Authorization Required).
Vaccine administration entry.
- Note: the table includes many CPT/HCPCS vaccine and administration codes with mixed PA designations; users should consult the specific line item for each code.
Entries are shown in the cited chunks (partial table).
ALL of the following
- 0054A[4], 0064A[4], 0094A[4], 90480 — COVID-19 vaccine administration codes shown as No Prior Authorization Required in these chunks.
See administration code lines in chunk 3.
ALL of the following
- 90683 — marked Not Covered in this fragment (RSV mRNA LNP vaccine entry).
See chunk 5 for Not Covered annotation.
- Multiple 9131x–91317 entries — shown as No Prior Authorization Required for bivalent and related COVID-19 vaccine presentations in this segment.
See chunk 5.
CGM coverage excerpt
CGM-related coverage determinations present in table.
ANY of the following
- A4239 — Non-adjunctive, non-implanted CGM supply allowance (Freestyle Libre/Dexcom) assigned to Pharmacy Benefit and shown as No Prior Authorization Required (Pharmacy Benefit).
Chunk 7 marks A4239 as Pharmacy Benefit / No PA.
See chunk 7 (benefit assignments).
PA and benefit designations for listed J-codes (partial)
Per the excerpt, each J-code is paired with a designation indicating prior authorization status or benefit type and a mapping to a specific drug product.
ANY of the following
- J0139 — mapped to adalimumab (1 mg) and designated as Pharmacy Benefit in this fragment; PA routing may follow pharmacy rules.
Chunk 18 shows J0139 mapped and routed to Pharmacy Benefit.
- J0604 — Cinacalcet (Sensipar) mapped for ESRD-on-dialysis use and shown as No Prior Authorization Required in this fragment; other J060x entries vary by PA/pharmacy benefit.
Chunk 36 shows J0604 as No Prior Authorization Required while other J060x lines differ.
- J0606 — Etelcalcetide (Parsabiv) listed as Prior Authorization Required in this segment.
Chunk 36 shows J0606 = Prior Authorization Required.
See chunks 18, 21, 36 for per-line examples.
Coverage annotations (prior auth / no prior auth / equivalency)
Coverage-related annotations found in these chunks are limited to prior authorization requirements and therapeutic equivalency notes for J-codes.
ALL of the following
Prior authorization examples:
- J0606 — listed as Prior Authorization Required (example from the J06xx group).
Chunk 36 shows J0606 = Prior Authorization Required.
- Therapeutic equivalence notes:: Multiple entries (e.g., daptomycin-related lines) specify 'not therapeutically equivalent' relationships among manufacturer-specific products, indicating they should not be treated as interchangeable for PA/coverage decisions.
See chunk 51 and related entries for 'not therapeutically equivalent' annotations.
Based on chunks 36, 38, 51.
Prior authorization‑based coverage criteria (partial)
Coverage stance indicated by prior authorization flags for specialty and gene therapy injections in this segment.
ALL of the following
- Gene therapy J-codes (examples: J1411–J1414, J1426–J1430) — listed as Prior Authorization Required in this fragment (gene/specialty therapy entries).
Chunk 64 indicates these J14xx entries are Prior Authorization Required.
- Operational note: specialty gene- and cell-therapy entries are consistently flagged for prior authorization in this range—providers should expect PA requirements for these high-cost products.
Chunks 64–65.
See chunk 64 (J1434 = No Prior Authorization Required).
Partial coverage criteria from excerpt
Coverage stance varies by J-code; entries explicitly label whether prior authorization is required or not and sometimes indicate pharmacy benefit routing.
ALL of the following
- J1570–J1576 (Triferic and related mappings) — multiple J157x entries shown as Prior Authorization Required for several Triferic mappings (J1571–J1576).
Chunks 72–73 show J1571–J1576 marked Prior Authorization Required.
- J1580–J1596 — mixed routing: many entries are routed to the Pharmacy Benefit and listed as No Prior Authorization Required (Pharmacy Benefit), while some codes (e.g., J1599) are shown as Prior Authorization Required.
Chunk 73 indicates mixed PA/Pharmacy Benefit for J1580–J1596.
- Insulin pump-related J-codes (J1811–J1815) — generally require Prior Authorization for insulin intended for pump use; several insulin pump entries are explicitly Prior Authorization Required.
Chunk 83 lists J1811–J1815 with PA required for pump-use insulin.
Chunks 72–83.
Per-J-code authorization criteria (excerpt)
Per-code prior authorization stance as listed in these chunks.
ANY of the following
- J2184 — Prior Authorization Required (meropenem mapping, manufacturer-specific non-equivalence noted).
Chunk 90 lists J2184 = Prior Authorization Required.
- J2185 — No Prior Authorization Required (alternative meropenem mapping shown).
Chunk 90 shows J2185 = No Prior Authorization Required.
- J2310 — No Prior Authorization Required (naloxone mapping).
Chunk 95 shows J2310 = No Prior Authorization Required.
- J2506 — Prior Authorization Required (pegfilgrastim / related colony-stimulating agent entries shown elsewhere in the table).
Chunk 111/101 indicate pegfilgrastim lines with PA required; chunk 90 references colony-stimulating agents overall.
Chunks 90, 95, 109.
Per-code coverage stance (partial)
Stated coverage stance per J-code in this section is limited to simple PA requirement flags and benefit assignment (e.g., Pharmacy Benefit).
ANY of the following
- J2941 — marked as Pharmacy Benefit in the listing.
Chunk 111 indicates J2941 = Pharmacy Benefit.
- J3590 — unclassified biologics: multiple high‑cost gene/cell therapies recorded under J3590 are generally shown with Prior Authorization Required in many entries; a specific exception is noted for Avastin when used for eye injections (No Prior Authorization Required).
Chunk 125 documents J3590 PA nuance (Avastin eye injections exception).
- J7030–J7100 — infusion normal saline/dextrose ESRD fluids are marked No Prior Authorization Required in this segment.
Chunk 127 lists these infusion codes as No Prior Authorization Required.
Chunks 125 and 127.
Code-level coverage stances (partial)
Stated coverage stance by HCPCS code in this segment
ANY of the following
- J7030 — No Prior Authorization Required (normal saline infusion; ESRD-on-dialysis use noted).
Chunk 127 shows J7030 = No Prior Authorization Required.
- J7169 — Andexxa (andexanet alfa) listed with Prior Authorization Required annotation in this fragment.
Chunk 129 indicates J7169 listed with Prior Authorization Required in some lines.
- J7311 (and related hyaluronan/implant entries) — Prior Authorization Required for many listed implant/hyaluronan products in this range.
Chunk 136/144 indicate PA for hyaluronan/implant products such as J7311/J7322–J7323.
Chunks 127, 129, 136.
HCPCS coverage mappings (partial)
Coverage stance for specific HCPCS J‑codes as listed in this segment.
ANY of the following
Chunk 156.
Per‑code authorization/coverage nodes (excerpt)
Per‑code coverage/authorization indications present in this segment (examples only; not a complete list):
ANY of the following
- Coverage decision: No Prior Authorization Required (entry marked as Pharmacy Benefit in the line).
Chunk 162 shows J8541 annotation.
- Coverage decision: Prior Authorization Required for some codes in this antiemetic/related group (status varies by specific line).
Chunk 162–164 show mixed PA within the J86xx range.
- Coverage decision: Prior Authorization Required (manufacturer/therapeutic equivalence notes affect PA requirement).
Chunk 168 references J9046 with Prior Authorization Required and therapeutic non-equivalence notes.
Chunks 162–164.
Stated prior authorization stance for sampled codes
Stated coverage/authorization stance for select codes in this extract:
ANY of the following
- Stance: Prior Authorization Required (enfortumab vedotin mapping).
Chunk 180 lists J9249 = Prior Authorization Required.
- Stance: No Prior Authorization Required (example meropenem/methotrexate mapping line showing No PA).
Chunk 180 shows J9255 with No Prior Authorization Required in part of the line.
- Stance: No Prior Authorization Required (tixagevimab and cilgavimab pre-exposure prophylaxis administration mapping).
Chunk 196 indicates M0220 = No Prior Authorization Required.
- Stance: No Prior Authorization Required (home administration mapping noted).
Chunk 196 shows M0221 = No Prior Authorization Required.
- Stance: No Prior Authorization Required (tocilizumab infusion for hospitalized COVID-19 patients — first dose).
Chunk 196/199 show M0249 = No Prior Authorization Required.
- Stance: No Prior Authorization Required (tocilizumab second dose).
Chunk 199 shows M0250 = No Prior Authorization Required.
Chunks 196–199.
Coverage notes for listed injectables
Coverage stance and prior authorization notes for listed injectable products and biosimilars in this section.
ANY of the following
- Multiple M- and Q-codes (examples: M0222, M0223, Q0220, Q0222, Q0249) are indicated as No Prior Authorization Required for the monoclonal antibody/admin infusion lines in these chunks.
Chunks 198, 206 show many M/Q codes with No Prior Authorization Required.
- Some Q-codes (e.g., Q0139 for ferumoxytol-like entries) are explicitly marked Prior Authorization Required — PA varies by product.
Chunk 206 indicates some Q-codes are PA required (e.g., ferumoxytol references).
- Biosimilar Q-code mappings (examples in the Q5100–Q5130 range) show mixed PA statuses: many lines alternate between No Prior Authorization Required and Prior Authorization Required depending on the specific biosimilar and listing.
Chunk 212 documents mixed PA assignments for biosimilar Q-codes.
Chunks 198, 206, 212.
Q-code PA mapping fragment
Q-code biosimilar products
ALL of the following
Mapped Q-code examples (PA variation):
- Q5121–Q5130 — Additional biosimilar mappings (Avsola, Nyvepria, Riabni, Byooviz, Releuko, Stimufend, Cimerli, Vegzelma, Fylnetra) with mixed PA assignments; some lines explicitly show 'No Prior Authorization Required = Prior Authorization Required' indicating variance across listings.
Chunks 217–218 document mixed PA patterns across Q5121–Q5130.
- Rule: each Q-code line in this range maps a Q-code to a biosimilar product and records an explicit PA status or benefit assignment; verify the exact Q-code line when determining authorization needs.
Chunks 216–218.
Chunks 216–218.
S-code coverage fragment
Home infusion and supply coverage indicators
ALL of the following
S-code examples (mix of PA statuses):
- S9325 / S9326 / S9327 / S9328 / S9329 / S9330 / S9331 — Home infusion per‑diem codes for pain, chemotherapy and continuous therapy range between No Prior Authorization Required and Prior Authorization Required depending on intensity/duration (e.g., S9326 and S9330 flagged Prior Authorization Required for continuous services).
Chunks 234–235 show mixed PA for S93xx series.
- Note: each S-code entry includes a short service descriptor and an explicit PA flag in the table—verify the exact S-code and service frequency/duration when assessing authorization requirements.
Chunks 231–235.
Chunks 231–235.
Per-code PA stance (examples)
Per-code authorization stance and brief service descriptor entries
Chunk 247 guidance implied by PA flags for high-cost items.
Code-level coverage annotations
Coverage stance for codes in this segment is expressed directly as annotations next to each code (e.g., 'No Prior Authorization Required', 'Prior Authorization Required', 'Not Covered').
Chunks 255–262 and inventory metadata.
Code Tables and Mappings (excerpt)
| 0054A[4] | Pfizer-BioNTech Covid-19 Vaccine Pre-Diluted administration - Booster |
| 0064A[4] | Moderna Covid-19 Vaccine (Low Dose) administration - Booster |
| 0094A[4] | Moderna Covid-19 Vaccine (Aged 18+) administration - Booster |
| 90480 | Immunization administration by intramuscular injection of SARS-CoV-2 |
| J0134 | Injection, acetaminophen, 10 mg (mapped to acetaminophen injection - Fresenius Kabi); No Prior Authorization Required |
| J0136 | Injection, acetaminophen, 10 mg (mapped to acetaminophen injection - B. Braun); No Prior Authorization Required |
| J0137 | Injection, acetaminophen, 10 mg (mapped to acetaminophen injection - Hikma); No Prior Authorization Required |
| J0138 | Injection, acetaminophen 10 mg and ibuprofen 3 mg; No Prior Authorization Required |
| J0139 | Injection mapped to adalimumab, 1 mg; designated Pharmacy Benefit |
| J0174 | Injection, lecanemab-irmb, 1 mg (Leqembi); listed as Prior Authorization Required |
| J0177 | Injection, aflibercept HD, 1 mg (Eylea HD); listed as Prior Authorization Required |
| J0178 | Injection, aflibercept, 1 mg; Prior Authorization Required |
| J0179 | Injection, brolucizumab-dbll, 1 mg (Beovu); Prior Authorization Required |
| J0650-J0717 (selected examples) | Multiple levothyroxine sodium J-code mappings (J0650-J0717) with therapeutic equivalence notes (selected examples) |
| J0872-J0896 (selected examples) | Daptomycin and related ESA mappings; prior authorization statuses vary by code (selected examples) |
| J1411 | Etranacogene dezaparvovec‑drlb (Hemgenix) per therapeutic dose; Prior Authorization Required noted for gene therapy J-codes |
| J1412 | Valoctocogene roxaparvovec (Roctavian) per ml; Prior Authorization Required indicated |
| J1413 | Delandistrogene moxeparvovec (Elevidys) per therapeutic dose; Prior Authorization Required indicated |
| J1414 | Fidanacogene elaparvovec (Beqvez) per therapeutic dose; listed as Prior Authorization Required |
| J3301-J3315 | Triamcinolone acetonide formulations and related injectable ophthalmic/musculoskeletal products (Xipere, Triesence, Zilretta) with mixed PA requirements |
| J3590 | Unclassified biologic/drug code used for multiple high-cost gene and cell therapies (examples: betibeglogene, elivaldogene, exagamglogene, lovo-cel) with PA required in many entries |
| J7030-J7100 | Unclassified infusion codes for normal saline and dextrose solutions used for ESRD/dialysis (examples: normal saline solution infusions) - No Prior Authorization Required |
| J3590 | Unclassified code usage examples (magnesium sulfate / potassium chloride entries noted) |
| J7030 | Infusion, normal saline solution, 1000 cc — No Prior Authorization Required |
| J7042 | Infusion, 5% dextrose/normal saline (500 ml = 1 unit) — No Prior Authorization Required |
| J7060 | Infusion, 5% dextrose/water (250 cc) — No Prior Authorization Required |
| J9280-J9305 (examples) | Codes mapped to tisotumab vedotin-tftv, tebentafusp-tebn, pemetrexed, pembrolizumab and related agents (examples) |
| M0201-M0250 (examples) | Home vaccine administration and monoclonal antibody infusion/admin codes (COVID-19 related); M0201/M0220–M0250 entries shown with No Prior Authorization Required in many instances |
| M0222 | Bebtelovimab injection (mapped in text); No Prior Authorization Required indicated in entries |
| M0249 | Tocilizumab infusion for hospitalized COVID-19 patients (first dose) — No Prior Authorization Required |
| M0250 | Tocilizumab second dose — No Prior Authorization Required |
| Q0222 | Bebtelovimab 175 mg injection — No Prior Authorization Required |
| Q0220 | Tixagevimab and cilgavimab (Evusheld) for pre-exposure prophylaxis — No Prior Authorization Required |
| Q5101 | Filgrastim-sndz (Zarxio) injection, 1 mcg — biosimilar mapping |
| Q5103 | Infliximab-dyyb (Inflectra) injection, 10 mg — biosimilar mapping |
| Q5105 | Epoetin alfa-epbx (Retacrit) injection, 100 units (ESRD on dialysis) — biosimilar mapping |
| Q5112 | Trastuzumab-dttb (Ontruzant) injection, 10 mg — biosimilar mapping |
| S5501 | Home infusion therapy, catheter care/maintenance, complex — per diem (Prior Authorization Required indicated) |
| S5502 | Home infusion therapy, implanted access device — per diem (Prior Authorization Required indicated) |
| S5550 | Insulin, rapid onset (e.g., lispro/aspart); unit-based supply mapping |
| S5571 | Insulin delivery device, disposable pen (1.5 ml or 3 ml) — No Prior Authorization Required indicated |
| S9329 | Home infusion therapy, chemotherapy infusion — per diem (No Prior Authorization Required indicated for some entries) |
| C9301 | Obecabtagene autoleucel, up to 400 million CD19 CAR-positive viable T cells, per therapeutic dose — Prior Authorization Required |
| J0281 | Injection, aminocaproic acid, 1 gram |
| J9054 | Mapped to product NIKTIMVO / BORUZU; injection mapping shown (Prior Authorization Required) |
| J9161 | Mapped to product NIKTIMVO / LYMPHIR 300MCG; injection mapping shown (Prior Authorization Required) |
| Q5147 | Mapped to product NIKTIMVO / PAVBLU; aflibercept-ayyh biosimilar mapping (Prior Authorization Required) |
| J0601-J0618 | Multiple J06xx codes for oral agents (sevelamer, lanthanum, sucroferric, ferric citrate) with notes indicating No Prior Authorization Required for ESRD on dialysis indications |
| J3373-J3374 | Vancomycin-related codes mapped to various injectable therapeutics; No Prior Authorization Required indicated for some |
Provider Action Highlights and Billing Guidance
Vaccine/antibody codes have mixed PA requirements
Mixed prior authorization statuses are shown for vaccine/antibody administration and product codes — e.g., 90378 is annotated as Prior Authorization Required while 90380, 90381, 90584, 90675 and 91304 are listed as No Prior Authorization Required in the table; confirm PA before billing these codes.
CGM supplies — A4222 requires PA; others use pharmacy benefit or are Not Covered
Adjunctive vs non-adjunctive CGM supplies carry different benefit and PA handling. A4222 (adjunctive CGM supply allowance) is marked Prior Authorization Required; A4239 is assigned to the Pharmacy Benefit and noted as No Prior Authorization Required; A9276–A9278 are listed Not Covered.
High-cost injectables and radiotherapeutics require prior authorization
Multiple high-cost injectables and radiotherapeutics in the listing are designated Prior Authorization Required; obtain PA before administration/billing for these products.
Selected J013x: most are No PA; J0139 mapped to Pharmacy Benefit
Several J013x entries are documented as No Prior Authorization Required; J0139 is routed to the Pharmacy Benefit. Verify per-line status before claim submission.
J017x–J0180 entries now show Prior Authorization Required
Ophthalmologic/neuro J017x–J0180 codes have changed to Prior Authorization Required in the table (example: J0174 for lecanemab/Leqembi is flagged Prior Authorization Required). Confirm PA for these codes prior to service.
- J0174 (lecanemab/Leqembi) — Prior Authorization Required.
- Several adjacent J0177–J0180 entries also transition to Prior Authorization Required; check each J-code's line-level annotation.
J060x series — mixed PA and pharmacy benefit assignments; confirm per-code
J060x entries show mixed PA and benefit designations: some lines indicate Prior Authorization Required or Pharmacy Benefit while others (e.g., J0604) are listed No Prior Authorization Required for ESRD oral mappings. Verify per-code benefit and PA before billing.
Per-code prior authorization indicators vary (example: J0602, J0606)
Per-code examples illustrate varying prior authorization indicators across J-codes (e.g., J0602 annotated 'Prior Authorization Required = Pharmacy Benefit', J0606 'Prior Authorization Required'). Check each listed J-code's annotation prior to submission.
- Use the table entry for the exact PA/benefit mapping (some codes marked 'Prior Authorization Required = Pharmacy Benefit').
- Do not assume uniform PA across the J060x range; follow per-code notes.
Per-J-code PA statuses — some J-codes changed PA status (e.g., J0896/J0898)
This segment shows per-code PA designations where some J-codes are annotated as Prior Authorization Required and others No Prior Authorization Required (examples: J0896/J0898 entries show PA changes). Verify each J-code's PA flag.
Gene therapy/specialty J-codes are Prior Authorization Required
Gene therapy and specialty J-codes (e.g., J1411–J1414, J1426–J1430) are explicitly marked Prior Authorization Required in the table; obtain authorization for these high-cost specialty therapies.
J157x entries (Triferic) require prior authorization
Multiple J157x lines (Triferic and related mappings) are annotated Prior Authorization Required; J1571–J1576 entries indicate PA is required per table.
- J1571–J1576 — Prior Authorization Required for Triferic and mapped immune globulin products.
- Follow the per-code PA requirement when billing Triferic-related injections.
J1580–J1599: mixed PA and pharmacy benefit assignments
Entries for J1580–J1599 show mixed handling: some lines are routed to the Pharmacy Benefit with No Prior Authorization Required, while others (e.g., J1599) are Prior Authorization Required — verify the code-level annotation.
- J1580–J1595 lines are shown with Pharmacy Benefit/No Prior Authorization Required annotations.
- J1599 and select entries remain Prior Authorization Required; check each row before billing.
Insulin-for-pump and certain biologic J-codes require PA
Insulin products for pump use (e.g., J1811–J1814 Fiasp/Lyumjev) and certain biologics (inebilizumab entries) are marked Prior Authorization Required for pump use and biologic administration; secure PA when indicated.
- J1811–J1814 annotated Prior Authorization Required for insulin pump administration (Fiasp, Lyumjev).
- Inebilizumab (J1823 etc.) is listed with Prior Authorization Required annotations.
Labetalol and related entries — mixed PA and equivalence notes
Labetalol-related J-code entries show mixed PA annotations and therapeutic nonequivalence notes; follow the table per-code (some labetalol entries are No Prior Authorization Required while others are Prior Authorization Required).
- Review therapeutic equivalence notes — some manufacturer-specific labetalol listings are 'not therapeutically equivalent'.
- Confirm PA status per exact J-code before billing labetalol/formulation entries.
Sample J-code PA statuses — verify per-line before billing
The table provides many sampled J-code PA statuses (examples: J2021 No Prior Authorization Required; J2184 Prior Authorization Required; J2185 No Prior Authorization Required). Always confirm the code's line-level PA flag before claim submission.
Additional J-codes (e.g., J2310) may be No PA — confirm each code
Additional J-code entries show mixed PA assignments — e.g., naloxone J2310 is listed No Prior Authorization Required; other adjacent J-codes may require PA. Use the table to confirm each code.
- J2310 (naloxone) — No Prior Authorization Required per table.
- Check neighboring J2311–J2329 for per-code PA differences before billing.
Late-chunk J-code entries show mixed PA flags — consult per-code rows
Later J-code entries continue to mix Prior Authorization Required and No Prior Authorization Required flags (examples in J2786–J2800 block); consult the per-code listing for exact PA requirements.
J3590 (unclassified biologics) — PA varies by use; gene/cell therapies usually require PA
Unclassified biologic code J3590 is used for many high-cost gene/cell therapies and shows PA nuance: while many J3590 usages are Prior Authorization Required, specific uses (e.g., Avastin when billed as J3590 for eye injections) are listed No Prior Authorization Required. Confirm intended use before billing.
Multiple codes are explicitly No Prior Authorization Required — use table to confirm
Numerous HCPCS entries in this segment are explicitly labeled No Prior Authorization Required (examples: J7030, J7040, J7042, J7060, J7070, J7165, J0601–J0608, J0615, 90382, 91323). Confirm the list before seeking PA.
- Reference the table rows for exact code lists of No Prior Authorization Required.
- Do not submit unnecessary PAs for codes explicitly marked No Prior Authorization Required.
Coagulation factors and reversal agents require prior authorization
Many coagulation factor and reversal agent codes (examples: J7169 Andexxa, J7170 Hemlibra and other factor products) are marked Prior Authorization Required in the listing; secure PA for these high-cost hematologic agents.
Pharmacy benefit mappings — certain codes handled under pharmacy benefit with PA implications
Some entries are assigned to the Pharmacy Benefit or are annotated 'Prior Authorization Required = Pharmacy Benefit' (examples: portions of the Q- and J- code lists and contraceptive device entries). Confirm benefit routing and PA process for those codes.
- Codes annotated 'Pharmacy Benefit' may require processing via the pharmacy benefit and may have different PA rules (e.g., J7294–J7307, Q5139–Q5144).
- Follow the pharmacy benefit PA workflow where indicated.
Hyaluronan/implant products require prior authorization
Various hyaluronan/implant and ophthalmic/orthopedic injectable product codes (J7311–J7336, J7340–J7345, J7320–J7326 range) are marked Prior Authorization Required; obtain PA prior to administration for these implants/injectables.
COVID-19 monoclonal antibody and tocilizumab M-codes — No PA required per table
COVID-19 monoclonal antibody administration and tocilizumab infusion M-codes (M0220–M0223, M0249–M0250) are documented as No Prior Authorization Required for listed indications (pre-exposure prophylaxis and hospitalized COVID-19 infusion); bill per table without PA for these M-codes.
- M0220/M0221 (tixagevimab/cilgavimab) — No Prior Authorization Required for listed pre-exposure prophylaxis indications.
- M0222–M0223 (bebtelovimab) and M0249–M0250 (tocilizumab for hospitalized COVID-19) — No Prior Authorization Required as annotated.
Q-code MAb and biosimilar PA status is mixed — confirm per-code
Q-code monoclonal antibody and biosimilar entries have mixed PA annotations: many Q-codes (e.g., Q0222, Q0249, Q5116–Q5120 range) are listed No Prior Authorization Required while others (e.g., Q0139, select Q5xxx entries) are Prior Authorization Required; verify the Q-code row before billing.
Q-code biosimilars — PA mappings vary by product and line
Q-code biosimilar mappings show per-line PA changes (examples: Q5119, Q5120, Q5121 etc. show 'No Prior Authorization Required = Prior Authorization Required' toggles). Always use the table row for the final PA designation and map product to code exactly.
S‑codes (home infusion/insulin supplies) — mixed PA; verify per-code
Home infusion and S‑codes (S0197, S5501, S5502, S5517, S5550–S5571, S9325–S9331, S9345–S9353 etc.) include explicit PA designations; some are No Prior Authorization Required (insulin cartridges, certain per-diem codes) while others (continuous/complex home infusion per‑diem codes) require PA — confirm per S-code before billing.
Selected J-/C- drug and biologic codes are Prior Authorization Required
Multiple J- and C- drug/biologic codes are annotated Prior Authorization Required in this segment (examples: C9301–C9304 and J9054/J9161 and other high-cost injectables); secure PA for these therapies before administration.
Numerous HCPCS lines are annotated 'Prior Authorization Required' — obtain PA
The table includes explicit 'Prior Authorization Required' annotations for many HCPCS lines (examples: J9054, J9161, Q5147–Q5152, Q9999, Q2057); check and obtain PA where shown.
- Refer to the specific HCPCS rows annotated 'Prior Authorization Required' when preparing PA requests.
- Do not bill without PA for codes explicitly marked Prior Authorization Required.
Explicit No Prior Authorization Required entries present — follow table
Several entries in this fragment are explicitly marked No Prior Authorization Required (examples include J0601–J0608, J0615, 90382, 91323); do not request PA for these codes unless clinical circumstances require prior review.
Q0224 marked Not Covered — coverage risk
Q0224 is explicitly marked Not Covered in the listing; billing this code risks denial and it should not be submitted for payment under the listed benefit.
- Do not bill Q0224 — marked Not Covered in the table.
- If clinically necessary, request medical policy review prior to billing for potential exception.
Status Keywords and Definitions
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