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    OpenPayerBilling CodesNeoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromesICD-10-CM d39-neoplasm-of-uncertain-behavior-female-genital
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    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Female Genital Organs: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group D39 includes neoplasms of the female genital organs with uncertain behavior, covering lesions of the ovary, fallopian tube, uterus, cervix, vulva, and vagina that cannot be definitively classified as benign or malignant. These ICD-10-CM diagnosis codes are used to document clinical scenarios where pathology, cytology, or clinical evaluation indicates a neoplasm but the behavior is undetermined, capturing organ involvement and diagnostic uncertainty. Accurate coding within the ICD-10-CM D39 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM D39: Neoplasm Of Uncertain Behavior Of Female Genital Organs Overview

    This group represents neoplasms of the female genital tract whose behavior (benign or malignant) is uncertain at the time of diagnosis, including lesions of the ovary, fallopian tube, uterus, cervix, vulva, and vagina. These codes target the gynecologic organs and are used when pathology or clinical findings do not confirm benign or malignant behavior. Accurate coding is important for complete clinical records and supports appropriate reimbursement through correct claim documentation.

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    When to Use

    Use a code from this group when clinical notes, pathology reports, or cytology indicate a neoplasm of a female genital organ but do not establish benign or malignant behavior. These codes apply during initial workup, indeterminate pathology, or when the clinician documents uncertainty about tumor behavior.

    ICD-10-CM Codes

    7 rows

    ICD-10-CM CodeDescription
    D39.0Neoplasm of uncertain behavior of uterus
    D39.10Neoplasm of uncertain behavior of unspecified ovary
    D39.11Neoplasm of uncertain behavior of right ovary
    D39.12Neoplasm of uncertain behavior of left ovary
    D39.2Neoplasm of uncertain behavior of placenta
    D39.8Neoplasm of uncertain behavior of other specified female genital organs
    D39.9Neoplasm of uncertain behavior of female genital organ, unspecified

    DRG Codes

    9 rows

    DRG CodeDescription
    736Uterine and Adnexa Procedures for Ovarian or Adnexal Malignancy with MCC
    737Uterine and Adnexa Procedures for Ovarian or Adnexal Malignancy with CC
    738Uterine and Adnexa Procedures for Ovarian or Adnexal Malignancy without CC/MCC
    739Uterine and Adnexa Procedures for Non-Ovarian and Non-Adnexal Malignancy with MCC
    740Uterine and Adnexa Procedures for Non-Ovarian and Non-Adnexal Malignancy with CC
    741Uterine and Adnexa Procedures for Non-Ovarian and Non-Adnexal Malignancy without CC/MCC
    754Malignancy, Female Reproductive System with MCC
    755Malignancy, Female Reproductive System with CC
    756Malignancy, Female Reproductive System without CC/MCC

    Typical Clinical Scenarios

    • A 32-year-old woman presents to gynecologic outpatient clinic with several months of intermenstrual spotting and a palpable adnexal mass on bimanual exam; transvaginal ultrasound shows a unilateral complex ovarian lesion that is indeterminate for malignancy, and surgical excision with histopathology returns a borderline (tumor of uncertain malignant potential) ovarian neoplasm. A diagnosis from this group is assigned because the pathology reports neoplasm of uncertain behavior of the ovary rather than benign or malignant classification. Typical codes: D39.1, D39.11.
    • A 48-year-old perimenopausal patient is seen urgently for abnormal uterine bleeding and pelvic pain; endometrial biopsy demonstrates a glandular proliferation suspicious but not diagnostic for carcinoma, described as an endometrial neoplasm of uncertain malignant potential, and the patient is scheduled for definitive surgical management. The uncertain histologic behavior of the endometrial lesion prompts assignment of a code from this group. Typical codes: D39.0.
    • A 60-year-old woman with a history of hysterectomy for persistent pelvic mass presents for surveillance after prior pathology reported a neoplasm of uncertain behavior of the fallopian tube following salpingectomy; she has intermittent pelvic fullness but no systemic symptoms and is followed with serial imaging and exam. Because the prior surgical pathology described uncertain behavior of a female genital tract neoplasm originating in the fallopian tube, a code from this group is used to document the prior neoplasm and guide follow-up. Typical codes: D39.2, D39.9.

    Related Codes

    D37-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-ORAL-CAVITY-DIGESTIVE-ORGANS

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Oral Cavity And Digestive Organs: Group Overview

    D38-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-MIDDLE-EAR-RESPIRATORY

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Middle Ear And Respiratory And Intrathoracic Organs: Group Overview

    D40-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-MALE-GENITAL

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Male Genital Organs: Group Overview

    D41-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-URINARY-ORGANS

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Urinary Organs: Group Overview

    D43-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-BRAIN-CNS

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Brain And Central Nervous System: Group Overview

    D44-NEOPLASM-OF-UNCERTAIN-ENDOCRINE-BEHAVIOR

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Endocrine Glands: Group Overview

    D45-POLYCYTHEMIA-VERA

    ICD-10-CM Code For Polycythemia Vera: Group Overview

    D46-MYELODYSPLASTIC-SYNDROMES

    ICD-10-CM Code For Myelodysplastic Syndromes: Group Overview

    D47-OTHER-NEOPLASMS-UNCERTAIN-BEHAVIOR

    ICD-10-CM Code For Other Neoplasms Of Uncertain Behavior Of Lymphoid Hematopoietic And Related Tissue: Group Overview

    D48-NEOPLASM-OF-UNCERTAIN-BEHAVIOR

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Other And Unspecified Sites: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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