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    OpenPayerBilling CodesPoisoning by, adverse effects of and underdosing of drugs, medicaments and biological substancesICD-10-CM t39-nonopioid-analgesic-poisoning
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    ICD-10-CM Code For Poisoning By Nonopioid Analgesics Antipyretics And Antirheumatics: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group T39 includes poisoning, adverse effects, and underdosing of nonopioid analgesics, antipyretics, and antirheumatic medications, covering overdoses, unintended toxic reactions, and insufficient dosing of agents such as acetaminophen and nonsteroidal anti-inflammatory drugs. These ICD-10-CM diagnosis codes are used to document clinical encounters for toxic exposure, adverse drug reactions, or therapeutic failure where organ systems or severity of toxicity must be captured. Accurate coding within the ICD-10-CM T39 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM T39: Poisoning By, Adverse Effect Of And Underdosing Of Nonopioid Analgesics, Antipyretics And Antirheumatics Overview

    This group represents diagnoses for poisoning, adverse effects, and underdosing related to nonopioid analgesics, antipyretics, and antirheumatic medications that primarily affect pain, fever, and inflammatory processes. Codes capture systemic toxicity or complications from these agents, including accidental or intentional overdoses and incorrect dosing. Accurate coding matters for appropriate claims processing and to reflect the clinical complexity that impacts reimbursement.

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    When to Use

    Use a code from this group when a clinical encounter documents toxic exposure, adverse reaction, or underdosing related to nonopioid analgesics, antipyretics, or antirheumatic agents. Select codes that reflect the intent (accidental, intentional self-harm, assault, or undetermined), the clinical effect, and any associated organ system manifestations.

    ICD-10-CM Codes

    162 rows

    ICD-10-CM CodeDescription
    T39.011APoisoning by aspirin, accidental (unintentional), initial encounter
    T39.011DPoisoning by aspirin, accidental (unintentional), subsequent encounter
    T39.011SPoisoning by aspirin, accidental (unintentional), sequela
    T39.012APoisoning by aspirin, intentional self-harm, initial encounter
    T39.012DPoisoning by aspirin, intentional self-harm, subsequent encounter
    T39.012SPoisoning by aspirin, intentional self-harm, sequela
    T39.013APoisoning by aspirin, assault, initial encounter
    T39.013DPoisoning by aspirin, assault, subsequent encounter
    T39.013SPoisoning by aspirin, assault, sequela
    T39.014APoisoning by aspirin, undetermined, initial encounter
    T39.014DPoisoning by aspirin, undetermined, subsequent encounter
    T39.014SPoisoning by aspirin, undetermined, sequela
    T39.015AAdverse effect of aspirin, initial encounter
    T39.015DAdverse effect of aspirin, subsequent encounter
    T39.015SAdverse effect of aspirin, sequela
    T39.016AUnderdosing of aspirin, initial encounter
    T39.016DUnderdosing of aspirin, subsequent encounter
    T39.016SUnderdosing of aspirin, sequela
    T39.091APoisoning by salicylates, accidental (unintentional), initial encounter
    T39.091DPoisoning by salicylates, accidental (unintentional), subsequent encounter

    Showing 1–20 of 162

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    DRG Codes

    9 rows

    DRG CodeDescription
    791Prematurity with Major Problems
    793Full Term Neonate with Major Problems
    917Poisoning and Toxic Effects of Drugs with MCC
    918Poisoning and Toxic Effects of Drugs without MCC
    922Other Injury, Poisoning and Toxic Effect Diagnoses with MCC
    923Other Injury, Poisoning and Toxic Effect Diagnoses without MCC
    949Aftercare with CC/MCC
    950Aftercare without CC/MCC
    951Other Factors Influencing Health Status

    Typical Clinical Scenarios

    • An adult presents to the emergency department after accidentally ingesting an excessive amount of over-the-counter acetaminophen tablets in a single episode with nausea, right upper quadrant pain, and elevated liver enzymes; treatment is initiated for acute toxicity and monitoring for hepatic injury, so an acute poisoning code is assigned for initial encounter. Typical codes: T39.011A, T39.012A
    • An elderly patient on chronic nonprescription nonsteroidal anti-inflammatory drugs (NSAIDs) develops progressive gastrointestinal bleeding and anemia over weeks, requiring hospitalization for transfusion and endoscopy; this represents an adverse effect of a therapeutic nonopioid analgesic and is coded as an adverse effect encounter. Typical codes: T39.091A, T39.092A
    • A pediatric patient is brought to urgent care for inadequate pain control after missing multiple scheduled doses of prescribed nonopioid analgesic for juvenile idiopathic arthritis; documentation of underdosing or missed doses leading to exacerbation of symptoms prompts assignment of an underdosing code. Typical codes: T39.1X5A, T39.2X5A

    Related Codes

    T36-POISONING-BY-SYSTEMIC-ANTIBIOTICS

    ICD-10-CM Code For Poisoning By, Adverse Effect Of And Underdosing Of Systemic Antibiotics: Group Overview

    T37-OTHER-SYSTEMIC-ANTI-INFECTIVES

    ICD-10-CM Code For Poisoning By Other Systemic Anti Infectives And Antiparasitics: Group Overview

    T38-HORMONE-POISONING-AND-UNDERDOSING

    ICD-10-CM Code For Poisoning By Adverse Effect And Underdosing Of Hormones And Their Synthetic Substitutes And Antagonists Not Elsewhere Classified: Group Overview

    T40-POISONING-BY-NARCOTICS-AND-HALLUCINOGENS

    ICD-10-CM Code For Poisoning By Narcotics And Psychodysleptics: Group Overview

    T41-ANESTHETICS-AND-THERAPEUTIC-GASES

    ICD-10-CM Code For Poisoning By Adverse Effect Of And Underdosing Of Anesthetics And Therapeutic Gases: Group Overview

    T42-ANTIEPILEPTIC-SEDATIVE-HYPNOTIC-ANTIPARKINSONISM-DRUGS

    ICD-10-CM Code For Poisoning By Antiepileptic Sedative Hypnotic And Antiparkinsonism Drugs: Group Overview

    T43-POISONING-AND-ADVERSE-EFFECTS-PSYCHOTROPIC

    ICD-10-CM Code For Poisoning By Adverse Effect Of And Underdosing Of Psychotropic Drugs Not Elsewhere Classified: Group Overview

    T44-AUTONOMIC-NERVOUS-SYSTEM-DRUG-EVENTS

    ICD-10-CM Code For Poisoning By Adverse Effect Of And Underdosing Of Drugs Primarily Affecting The Autonomic Nervous System: Group Overview

    T45-PRIMARILY-SYSTEMIC-AND-HEMATOLOGICAL-AGENTS

    ICD-10-CM Code For Poisoning By Adverse Effect And Underdosing Of Primarily Systemic And Hematological Agents Not Elsewhere Classified: Group Overview

    T46-POISONING-CARDIOVASCULAR-AGENTS

    ICD-10-CM Code For Poisoning By Adverse Effect Of And Underdosing Of Agents Primarily Affecting The Cardiovascular System: Group Overview

    Showing 1–10 of 14

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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