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    v1.0.28
    OpenPayerBilling CodesNeoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromesICD-10-CM d41-neoplasm-of-uncertain-behavior-urinary-organs
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    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Urinary Organs: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group D41 includes neoplasms of uncertain behavior of urinary organs, covering lesions in structures such as the kidney, ureter, bladder, and other urinary tract sites where malignant potential is not established. These ICD-10-CM diagnosis codes are used to document clinical encounters for observation, biopsy, or follow-up of lesions with indeterminate pathology, capturing organ involvement and diagnostic complexity. Accurate coding within the ICD-10-CM D41 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM D41: Neoplasm Of Uncertain Behavior Of Urinary Organs Overview

    The ICD-10-CM D41 group represents neoplasms of uncertain behavior arising in urinary organs such as the kidney, ureter, bladder, and other urinary structures. These diagnoses indicate lesions for which pathologic behavior is not clearly benign or malignant and often require surveillance or further diagnostic workup. Accurate coding affects clinical documentation completeness and supports appropriate claim processing and reimbursement.

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    When to Use

    Use a code from this group when a patient has a documented neoplasm of uncertain behavior in a urinary organ and the clinical record or pathology report does not confirm benign or malignant status. These codes are appropriate for encounters involving evaluation, biopsy, monitoring, or treatment planning for indeterminate urinary tract lesions.

    ICD-10-CM Codes

    13 rows

    ICD-10-CM CodeDescription
    D41.00Neoplasm of uncertain behavior of unspecified kidney
    D41.01Neoplasm of uncertain behavior of right kidney
    D41.02Neoplasm of uncertain behavior of left kidney
    D41.10Neoplasm of uncertain behavior of unspecified renal pelvis
    D41.11Neoplasm of uncertain behavior of right renal pelvis
    D41.12Neoplasm of uncertain behavior of left renal pelvis
    D41.20Neoplasm of uncertain behavior of unspecified ureter
    D41.21Neoplasm of uncertain behavior of right ureter
    D41.22Neoplasm of uncertain behavior of left ureter
    D41.3Neoplasm of uncertain behavior of urethra
    D41.4Neoplasm of uncertain behavior of bladder
    D41.8Neoplasm of uncertain behavior of other specified urinary organs
    D41.9Neoplasm of uncertain behavior of unspecified urinary organ

    DRG Codes

    6 rows

    DRG CodeDescription
    656Kidney and Ureter Procedures for Neoplasm with MCC
    657Kidney and Ureter Procedures for Neoplasm with CC
    658Kidney and Ureter Procedures for Neoplasm without CC/MCC
    686Kidney and Urinary Tract Neoplasms with MCC
    687Kidney and Urinary Tract Neoplasms with CC
    688Kidney and Urinary Tract Neoplasms without CC/MCC

    Typical Clinical Scenarios

    • An adult patient presents to urology clinic with intermittent painless hematuria discovered on routine urinalysis; cystoscopy identifies a small papillary bladder lesion and biopsy reports a neoplasm of uncertain behavior of the bladder urothelium. The visit is for diagnostic evaluation and management planning while awaiting definitive pathology to rule out malignancy, so a code from this group is assigned to document the uncertain behavior of the bladder lesion. Typical codes: D41.3
    • An elderly patient with a history of recurrent urinary tract infections undergoes renal imaging for flank pain, and a partially cystic mass in the renal pelvis is found; biopsy is indeterminate and pathology describes a neoplasm of uncertain behavior of the kidney. Because the diagnosis remains indeterminate and requires surveillance and further workup rather than treatment for confirmed malignancy, a neoplasm-of-uncertain-behavior code for the kidney is used. Typical codes: D41.0, D41.01
    • A middle-aged patient hospitalized for gross hematuria and anemia has a mass near the ureteral orifice identified on imaging; intraoperative frozen section is nondiagnostic and final pathology returns neoplasm of uncertain behavior of the ureter. The code is recorded as a comorbid diagnosis to guide inpatient care, follow-up planning, and oncologic consultation while the lesion’s behavior is unresolved. Typical codes: D41.2, D41.21

    Related Codes

    D37-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-ORAL-CAVITY-DIGESTIVE-ORGANS

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Oral Cavity And Digestive Organs: Group Overview

    D38-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-MIDDLE-EAR-RESPIRATORY

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Middle Ear And Respiratory And Intrathoracic Organs: Group Overview

    D39-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-FEMALE-GENITAL

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Female Genital Organs: Group Overview

    D40-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-MALE-GENITAL

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Male Genital Organs: Group Overview

    D43-NEOPLASM-OF-UNCERTAIN-BEHAVIOR-BRAIN-CNS

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Brain And Central Nervous System: Group Overview

    D44-NEOPLASM-OF-UNCERTAIN-ENDOCRINE-BEHAVIOR

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Endocrine Glands: Group Overview

    D45-POLYCYTHEMIA-VERA

    ICD-10-CM Code For Polycythemia Vera: Group Overview

    D46-MYELODYSPLASTIC-SYNDROMES

    ICD-10-CM Code For Myelodysplastic Syndromes: Group Overview

    D47-OTHER-NEOPLASMS-UNCERTAIN-BEHAVIOR

    ICD-10-CM Code For Other Neoplasms Of Uncertain Behavior Of Lymphoid Hematopoietic And Related Tissue: Group Overview

    D48-NEOPLASM-OF-UNCERTAIN-BEHAVIOR

    ICD-10-CM Code For Neoplasm Of Uncertain Behavior Of Other And Unspecified Sites: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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