Breast Imaging Guidelines (Ohio) — Radiology Imaging Coverage Determination Guideline
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State-specific radiology imaging coverage guideline governing breast imaging services for UnitedHealthcare Community Plan members in Ohio; applies to medical necessity determinations per Ohio Administrative Code 5160-1-01.
No material clinical or coverage changes in this revision.
Coverage Criteria and Indications
General coverage considerations
Application and general determination
General coverage criteria and modality guidance
Coverage and modality selection guided by evidence-based clinical presentation and documented clinical evaluation. Specific criteria vary by condition-specific guideline sections.
Face-to-face evaluation or meaningful technological contact may be required per condition-specific guidance.
Avoid using CT to substitute for MRI unless MRI contraindicated.
Limit repetitive GBCA exposure when possible.
Unbundling PET/CT into separate PET and diagnostic CT codes is not appropriate.
Accepted clinical indications for 3D rendering (CPT® 76376/76377)
CPT® 76376 or 76377 can be considered in the following clinical scenarios:
3D rendering must not be used with 3D mammography, automated breast ultrasound (ABUS), or breast MRI.
Guidance procedure coding and limits
Guidance procedure coding rules and constraints
Stereotactic and unlisted procedure criteria
Stereotactic localization and unlisted procedure guidance
3D rendering should not be reported in conjunction with 77011 or 70486.
Examples: neurosurgical navigation/planning, custom joint arthroplasty planning, or procedures requiring thinner cuts/alternative positioning.
Use of unlisted CT/MR codes
Covered when meeting the following conditions
Provide clinical justification and documentation when submitting unlisted procedure codes.
Limited or follow-up CT (CPT 76380)
Coverage stance and limitations
Whole-body CT
Exception: whole-body low-dose skeletal CT may be supported for multiple myeloma staging per Oncology guidelines.
Whole-body MRI (WBMRI)
Report WBMRI using CPT 76498 only; other reporting methods are inappropriate.
Whole-body MRI (WBMRI)
WBMRI covered only in select circumstances
Exceptions include interval WBMRI for select cancer predisposition syndromes and limited indications in multiple myeloma or chronic recurrent multifocal osteomyelitis.
See condition-specific Pediatric/Oncology guideline sections for details.
PET/MRI
PET/MRI medically necessary when specific criteria met
Breast Ultrasound — medical necessity
Breast ultrasound coverage stance and conditions
Ultrasound follow-up and coding
Ultrasound procedural rules and follow-up
3D reconstruction (76376/76377) is NOT medically necessary for breast ultrasound.
MRI Breast — medical necessity
MRI breast coverage stance and acceptable codes
Do not bill 76376/76377 with MRI Breast since CAD/automatic 3D is included with 77049/77048.
MRI after screening mammogram/US
MRI following screening mammogram/US in asymptomatic individuals
Alternative MRI CPT/HCPCS codes may be used depending on laterality/contrast when medical necessity is met.
Breast reconstruction vascular imaging
Pre-operative imaging for breast reconstruction donor/recipient vessel planning
General medical necessity indications
MRI Breast Bilateral without and with contrast (CPT 77049 / HCPCS C8908) is medically necessary when ANY of the following indications are met:
When indicated, use supported CPT/HCPCS codes per laterality and contrast requirements.
MRI BI-RADS TM 3 follow-up criteria
Management of MRI BI-RADS TM 3 (probably benign) lesions:
High-risk screening criteria
High-risk annual MRI screening criteria (covered when ALL of the group-specific conditions are met as specified):
Certain genes (MSH2, MLH1, MSH6, PMS2, EPCAM, NBN, VUS, intermediate penetrance) are NOT sufficient for MRI screening.
Start-age rules include '10 years before earliest relative but not before age 25' where applicable.
Post-biopsy imaging criteria
Post-biopsy/attempted biopsy imaging:
Evidence supports follow-up because a small proportion of canceled MRI-guided biopsy lesions may be malignant.
High-risk/dense breast screening with MRI
Use of MRI for supplemental screening in individuals with dense breasts or high risk:
MBI may be an alternative when MRI contraindicated.
Post-biopsy or attempted biopsy imaging
Indications for MRI after biopsy issues:
Document radiologist recommendation and prior biopsy details.
Postmastectomy surveillance
Imaging after mastectomy:
Breast implant evaluation (saline and silicone)
Coverage rules differ by implant type and presentation:
Clinical exam usually detects saline rupture.
Stepwise imaging required.
Nipple discharge imaging
Different management for physiologic versus pathologic discharge:
Breast Pain (BR-7.1)
Breast Pain (Mastodynia) — Covered when ALL of the following are met
Nipple Discharge (evaluation sequence)
Nipple discharge evaluation — Covered when ALL of the following sequence is followed
Pathologic discharge has higher malignancy/high-risk lesion rate (11–16%).
MRI / MBI coverage
MRI and Molecular Breast Imaging (MBI) — Covered when ANY of the following high-risk or situational criteria are met
Routine MRI after bilateral mastectomy is NOT medically necessary.
MBI otherwise not supported for average-risk screening.
Alternative/Investigational Imaging
Alternative breast imaging techniques — Not supported or investigational
PEM has much higher radiation exposure and is generally not supported.
Male Breast Imaging (BR-9.1)
Male breast imaging — Covered when ALL of the following are met
MRI of the male breast is not medically necessary.
Palpable breast mass
Palpable breast mass
Skin changes
Skin Changes (BR-15.1)
3D rendering
3D Rendering (BR-13.1)
Concurrent physician supervision and documentation required when used for allowed indications.
Pregnancy and lactation
Pregnant or Lactating Individuals (BR-10.1)
Nipple Inversion/Retraction (congenital vs acquired/new-onset)
Guidance for nipple inversion/retraction when no palpable mass
Malignant Phyllodes Tumor - Preoperative MRI
Guidance for malignant phyllodes tumor
MRI is not useful to distinguish phyllodes from fibroadenoma, but is supported for malignant phyllodes to assess extent and resectability.
Imaging modalities, procedures, or devices that lack sufficient supporting evidence, demonstrated clinical utility, or accepted professional consensus may be considered investigational, experimental, or unproven and are subject to exclusion from coverage. Criteria for this determination include paucity of peer-reviewed evidence, absence of improved health outcomes, or lack of specialty-society or clinical community support.
Magnetic resonance imaging that uses Xenon Xe 129 (CPT® C9791) for contrast is considered investigational and experimental and is not supported by these guidelines. MRI contrast guidance in the document otherwise refers to gadolinium-based agents and their use should be limited to circumstances where the contrast materially changes clinical management.
Do not bill CPT® 76376 or 76377 in conjunction with other advanced imaging or derived studies listed in the guideline (for example: CAD, MRA, CTA, nuclear SPECT, PET/PET-CT, stereotactic localization, mammography, breast MRI, or breast ultrasound). Concurrent billing with those modalities is explicitly disallowed and may be denied.
Covered Indications (by clinical scenario)
Coding and Code Tables
| No codes listed |
| CPT (general mention) | The inclusion of any CPT code in the clinical guidelines does not imply that the code is under management or requires prior authorization. |
| C9791 | MRI utilizing Xenon Xe 129 for contrast is considered investigational and experimental at this time. |
| 19085 | Biopsy, breast, with placement of breast localization device(s), when performed, and imaging of the biopsy specimen, when performed, percutaneous; first lesion, including MR guidance |
| 19086 | Biopsy, breast, ... each additional lesion, including MR guidance |
| 75989 | Imaging guidance for percutaneous drainage with placement of catheter (all modalities) |
| 76942 | Ultrasonic guidance for needle placement |
| 77011 | CT guidance for stereotactic localization |
| 77012 | CT guidance for needle placement |
| 77013 | CT guidance for, and monitoring of parenchymal tissue ablation |
| 77021 | MR guidance for needle placement |
| 77022 | MR guidance for, and monitoring of parenchymal tissue ablation |
| C8001 | 3D anatomical segmentation imaging for preoperative planning, data preparation and transmission, obtained from previous diagnostic CT or MR examination of the same anatomy |
| 76380 | Limited or follow-up CT |
| 76140 | Interpretation of an outside study |
| 76498 | Unlisted MR procedure (used to report whole-body MRI) |
| 76498 | Unlisted magnetic resonance procedure (used to report Whole-body MRI) |
| 76641 | Ultrasound breast unilateral, complete |
| 76642 | Ultrasound breast unilateral, limited |
| 76882 | Ultrasound, axilla |
| 19083 | Breast, biopsy, percutaneous, with imaging guidance (US-guided) — includes imaging component |
| 19084 | Additional lesion biopsy |
| 76376 | 3D reconstruction (NOT medically necessary for breast ultrasound) |
| 76377 | 3D reconstruction (NOT medically necessary for breast ultrasound) |
| 77049 | MRI Breast Bilateral, without and with contrast (includes CAD) |
| 77048 | MRI Breast Unilateral, without and with contrast |
| 77047 | MRI Breast Bilateral, without contrast |
| 77046 | MRI Breast Unilateral, without contrast |
| C8908 | MRI Breast Bilateral, without and with contrast (HCPCS) |
| C8906 | MRI Breast Bilateral with contrast (HCPCS) |
| C8905 | MRI Breast Unilateral without and with contrast (HCPCS) |
| C8903 | MRI Breast Unilateral with contrast (HCPCS) |
| 19085 | MRI-guided breast biopsy (includes imaging component and needle placement) |
| 19086 | Additional lesion MRI-guided biopsy |
| 77049 | MRI Breast Bilateral without and with contrast |
| C8908 | MRI Breast Bilateral without and with contrast (HCPCS) |
| 77046 | MRI Breast Unilateral without contrast |
| 77047 | MRI Breast Bilateral without contrast |
| 77048 | MRI Breast Unilateral without and with contrast |
| C8903 | MRI Breast Unilateral with contrast |
| C8905 | MRI Breast Unilateral without and with contrast |
| C8906 | MRI Breast Bilateral with contrast |
| CPT 76641 | Breast ultrasound, unilateral |
| CPT 76642 | Breast ultrasound, bilateral |
| CPT 77047 | Magnetic resonance imaging, breast, without contrast material, bilateral (document references without contrast for implant evaluation) |
| CPT 77049 | MRI breast, bilateral, without and with contrast |
| HCPCS C8908 | MRI breast bilateral without and with contrast (alternate billing) |
| 76641 | Ultrasound, breast, unilateral, real time with image documentation |
| 76642 | Ultrasound, breast, bilateral, real time with image documentation |
| 77049 | Magnetic resonance imaging, breast, bilateral, without and with contrast |
| C8908 | Breast MRI bilateral without and with contrast (HCPCS equivalent) |
| 78800 | Breast imaging, molecular breast imaging (MBI) |
| 78811 | Positron emission tomography, breast (mentioned as requested code for PEM) |
| 0633T | CT, breast; diagnostic (listed among CT Breast series) |
| 0634T | CT, breast; diagnostic (series) |
| 0635T | CT, breast; diagnostic (series) |
| 0636T | CT, breast; diagnostic (series) |
Provider Actions, Prior Authorization and Documentation
CPT inclusion does not imply PA
The inclusion of a CPT code in this guideline does not by itself mean that the code requires prior authorization; prior authorization requirements are managed separately and condition-specific sections determine any PA needs.
CPT listing ≠ management/PA requirement
Inclusion of CPT codes in the guideline does not indicate the code is managed or requires prior authorization; verify PA requirements through applicable management policies rather than by CPT listing alone.
Justify unlisted CT (76497) / MR (76498) usage
When reporting unlisted CT (CPT 76497) or unlisted MR (CPT 76498), provide clinical justification and prefer a Category III code if available; these unlisted codes are used when no anatomic site-specific code exists.
- Document why a site-specific CPT is not appropriate (e.g., neurosurgical navigation/planning, custom joint arthroplasty planning, thinner cuts or alternative positioning).
- Provide condition- or procedure-specific justification in the submission.
PA and step requirement for PET/MRI (report as 78813+76498)
Prior authorization for PET/MRI is required when substituting for PET/CT: the patient must meet PET/CT guideline criteria AND PET/CT must be unavailable at the treating institution, with the provider specifically requesting PET/MRI; approved reporting uses CPT 78813 + CPT 76498.
Use bilateral without/with contrast codes when MRI breast indicated
When MRI of the breast is clinically indicated per the guideline, use bilateral without-and-with contrast codes (e.g., CPT 77049 or HCPCS C8908) as the preferred study and ensure coding aligns with the documented indication.
PA required for bilateral contrast breast MRI (77049/C8908)
Prior authorization is required when requesting MRI Breast bilateral without and with contrast (CPT 77049 or HCPCS C8908) to confirm medical necessity for indications such as high‑risk screening, post‑biopsy follow‑up, discordant biopsy, or radiologist/treating provider recommendation.
Provide prior imaging and BI‑RADS when requesting MRI
Document prior imaging (diagnostic mammogram and/or breast ultrasound) and their BI‑RADS interpretations when requesting subsequent breast MRI to establish medical necessity for implant evaluation, pathologic nipple discharge, or other scenarios where prior imaging is required.
- For implant evaluation: if ultrasound/mammogram indeterminate, document results before MRI (CPT 77047 may be appropriate).
- For nipple discharge or other indications, include BI‑RADS category and radiology findings in the request.
PA required for MRI (77049/C8908) and MBI (78800) requests
Prior authorization is required when requesting MRI Breast bilateral without and with contrast (CPT 77049 / HCPCS C8908) or Molecular Breast Imaging (CPT 78800) per the guideline criteria (e.g., to complete screening, radiologist recommendation, high‑risk screening, or when MRI contraindicates MBI).
- Document why MRI or MBI is indicated (radiologist recommendation, provider request to complete screening, or high‑risk criteria).
- If MRI is contraindicated and MBI is requested, document contraindication to MRI.
PA required for breast MRI and 3D rendering requests
Prior authorization is required for MRI breast bilateral without and with contrast (CPT 77049/HCPCS C8908) and for 3D rendering (CPT 76376/76377) requests; for 3D rendering, document clinical necessity given prohibitions (e.g., not with MRI breast or 3D mammography).
- If requesting 3D rendering, explain clinical scenario and document active physician supervision/participation.
- Do not bill 3D rendering with breast MRI or 3D mammography per guideline; include justification if requested regardless.
PA and documentation for preoperative MRI in malignant phyllodes
Preoperative MRI Breast bilateral without and with contrast (CPT 77049 or HCPCS C8908) is medically necessary and requires documentation of prior tissue diagnosis when requested for biopsy‑proven malignant phyllodes tumor.
- Include the prior tissue diagnosis demonstrating malignant phyllodes in the authorization request.
Document radiologist/provider recommendation and prior imaging for MRI after suspicious initial imaging
MRI Breast bilateral without and with contrast (CPT 77049/HCPCS C8908) is medically necessary for clinically suspicious cases after initial imaging (BI‑RADS 1–3) when requested by the treating provider or recommended by the radiologist; include prior imaging and findings in the request.
- If initial mammogram/US is BI‑RADS 4 or 5, MRI is not medically necessary—document biopsy plans instead.
- Document radiologist or treating provider recommendation and the imaging that prompted the MRI request.
PA process may use InterQual or plan policies
UnitedHealthcare may use InterQual or other approved internal guidelines to administer prior authorization; if InterQual lacks applicable criteria, UnitedHealthcare's Medical Policies and Coverage Determination Guidelines (approved by the Ohio Department for Medicaid Services) may be used.
Clinician judgment may override guidelines
Clinical judgment may override guideline recommendations; ensure that any divergence from guideline-based stepwise imaging is documented with the clinical rationale.
Confirm pre‑imaging clinical evaluation is completed
Ensure a clinical evaluation by the treating physician or consultant has occurred prior to ordering advanced imaging; exceptions exist for guideline‑supported scheduled follow‑up imaging.
- Document pertinent history, physical exam, labs, and prior imaging in the request.
- Telehealth or other meaningful technological contact since symptom onset may suffice if appropriate.
Not applicable
(Not applicable.)
Not applicable
(Not applicable.)
Require PET/CT criteria met before approving PET/MRI
PET/MRI requests must meet PET/CT guideline criteria first (or document PET/CT unavailability) before PET/MRI will be approved as an alternative to PET/CT.
- Document that PET/CT criteria are met and that PET/CT is not available at the treating institution if PET/MRI is requested instead.
Use ultrasound as alternative when MRI cannot be performed
When MRI cannot be performed (e.g., incompatible device, claustrophobia, inability to receive contrast), breast ultrasound may be used as a supplemental screening alternative for high‑risk females with dense breasts; document the reason MRI is not possible.
- Specify the MRI contraindication (e.g., non‑MRI compatible device, inability to receive contrast, or intolerable claustrophobia).
- If used for supplemental screening, document high‑risk status and dense breast findings.
Not applicable
(Placeholder — no action specified.)
Stepwise imaging: ultrasound ± diagnostic mammogram before MRI
Follow a stepwise imaging approach before MRI: perform breast ultrasound (CPT 76641/76642) ± diagnostic mammogram first; proceed to MRI if initial imaging is indeterminate or other MRI criteria are met.
- For palpable masses and skin changes, document diagnostic mammogram and/or ultrasound results and BI‑RADS category prior to MRI.
- If initial imaging is BI‑RADS 4 or 5, biopsy is recommended rather than MRI.
Age‑based initial imaging for focal breast pain (<30 = US; ≥30 = mammogram+US)
For focal breast pain: if age <30 years, order ultrasound first; if age ≥30 years, obtain diagnostic mammogram plus targeted ultrasound as initial imaging before considering MRI.
Perform diagnostic mammogram/US before MRI for palpable masses
Perform diagnostic mammogram and/or breast ultrasound (age‑dependent) as the initial imaging before advanced imaging (MRI) for palpable masses; if initial studies are BI‑RADS 4 or 5, proceed to biopsy rather than MRI.
Include provider or radiologist recommendation to justify MRI after screening mammogram/US
Document the radiologist or treating provider request or recommendation when requesting MRI following a screening mammogram or ultrasound; this can justify MRI to complete screening or address a finding.
- Include the radiology report recommendation or explicit provider request in the documentation.
- Attach prior mammogram/US reports and BI‑RADS assessment.
Provide complete clinical documentation for case‑by‑case determinations
For requests that require case‑by‑case determinations, include personal and family history, physical exam findings, and symptom chronology as these inform individualized coverage decisions.
- Provide detailed history, exam findings, laboratory data (if relevant), and prior imaging.
- Explain how the requested imaging will affect management.
Document physician concurrent supervision for 3D rendering
Document active physician participation/monitoring of the 3D reconstruction process when billing CPT 76376/76377, including design of the anatomic region, selection of tissues/structures to display, and monitoring/adjustment of the 3D work product.
- Failure to document concurrent supervision/participation may risk denial.
- Describe the physician's role in the reconstruction and the clinical decision supported by the 3D rendering.
Provide justification when using unlisted/HCPCS codes
When reporting HCPCS or unlisted procedure codes, provide an explanation for why a site‑specific CPT or Category III code is not available and reference the condition‑specific guideline when applicable.
- Include procedure details and clinical justification in the submission.
- Cite the applicable guideline section that supports the unlisted code use.
Document indication and use CPT 76498 for WBMRI / 78813+76498 for PET/MRI
For Whole‑body MRI or PET/MRI reporting, document the indication and adherence to condition‑specific guideline criteria; when reporting WBMRI use CPT 76498 and when reporting PET/MRI use CPT 78813 + CPT 76498 per guideline instructions.
- Document condition‑specific criteria or an explanation of PET/CT unavailability when requesting PET/MRI.
- Use CPT 76498 for WBMRI reporting as other whole‑body reporting methods are inappropriate.
Document discordant biopsy findings to support MRI requests
Document histopathologic discordance between core‑needle biopsy findings and imaging findings when requesting MRI for further evaluation after a discordant biopsy; include pathology and imaging reports.
- Include biopsy pathology report and the imaging that is discordant (BI‑RADS 4 or 5 findings that are not explained by biopsy).
- State why MRI is needed for further evaluation and how results would change management.
Include radiology/provider recommendation and prior imaging when requesting MRI
When requesting MRI, include the radiologist or treating provider recommendation, the relevant radiology report findings (e.g., mammogram/US findings prompting MRI), and timing relative to any biopsy; this information is required to establish medical necessity.
- Attach prior imaging reports and BI‑RADS assessments.
- Note the timing of MRI relative to biopsy (e.g., at least 6 months after biopsy for certain follow‑up indications).
Document prior equivocal implant imaging before requesting MRI (77047)
When initial imaging is equivocal for implant rupture, document the initial ultrasound or diagnostic mammogram and their indeterminate/BI‑RADS results before requesting MRI; MRI Breast bilateral without contrast (CPT 77047) is medically necessary if prior studies are indeterminate.
- For <30 years old: ultrasound is initial imaging; for ≥30, ultrasound or diagnostic mammogram is initial imaging.
- If prior imaging is indeterminate, include those reports to support MRI 77047 request.
Include provider/radiologist request to justify MRI after screening
Provider request or radiologist recommendation can justify MRI following a screening mammogram/US to complete screening or address a finding; include that recommendation in the authorization documentation.
Document diagnostic mammogram/US results and BI‑RADS for palpable masses and skin changes
For palpable masses and skin changes, document diagnostic mammogram and/or breast ultrasound results and BI‑RADS category; if BI‑RADS 4 or 5, document biopsy recommendation or plan rather than requesting MRI.
- Attach diagnostic mammogram and ultrasound reports with BI‑RADS assessments.
- If biopsy is planned or performed, include biopsy scheduling or results in the submission.
Provide age, presenting signs, initial imaging and tissue diagnosis for preoperative MRI
Document patient age, presence of nipple discharge or skin changes, initial imaging modality and BI‑RADS assessment, and tissue diagnosis when requesting preoperative MRI for malignant phyllodes tumor or other condition‑specific indications.
- Include tissue diagnosis for malignant phyllodes when requesting preoperative MRI.
- Provide the initial imaging and BI‑RADS to support MRI necessity.
Verify governing federal/state/contractual benefit requirements
Providers should check federal, state (Ohio Administrative Code) or contractual benefit plan coverage before using this guideline as coverage terms may differ; in the event of conflict, those requirements govern.
Denial risk: investigational, experimental, research‑only imaging
Requests for imaging that are investigational, experimental, unproven, requested for data collection only, inconsistent with established clinical standards, or lacking sufficient supporting evidence may be denied as not medically necessary.
- If the procedure is investigational or for research/data collection without clinical management intent, the request may be denied.
- Provide peer‑reviewed evidence or guideline support when requesting imaging with limited evidence.
Denial risk for overutilization or unnecessary/duplicate imaging
Requests may be denied or considered unnecessary if duplicate or questionably medically necessary imaging is ordered, if pre‑operative imaging is for a surgery that is not medically necessary, or if imaging is ordered without review of prior relevant studies and clinical history.
- Review prior imaging before ordering additional studies and document why repeat imaging is clinically necessary.
- Ensure requested imaging will affect patient management to avoid denial for overutilization.
Denial risk if 3D rendering supervision not documented
Failure to document active physician concurrent supervision or participation in the 3D reconstruction process when billing CPT 76376/76377 may result in denial; documentation should describe the physician's role in design, selection, and monitoring of the 3D product.
- Describe specific supervisory actions taken during the 3D reconstruction.
- Cite the clinical reason why 3D rendering was necessary.
Denial risk for whole‑body screening CT/MRI
Whole‑body CT screening for asymptomatic individuals and most whole‑body MRI requests are not covered or are generally not medically necessary and may be denied; WBMRI is allowed only for select cancer predisposition syndromes or specified conditions.
- If WBMRI is requested, document the specific cancer predisposition syndrome or condition that meets guideline exceptions.
- Use CPT 76498 for WBMRI reporting and include condition‑specific justification.
Denial risk for WBMRI outside listed exceptions
WBMRI is generally not medically necessary except for select cancer predisposition syndromes, multiple myeloma staging/restaging, or certain autoimmune conditions; requests outside these exceptions risk denial.
- Document condition‑specific criteria and reference the applicable oncology/pediatric guideline section when requesting WBMRI.
Denial risk for PET/MRI when criteria not met
PET/MRI is generally not medically necessary for most oncologic and neurologic conditions; requests that do not meet condition‑specific criteria or the PET/CT substitution criteria (meet PET/CT criteria and PET/CT unavailable) risk denial.
- Document why PET/CT cannot be performed at the treating institution if PET/MRI is requested instead.
- Attach condition‑specific guideline support when applicable.
Denial risk for routine ultrasound screening
Routine breast ultrasound as a stand‑alone screening test or performed with screening mammography is not medically necessary and may be denied.
- For supplemental screening in high‑risk dense breasts when MRI cannot be performed, document high‑risk status and MRI contraindication.
- Routine use for average‑risk screening is not supported.
Denial risk if contrast‑enhanced MRI performed without gadolinium when indicated
Gadolinium contrast is required for evaluation of breast parenchyma; absence of contrast when contrast‑enhanced MRI is indicated may render the MRI non‑supportable and risk denial.
- If contrast cannot be given (e.g., pregnancy, severe renal impairment), document the contraindication and consider alternative imaging per guideline.
- For implant integrity evaluation in asymptomatic individuals, non‑contrast MRI (CPT 77047) is appropriate and contrast is not necessary.
Denial risk: routine MRI after bilateral mastectomy
Routine MRI Breast following bilateral mastectomy is NOT medically necessary even if high‑risk criteria would otherwise be met and therefore may be denied.
Denial trigger: MRI for capsular contracture
Breast MRI for evaluation of capsular contracture is explicitly stated as NOT medically necessary and would be a denial trigger; do not request MRI for capsular contracture evaluation.
Denial risk for routine asymptomatic implant surveillance
Routine imaging for asymptomatic saline implants is not medically necessary and may be denied; surveillance imaging for silicone implants is managed by timing rules (see implant surveillance guidance).
- For silicone implants: routine imaging is not necessary until ≥5 years post‑placement; thereafter ultrasound is recommended and repeat every 2–3 years if negative.
- For saline implants: routine imaging for asymptomatic individuals is not indicated.
MRI supported only when MRI screening criteria met; MBI as MRI alternative when contraindicated
MRI is supported only when criteria for breast cancer screening with MRI are met; MBI may be used when MRI is indicated but contraindicated — document that MRI criteria are met and state the MRI contraindication if requesting MBI.
- If requesting MBI (CPT 78800), document why MRI is contraindicated and provide evidence that MRI screening criteria are otherwise satisfied.
Denial risk: advanced imaging for breast pain and male breast MRI
Advanced imaging for breast pain and MRI for male breast disease are generally not medically necessary and may be denied unless specific guideline indications are met and documented.
- For focal breast pain, follow age‑based initial imaging rules (US <30; mammogram+US ≥30).
- MRI for male breast disease is not medically necessary given limited supporting evidence.
High denial likelihood for male breast MRI
Requests for male breast MRI are likely to be denied because MRI of the male breast is stated to be not medically necessary in the guideline.
Denial risk for 3D rendering billed with 3D mammography/ABUS/MRI
Billing 3D rendering (CPT 76376/76377) in conjunction with 3D mammography, automated breast ultrasound (ABUS), or breast MRI is prohibited and may be denied; do not submit concurrent billing for those combinations.
- If 3D rendering is submitted, ensure it is not billed with prohibited modalities and provide justification if exceptions are claimed.
Denial risk: MRI not supported for BI‑RADS 4 or 5 initial imaging
Breast MRI is not medically necessary when the initial diagnostic mammogram or breast ultrasound is BI‑RADS category 4 or 5; document that biopsy is planned or performed rather than requesting MRI in this setting.
- If BI‑RADS 4 or 5, provide biopsy plan or pathology rather than MRI request.
- Requests for MRI in lieu of biopsy in BI‑RADS 4–5 cases risk denial.
Check governing benefit requirements; they govern in conflicts
Coverage determinations must reference federal, state (Ohio Administrative Code) or contractual benefit requirements; if those requirements conflict with this guideline, they govern—verify and document applicable benefit terms.
Contrast Use and Restrictions
Frequency and Interval Limits
Prior Authorization Notes
Excluded and Not Covered Services
PET/MRI is generally considered not medically necessary for the majority of oncologic and neurologic conditions; approval is limited to select situations when specified condition-based criteria are met or when PET/CT criteria are met but PET/CT is unavailable and the provider specifically requests PET/MRI (report as CPT® 78813 + CPT® 76498).
Whole-body MRI (WBMRI) is not established as standard evaluation for most cancer types and is generally not medically necessary except for a limited set of cancer predisposition syndromes and select autoimmune conditions; WBMRI must be reported using CPT® 76498 when authorized.
MRI using non‑gadolinium experimental agents (e.g., Xenon Xe 129) is investigational and may be excluded from coverage.
PET/MRI requests will generally be denied unless they meet condition-specific PET/MRI criteria or satisfy the guideline exception that PET/CT criteria are met and PET/CT is unavailable at the treating institution and the provider requests PET/MRI in lieu of PET/CT.
MRI techniques or contrast agents judged investigational (for example CPT® C9791 for Xenon Xe 129 contrast) are considered experimental and are not supported for coverage.
Whole-body MRI (WBMRI) is not covered for general cancer screening or routine staging outside of narrowly defined exceptions (select cancer predisposition syndromes, multiple myeloma staging/restaging, or chronic recurrent multifocal osteomyelitis). WBMRI is reportable only with CPT® 76498; reporting by assembling multiple regional MRI codes is inappropriate.
PET/MRI is not covered for most oncologic and neurologic indications unless the individual meets condition‑specific PET/MRI criteria or the PET/CT substitution criteria (meets PET/CT guideline, PET/CT unavailable, and provider requests PET/MRI).
Requests that attempt to substitute PET/CT by unbundling or without meeting the stated criteria risk denial.
Routine breast ultrasound performed as a stand‑alone screening test or paired with screening mammography is not covered. Ultrasound is an accepted supplemental screening alternative only for high‑risk females with dense breasts when MRI cannot be performed.
Three‑dimensional reconstruction codes (CPT® 76376, 76377) are not covered for breast ultrasound (including automated breast ultrasound) as there is no evidence of clinical utility.
Routine CTA (for example routine CTA chest to evaluate recipient vessels) is not medically necessary unless specific clinical exceptions apply for preoperative planning.
MRI breast surveillance following a bilateral mastectomy is not covered as routine screening even when other high‑risk screening criteria would otherwise be met.
Unilateral breast MRI is generally not covered or not clinically supported except in specific circumstances explicitly described elsewhere in the guideline; the preferred and supported study when MRI is indicated is MRI Breast Bilateral without and with contrast (CPT® 77049 / HCPCS C8908).
Breast MRI for evaluation of capsular contracture is explicitly not covered and will be denied.
When pathologic nipple discharge initial imaging (mammogram/ultrasound) is BI‑RADS category 4 or 5, breast MRI is not covered; tissue diagnosis (biopsy) is recommended instead.
There is insufficient evidence to support routine MRI screening after bilateral mastectomy; surveillance MRI after nipple‑sparing mastectomy increased biopsy rates without demonstrated survival benefit and is not supported.
Background and Scope
These guidelines are evidence‑based tools intended to aid appropriate imaging selection by summarizing peer‑reviewed literature, specialty society guidance, and expert input. They are reviewed periodically and do not replace individual clinician judgment; determinations consider clinical history, physical exam, and prior imaging when establishing medical necessity.
Definitions and Terminology
Detailed Exclusions and Not-Medically-Necessary Scenarios
Whole‑body MRI (WBMRI) is generally not covered for routine cancer screening or staging except for narrowly defined indications (select cancer predisposition syndromes and limited oncologic uses such as multiple myeloma staging/restaging). Report WBMRI only with CPT® 76498; alternative reporting methods using multiple regional MRI codes are inappropriate.
PET/MRI is generally not covered for most oncologic and neurologic conditions. It may be authorized only when the individual meets condition‑specific PET/MRI criteria or when PET/CT criteria are met but PET/CT is unavailable and PET/MRI is requested as a substitute; approved PET/MRI must be reported as CPT® 78813 + CPT® 76498.
Routine breast ultrasound is not covered as a stand‑alone screening modality or as an adjunct to screening mammography. Additionally, 3D reconstruction codes (CPT® 76376, 76377) are not supported for breast ultrasound, and other alternative imaging techniques listed in the guideline (e.g., CT breast, PEM, thermography, impedance mammography, cone‑beam CT breast) are not supported for routine screening or diagnosis.
Revision History and Versioning
Policy CSRAD002OH.F (version V2.0.2026) became effective for Ohio UnitedHealthcare Community Plan members.
Clinical review completed (last_review date recorded) in preparation for the 2026-09-01 effective version V2.0.2026.
Policy version V2.0.2026 referenced as current policy version in document metadata (version label V2.0.2026).
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