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    OpenPayerNPI Medicare & MedicaidLaboratory Corporation Of America Holdings
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    Laboratory Corporation Of America Holdings — Billing Profile & Reimbursement Data

    NPI 1033196001 · Research Triangle Park, NC · Clinical Medical Laboratory

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    Laboratory Corporation Of America Holdings is a clinical medical laboratory provider located in Research Triangle Park, North Carolina. This profile covers 103 Medicare and 198 Medicaid CPT/HCPCS procedure codes, with claims volume, average reimbursement, and total revenue by code, benchmarked against other providers billing the same services.

    Provider details (source: NPPES NPI Registry)

    FieldValue
    Entity TypeOrganization
    OrganizationLaboratory Corporation Of America Holdings
    Address1904 Alexander Dr
    CityResearch Triangle Park
    StateNC
    ZIP27709
    TaxonomyClinical Medical Laboratory
    NPI EnumeratedDecember 29, 2005

    Lifetime revenue by payer source (source: CMS Medicare & Medicaid claims data)

    Payer SourceTotal Paid
    Medicaid$53.2M
    Medicare$2.7M

    Key Findings

    LABORATORY CORPORATION OF AMERICA HOLDINGS is a long‑standing clinical medical laboratory based in RESEARCH TRIANGLE PARK, NC, with an NPI enumerated on 2005-12-29 (~21 years ago), indicating multi‑decade participation in Medicare and Medicaid billing and an established operational footprint in lab services. Its taxonomy as a Clinical Medical Laboratory aligns with the high volumes of molecular, cytogenetic, and infectious-disease testing observed across both payers.

    Medicaid dominates this provider’s lifetime public‑payer revenue: total Medicaid revenue is $53.2M versus total Medicare revenue of $2.7M, indicating the provider’s billed services to state programs are an order of magnitude larger than its Medicare activity and that it functions effectively as a Medicaid‑scale lab in North Carolina.

    Revenue concentration is high on both payers but differs by payer: precomputed figures show the top 3 Medicare codes account for 75.9% of total Medicare revenue, while the top 3 Medicaid codes account for 63.4% of total Medicaid revenue, signifying a small set of tests drive the majority of reimbursement for each payer.

    Medicare top‑code 81479 (molecular pathology, unspecified) generates $1.3M and represents 48.6% of this provider’s Medicare revenue and ranks #9 of 80 nationally (90th percentile). This placement suggests the lab is a top national participant for higher‑level molecular pathology reporting, consistent with a centralized reference testing model that handles complex, uncoded molecular procedures.

    On Medicare, the provider shows extreme national specialization in flow cytometry add‑on and interpretation codes: 88185 (38.5K claims, $616.8K, 22.8% of Medicare revenue) and 88189 (1.9K claims, $121.9K, 4.5% of Medicare revenue) both rank in the 99th percentile nationally and are labeled as extreme outliers. Those signals indicate unusually large volume relative to peers for flow‑cytometry technical and interpretation work, implying a substantial operational capacity or regional referral network for hematopathology testing.

    State‑level Medicaid volumes position this lab as a dominant in‑state provider for several specialized assays. Notably, 81229 (CGH microarray) accounts for $10.9M (21.2% of Medicaid revenue) and ranks #1 of 10 in‑state (100th percentile), and U0003 (SARS‑CoV‑2 high throughput PCR) accounts for $13.6M (26.3% of Medicaid revenue) and ranks #5 of 158 (97th percentile). These rankings show the lab is a leading in‑state provider for prenatal microarray and high‑throughput COVID testing.

    Additional Medicaid codes where the provider ranks as the top in‑state performer include 88185, 88262, 88230, 81206, 81270, 88189, and 88184 (each 100th‑percentile in‑state rank reported). Collectively these codes span flow cytometry, cytogenetics, and molecular diagnostics, reinforcing the profile of a centralized reference lab with high throughput for both genetic and hematopathology services.

    While several Medicare codes are ranked highly nationally, many other listed Medicare CPT/HCPCS entries show typical or unremarkable national volume (for example 88237, 88275, 88271, and multiple gene‑specific tests), indicating that outside of a few very large national outliers the provider’s Medicare activity includes a broad mix of standard clinical genetics and pathology testing at expected peer levels. This mix supports a hybrid business model combining specialty high‑volume assays with routine diagnostic testing.

    The combination of Medicaid dominance in revenue, repeated 100th‑percentile in‑state rankings for multiple specialized assays, and national 99th‑percentile Medicare ranks for key flow‑cytometry codes suggests the lab is both a major state‑level anchor for Medicaid testing in NC and a national referral destination for specific hematopathology and molecular procedures. That competitive standing is consistent with large reference‑lab scale and specialization rather than a small local lab.

    Medicare: Total Revenue Breakdown by CPT/HCPCS Code

    Medicare revenue breakdown by CPT/HCPCS procedure code.

    View: Bar Chart1 / 2

    Medicare: Complete Services Breakdown

    The CPT/HCPCS codes generating the most Medicare revenue for this provider.

    103 rows

    CPT/HCPCS CodeDescriptionClaimsAvg PaidRevenue
    81479Use 81479 to report a molecular pathology procedure that does not have a specific code.4,480$290$1.3M
    88185The lab analyst performs the technical component of a flow cytometry procedure using cell surface, cytoplasmic, or nuclear markers to characterize cells and aid clinicians in diagnosing patients with…38,550$20$616.8K
    88189The clinician, typically a pathologist, interprets flow cytometry results of 16 or more markers.1,940$60$121.9K
    81270The lab analyst performs the technical lab test to detect the presence of a common change in the gene for Janus kinase 2, also known as JAK2.1,000$90$89.6K
    88237The lab analyst performs a procedure to grow a culture of cells from bone marrow or blood in a neoplastic disorder.620$140$87K
    88184The lab analyst performs the technical component of a flow cytometry procedure using a cell surface, cytoplasmic, or nuclear marker to characterize cells and aid clinicians in diagnosing patients…1,620$50$84.4K
    88275The analyst performs a molecular cytogenetic test using interphase in situ hybridization and analyzes 100 to 300 cells. Interphase refers to a period of time when a cell is not dividing and…1,540$50$77K
    88271The analyst performs a molecular cytogenetic test using a DNA probe method, such as FISH, fluorescence in situ hybridization, to test cells for genetic abnormalities.2,900$20$60.8K
    81288The lab analyst performs the technical lab test involving promoter methylation analysis to detect changes for the mutL homolog 1, or MLH1 gene, also known as the colon cancer or nonpolyposis type 2…270$190$51.1K
    81272The lab analyst performs the technical lab test for a partial gene sequence analysis for the v–kit Hardy–Zuckerman 4 feline sarcoma viral oncogene homolog, or KIT, gene. The analysis does not analyze…80$320$26.8K

    Showing 1–10 of 103

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    Medicare: Competitive Analysis & Benchmarks

    How this provider's Medicare billing volume and revenue compare to other providers nationally and within its state, across 103 CPT/HCPCS codes.

    View: State1 / 2

    Full comparison — all codes billed, vs. state median

    103 rows

    CPT/HCPCS CodeRankProvider CountMedian ClaimsAvg PaidAverage Revenue
    81479110880$530$835.6K
    881851101,270$20$216.1K
    83521410100$20$152.9K
    812563101,000$60$92.7K
    860032630640$10$89.2K
    86147510270$20$83K
    862352940160$20$70.1K
    8392171050$20$63.5K
    86146510170$20$56.3K
    86008410510$20$55.3K

    Showing 1–10 of 103

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    Medicaid: Total Revenue Breakdown by CPT/HCPCS Code

    Medicaid revenue breakdown by year and by CPT/HCPCS procedure code, including monthly billing trends and the top codes driving revenue.

    View: By Year1 / 3

    Medicaid: Complete Services Breakdown

    Every CPT/HCPCS code this provider has billed to Medicaid, with claims volume, average payment, and total revenue.

    198 rows

    CPT/HCPCS CodeDescriptionClaimsAvg PaidRevenue
    U0003Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, making use of high…163,570$80$13.6M
    81229The lab analyst performs the technical lab test using comparative genomic hybridization (CGH) microarray, also referred to as chromosomal microarray (CMA) or molecular karyotype performed by…25,970$420$10.9M
    81420The lab analyst performs a genomic sequence analysis panel to evaluate circulating cell free fetal DNA in maternal blood for genetic sequences of at least the genes on chromosomes 13, 18, and 21,…10,380$790$8.2M
    88305The physician, typically a pathologist, performs a level IV examination of a surgical pathology specimen. The examination includes accessioning the specimen into the lab, which involves formally…47,550$110$5.1M
    81220The lab analyst performs the technical lab test to detect the presence of changes in the gene for cystic fibrosis transmembrane conductance regulator, also known as CFTR. The test evaluates the CFTR…18,630$180$3.4M
    80307The lab analyst performs presumptive drug test(s) via instrumented chemistry analyzers to screen for any number of drug classes on a single date.34,720$60$2.2M
    88185The lab analyst performs the technical component of a flow cytometry procedure using cell surface, cytoplasmic, or nuclear markers to characterize cells and aid clinicians in diagnosing patients with…7,630$220$1.7M
    87637The lab analyst performs the technical steps to detect and differentiate severe acute respiratory syndrome coronavirus 2 (SARS–CoV–2), influenza A, influenza B, and respiratory syncytial virus (RSV)…9,200$100$901.8K
    88262The analyst performs a chromosome analysis, a test that examines a person’s genetic material for abnormalities, counts 15 to 20 cells, and makes two karyotypes with banding, which are pictures of the…9,400$70$695.6K
    88230The lab analyst performs a procedure to grow a tissue culture for lymphocytes in a nonneoplastic disorder, typically using blood. Lymphocytes, a type of white blood cell, function as part of the…9,380$60$563K

    Showing 1–10 of 198

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    Medicaid: Competitive Analysis & Benchmarks

    How this provider's Medicaid billing volume and revenue compare to other North Carolina providers billing the same CPT/HCPCS codes.

    Full comparison — all codes billed, vs. North Carolina median

    198 rows

    CPT/HCPCS CodeDescriptionRankProvider CountMedian ClaimsAvg PaidAverage Revenue
    81420The lab analyst performs a genomic sequence analysis panel to evaluate circulating cell free fetal DNA in maternal blood for genetic sequences of at least the genes on chromosomes 13, 18, and 21,…420240$400$13.6M
    81220The lab analyst performs the technical lab test to detect the presence of changes in the gene for cystic fibrosis transmembrane conductance regulator, also known as CFTR. The test evaluates the CFTR…330170$260$2.6M
    U0003Infectious agent detection by nucleic acid (dna or rna); severe acute respiratory syndrome coronavirus 2 (sars-cov-2) (coronavirus disease [covid-19]), amplified probe technique, making use of high…5160840$70$2.3M
    81229The lab analyst performs the technical lab test using comparative genomic hybridization (CGH) microarray, also referred to as chromosomal microarray (CMA) or molecular karyotype performed by…110680$480$1.9M
    G0483Drug test(s), definitive, utilizing (1) drug identification methods able to identify individual drugs and distinguish between structural isomers (but not necessarily stereoisomers), including, but…671101,450$110$1.7M
    87801The lab analyst performs a test for multiple infectious agents using amplified nucleic acid probe technique.3040480$40$1.4M
    87798The lab analyst performs a test for an infectious agent not specified in another code using an amplified nucleic acid probe technique. Use this code if you know the laboratory technique is amplified…4780420$30$1.2M
    87661The lab analyst performs a test for Trichomonas vaginalis using nucleic acid amplified probe technique.3970280$20$896.7K
    80307The lab analyst performs presumptive drug test(s) via instrumented chemistry analyzers to screen for any number of drug classes on a single date.183601,830$40$819.8K
    86480The lab analyst performs a test to evaluate a cell mediated immunity gamma interferon antigen response to certain tuberculosis, or TB, antibodies.1420310$30$676.6K

    Showing 1–10 of 198

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    Related Providers

    Other providers that share a Tax Identification Number (TIN) with Laboratory Corporation Of America Holdings, ranked by combined Medicare and Medicaid revenue.

    ProviderStateTaxonomyMedicare RevenueMedicaid Revenue
    Laboratory Corporation Of America HoldingsNCClinical Medical Laboratory$214.6M$1.4B
    Laboratory Corporation Of America HoldingsNJClinical Medical Laboratory$143.3M$717.5M
    Natera, Inc.CAClinical Medical Laboratory$133.1M$641.5M
    Unilab CorporationCAClinical Medical Laboratory$94M$668.5M
    Quest Diagnostics IncorporatedNJClinical Medical Laboratory$111.2M$637.7M
    Bioreference Health, LLCNJClinical Medical Laboratory$66.8M$620.1M
    Laboratory Corporation Of America HoldingsOHClinical Medical Laboratory$56.9M$617M
    Millennium Health, LLCCAClinical Medical Laboratory$20.4M$579.3M
    Exact Sciences Laboratories, LLCWIClinical Medical Laboratory$299.3M$276.5M
    Aeroflow Inc.NCDurable Medical Equipment & Medical Supplies$0$571.9M

    Nearby Providers

    Other providers in the same ZIP code as Laboratory Corporation Of America Holdings, ranked by combined Medicare and Medicaid revenue.

    ProviderStateTaxonomyMedicare RevenueMedicaid Revenue
    Laboratory Corporation Of America HoldingsNCClinical Medical Laboratory$3.5M$281.4M
    Laboratory Corporation Of America HoldingsNCClinical Medical Laboratory$9.6M$115.7M
    Integrated Laboratory SolutionsNCClinical Medical Laboratory$51.4K$563.7K

    Frequently Asked Questions

    References

    1. 1.Medicare Physician & Other Practitioner by Provider and Service. CMS.gov.Provider-level Medicare Part B utilization and payment data.
    2. 2.NPPES NPI Registry. CMS.gov.National Provider Identifier registry used for provider enumeration and taxonomy metadata.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.

    Medicare Revenue by CPT/HCPCS Code
    Claims Volume vs. North Carolina Distribution
    Laboratory Corporation Of America Holdings — 11 of 25 codes billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Rank Distribution — North Carolina
    Medicaid Revenue by Year vs. North Carolina Providers
    7 of 7 years billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Claims Volume vs. North Carolina Distribution
    Laboratory Corporation Of America Holdings — 15 of 25 codes billed far more than typical (above p95)
    p5–p95 (all providers)p25–p75MedianThis providerOutlier
    Rank Distribution — North Carolina