HCPCS Level II code J2787 identifies riboflavin 5'-phosphate ophthalmic solution in a volume up to 3 ml. This code is used to bill for the ophthalmic pharmaceutical product itself when dispensed or administered in clinical settings. The code matters nationally as new ophthalmic therapeutics and corneal cross-linking adjuncts have increased utilization of specialty ophthalmic agents, making accurate coding important for clinical documentation and payer communications.

Key payers covered in this overview include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find concise benchmarks for payer coverage patterns where available, notes on common billing modifiers, and clinical context describing typical service lines and sites of care. The summary highlights how the code is applied in ambulatory ophthalmology clinics and outpatient specialty centers for procedures or treatments requiring topical riboflavin preparations.

This publication provides a national-level reference for coding staff, revenue cycle teams, and clinical administrators on the purpose and use of J2787, expected service settings, and what elements to verify with payers. Data not available in the input is noted where applicable.