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    v1.0.30
    OpenPayerBilling CodesDrugs Administered Other than Oral MethodHCPCS hcpcs-j0130-injection-abciximab-10mg
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    HCPCS Level II J0130: Injection abciximab, 10 mg

    HCPCS Level II code J0130 represents a 10 mg injection of abciximab, a platelet aggregation inhibitor used during percutaneous coronary interventions (PCI) and other acute coronary procedures; the code denotes the drug supply for an intravenous medication administration typically provided in hospital inpatient, hospital outpatient, or ambulatory surgical center settings.

    For related coverage guidance, see recent payer policy updates: Hematology - Adzynma, Tumor Treating Fields for Pancreatic Cancer, Axicabtagene ciloleucel (Yescarta®) coverage.

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is an adult admitted to a cardiac catheterization laboratory or monitored interventional suite for percutaneous coronary intervention (PCI) to treat an acute ST-elevation myocardial infarction (STEMI) or unstable angina with high thrombotic burden. The patient arrives with chest pain, ischemic ECG changes, and elevated cardiac biomarkers. After coronary angiography confirms a culprit lesion with large intracoronary thrombus or during high-risk PCI (e.g., saphenous vein graft intervention, friable thrombus, or complex bifurcation stenting), the interventional cardiology team administers J0130 (abciximab, 10 mg) as an adjunct platelet glycoprotein IIb/IIIa inhibitor to reduce periprocedural thrombotic complications.

    Workflow steps:

    • Pre-procedure assessment and informed consent, including review of bleeding risk and current antiplatelet/anticoagulant medications.

    • Vascular access and diagnostic coronary angiography to localize the lesion.

    • Decision to use a glycoprotein IIb/IIIa inhibitor based on thrombus burden or no-reflow risk.

    • Preparation and administration of J0130 per institutional protocol (bolus intravenous dose, often followed by infusion from a separate HCPCS/infusion code if used).

    • Continuous hemodynamic and bleeding monitoring in the cath lab and recovery area; documentation of dose, route, and clinical indication in the procedure note.

    • Post-procedure management including dual antiplatelet therapy, hemoglobin/hematocrit surveillance, and documentation for billing that links J0130 to the qualifying diagnosis and procedure codes.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    92928Percutaneous transcatheter placement of intracoronary stent(s), with coronary angioplasty when performed; single major coronary artery or branchCommon primary intervention (PCI with stent) during which J0130 may be administered for high thrombotic risk.

    92984 | Percutaneous transcatheter placement of intracoronary stent(s), additional branch of same vessel (each) | Additional stenting during the same PCI where adjunctive use of J0130 may occur.

    93458 | Catheterization, intraprocedural imaging, and physiological measurements during cardiac catheterization including coronary angiography when performed; percutaneous coronary interventions may be reported with this code as appropriate | Codes the diagnostic and interventional imaging portion of the procedure during which J0130 is given.

    96365 | Intravenous infusion, therapeutic, prophylactic, or diagnostic; initial, up to 1 hour | When an infusion of adjunctive antiplatelet medication is started in conjunction with bolus administration; may be used if infusion services are billed separately (verify payer policy).

    Related Modifiers

    8 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    174400000X
    2084P0800X
    207RC0000X
    363L00000X
    103T00000X
    343900000X
    2471C3402X
    246ZC0007X

    Related ICD-10-CM Codes

    27 rows

    ICD-10-CM CodeDescription
    I07.1Rheumatic tricuspid insufficiency
    I20.0Unstable angina
    I20.9Angina pectoris, unspecified
    I21.02ST elevation (STEMI) myocardial infarction involving left anterior descending coronary artery
    I21.3ST elevation (STEMI) myocardial infarction of unspecified site
    I21.4Non-ST elevation (NSTEMI) myocardial infarction
    I21.9Acute myocardial infarction, unspecified
    I21.A1Myocardial infarction type 2
    I22.1Subsequent ST elevation (STEMI) myocardial infarction of inferior wall
    I22.9Subsequent ST elevation (STEMI) myocardial infarction of unspecified site

    Showing 1–10 of 27

    Related Payer Policy Updates

    Specialty: Hematology/Oncology1 / 3

    10 rows

    PolicyPayerEffective Date
    Hematology - AdzynmaCigna2026-10-15
    Tumor Treating Fields for Pancreatic Cancerselect_health2026-10-01
    Axicabtagene ciloleucel (Yescarta®) coverageBaylor Scott & White Health Plan2026-10-01
    Electric Tumor Treatment Field Therapy (for Kentucky Only)UnitedHealthcare2026-10-01
    Electric Tumor Treatment Field Therapy (for Kansas Only)UnitedHealthcare2026-10-01
    Electric Tumor Treatment Field Therapy (for Idaho Only)UnitedHealthcare2026-10-01
    Brexucabtagene autoleucel (Tecartus) CoverageBaylor Scott & White Health Plan2026-10-01
    Electric Tumor Treatment Field Therapy (for Pennsylvania Only)UnitedHealthcare2026-10-01
    Epithelial Cell Cytology in Breast Cancer Risk AssessmentOscar Health2026-10-01
    Factor VIII ProductsCigna2026-09-15

    Related Codes

    HCPCS-J0013-ESKETAMINE-NASAL-SPRAY-1MG

    HCPCS Level II J0013: Esketamine Nasal Spray, 1 mg

    HCPCS-J0120-INJECTION-TETRACYCLINE-250MG

    HCPCS Level II J0120: Injection, Tetracycline, up to 250 mg

    HCPCS-J0121-OMADACYCLINE-INJECTION-1MG

    HCPCS Level II J0121: Omadacycline Injection, 1 mg

    HCPCS-J0122-ERAVACYCLINE-INJECTION-1MG

    HCPCS Level II J0122: Injection, eravacycline, 1 mg

    HCPCS-J0129-ABATACEPT-INJECTION-10MG-PHYSICIAN-SUPERVISED

    HCPCS Level II J0129: Abatacept Injection, 10 mg

    HCPCS-J0131-INJECTION-ACETAMINOPHEN-10MG-PARENTERAL-ANALGESIC

    HCPCS Level II J0131: Injection, Acetaminophen 10 mg

    HCPCS-J0132-INJECTION-ACETYLCYSTEINE-100MG-INJECTABLE-MEDICATION

    HCPCS Level II J0132: Injection, Acetylcysteine 100 mg

    HCPCS-J0133-ACYCLOVIR-INJECTION-5MG

    HCPCS Level II J0133: Injection, Acyclovir 5 mg

    HCPCS-J0134-ACETAMINOPHEN-INJECTION-FRESENIUS-KABI-10MG

    HCPCS Level II J0134: Injection, Acetaminophen (10 mg)

    HCPCS-J0135-ADALIMUMAB-20MG-INJECTION

    HCPCS Level II J0135: Injection, adalimumab, 20 mg

    Showing 1–10 of 991

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    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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    36415 | Collection of venous blood by venipuncture | Routine laboratory monitoring (e.g., hemoglobin, platelet counts) before and after administration of J0130 as part of clinical management.