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    OpenPayerBilling CodesInjuries, Poisonings and Toxic Effects of DrugsDRG 922-other-injury-poisoning-and-toxic-effect-diagnoses-with-mcc
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    Other Injury, Poisoning and Toxic Effect Diagnoses with MCC: Inpatient Reimbursement Overview

    DRG 922 encompasses other injury, poisoning, and toxic effect diagnoses when a Major Complication or Comorbidity is present, reflecting higher clinical severity. This Diagnosis-Related Group matters for inpatient reimbursement because the Major Complication or Comorbidity status increases resource intensity and Medicare payment under the Centers for Medicare & Medicaid Services Inpatient Prospective Payment System.

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    DRG 922 Overview

    DRG 922 covers hospitalizations for a variety of other injury, poisoning, and toxic effect diagnoses when a Major Complication or Comorbidity is present. Cases in this Diagnosis-Related Group often involve significant resource use due to the severity of the primary condition and the impact of the Major Complication or Comorbidity. This DRG matters for Medicare reimbursement because the presence of a Major Complication or Comorbidity increases the relative weight and payment compared with similar cases without a Major Complication or Comorbidity. Accurate capture of diagnoses and documentation directly affects payment under the Inpatient Prospective Payment System administered by the Centers for Medicare & Medicaid Services.

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    Clinical Trials

    • Acute trauma intervention trials focusing on stabilization and early operative versus nonoperative management for complex injuries: these studies enroll patients admitted with diverse injuries, poisonings, or toxic effects who have one or more major complications (MCC) such as hemorrhage, multi-organ failure, or severe neurovascular compromise. They evaluate time-sensitive interventions (for example, damage-control surgery, embolization, airway management protocols, or antidote administration in severe toxic exposures) and compare immediate outcomes like mortality, ICU length of stay, and complication rates. Results inform hospitals and payers about which acute pathways and resource-intensive interventions yield the best survival and shortest high-cost critical care utilization for this heterogeneous DRG population.
    • Comparative effectiveness and care pathway studies examining inpatient multidisciplinary management strategies: these trials compare coordinated care models (orthopedic/trauma surgery with geriatric co-management, toxicology consultation pathways, or integrated critical care bundles) versus usual care for patients with other injury/poisoning diagnoses complicated by MCCs. Populations typically include older adults with fragility-related injuries plus complications, or adults with severe poisoning who develop organ dysfunction; outcomes measured include complication reduction, readmission, functional recovery, and cost per episode. Findings are relevant for providers designing evidence-based care teams and for payers assessing which care pathways reduce downstream costs, length of stay, and post-acute care needs.
    • Post-discharge outcomes and rehabilitation trials assessing long-term functional recovery and resource use after hospitalization for severe injuries or toxic effects with major complications: these prospective cohort studies or randomized trials examine rehabilitation timing, intensity, and community-based interventions (physical therapy, cognitive rehabilitation, substance-use counseling) in patients discharged after an index admission with MCCs. They target measurement of functional status, return to baseline activities, long-term healthcare utilization, and quality-of-life up to 6–12 months post-discharge, which helps health systems and payers plan post-acute services, predict readmission risk, and evaluate cost-effectiveness of investment in rehabilitation and transitional care for this high-risk DRG group.

    Related Codes

    901-WOUND-DEBRIDEMENTS-FOR-INJURIES-WITH-MCC

    Wound Debridements for Injuries with MCC: Inpatient Reimbursement Overview

    902-WOUND-DEBRIDEMENTS-FOR-INJURIES-WITH-CC

    Wound Debridements for Injuries with CC: Inpatient Reimbursement Overview

    903-WOUND-DEBRIDEMENTS-FOR-INJURIES-WITHOUT-CC-MCC

    Wound Debridements for Injuries without CC/MCC: Inpatient Reimbursement Overview

    904-SKIN-GRAFTS-FOR-INJURIES-WITH-CC-MCC

    Skin Grafts for Injuries with CC/MCC: Inpatient Reimbursement Overview

    905-SKIN-GRAFTS-FOR-INJURIES-WITHOUT-CC-MCC

    Skin Grafts for Injuries without CC/MCC: Inpatient Reimbursement Overview

    906-HAND-PROCEDURES-FOR-INJURIES

    Hand Procedures for Injuries: Inpatient Reimbursement Overview

    907-OTHER-O-R-PROCEDURES-FOR-INJURIES-WITH-MCC

    Other O.R. Procedures for Injuries with MCC: Inpatient Reimbursement Overview

    908-OTHER-O-R-PROCEDURES-FOR-INJURIES-WITH-CC

    Other O.R. Procedures for Injuries with CC: Inpatient Reimbursement Overview

    909-OTHER-O-R-PROCEDURES-FOR-INJURIES-WITHOUT-CC-MCC

    Other O.R. Procedures for Injuries without CC/MCC: Inpatient Reimbursement Overview

    913-TRAUMATIC-INJURY-WITH-MCC

    Traumatic Injury with MCC: Inpatient Reimbursement Overview

    Showing 1–10 of 19

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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