ICD-10-PCS Code For Nicotine Replacement: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group HZ90 includes procedures performed to provide pharmacotherapy using nicotine replacement products for the treatment of nicotine dependence. These ICD-10-PCS codes are used for inpatient documentation when nicotine replacement pharmacologic treatment is administered as part of substance abuse treatment or tobacco cessation during an inpatient stay. Accurate coding within the ICD-10-PCS HZ90 group is essential for proper inpatient reimbursement, as it captures the pharmacotherapy performed and determines appropriate case mix and payment.

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Nicotine Replacement Pharmacotherapy Procedure Overview

Procedures in this ICD-10-PCS HZ90 group involve the provision of pharmacotherapy using nicotine replacement products to treat nicotine dependence and support tobacco cessation. These interventions are part of substance abuse treatment rather than targeting a specific anatomical body system, and they typically involve medication delivery and clinical management. Accurate coding is important for inpatient reimbursement because it documents the therapeutic intervention provided and supports appropriate case mix and payment.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
H	Section	Substance Abuse Treatment
Z	Body System	None
9	Operation	Pharmacotherapy
0	Body Part	Nicotine Replacement

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ICD-10-PCS Code For Nicotine Replacement: Procedure Code Group Overview

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Nicotine Replacement Pharmacotherapy Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
H	Section	Substance Abuse Treatment
Z	Body System	None
9	Operation	Pharmacotherapy
0	Body Part	Nicotine Replacement

When to Use

Use a code from this group when nicotine replacement pharmacotherapy is provided to treat nicotine dependence during an inpatient encounter. Assign these codes to document the pharmacologic treatment component of substance abuse care for billing and clinical record purposes.

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
HZ90ZZZ	Pharmacotherapy for Substance Abuse Treatment, Nicotine Replacement

Typical Clinical Scenarios

A hospitalized patient with acute exacerbation of chronic obstructive pulmonary disease who is an active heavy smoker is admitted for respiratory failure and stabilization; during the inpatient stay the care team includes tobacco dependence treatment as part of comprehensive substance abuse management and initiates nicotine replacement therapy to reduce withdrawal and support cessation while respiratory status is addressed. Typical codes: HZ90ZZZ
A patient admitted electively to an inpatient psychiatric unit for intensive management of severe nicotine dependence co-occurring with major depressive disorder undergoes structured pharmacotherapy initiation using nicotine replacement products as part of the substance abuse treatment plan to facilitate behavioral therapy and reduce cravings during the admission. Typical codes: HZ90ZZZ
A medically complex patient on a surgical ward develops nicotine withdrawal after being unable to smoke postoperatively, resulting in agitation and tachycardia that complicate recovery; the inpatient team provides nicotine replacement pharmacotherapy to manage withdrawal symptoms and support overall postoperative care while treating the surgical condition. Typical codes: HZ90ZZZ

ICD-10-PCS Code for Methadone Maintenance: Procedure Code Group Overview

HZ92-LEVO-ALPHA-ACETYL-METHADOL-PHARMACOTHERAPY

ICD-10-PCS Code For Levo Alpha Acetyl Methadol: Procedure Code Group Overview

HZ93-ANTABUSE-PHARMACOTHERAPY

ICD-10-PCS Code For Antabuse: Procedure Code Group Overview

HZ94-NALTREXONE-PHARMACOTHERAPY

ICD-10-PCS Code For Naltrexone: Procedure Code Group Overview

HZ95-NALOXONE-ALTERATION

ICD-10-PCS Code For Naloxone: Procedure Code Group Overview

HZ96-CLONIDINE-PHARMACOTHERAPY

ICD-10-PCS Code For Clonidine: Procedure Code Group Overview

HZ97-BUPROPION-PHARMACOTHERAPY

ICD-10-PCS Code For Bupropion: Procedure Code Group Overview

HZ98-PSYCHIATRIC-MEDICATION-PHARMACOTHERAPY

ICD-10-PCS Code For Psychiatric Medication: Procedure Code Group Overview

HZ99-OTHER-REPLACEMENT-MEDICATION-PHARMACOTHERAPY

ICD-10-PCS Code For Other Replacement Medication: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
HZ90ZZZ	Pharmacotherapy for Substance Abuse Treatment, Nicotine Replacement

Typical Clinical Scenarios

A hospitalized patient with acute exacerbation of chronic obstructive pulmonary disease who is an active heavy smoker is admitted for respiratory failure and stabilization; during the inpatient stay the care team includes tobacco dependence treatment as part of comprehensive substance abuse management and initiates nicotine replacement therapy to reduce withdrawal and support cessation while respiratory status is addressed. Typical codes: HZ90ZZZ
A patient admitted electively to an inpatient psychiatric unit for intensive management of severe nicotine dependence co-occurring with major depressive disorder undergoes structured pharmacotherapy initiation using nicotine replacement products as part of the substance abuse treatment plan to facilitate behavioral therapy and reduce cravings during the admission. Typical codes: HZ90ZZZ
A medically complex patient on a surgical ward develops nicotine withdrawal after being unable to smoke postoperatively, resulting in agitation and tachycardia that complicate recovery; the inpatient team provides nicotine replacement pharmacotherapy to manage withdrawal symptoms and support overall postoperative care while treating the surgical condition. Typical codes: HZ90ZZZ

ICD-10-PCS Code for Methadone Maintenance: Procedure Code Group Overview

HZ92-LEVO-ALPHA-ACETYL-METHADOL-PHARMACOTHERAPY

ICD-10-PCS Code For Levo Alpha Acetyl Methadol: Procedure Code Group Overview

HZ93-ANTABUSE-PHARMACOTHERAPY

ICD-10-PCS Code For Antabuse: Procedure Code Group Overview

HZ94-NALTREXONE-PHARMACOTHERAPY

ICD-10-PCS Code For Naltrexone: Procedure Code Group Overview

HZ95-NALOXONE-ALTERATION

ICD-10-PCS Code For Naloxone: Procedure Code Group Overview

HZ96-CLONIDINE-PHARMACOTHERAPY

ICD-10-PCS Code For Clonidine: Procedure Code Group Overview

HZ97-BUPROPION-PHARMACOTHERAPY

ICD-10-PCS Code For Bupropion: Procedure Code Group Overview

HZ98-PSYCHIATRIC-MEDICATION-PHARMACOTHERAPY

ICD-10-PCS Code For Psychiatric Medication: Procedure Code Group Overview

HZ99-OTHER-REPLACEMENT-MEDICATION-PHARMACOTHERAPY

ICD-10-PCS Code For Other Replacement Medication: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

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ICD-10-PCS Code For Nicotine Replacement: Procedure Code Group Overview

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Nicotine Replacement Pharmacotherapy Procedure Overview

Code Attributes

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ICD-10-PCS Code For Nicotine Replacement: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Nicotine Replacement: Procedure Code Group Overview policy alerts

Nicotine Replacement Pharmacotherapy Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

References

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

References

ICD-10-PCS Code For Nicotine Replacement: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Nicotine Replacement: Procedure Code Group Overview policy alerts

Nicotine Replacement Pharmacotherapy Procedure Overview

Code Attributes

ICD-10-PCS Code For Nicotine Replacement: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Nicotine Replacement: Procedure Code Group Overview policy alerts

Nicotine Replacement Pharmacotherapy Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code represents nicotine replacement pharmacotherapy for substance abuse treatment?

What type of procedures are included in the HZ90 code group?

In which ICD-10-PCS section is `HZ90ZZZ` classified?

How does accurate coding of `HZ90ZZZ` affect inpatient reimbursement?

Does the HZ90 code group reference a specific anatomical body system?

References

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-PCS code represents nicotine replacement pharmacotherapy for substance abuse treatment?

What type of procedures are included in the HZ90 code group?

In which ICD-10-PCS section is `HZ90ZZZ` classified?

How does accurate coding of `HZ90ZZZ` affect inpatient reimbursement?

Does the HZ90 code group reference a specific anatomical body system?

References