ICD-10-PCS Code For Psychiatric Medication: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group HZ98 includes procedures performed to provide pharmacotherapy using psychiatric medication agents for substance abuse treatment. These ICD-10-PCS codes are used for inpatient documentation when replacement or maintenance psychiatric medications are administered as part of addiction treatment. Accurate coding within the ICD-10-PCS HZ98 group is essential for proper inpatient reimbursement, as it captures the pharmacotherapeutic procedure performed and supports clinical documentation accuracy.

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Psychiatric Medication Pharmacotherapy Procedure Overview

Procedures in this group involve the administration and management of replacement or maintenance medications used in the treatment of substance use disorders, focusing specifically on psychiatric medication agents rather than anatomic targets. These interventions do not target an anatomical body system but instead involve pharmacotherapeutic treatment strategies for addiction and co-occurring psychiatric symptoms. Accurate ICD-10-PCS coding of these pharmacotherapy procedures is important for inpatient reimbursement because it documents the specific therapeutic intervention provided and supports appropriate case mix and payment.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
H	Section	Substance Abuse Treatment
Z	Body System	None
9	Operation	Pharmacotherapy
8	Body Part	Psychiatric Medication

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ICD-10-PCS Code For Psychiatric Medication: Procedure Code Group Overview

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Psychiatric Medication Pharmacotherapy Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
H	Section	Substance Abuse Treatment
Z	Body System	None
9	Operation	Pharmacotherapy
8	Body Part	Psychiatric Medication

When to Use

Use a code from this group when psychiatric medication is administered, initiated, adjusted, or managed as part of inpatient substance abuse treatment. These codes apply when the pharmacotherapy intervention is documented as a therapeutic procedure for addiction rather than an anatomic procedure.

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
HZ98ZZZ	Pharmacotherapy for Substance Abuse Treatment, Psychiatric Medication

Typical Clinical Scenarios

A patient is admitted urgently after presenting with severe withdrawal from chronic benzodiazepine misuse with prominent anxiety and insomnia unresponsive to initial supportive measures. Inpatient psychiatric medication management is initiated to start a controlled replacement regimen and to stabilize psychiatric symptoms while withdrawal risks are monitored. The procedure documents initiation and administration of psychiatric medication agents specifically for treatment of the substance use disorder. Typical codes: HZ98ZZZ
A scheduled inpatient admission for stabilization and initiation of long-term maintenance pharmacotherapy in a patient with opioid use disorder and co-occurring depressive disorder. During the planned stay, psychiatric medications are started and adjusted under observation to manage both addiction-related cravings and mood symptoms as part of a structured treatment program. The intervention documents the deliberate initiation and titration of psychiatric medication agents as part of addiction treatment. Typical codes: HZ98ZZZ
A patient with recurrent relapse requiring readmission due to inadequate outpatient medication management; inpatient team revises the psychiatric medication regimen, switching agents and adjusting dosing to address continued substance use and comorbid anxiety. The procedure documents modification and management of psychiatric medication therapy to achieve stabilization and reduce relapse risk during the inpatient episode. Typical codes: HZ98ZZZ

ICD-10-PCS Code For Nicotine Replacement: Procedure Code Group Overview

HZ91-METHADONE-MAINTENANCE-PHARMACOTHERAPY

ICD-10-PCS Code for Methadone Maintenance: Procedure Code Group Overview

HZ92-LEVO-ALPHA-ACETYL-METHADOL-PHARMACOTHERAPY

ICD-10-PCS Code For Levo Alpha Acetyl Methadol: Procedure Code Group Overview

HZ93-ANTABUSE-PHARMACOTHERAPY

ICD-10-PCS Code For Antabuse: Procedure Code Group Overview

HZ94-NALTREXONE-PHARMACOTHERAPY

ICD-10-PCS Code For Naltrexone: Procedure Code Group Overview

HZ95-NALOXONE-ALTERATION

ICD-10-PCS Code For Naloxone: Procedure Code Group Overview

HZ96-CLONIDINE-PHARMACOTHERAPY

ICD-10-PCS Code For Clonidine: Procedure Code Group Overview

HZ97-BUPROPION-PHARMACOTHERAPY

ICD-10-PCS Code For Bupropion: Procedure Code Group Overview

HZ99-OTHER-REPLACEMENT-MEDICATION-PHARMACOTHERAPY

ICD-10-PCS Code For Other Replacement Medication: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
HZ98ZZZ	Pharmacotherapy for Substance Abuse Treatment, Psychiatric Medication

Typical Clinical Scenarios

A patient is admitted urgently after presenting with severe withdrawal from chronic benzodiazepine misuse with prominent anxiety and insomnia unresponsive to initial supportive measures. Inpatient psychiatric medication management is initiated to start a controlled replacement regimen and to stabilize psychiatric symptoms while withdrawal risks are monitored. The procedure documents initiation and administration of psychiatric medication agents specifically for treatment of the substance use disorder. Typical codes: HZ98ZZZ
A scheduled inpatient admission for stabilization and initiation of long-term maintenance pharmacotherapy in a patient with opioid use disorder and co-occurring depressive disorder. During the planned stay, psychiatric medications are started and adjusted under observation to manage both addiction-related cravings and mood symptoms as part of a structured treatment program. The intervention documents the deliberate initiation and titration of psychiatric medication agents as part of addiction treatment. Typical codes: HZ98ZZZ
A patient with recurrent relapse requiring readmission due to inadequate outpatient medication management; inpatient team revises the psychiatric medication regimen, switching agents and adjusting dosing to address continued substance use and comorbid anxiety. The procedure documents modification and management of psychiatric medication therapy to achieve stabilization and reduce relapse risk during the inpatient episode. Typical codes: HZ98ZZZ

ICD-10-PCS Code For Nicotine Replacement: Procedure Code Group Overview

HZ91-METHADONE-MAINTENANCE-PHARMACOTHERAPY

ICD-10-PCS Code for Methadone Maintenance: Procedure Code Group Overview

HZ92-LEVO-ALPHA-ACETYL-METHADOL-PHARMACOTHERAPY

ICD-10-PCS Code For Levo Alpha Acetyl Methadol: Procedure Code Group Overview

HZ93-ANTABUSE-PHARMACOTHERAPY

ICD-10-PCS Code For Antabuse: Procedure Code Group Overview

HZ94-NALTREXONE-PHARMACOTHERAPY

ICD-10-PCS Code For Naltrexone: Procedure Code Group Overview

HZ95-NALOXONE-ALTERATION

ICD-10-PCS Code For Naloxone: Procedure Code Group Overview

HZ96-CLONIDINE-PHARMACOTHERAPY

ICD-10-PCS Code For Clonidine: Procedure Code Group Overview

HZ97-BUPROPION-PHARMACOTHERAPY

ICD-10-PCS Code For Bupropion: Procedure Code Group Overview

HZ99-OTHER-REPLACEMENT-MEDICATION-PHARMACOTHERAPY

ICD-10-PCS Code For Other Replacement Medication: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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ICD-10-PCS Code For Psychiatric Medication: Procedure Code Group Overview

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Psychiatric Medication Pharmacotherapy Procedure Overview

Code Attributes

OpenPayer

ICD-10-PCS Code For Psychiatric Medication: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Psychiatric Medication: Procedure Code Group Overview policy alerts

Psychiatric Medication Pharmacotherapy Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

References

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

References

ICD-10-PCS Code For Psychiatric Medication: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Psychiatric Medication: Procedure Code Group Overview policy alerts

Psychiatric Medication Pharmacotherapy Procedure Overview

Code Attributes

ICD-10-PCS Code For Psychiatric Medication: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Psychiatric Medication: Procedure Code Group Overview policy alerts

Psychiatric Medication Pharmacotherapy Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

What does the ICD-10-PCS code group HZ98 represent?

Which specific ICD-10-PCS code is included in this group?

Why is accurate coding of `HZ98ZZZ` important for inpatient care?

What are the code attributes for the HZ98 group that coders should note?

Are there any related DRGs listed for `HZ98ZZZ`?

References

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

What does the ICD-10-PCS code group HZ98 represent?

Which specific ICD-10-PCS code is included in this group?

Why is accurate coding of `HZ98ZZZ` important for inpatient care?

What are the code attributes for the HZ98 group that coders should note?

Are there any related DRGs listed for `HZ98ZZZ`?

References