ICD-10-PCS Code For Peripheral Vein: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group XW03 includes procedures performed to introduce therapeutic, diagnostic, nutritional, physiological, or prophylactic substances into peripheral veins. These ICD-10-PCS codes are used for inpatient documentation when percutaneous vascular access is obtained to deliver substances or agents into a peripheral venous location. Accurate coding within the ICD-10-PCS XW03 group is essential for proper inpatient reimbursement, as it captures the specific introduction procedure performed and supports clinical documentation accuracy.

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Peripheral Vein Introduction Procedure Overview

The procedures in this group involve percutaneous introduction of therapeutic, diagnostic, nutritional, physiological, or prophylactic substances into peripheral veins. These procedures target the peripheral venous system and are performed through the skin using needles or catheters to place substances without open surgical exposure. Accurate ICD-10-PCS coding of these introductions ensures inpatient records reflect the specific access method and supports appropriate reimbursement and case mix assignment.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
W	Body System	Anatomical Regions
0	Operation	Introduction
3	Body Part	Peripheral Vein

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ICD-10-PCS Code For Peripheral Vein: Procedure Code Group Overview

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Peripheral Vein Introduction Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
W	Body System	Anatomical Regions
0	Operation	Introduction
3	Body Part	Peripheral Vein

When to Use

Use a code from this group when a substance is introduced percutaneously into a peripheral vein for therapeutic, diagnostic, nutritional, physiological, or prophylactic purposes. Select the code that reflects the percutaneous approach and the peripheral venous site accessed during the inpatient encounter.

ICD-10-PCS Codes

56 rows

ICD-10-PCS Code	Description
XW03308	Introduction of Spesolimab Monoclonal Antibody into Peripheral Vein, Percutaneous Approach, New Technology Group 8
XW0330B	Introduction of Alpha1-proteinase Inhibitor into Peripheral Vein, Percutaneous Approach, New Technology Group 11
XW0331B	Introduction of Anitocabtagene Autoleucel Immunotherapy into Peripheral Vein, Percutaneous Approach, New Technology Group 11
XW0333A	Introduction of Bentracimab, Ticagrelor Reversal Agent into Peripheral Vein, Percutaneous Approach, New Technology Group 10
XW0334A	Introduction of Cefepime-taniborbactam Anti-infective into Peripheral Vein, Percutaneous Approach, New Technology Group 10
XW03357	Introduction of Narsoplimab Monoclonal Antibody into Peripheral Vein, Percutaneous Approach, New Technology Group 7
XW03358	Introduction of Mosunetuzumab Antineoplastic into Peripheral Vein, Percutaneous Approach, New Technology Group 8
XW0335A	Introduction of Ceftobiprole Medocaril Anti-infective into Peripheral Vein, Percutaneous Approach, New Technology Group 10
XW03367	Introduction of Terlipressin into Peripheral Vein, Percutaneous Approach, New Technology Group 7
XW03368	Introduction of Afamitresgene Autoleucel Immunotherapy into Peripheral Vein, Percutaneous Approach, New Technology Group 8

Showing 1–10 of 56

DRG Codes

4 rows

DRG Code	Description
018	Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies
673	Other Kidney and Urinary Tract Procedures with MCC
674	Other Kidney and Urinary Tract Procedures with CC
675	Other Kidney and Urinary Tract Procedures without CC/MCC

Typical Clinical Scenarios

An elderly patient admitted with severe neutropenic fever secondary to chemotherapy requires prompt intravenous administration of a novel anti-infective or monoclonal therapy through peripheral venous access because central access is not available and rapid drug delivery is indicated. A percutaneous peripheral vein introduction is performed to deliver the specified therapeutic agent during the inpatient stay. Typical codes: XW033E5, XW033G6
A patient with relapsed B-cell lymphoma is admitted electively for inpatient administration of a chimeric antigen receptor T-cell (CAR-T) or other engineered T-cell immunotherapy regimen that is given intravenously via peripheral vein access on the treatment day. Percutaneous peripheral venous introduction is documented to reflect the inpatient delivery of the specified immunotherapy agent. Typical codes: XW033A7, XW033C7
A patient who previously received outpatient infusions develops an in-hospital need to switch to or administer an advanced antineoplastic or immune effector cell therapy because of disease progression; peripheral venous percutaneous access is used when central access is not feasible or to expedite therapy while evaluating access options. The procedure documents inpatient introduction of the designated therapeutic substance into a peripheral vein. Typical codes: XW033F3, XW033FA

Related Codes

XW00-SKIN-INTRODUCTION

ICD-10-PCS Code For Skin: Procedure Code Group Overview

XW01-SUBCUTANEOUS-TISSUE-INTRODUCTION

ICD-10-PCS Code For Subcutaneous Tissue: Procedure Code Group Overview

XW02-MUSCLE-INTRODUCTION

ICD-10-PCS Code For Muscle: Procedure Code Group Overview

XW04-CENTRAL-VEIN-INTRODUCTION

ICD-10-PCS Code For Central Vein: Procedure Code Group Overview

XW05-PERIPHERAL-ARTERY-INTRODUCTION

ICD-10-PCS Code For Peripheral Artery: Procedure Code Group Overview

XW06-CEREBRAL-VENTRICLE-INTRODUCTION

ICD-10-PCS Code For Cerebral Ventricle: Procedure Code Group Overview

XW0D-MOUTH-AND-PHARYNX-INTRODUCTION

ICD-10-PCS Code For Mouth And Pharynx: Procedure Code Group Overview

XW0E-EAR-INTRODUCTION-EAR-S-INTRODUCTION

ICD-10-PCS Code For Ear(s): Procedure Code Group Overview

XW0G-UPPER-GI-INTRODUCTION

ICD-10-PCS Code For Upper Gi: Procedure Code Group Overview

XW0H-LOWER-GI-INTRODUCTION

ICD-10-PCS Code For Lower GI: Procedure Code Group Overview

Showing 1–10 of 17

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

56 rows

ICD-10-PCS Code	Description
XW03308	Introduction of Spesolimab Monoclonal Antibody into Peripheral Vein, Percutaneous Approach, New Technology Group 8
XW0330B	Introduction of Alpha1-proteinase Inhibitor into Peripheral Vein, Percutaneous Approach, New Technology Group 11
XW0331B	Introduction of Anitocabtagene Autoleucel Immunotherapy into Peripheral Vein, Percutaneous Approach, New Technology Group 11
XW0333A	Introduction of Bentracimab, Ticagrelor Reversal Agent into Peripheral Vein, Percutaneous Approach, New Technology Group 10
XW0334A	Introduction of Cefepime-taniborbactam Anti-infective into Peripheral Vein, Percutaneous Approach, New Technology Group 10
XW03357	Introduction of Narsoplimab Monoclonal Antibody into Peripheral Vein, Percutaneous Approach, New Technology Group 7
XW03358	Introduction of Mosunetuzumab Antineoplastic into Peripheral Vein, Percutaneous Approach, New Technology Group 8
XW0335A	Introduction of Ceftobiprole Medocaril Anti-infective into Peripheral Vein, Percutaneous Approach, New Technology Group 10
XW03367	Introduction of Terlipressin into Peripheral Vein, Percutaneous Approach, New Technology Group 7
XW03368	Introduction of Afamitresgene Autoleucel Immunotherapy into Peripheral Vein, Percutaneous Approach, New Technology Group 8

Showing 1–10 of 56

DRG Codes

4 rows

DRG Code	Description
018	Chimeric Antigen Receptor (CAR) T-Cell and Other Immunotherapies
673	Other Kidney and Urinary Tract Procedures with MCC
674	Other Kidney and Urinary Tract Procedures with CC
675	Other Kidney and Urinary Tract Procedures without CC/MCC

Typical Clinical Scenarios

An elderly patient admitted with severe neutropenic fever secondary to chemotherapy requires prompt intravenous administration of a novel anti-infective or monoclonal therapy through peripheral venous access because central access is not available and rapid drug delivery is indicated. A percutaneous peripheral vein introduction is performed to deliver the specified therapeutic agent during the inpatient stay. Typical codes: XW033E5, XW033G6
A patient with relapsed B-cell lymphoma is admitted electively for inpatient administration of a chimeric antigen receptor T-cell (CAR-T) or other engineered T-cell immunotherapy regimen that is given intravenously via peripheral vein access on the treatment day. Percutaneous peripheral venous introduction is documented to reflect the inpatient delivery of the specified immunotherapy agent. Typical codes: XW033A7, XW033C7
A patient who previously received outpatient infusions develops an in-hospital need to switch to or administer an advanced antineoplastic or immune effector cell therapy because of disease progression; peripheral venous percutaneous access is used when central access is not feasible or to expedite therapy while evaluating access options. The procedure documents inpatient introduction of the designated therapeutic substance into a peripheral vein. Typical codes: XW033F3, XW033FA

Related Codes

XW00-SKIN-INTRODUCTION

ICD-10-PCS Code For Skin: Procedure Code Group Overview

XW01-SUBCUTANEOUS-TISSUE-INTRODUCTION

ICD-10-PCS Code For Subcutaneous Tissue: Procedure Code Group Overview

XW02-MUSCLE-INTRODUCTION

ICD-10-PCS Code For Muscle: Procedure Code Group Overview

XW04-CENTRAL-VEIN-INTRODUCTION

ICD-10-PCS Code For Central Vein: Procedure Code Group Overview

XW05-PERIPHERAL-ARTERY-INTRODUCTION

ICD-10-PCS Code For Peripheral Artery: Procedure Code Group Overview

XW06-CEREBRAL-VENTRICLE-INTRODUCTION

ICD-10-PCS Code For Cerebral Ventricle: Procedure Code Group Overview

XW0D-MOUTH-AND-PHARYNX-INTRODUCTION

ICD-10-PCS Code For Mouth And Pharynx: Procedure Code Group Overview

XW0E-EAR-INTRODUCTION-EAR-S-INTRODUCTION

ICD-10-PCS Code For Ear(s): Procedure Code Group Overview

XW0G-UPPER-GI-INTRODUCTION

ICD-10-PCS Code For Upper Gi: Procedure Code Group Overview

XW0H-LOWER-GI-INTRODUCTION

ICD-10-PCS Code For Lower GI: Procedure Code Group Overview

Showing 1–10 of 17

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Peripheral Vein: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Peripheral Vein: Procedure Code Group Overview policy alerts

Peripheral Vein Introduction Procedure Overview

Code Attributes

ICD-10-PCS Code For Peripheral Vein: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Peripheral Vein: Procedure Code Group Overview policy alerts

Peripheral Vein Introduction Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which procedures are included in ICD-10-PCS code group XW03?

How should coders document procedures that fall under XW03 for inpatient records?

What are some example codes and substances in the XW03 group?

Which DRGs are related to procedures in this code group?

What code attributes define the XW03 procedure group in ICD-10-PCS?

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which procedures are included in ICD-10-PCS code group XW03?

How should coders document procedures that fall under XW03 for inpatient records?

What are some example codes and substances in the XW03 group?

Which DRGs are related to procedures in this code group?

What code attributes define the XW03 procedure group in ICD-10-PCS?

References