ICD-10-PCS Code For Clonidine: Procedure Code Group Overview

The International Classification of Diseases, Tenth Revision, Procedure Coding System (ICD-10-PCS) code group HZ96 includes procedures performed to administer pharmacotherapy for substance abuse treatment with clonidine. These ICD-10-PCS codes are used for inpatient documentation when clonidine is provided as part of a medication regimen for treatment of addiction or withdrawal management. Accurate coding within the ICD-10-PCS HZ96 group is essential for proper inpatient reimbursement, as it captures the pharmacologic treatment performed and supports clinical documentation accuracy.

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Clonidine Pharmacotherapy Procedure Overview

Procedures in this group involve the administration and management of clonidine as a pharmacotherapy for substance abuse treatment. These interventions are not directed at a specific anatomical body system but focus on providing a medication used to support addiction treatment and symptom management. Accurate coding ensures the inpatient record reflects the pharmacologic treatment given and supports appropriate case mix assignment and reimbursement.

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
H	Section	Substance Abuse Treatment
Z	Body System	None
9	Operation	Pharmacotherapy
6	Body Part	Clonidine

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ICD-10-PCS Code For Clonidine: Procedure Code Group Overview

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Clonidine Pharmacotherapy Procedure Overview

Code Attributes

Character	ICD-10-PCS Category	Code Group Details
H	Section	Substance Abuse Treatment
Z	Body System	None
9	Operation	Pharmacotherapy
6	Body Part	Clonidine

When to Use

Use a code from this group when clonidine is administered in the inpatient setting specifically for treatment of substance abuse or management of withdrawal symptoms. These codes apply when clonidine is part of the therapeutic pharmacologic regimen provided during the inpatient encounter.

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
HZ96ZZZ	Pharmacotherapy for Substance Abuse Treatment, Clonidine

Typical Clinical Scenarios

A middle-aged patient admitted for severe alcohol withdrawal with autonomic hyperactivity and agitation unresponsive to benzodiazepine escalation; the care team initiates inpatient pharmacologic management to control sympathetic overdrive and reduce withdrawal symptoms as part of a monitored detox protocol. Clonidine is provided as part of the medication regimen to decrease adrenergic symptoms and facilitate stabilization during the acute withdrawal period. Typical codes: HZ96ZZZ
An adult enrolled in an inpatient substance use treatment program for opioid dependence who is admitted electively for medically supervised detoxification and initiation of adjunctive medications to support withdrawal management and reduce cravings. During the planned admission, clonidine is administered to manage autonomic symptoms and support comfort while other addiction therapies are started. Typical codes: HZ96ZZZ
An inpatient transfer from a psychiatric unit after recurrent severe stimulant withdrawal with persistent hypertension and sleep disturbance despite prior outpatient attempts at management; clonidine is added to the inpatient medication plan to address refractory autonomic symptoms and allow participation in behavioral treatment. The procedure documents pharmacotherapy specifically aimed at substance-related withdrawal symptom control. Typical codes: HZ96ZZZ

ICD-10-PCS Code For Nicotine Replacement: Procedure Code Group Overview

HZ91-METHADONE-MAINTENANCE-PHARMACOTHERAPY

ICD-10-PCS Code for Methadone Maintenance: Procedure Code Group Overview

HZ92-LEVO-ALPHA-ACETYL-METHADOL-PHARMACOTHERAPY

ICD-10-PCS Code For Levo Alpha Acetyl Methadol: Procedure Code Group Overview

HZ93-ANTABUSE-PHARMACOTHERAPY

ICD-10-PCS Code For Antabuse: Procedure Code Group Overview

HZ94-NALTREXONE-PHARMACOTHERAPY

ICD-10-PCS Code For Naltrexone: Procedure Code Group Overview

HZ95-NALOXONE-ALTERATION

ICD-10-PCS Code For Naloxone: Procedure Code Group Overview

HZ97-BUPROPION-PHARMACOTHERAPY

ICD-10-PCS Code For Bupropion: Procedure Code Group Overview

HZ98-PSYCHIATRIC-MEDICATION-PHARMACOTHERAPY

ICD-10-PCS Code For Psychiatric Medication: Procedure Code Group Overview

HZ99-OTHER-REPLACEMENT-MEDICATION-PHARMACOTHERAPY

ICD-10-PCS Code For Other Replacement Medication: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-PCS Codes

1 rows

ICD-10-PCS Code	Description
HZ96ZZZ	Pharmacotherapy for Substance Abuse Treatment, Clonidine

Typical Clinical Scenarios

A middle-aged patient admitted for severe alcohol withdrawal with autonomic hyperactivity and agitation unresponsive to benzodiazepine escalation; the care team initiates inpatient pharmacologic management to control sympathetic overdrive and reduce withdrawal symptoms as part of a monitored detox protocol. Clonidine is provided as part of the medication regimen to decrease adrenergic symptoms and facilitate stabilization during the acute withdrawal period. Typical codes: HZ96ZZZ
An adult enrolled in an inpatient substance use treatment program for opioid dependence who is admitted electively for medically supervised detoxification and initiation of adjunctive medications to support withdrawal management and reduce cravings. During the planned admission, clonidine is administered to manage autonomic symptoms and support comfort while other addiction therapies are started. Typical codes: HZ96ZZZ
An inpatient transfer from a psychiatric unit after recurrent severe stimulant withdrawal with persistent hypertension and sleep disturbance despite prior outpatient attempts at management; clonidine is added to the inpatient medication plan to address refractory autonomic symptoms and allow participation in behavioral treatment. The procedure documents pharmacotherapy specifically aimed at substance-related withdrawal symptom control. Typical codes: HZ96ZZZ

ICD-10-PCS Code For Nicotine Replacement: Procedure Code Group Overview

HZ91-METHADONE-MAINTENANCE-PHARMACOTHERAPY

ICD-10-PCS Code for Methadone Maintenance: Procedure Code Group Overview

HZ92-LEVO-ALPHA-ACETYL-METHADOL-PHARMACOTHERAPY

ICD-10-PCS Code For Levo Alpha Acetyl Methadol: Procedure Code Group Overview

HZ93-ANTABUSE-PHARMACOTHERAPY

ICD-10-PCS Code For Antabuse: Procedure Code Group Overview

HZ94-NALTREXONE-PHARMACOTHERAPY

ICD-10-PCS Code For Naltrexone: Procedure Code Group Overview

HZ95-NALOXONE-ALTERATION

ICD-10-PCS Code For Naloxone: Procedure Code Group Overview

HZ97-BUPROPION-PHARMACOTHERAPY

ICD-10-PCS Code For Bupropion: Procedure Code Group Overview

HZ98-PSYCHIATRIC-MEDICATION-PHARMACOTHERAPY

ICD-10-PCS Code For Psychiatric Medication: Procedure Code Group Overview

HZ99-OTHER-REPLACEMENT-MEDICATION-PHARMACOTHERAPY

ICD-10-PCS Code For Other Replacement Medication: Procedure Code Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

OpenPayer

ICD-10-PCS Code For Clonidine: Procedure Code Group Overview

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Clonidine Pharmacotherapy Procedure Overview

Code Attributes

OpenPayer

ICD-10-PCS Code For Clonidine: Procedure Code Group Overview

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Clonidine Pharmacotherapy Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

References

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

References

ICD-10-PCS Code For Clonidine: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Clonidine: Procedure Code Group Overview policy alerts

Clonidine Pharmacotherapy Procedure Overview

Code Attributes

ICD-10-PCS Code For Clonidine: Procedure Code Group Overview

Sign up for ICD-10-PCS Code For Clonidine: Procedure Code Group Overview policy alerts

Clonidine Pharmacotherapy Procedure Overview

Code Attributes

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

What procedure does the ICD-10-PCS code group HZ96 represent?

Which specific ICD-10-PCS code is listed in this procedure group?

What is the primary purpose of coding within the HZ96 group?

Under which ICD-10-PCS section and operation is clonidine pharmacotherapy classified?

How does accurate use of `HZ96ZZZ` affect billing and reimbursement processes?

References

When to Use

ICD-10-PCS Codes

Typical Clinical Scenarios

Related Codes

What procedure does the ICD-10-PCS code group HZ96 represent?

Which specific ICD-10-PCS code is listed in this procedure group?

What is the primary purpose of coding within the HZ96 group?

Under which ICD-10-PCS section and operation is clonidine pharmacotherapy classified?

How does accurate use of `HZ96ZZZ` affect billing and reimbursement processes?

References