ICD-10-PCS Code For Muscle: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group XW02 includes procedures performed to introduce substances into muscle tissue in anatomical regions. These ICD-10-PCS codes are used for inpatient documentation when a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance is placed into or onto muscle as a novel or specialized procedure. Accurate coding within the ICD-10-PCS XW02 group is essential for proper inpatient reimbursement, as it captures the procedure performed and supports clinical documentation accuracy.

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Muscle Introduction Procedure Overview

This procedure group includes introduction procedures directed at muscles within the anatomical regions body system and classified in the New Technology section of ICD-10-PCS. These procedures involve placing therapeutic, diagnostic, nutritional, physiological, or prophylactic substances into or onto muscle tissue. Accurate coding is important for reflecting the novel or specialized nature of these introductions and for appropriate inpatient reimbursement and case mix assignment.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
W	Body System	Anatomical Regions
0	Operation	Introduction
2	Body Part	Muscle

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ICD-10-PCS Code For Muscle: Procedure Code Group Overview

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Muscle Introduction Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
X	Section	New Technology
W	Body System	Anatomical Regions
0	Operation	Introduction
2	Body Part	Muscle

When to Use

Use a code from this group when a therapeutic, diagnostic, nutritional, physiological, or prophylactic substance is deliberately introduced into or onto muscle. These codes apply specifically when the procedure targets muscle tissue and is documented as an introduction in the operative record.

ICD-10-PCS Codes

8 rows

ICD-10-PCS Code	Description
XW020D8	Introduction of Engineered Allogeneic Thymus Tissue into Muscle, Open Approach, New Technology Group 8
XW023S6	Introduction of COVID-19 Vaccine Dose 1 into Muscle, Percutaneous Approach, New Technology Group 6
XW023T6	Introduction of COVID-19 Vaccine Dose 2 into Muscle, Percutaneous Approach, New Technology Group 6
XW023U6	Introduction of COVID-19 Vaccine into Muscle, Percutaneous Approach, New Technology Group 6
XW023V7	Introduction of COVID-19 Vaccine Dose 3 into Muscle, Percutaneous Approach, New Technology Group 7
XW023W7	Introduction of COVID-19 Vaccine Booster into Muscle, Percutaneous Approach, New Technology Group 7
XW023X7	Introduction of Tixagevimab and Cilgavimab Monoclonal Antibody into Muscle, Percutaneous Approach, New Technology Group 7
XW023Y7	Introduction of Other New Technology Monoclonal Antibody into Muscle, Percutaneous Approach, New Technology Group 7

DRG Codes

6 rows

DRG Code	Description
628	Other Endocrine, Nutritional and Metabolic O.R. Procedures with MCC
629	Other Endocrine, Nutritional and Metabolic O.R. Procedures with CC
630	Other Endocrine, Nutritional and Metabolic O.R. Procedures without CC/MCC
987	Non-Extensive O.R. Procedures Unrelated to Principal Diagnosis with MCC
988	Non-Extensive O.R. Procedures Unrelated to Principal Diagnosis with CC
989	Non-Extensive O.R. Procedures Unrelated to Principal Diagnosis without CC/MCC

Typical Clinical Scenarios

An elderly patient with multiple comorbidities is admitted for observation after testing positive for COVID-19 and requires inpatient monitoring due to hypoxia and risk factors for progression; the clinical team administers the first-dose intramuscular COVID-19 vaccine during the admission to provide immunologic protection as part of a bundled inpatient preventive care strategy. Typical codes: XW023S6
A middle-aged adult hospitalized electively for participation in a clinical trial of a novel engineered allogeneic thymus tissue implant to modulate immune function; the procedure is performed in the operating room with an open approach to place the tissue into a target muscle in the anatomical region as part of the investigational therapy. Typical codes: XW020D8
An immunocompromised outpatient is admitted for treatment of persistent SARS-CoV-2 exposure with monoclonal antibody prophylaxis after prior vaccine response was inadequate; during the inpatient visit a percutaneous intramuscular injection of tixagevimab and cilgavimab is given to provide passive immunity. Typical codes: XW023X7, XW023U6

Related Codes

XW00-SKIN-INTRODUCTION

ICD-10-PCS Code For Skin: Procedure Code Group Overview

XW01-SUBCUTANEOUS-TISSUE-INTRODUCTION

ICD-10-PCS Code For Subcutaneous Tissue: Procedure Code Group Overview

XW03-PERIPHERAL-VEIN-INTRODUCTION

ICD-10-PCS Code For Peripheral Vein: Procedure Code Group Overview

XW04-CENTRAL-VEIN-INTRODUCTION

ICD-10-PCS Code For Central Vein: Procedure Code Group Overview

XW05-PERIPHERAL-ARTERY-INTRODUCTION

ICD-10-PCS Code For Peripheral Artery: Procedure Code Group Overview

XW06-CEREBRAL-VENTRICLE-INTRODUCTION

ICD-10-PCS Code For Cerebral Ventricle: Procedure Code Group Overview

XW0D-MOUTH-AND-PHARYNX-INTRODUCTION

ICD-10-PCS Code For Mouth And Pharynx: Procedure Code Group Overview

XW0E-EAR-INTRODUCTION-EAR-S-INTRODUCTION

ICD-10-PCS Code For Ear(s): Procedure Code Group Overview

XW0G-UPPER-GI-INTRODUCTION

ICD-10-PCS Code For Upper Gi: Procedure Code Group Overview

XW0H-LOWER-GI-INTRODUCTION

ICD-10-PCS Code For Lower GI: Procedure Code Group Overview

Showing 1–10 of 17

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

8 rows

ICD-10-PCS Code	Description
XW020D8	Introduction of Engineered Allogeneic Thymus Tissue into Muscle, Open Approach, New Technology Group 8
XW023S6	Introduction of COVID-19 Vaccine Dose 1 into Muscle, Percutaneous Approach, New Technology Group 6
XW023T6	Introduction of COVID-19 Vaccine Dose 2 into Muscle, Percutaneous Approach, New Technology Group 6
XW023U6	Introduction of COVID-19 Vaccine into Muscle, Percutaneous Approach, New Technology Group 6
XW023V7	Introduction of COVID-19 Vaccine Dose 3 into Muscle, Percutaneous Approach, New Technology Group 7
XW023W7	Introduction of COVID-19 Vaccine Booster into Muscle, Percutaneous Approach, New Technology Group 7
XW023X7	Introduction of Tixagevimab and Cilgavimab Monoclonal Antibody into Muscle, Percutaneous Approach, New Technology Group 7
XW023Y7	Introduction of Other New Technology Monoclonal Antibody into Muscle, Percutaneous Approach, New Technology Group 7

DRG Codes

6 rows

DRG Code	Description
628	Other Endocrine, Nutritional and Metabolic O.R. Procedures with MCC
629	Other Endocrine, Nutritional and Metabolic O.R. Procedures with CC
630	Other Endocrine, Nutritional and Metabolic O.R. Procedures without CC/MCC
987	Non-Extensive O.R. Procedures Unrelated to Principal Diagnosis with MCC
988	Non-Extensive O.R. Procedures Unrelated to Principal Diagnosis with CC
989	Non-Extensive O.R. Procedures Unrelated to Principal Diagnosis without CC/MCC

Typical Clinical Scenarios

An elderly patient with multiple comorbidities is admitted for observation after testing positive for COVID-19 and requires inpatient monitoring due to hypoxia and risk factors for progression; the clinical team administers the first-dose intramuscular COVID-19 vaccine during the admission to provide immunologic protection as part of a bundled inpatient preventive care strategy. Typical codes: XW023S6
A middle-aged adult hospitalized electively for participation in a clinical trial of a novel engineered allogeneic thymus tissue implant to modulate immune function; the procedure is performed in the operating room with an open approach to place the tissue into a target muscle in the anatomical region as part of the investigational therapy. Typical codes: XW020D8
An immunocompromised outpatient is admitted for treatment of persistent SARS-CoV-2 exposure with monoclonal antibody prophylaxis after prior vaccine response was inadequate; during the inpatient visit a percutaneous intramuscular injection of tixagevimab and cilgavimab is given to provide passive immunity. Typical codes: XW023X7, XW023U6

Related Codes

XW00-SKIN-INTRODUCTION

ICD-10-PCS Code For Skin: Procedure Code Group Overview

XW01-SUBCUTANEOUS-TISSUE-INTRODUCTION

ICD-10-PCS Code For Subcutaneous Tissue: Procedure Code Group Overview

XW03-PERIPHERAL-VEIN-INTRODUCTION

ICD-10-PCS Code For Peripheral Vein: Procedure Code Group Overview

XW04-CENTRAL-VEIN-INTRODUCTION

ICD-10-PCS Code For Central Vein: Procedure Code Group Overview

XW05-PERIPHERAL-ARTERY-INTRODUCTION

ICD-10-PCS Code For Peripheral Artery: Procedure Code Group Overview

XW06-CEREBRAL-VENTRICLE-INTRODUCTION

ICD-10-PCS Code For Cerebral Ventricle: Procedure Code Group Overview

XW0D-MOUTH-AND-PHARYNX-INTRODUCTION

ICD-10-PCS Code For Mouth And Pharynx: Procedure Code Group Overview

XW0E-EAR-INTRODUCTION-EAR-S-INTRODUCTION

ICD-10-PCS Code For Ear(s): Procedure Code Group Overview

XW0G-UPPER-GI-INTRODUCTION

ICD-10-PCS Code For Upper Gi: Procedure Code Group Overview

XW0H-LOWER-GI-INTRODUCTION

ICD-10-PCS Code For Lower GI: Procedure Code Group Overview

Showing 1–10 of 17

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-PCS Code For Muscle: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Muscle: Procedure Code Group Overview policy alerts

Muscle Introduction Procedure Overview

Code Attributes

ICD-10-PCS Code For Muscle: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Muscle: Procedure Code Group Overview policy alerts

Muscle Introduction Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

What procedures are included in the ICD-10-PCS XW02 Muscle introduction group?

Which specific ICD-10-PCS codes are listed in this XW02 group?

What are the code attributes for the XW02 Muscle introduction procedures?

How does accurate coding in XW02 affect inpatient reimbursement and documentation?

Which DRGs may be related to procedures coded from the XW02 group?

References

When to Use

ICD-10-PCS Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

What procedures are included in the ICD-10-PCS XW02 Muscle introduction group?

Which specific ICD-10-PCS codes are listed in this XW02 group?

What are the code attributes for the XW02 Muscle introduction procedures?

How does accurate coding in XW02 affect inpatient reimbursement and documentation?

Which DRGs may be related to procedures coded from the XW02 group?

References