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    v1.0.28
    OpenPayerBilling CodesOther disorders of blood and blood-forming organsICD-10-CM d75-other-and-unspecified-blood-disorders
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    ICD-10-CM Code For Other And Unspecified Diseases Of Blood And Blood-Forming Organs: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group D75 includes disorders of blood and blood-forming organs that are not classified elsewhere, such as certain eosinophil disorders and other specified or unspecified white blood cell abnormalities. These ICD-10-CM diagnosis codes are used to document hematologic conditions with abnormal blood cell counts or function, capturing disease severity, organ involvement, or clinical complexity relevant to this group. Accurate coding within the ICD-10-CM D75 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM D75: Other And Unspecified Diseases Of Blood And Blood-Forming Organs Overview

    This group includes disorders of the blood and blood-forming organs that are not classified elsewhere, such as certain eosinophilia, other specified disorders of white blood cells, and unspecified blood disorders. These conditions affect hematologic function and may impact multiple organ systems through abnormal blood cell counts or function. Accurate coding is important for proper reimbursement and to reflect clinical complexity in claims and medical records.

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    When to Use

    Use a code from this group when a patient has a documented hematologic disorder that fits the descriptors in this category and no more specific ICD-10-CM code applies. These codes are appropriate when clinical documentation specifies other or unspecified blood disorders affecting cell counts or function without classification elsewhere.

    ICD-10-CM Codes

    13 rows

    ICD-10-CM CodeDescription
    D75.0Familial erythrocytosis
    D75.1Secondary polycythemia
    D75.81Myelofibrosis
    D75.821Non-immune heparin-induced thrombocytopenia
    D75.822Immune-mediated heparin-induced thrombocytopenia
    D75.828Other heparin-induced thrombocytopenia syndrome
    D75.829Heparin-induced thrombocytopenia, unspecified
    D75.838Other thrombocytosis
    D75.839Thrombocytosis, unspecified
    D75.84Other platelet-activating anti-PF4 disorders
    D75.89Other specified diseases of blood and blood-forming organs
    D75.9Disease of blood and blood-forming organs, unspecified
    D75.AGlucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia

    DRG Codes

    15 rows

    DRG CodeDescription
    791Prematurity with Major Problems
    793Full Term Neonate with Major Problems
    813Coagulation Disorders
    814Reticuloendothelial and Immunity Disorders with MCC
    815Reticuloendothelial and Immunity Disorders with CC
    816Reticuloendothelial and Immunity Disorders without CC/MCC
    820Lymphoma and Leukemia with Major O.R. Procedures with MCC
    821Lymphoma and Leukemia with Major O.R. Procedures with CC
    822Lymphoma and Leukemia with Major O.R. Procedures without CC/MCC
    823Lymphoma and Non-Acute Leukemia with Other Procedures with MCC
    824Lymphoma and Non-Acute Leukemia with Other Procedures with CC
    825Lymphoma and Non-Acute Leukemia with Other Procedures without CC/MCC
    840Lymphoma and Non-Acute Leukemia with MCC
    841Lymphoma and Non-Acute Leukemia with CC
    842Lymphoma and Non-Acute Leukemia without CC/MCC

    Typical Clinical Scenarios

    • An adult presents to the emergency department with acute onset high fevers, rigors, and marked leukocytosis after recently starting a new antibiotic; peripheral smear and flow cytometry show marked neutrophil proliferation consistent with a leukemoid reaction rather than leukemia, and the clinician documents a disorder of white blood cell proliferation. Typical codes: D75.1.
    • A middle-aged patient with long-standing mild macrocytic anemia is followed in hematology clinic for persistent splenomegaly and intermittent thrombocytopenia; bone marrow biopsy demonstrates extramedullary hematopoiesis and a chronic nonmalignant disorder of blood-cell formation is recorded as the primary diagnosis. Typical codes: D75.81, D75.82.
    • A hospitalized patient with advanced solid-organ malignancy develops symptomatic anemia and is found to have transfusion-dependent erythrocytopenia attributed to a secondary bone marrow failure process; the blood disorder is coded as an unspecified or other disorder of blood-forming organs when a specific etiology is not established. Typical codes: D75.9, D75.89.

    Related Codes

    D70-NEUTROPENIA

    ICD-10-CM Code For Neutropenia: Group Overview

    D71-FUNCTIONAL-DISORDERS-OF-POLYMORPHONUCLEAR-NEUTROPHILS

    ICD-10-CM Code For Functional Disorders Of Polymorphonuclear Neutrophils: Group Overview

    D72-OTHER-DISORDERS-OF-WHITE-BLOOD-CELLS

    ICD-10-CM Code For Other Disorders Of White Blood Cells: Group Overview

    D73-DISEASES-OF-SPLEEN

    ICD-10-CM Code For Diseases Of Spleen: Group Overview

    D74-METHEMOGLOBINEMIA

    ICD-10-CM Code For Methemoglobinemia: Group Overview

    D76-OTHER-SPECIFIED-LYMPHORETICULAR-DISEASES

    ICD-10-CM Code For Other Specified Diseases With Participation Of Lymphoreticular And Reticulohistiocytic Tissue: Group Overview

    D77-OTHER-DISORDERS-OF-BLOOD

    ICD-10-CM Code For Other Disorders Of Blood And Blood-Forming Organs In Diseases Classified Elsewhere: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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