HCPCS Level II code S9331 covers per diem administrative and professional pharmacy services, care coordination, and necessary supplies and equipment for intermittent home chemotherapy infusions (less than 24 hours), with drugs and nursing visits billed separately. This code is important for defining non-drug, non-nursing components of home-based chemotherapy care and influences billing workflows, care coordination models, and payer coverage policies nationally.

Key national payers in typical analyses include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise explanation of the clinical and service context for S9331, how the code separates administrative and professional pharmacy services from drug and nursing charges, and which payers commonly cover or adjudicate these service lines. The publication outlines benchmark topics, potential policy considerations affecting home infusion reimbursement, and the operational implications for billing teams and home infusion providers.

This summary equips revenue leaders, clinical program managers, and policy analysts with a clear understanding of the code’s role in home chemotherapy delivery, expected site-of-service alignment, and the scope of services captured by the per diem code.