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    v1.0.28
    OpenPayerBilling CodesPoisoning by, adverse effects of and underdosing of drugs, medicaments and biological substancesICD-10-CM t38-hormone-poisoning-and-underdosing
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    ICD-10-CM Code For Poisoning By Adverse Effect And Underdosing Of Hormones And Their Synthetic Substitutes And Antagonists Not Elsewhere Classified: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group T38 includes poisoning by, adverse effects of, and underdosing of hormones and their synthetic substitutes and antagonists not classified elsewhere, covering events caused by therapeutic hormones, hormone analogs, and antagonists. These ICD-10-CM diagnosis codes are used to document clinical scenarios such as accidental overdose, adverse drug reactions, and insufficient dosing that impact endocrine function and associated organ systems. Accurate coding within the ICD-10-CM T38 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM T38: Poisoning By, Adverse Effect Of And Underdosing Of Hormones And Their Synthetic Substitutes And Antagonists, Not Elsewhere Classified Overview

    This code group represents poisoning, adverse effects, and underdosing related to hormones and their synthetic substitutes and antagonists that are not classified elsewhere. It targets endocrine-related agents and events affecting hormonal regulation and related organ systems. Accurate coding matters for correct claim processing and reflecting clinical complexity that influences reimbursement and care coordination.

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    When to Use

    Use a code from this group when the clinical record documents poisoning, an adverse effect, or underdosing of hormonal agents or their synthetic substitutes or antagonists not specified in other categories. Select the most specific code reflecting the substance involved and the clinical circumstance, such as overdose, adverse reaction, or insufficient therapeutic dosing.

    ICD-10-CM Codes

    234 rows

    ICD-10-CM CodeDescription
    T38.0X1APoisoning by glucocorticoids and synthetic analogues, accidental (unintentional), initial encounter
    T38.0X1DPoisoning by glucocorticoids and synthetic analogues, accidental (unintentional), subsequent encounter
    T38.0X1SPoisoning by glucocorticoids and synthetic analogues, accidental (unintentional), sequela
    T38.0X2APoisoning by glucocorticoids and synthetic analogues, intentional self-harm, initial encounter
    T38.0X2DPoisoning by glucocorticoids and synthetic analogues, intentional self-harm, subsequent encounter
    T38.0X2SPoisoning by glucocorticoids and synthetic analogues, intentional self-harm, sequela
    T38.0X3APoisoning by glucocorticoids and synthetic analogues, assault, initial encounter
    T38.0X3DPoisoning by glucocorticoids and synthetic analogues, assault, subsequent encounter
    T38.0X3SPoisoning by glucocorticoids and synthetic analogues, assault, sequela
    T38.0X4APoisoning by glucocorticoids and synthetic analogues, undetermined, initial encounter
    T38.0X4DPoisoning by glucocorticoids and synthetic analogues, undetermined, subsequent encounter
    T38.0X4SPoisoning by glucocorticoids and synthetic analogues, undetermined, sequela
    T38.0X5AAdverse effect of glucocorticoids and synthetic analogues, initial encounter
    T38.0X5DAdverse effect of glucocorticoids and synthetic analogues, subsequent encounter
    T38.0X5SAdverse effect of glucocorticoids and synthetic analogues, sequela
    T38.0X6AUnderdosing of glucocorticoids and synthetic analogues, initial encounter
    T38.0X6DUnderdosing of glucocorticoids and synthetic analogues, subsequent encounter
    T38.0X6SUnderdosing of glucocorticoids and synthetic analogues, sequela
    T38.1X1APoisoning by thyroid hormones and substitutes, accidental (unintentional), initial encounter
    T38.1X1DPoisoning by thyroid hormones and substitutes, accidental (unintentional), subsequent encounter

    Showing 1–20 of 234

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    DRG Codes

    9 rows

    DRG CodeDescription
    791Prematurity with Major Problems
    793Full Term Neonate with Major Problems
    917Poisoning and Toxic Effects of Drugs with MCC
    918Poisoning and Toxic Effects of Drugs without MCC
    922Other Injury, Poisoning and Toxic Effect Diagnoses with MCC
    923Other Injury, Poisoning and Toxic Effect Diagnoses without MCC
    949Aftercare with CC/MCC
    950Aftercare without CC/MCC
    951Other Factors Influencing Health Status

    Typical Clinical Scenarios

    • An elderly patient on long‑term levothyroxine replacement misses several doses over weeks and presents to primary care with fatigue, cold intolerance, bradycardia, and worsening cognitive slowing. The clinician documents underdosing of a hormone replacement leading to hypothyroid symptoms and adjusts the medication regimen; a code from this group is assigned to capture the underdosing event. Typical codes: T38.0X6A, T38.0X6D
    • A middle‑aged patient arrives at the emergency department after intentionally taking an excessive amount of a synthetic corticosteroid in a suicide attempt, with acute hypertension, hyperglycemia, and altered mental status requiring monitoring and supportive care. Because this is an acute poisoning/adverse effect from a corticosteroid, an acute encounter code from this group is used to record the adverse drug effect. Typical codes: T38.2X1A, T38.2X1D
    • A reproductive‑age woman on gonadotropin therapy for infertility develops hirsutism and suspected androgenic adverse effects after dose escalation; she is seen in clinic for evaluation of the adverse effects and management of the medication. The visit is coded to indicate an adverse effect of a hormone therapy as a comorbidity complicating her fertility treatment. Typical codes: T38.4X1A, T38.4X1D

    Related Codes

    T36-POISONING-BY-SYSTEMIC-ANTIBIOTICS

    ICD-10-CM Code For Poisoning By, Adverse Effect Of And Underdosing Of Systemic Antibiotics: Group Overview

    T37-OTHER-SYSTEMIC-ANTI-INFECTIVES

    ICD-10-CM Code For Poisoning By Other Systemic Anti Infectives And Antiparasitics: Group Overview

    T39-NONOPIOID-ANALGESIC-POISONING

    ICD-10-CM Code For Poisoning By Nonopioid Analgesics Antipyretics And Antirheumatics: Group Overview

    T40-POISONING-BY-NARCOTICS-AND-HALLUCINOGENS

    ICD-10-CM Code For Poisoning By Narcotics And Psychodysleptics: Group Overview

    T41-ANESTHETICS-AND-THERAPEUTIC-GASES

    ICD-10-CM Code For Poisoning By Adverse Effect Of And Underdosing Of Anesthetics And Therapeutic Gases: Group Overview

    T42-ANTIEPILEPTIC-SEDATIVE-HYPNOTIC-ANTIPARKINSONISM-DRUGS

    ICD-10-CM Code For Poisoning By Antiepileptic Sedative Hypnotic And Antiparkinsonism Drugs: Group Overview

    T43-POISONING-AND-ADVERSE-EFFECTS-PSYCHOTROPIC

    ICD-10-CM Code For Poisoning By Adverse Effect Of And Underdosing Of Psychotropic Drugs Not Elsewhere Classified: Group Overview

    T44-AUTONOMIC-NERVOUS-SYSTEM-DRUG-EVENTS

    ICD-10-CM Code For Poisoning By Adverse Effect Of And Underdosing Of Drugs Primarily Affecting The Autonomic Nervous System: Group Overview

    T45-PRIMARILY-SYSTEMIC-AND-HEMATOLOGICAL-AGENTS

    ICD-10-CM Code For Poisoning By Adverse Effect And Underdosing Of Primarily Systemic And Hematological Agents Not Elsewhere Classified: Group Overview

    T46-POISONING-CARDIOVASCULAR-AGENTS

    ICD-10-CM Code For Poisoning By Adverse Effect Of And Underdosing Of Agents Primarily Affecting The Cardiovascular System: Group Overview

    Showing 1–10 of 14

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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