Summary & Overview
HCPCS S9364: Home Infusion TPN Administrative and Pharmacy Services
HCPCS Level II code S9364 represents a per diem billing code for home infusion total parenteral nutrition (TPN) that bundles administrative services, professional pharmacy services, care coordination, and required supplies and equipment including standard TPN formulas. As home-based complex nutrition support expands, S9364 matters nationally because it captures comprehensive pharmacy and administrative components of TPN care delivered outside institutional settings. Key payers in national analyses include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare.
This publication provides readers with a concise overview of what S9364 covers, how it is used in home infusion programs, and the implications for billing workflows and benefit design. Readers will find benchmark context for per diem TPN administration and pharmacy services, discussion of payer coverage patterns, and relevant policy considerations affecting home infusion reimbursement. The content also outlines what elements are included in the per diem bundle and which services (such as nursing visits or separately billed drugs) are typically billed outside this code. Data not available in the input is clearly noted where applicable.
Billing Code Overview
HCPCS Level II code S9364 describes home infusion therapy for total parenteral nutrition (TPN) provided as a per diem administrative and professional pharmacy service. The code covers administrative services, professional pharmacy services, care coordination, and all necessary supplies and equipment, including standard TPN formula components such as lipids and specialty amino acid formulas. It excludes nursing visits and drugs not part of the standard formula when those are billed separately.
Service type: Home infusion therapy — total parenteral nutrition administrative and pharmacy services (per diem)
Typical site of service: Patient's home (home infusion setting)
Clinical & Coding Specifications
Clinical Context
A 58-year-old patient with short-bowel syndrome and chronic intestinal failure is discharged from an acute-care hospital to receive home infusion therapy for total parenteral nutrition. The patient has a tunneled central venous catheter placed inpatient, a documented plan of care from a gastroenterologist and nutrition support team, and requires daily central-line care, pharmacy compounding and coordination of supply delivery. Home infusion pharmacy performs professional services including TPN formulation (standard amino acid and lipid components included), medication compounding for required electrolytes and micronutrients, administrative services for scheduling nursing visits, and coordination with durable medical equipment for infusion pumps. Nursing visits for catheter care, line access, and infusion management are billed separately. The workflow includes: physician order for home TPN with indication and dosing; home infusion pharmacist review and sterile compounding; supply and pump delivery; home health nurse education and catheter care; daily or per-diem billing for the TPN administrative and pharmacy services under the per-diem code; and periodic clinical reassessment by the prescribing clinician with documentation of weight, intake/output, labs, and catheter status.
Coding Specifications
| Modifier | Description | When to Use |
|---|---|---|
00 | No modifier / default | Typically not appended; use when no other modifier applies |