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    v1.0.28
    OpenPayerBilling CodesNeoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromesICD-10-CM d37-neoplasm-of-uncertain-behavior-oral-cavity-digestive-organs
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    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Oral Cavity And Digestive Organs: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group D37 includes neoplasms of uncertain behavior affecting the oral cavity and digestive organs, such as lesions with ambiguous histologic features or behavior that is not clearly benign or malignant. These ICD-10-CM diagnosis codes are used to document clinical scenarios where tumor behavior is indeterminate, capturing organ site, diagnostic uncertainty, or the need for further evaluation. Accurate coding within the ICD-10-CM D37 group supports proper claim adjudication and complete clinical documentation and appropriate reimbursement.

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    ICD-10-CM D37: Neoplasm Of Uncertain Behavior Of Oral Cavity And Digestive Organs Overview

    The ICD-10-CM D37 group identifies neoplasms of uncertain or unknown behavior arising in the oral cavity and digestive organs, where histology or clinical course does not clearly indicate benign or malignant status. These codes target tumors that require monitoring, further diagnostic workup, or special consideration in clinical records. Accurate coding ensures clinical records reflect diagnostic uncertainty and supports correct reimbursement and claim processing.

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    When to Use

    Use a code from this group when a documented neoplasm in the oral cavity or digestive tract is explicitly described as of uncertain behavior or when histologic assessment is inconclusive. Apply these codes to reflect diagnostic uncertainty in the record, guide follow-up care coding, and support claims that depend on documented tumor behavior.

    ICD-10-CM Codes

    17 rows

    ICD-10-CM CodeDescription
    D37.01Neoplasm of uncertain behavior of lip
    D37.02Neoplasm of uncertain behavior of tongue
    D37.030Neoplasm of uncertain behavior of the parotid salivary glands
    D37.031Neoplasm of uncertain behavior of the sublingual salivary glands
    D37.032Neoplasm of uncertain behavior of the submandibular salivary glands
    D37.039Neoplasm of uncertain behavior of the major salivary glands, unspecified
    D37.04Neoplasm of uncertain behavior of the minor salivary glands
    D37.05Neoplasm of uncertain behavior of pharynx
    D37.09Neoplasm of uncertain behavior of other specified sites of the oral cavity
    D37.1Neoplasm of uncertain behavior of stomach
    D37.2Neoplasm of uncertain behavior of small intestine
    D37.3Neoplasm of uncertain behavior of appendix
    D37.4Neoplasm of uncertain behavior of colon
    D37.5Neoplasm of uncertain behavior of rectum
    D37.6Neoplasm of uncertain behavior of liver, gallbladder and bile ducts
    D37.8Neoplasm of uncertain behavior of other specified digestive organs
    D37.9Neoplasm of uncertain behavior of digestive organ, unspecified

    DRG Codes

    12 rows

    DRG CodeDescription
    011Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with MCC
    012Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy with CC
    013Tracheostomy for Face, Mouth and Neck Diagnoses or Laryngectomy without CC/MCC
    146Ear, Nose, Mouth and Throat Malignancy with MCC
    147Ear, Nose, Mouth and Throat Malignancy with CC
    148Ear, Nose, Mouth and Throat Malignancy without CC/MCC
    374Digestive Malignancy with MCC
    375Digestive Malignancy with CC
    376Digestive Malignancy without CC/MCC
    435Malignancy of Hepatobiliary System or Pancreas with MCC
    436Malignancy of Hepatobiliary System or Pancreas with CC
    437Malignancy of Hepatobiliary System or Pancreas without CC/MCC

    Typical Clinical Scenarios

    • An adult patient presents to an ENT clinic with a painless, slowly enlarging nonulcerated mass on the lateral border of the tongue discovered during a routine dental examination. Biopsy shows a neoplastic lesion with histology indicating uncertain malignant potential confined to the oral mucosa without clear invasion or metastasis; the patient is scheduled for excisional biopsy and close surveillance. Typical codes: D37.01, D37.02
    • An older patient with a history of chronic GERD undergoes upper endoscopy for progressive dysphagia; an incidental polypoid lesion is found in the distal esophagus and endoscopic biopsy returns atypical glandular proliferation of uncertain behavior. Because the lesion cannot be definitively classified as benign or malignant on initial biopsy, the patient is referred for repeat sampling and possible endoscopic resection, and a code from this group is used for the uncertain-behavior esophageal neoplasm. Typical codes: D37.030, D37.039
    • A middle-aged patient with unexplained iron deficiency anemia is evaluated and colonoscopy identifies a sessile rectosigmoid mucosal lesion with indeterminate histopathology showing cellular atypia but no invasion; the clinical team treats the finding as a neoplasm of uncertain behavior and documents it as a comorbidity affecting management decisions and surveillance intervals. Typical codes: D37.4, D37.5

    Related Codes

    D38-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-MIDDLE-EAR-RESPIRATORY

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Middle Ear And Respiratory And Intrathoracic Organs: Group Overview

    D39-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-FEMALE-GENITAL

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Female Genital Organs: Group Overview

    D40-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-MALE-GENITAL

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Male Genital Organs: Group Overview

    D41-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-URINARY-ORGANS

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Urinary Organs: Group Overview

    D43-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-BRAIN-CNS

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Brain And Central Nervous System: Group Overview

    D44-NEOPLASM-OF-UNCERTAIN-ENDOCRINE-BEHAVIOR

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Endocrine Glands: Group Overview

    D45-POLYCYTHEMIA-VERA

    ICD-10-CM Code For Polycythemia Vera: Group Overview

    D46-MYELODYSPLASTIC-SYNDROMES

    ICD-10-CM Code For Myelodysplastic Syndromes: Group Overview

    D47-OTHER-NEOPLASMS-UNCERTAIN-BEHAVIOR

    ICD-10-CM Code For Other Neoplasms Of Uncertain Behavior Of Lymphoid Hematopoietic And Related Tissue: Group Overview

    D48-NEOPLASM-OF-UNCERTAIN-BEHAVIOR

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Other And Unspecified Sites: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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