HCPCS J1100: Dexamethasone Sodium Phosphate Injection, 1 mg

HCPCS Level II code J1100 describes an injection of dexamethasone sodium phosphate, 1 mg, used for corticosteroid therapy; the service is an intravenous or intramuscular medication administration typically performed in hospital outpatient departments, physician offices, or clinic settings for anti-inflammatory and immunosuppressive indications.

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Clinical & Coding Specifications

Clinical Context

A typical patient is an adult presenting to an outpatient clinic, urgent care center, or emergency department with moderate to severe inflammatory symptoms such as acute gout flare, allergic reaction, severe asthma exacerbation, or localized inflammatory pain requiring corticosteroid therapy. A clinician assesses the patient, documents the diagnosis (for example, acute gout M10.9, allergic reaction T78.2X1A, or asthma exacerbation J45.901), obtains consent for an intramuscular or intra-articular corticosteroid injection, verifies allergies and current medications, and prepares dexamethasone sodium phosphate for administration. The medication is drawn in the appropriate dose (multiples of 1 mg per J1100 unit), administered via intramuscular, intra-articular, or soft-tissue injection depending on indication, and the patient is observed briefly for adverse reactions. Post-procedure documentation includes medication name and strength, route, site, lot number, consent, and any immediate patient response. Billing uses HCPCS Level II code J1100 per 1 mg unit and may include an appropriate CPT code for the injection procedure or evaluation/management code if separately billable.

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`96372`	Therapeutic, prophylactic, or diagnostic injection (subcutaneous or intramuscular)	Commonly reported when `dexamethasone` is given via intramuscular injection in an outpatient or urgent care setting.
`20610`	Arthrocentesis, aspiration and/or injection; major joint or bursa (e.g., shoulder, hip)	Used when `dexamethasone` is injected intra-articularly into a major joint; the procedure code reports the joint injection.
`20550`	Injection(s); single tendon sheath, or ligament, aponeurosis (e.g., plantar "fascia")	Used for soft-tissue corticosteroid injections into tendon sheaths or small joints when `dexamethasone` is the agent.
`99213`	Office or other outpatient visit for the evaluation and management of an established patient, moderate complexity	May be reported separately with modifier `25` when an E/M visit is significant and distinct from the injection service.
`96374`	Therapeutic, prophylactic, or diagnostic injection; each additional sequential infusion (same day)

Related Modifiers

6 rows

Modifier	Description	When to Use
59	Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…	- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
76	Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…	- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
77	Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…	- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
25	CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…	- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207Q00000X	Family Medicine Physician	Family Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
208000000X	Pediatrics Physician	A pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
207R00000X	Internal Medicine Physician	A physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults…
207L00000X	Anesthesiology Physician	An anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
207P00000X	Emergency Medicine Physician	An emergency physician focuses on the immediate decision making and action necessary to prevent death or any further disability both in the pre-hospit…
207RC0001X	Clinical Cardiac Electrophysiology Physician	A field of special interest within the subspecialty of cardiovascular disease, specialty of Internal Medicine, which involves intricate technical proc…
282J00000X	Religious Nonmedical Health Care Institution	Furnishes only nonmedical nursing items and services to patients who choose to rely solely upon a religious method of healing, and for whom the accept…
133V00000X	Registered Dietitian	A Registered Dietitian (RD)/Registered Dietitian Nutritionist (RDN) is an individual uniquely trained in the science of nutrition and practice of diet…

Related Payer Policy Updates

Specialty: Hematology/Oncology1 / 3

10 rows

Policy	Payer	Effective Date
Epithelial Cell Cytology in Breast Cancer Risk Assessment	Oscar Health	2026-10-01
Chemotherapy Observation or Inpatient Hospitalization (for New Mexico Only)	UnitedHealthcare	2026-08-01
Umbilical Cord Blood Harvesting and Storage for Future Use (for Indiana Only)	UnitedHealthcare	2026-08-01
Antibody-Drug Conjugates	Premera Bluecross	2026-08-01
Chimeric Antigen Receptor (CAR) T-Cell Therapy	Colorado Rocky Mountain Health Plans	2026-08-01
Allogeneic Hematopoietic Progenitor Cell Therapy	Ambetter Georgia	2026-08-01
Umbilical Cord Blood Harvesting and Storage for Future Use (for Idaho Only)	UnitedHealthcare	2026-08-01
Umbilical Cord Blood Harvesting and Storage for Future Use (for New Jersey Only)	UnitedHealthcare	2026-08-01
Umbilical Cord Blood Harvesting and Storage for Future Use (for Ohio Only)	UnitedHealthcare	2026-08-01
Reblozyl (luspatercept-aamt) Medical Benefit Drug Policy	UnitedHealthcare	2026-08-01

Related Codes

HCPCS-J0013-ESKETAMINE-NASAL-SPRAY-1MG

HCPCS Level II J0013: Esketamine Nasal Spray, 1 mg

HCPCS-J0120-INJECTION-TETRACYCLINE-250MG

HCPCS Level II J0120: Injection, Tetracycline, up to 250 mg

HCPCS-J0121-OMADACYCLINE-INJECTION-1MG

HCPCS Level II J0121: Omadacycline Injection, 1 mg

HCPCS-J0122-ERAVACYCLINE-INJECTION-1MG

HCPCS Level II J0122: Injection, eravacycline, 1 mg

HCPCS-J0129-ABATACEPT-INJECTION-10MG-PHYSICIAN-SUPERVISED

HCPCS Level II J0129: Abatacept Injection, 10 mg

HCPCS-J0130-INJECTION-ABCIXIMAB-10MG

HCPCS Level II J0130: Injection abciximab, 10 mg

HCPCS-J0131-INJECTION-ACETAMINOPHEN-10MG-PARENTERAL-ANALGESIC

HCPCS Level II J0131: Injection, Acetaminophen 10 mg

HCPCS-J0132-INJECTION-ACETYLCYSTEINE-100MG-INJECTABLE-MEDICATION

HCPCS Level II J0132: Injection, Acetylcysteine 100 mg

HCPCS-J0133-ACYCLOVIR-INJECTION-5MG

HCPCS Level II J0133: Injection, Acyclovir 5 mg

HCPCS-J0134-ACETAMINOPHEN-INJECTION-FRESENIUS-KABI-10MG

HCPCS Level II J0134: Injection, Acetaminophen (10 mg)

Showing 1–10 of 991

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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Clinical & Coding Specifications

Clinical Context

Related CPT Codes

CPT Code	Description	Relationship to This Procedure
`96372`	Therapeutic, prophylactic, or diagnostic injection (subcutaneous or intramuscular)	Commonly reported when `dexamethasone` is given via intramuscular injection in an outpatient or urgent care setting.
`20610`	Arthrocentesis, aspiration and/or injection; major joint or bursa (e.g., shoulder, hip)	Used when `dexamethasone` is injected intra-articularly into a major joint; the procedure code reports the joint injection.
`20550`	Injection(s); single tendon sheath, or ligament, aponeurosis (e.g., plantar "fascia")	Used for soft-tissue corticosteroid injections into tendon sheaths or small joints when `dexamethasone` is the agent.
`99213`	Office or other outpatient visit for the evaluation and management of an established patient, moderate complexity	May be reported separately with modifier `25` when an E/M visit is significant and distinct from the injection service.
`96374`	Therapeutic, prophylactic, or diagnostic injection; each additional sequential infusion (same day)

Related Modifiers

6 rows

Modifier	Description	When to Use
59	Modifier 59 indicates a distinct procedural service when two procedures that are not normally billed together are clinically and procedurally separate. The CPT definition (as reiterated by CMS)…	- Use modifier -59 to report a distinct procedural service when documentation supports that the procedure reported is not normally billed together with another service on the same day because of a…
76	Modifier -76, Repeat Procedure or Service by Same Physician or Other Qualified Health Care Professional, is appended when the same provider performs an identical, medically necessary procedure or…	- Use modifier -76 when the same physician or other qualified health care professional performs an identical procedure or service a second (or subsequent) time on the same date of service and the…
77	Modifier 77 indicates that a previously performed procedure or service was legitimately repeated by a different physician or other qualified health care professional. The AMA’s CPT definition…	- Use modifier 77 when a basic procedure or service already performed is repeated by a different physician or other qualified health care professional (for example, a second provider independently…
52	Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…	- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
53	Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…	- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
25	CPT modifier 25 indicates that on the same day as another procedure or service, the same physician or other qualified health care professional provided a significant, separately identifiable…	- When to apply: Use modifier 25 only on an E/M code to indicate the same provider delivered a significant, separately identifiable E/M service on the same day as another procedure or service — i.e.,…

Related Provider Taxonomies

8 rows

Taxonomy Code	Specialty	Notes
207Q00000X	Family Medicine Physician	Family Medicine is the medical specialty which is concerned with the total health care of the individual and the family. It is the specialty in breadt…
208000000X	Pediatrics Physician	A pediatrician is concerned with the physical, emotional and social health of children from birth to young adulthood. Care encompasses a broad spectru…
207R00000X	Internal Medicine Physician	A physician who provides long-term, comprehensive care in the office and the hospital, managing both common and complex illness of adolescents, adults…
207L00000X	Anesthesiology Physician	An anesthesiologist is trained to provide pain relief and maintenance, or restoration, of a stable condition during and immediately following an opera…
207P00000X	Emergency Medicine Physician	An emergency physician focuses on the immediate decision making and action necessary to prevent death or any further disability both in the pre-hospit…
207RC0001X	Clinical Cardiac Electrophysiology Physician	A field of special interest within the subspecialty of cardiovascular disease, specialty of Internal Medicine, which involves intricate technical proc…
282J00000X	Religious Nonmedical Health Care Institution	Furnishes only nonmedical nursing items and services to patients who choose to rely solely upon a religious method of healing, and for whom the accept…
133V00000X	Registered Dietitian	A Registered Dietitian (RD)/Registered Dietitian Nutritionist (RDN) is an individual uniquely trained in the science of nutrition and practice of diet…

Related Payer Policy Updates

Specialty: Hematology/Oncology1 / 3

10 rows

Policy	Payer	Effective Date
Epithelial Cell Cytology in Breast Cancer Risk Assessment	Oscar Health	2026-10-01
Chemotherapy Observation or Inpatient Hospitalization (for New Mexico Only)	UnitedHealthcare	2026-08-01
Umbilical Cord Blood Harvesting and Storage for Future Use (for Indiana Only)	UnitedHealthcare	2026-08-01
Antibody-Drug Conjugates	Premera Bluecross	2026-08-01
Chimeric Antigen Receptor (CAR) T-Cell Therapy	Colorado Rocky Mountain Health Plans	2026-08-01
Allogeneic Hematopoietic Progenitor Cell Therapy	Ambetter Georgia	2026-08-01
Umbilical Cord Blood Harvesting and Storage for Future Use (for Idaho Only)	UnitedHealthcare	2026-08-01
Umbilical Cord Blood Harvesting and Storage for Future Use (for New Jersey Only)	UnitedHealthcare	2026-08-01
Umbilical Cord Blood Harvesting and Storage for Future Use (for Ohio Only)	UnitedHealthcare	2026-08-01
Reblozyl (luspatercept-aamt) Medical Benefit Drug Policy	UnitedHealthcare	2026-08-01

Related Codes

HCPCS-J0013-ESKETAMINE-NASAL-SPRAY-1MG

HCPCS Level II J0013: Esketamine Nasal Spray, 1 mg

HCPCS-J0120-INJECTION-TETRACYCLINE-250MG

HCPCS Level II J0120: Injection, Tetracycline, up to 250 mg

HCPCS-J0121-OMADACYCLINE-INJECTION-1MG

HCPCS Level II J0121: Omadacycline Injection, 1 mg

HCPCS-J0122-ERAVACYCLINE-INJECTION-1MG

HCPCS Level II J0122: Injection, eravacycline, 1 mg

HCPCS-J0129-ABATACEPT-INJECTION-10MG-PHYSICIAN-SUPERVISED

HCPCS Level II J0129: Abatacept Injection, 10 mg

HCPCS-J0130-INJECTION-ABCIXIMAB-10MG

HCPCS Level II J0130: Injection abciximab, 10 mg

HCPCS-J0131-INJECTION-ACETAMINOPHEN-10MG-PARENTERAL-ANALGESIC

HCPCS Level II J0131: Injection, Acetaminophen 10 mg

HCPCS-J0132-INJECTION-ACETYLCYSTEINE-100MG-INJECTABLE-MEDICATION

HCPCS Level II J0132: Injection, Acetylcysteine 100 mg

HCPCS-J0133-ACYCLOVIR-INJECTION-5MG

HCPCS Level II J0133: Injection, Acyclovir 5 mg

HCPCS-J0134-ACETAMINOPHEN-INJECTION-FRESENIUS-KABI-10MG

HCPCS Level II J0134: Injection, Acetaminophen (10 mg)

Showing 1–10 of 991

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

HCPCS J1100: Dexamethasone Sodium Phosphate Injection, 1 mg

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HCPCS J1100: Dexamethasone Sodium Phosphate Injection, 1 mg

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Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Payer Policy Updates

Related Codes

What does HCPCS code J1100 describe and how is it reported?

Which CPT or procedure codes are commonly billed alongside J1100?

What documentation elements are important when billing J1100?

For which diagnoses is dexamethasone (J1100) commonly used according to the page?

Which payers cover J1100 and are there payer-specific billing rules included?

References

Clinical & Coding Specifications

Clinical Context

Related CPT Codes

Related Modifiers

Related Provider Taxonomies

Related Payer Policy Updates

Related Codes

What does HCPCS code J1100 describe and how is it reported?

Which CPT or procedure codes are commonly billed alongside J1100?

What documentation elements are important when billing J1100?

For which diagnoses is dexamethasone (J1100) commonly used according to the page?

Which payers cover J1100 and are there payer-specific billing rules included?

References