Loading...

    Explore
    • Policy Monitoring
    • Live Policy Feed
    • Billing Codes
    • NPI Medicare & Medicaid
    • Healthcare Providers
    • Health Insurance Payers
    • States
    • Service Lines
    • Taxonomy Codes
    Lookup tools
    • Billing Code Lookup
    • CPT Modifier Lookup
    • Provider Taxonomy Code Lookup
    • Healthcare Provider & Facility Lookup
    • Health Insurance Payer Lookup
    • Payer Contact Directory

    Policy & Benchmark Tools

    • Prior Authorization Lookup
    • Coverage Criteria Lookup
    • Timely Filing Lookup
    • Billing Code Reimbursement Rates
    • Payer Comparison Dashboard
    • Facility Comparison Dashboard
    • All tools

    Company

    • About OpenPayer
    • Data Sources
    • Trek Health
    OpenPayerby Trek Health
    LinkedInYouTube

    © 2026 Trek Health. All rights reserved.

    OpenPayer is built and maintained by Trek Health.

    v1.0.28
    OpenPayerBilling CodesOther disorders of blood and blood-forming organsICD-10-CM d76-other-specified-lymphoreticular-diseases
    Ask Trek AI about this page

    ICD-10-CM Code For Other Specified Diseases With Participation Of Lymphoreticular And Reticulohistiocytic Tissue: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group D76 includes specified disorders involving lymphoreticular and reticulohistiocytic tissue such as histiocytoses and related proliferative conditions that can affect lymph nodes, skin, spleen, and other organs. These ICD-10-CM diagnosis codes are used to document clinical scenarios including localized or systemic histiocytic proliferations, disease severity, organ involvement, and diagnostic complexity relevant to this group. Accurate coding within the ICD-10-CM D76 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

    Customize your policy alerts

    Sign up for ICD-10-CM Code For Other Specified Diseases With Participation Of Lymphoreticular And Reticulohistiocytic Tissue: Group Overview policy alerts

    Get alerted when relevant policies change without checking for updates manually.

    Monitor payer policy activity

    Receive email alerts as soon as relevant payer policies are published or updated.

    ICD-10-CM D76: Other Specified Diseases With Participation Of Lymphoreticular And Reticulohistiocytic Tissue Overview

    This group includes uncommon disorders characterized by involvement of lymphoreticular and reticulohistiocytic tissues, such as certain histiocytic proliferations and reticulohistiocytosis. These conditions affect the immune and hematologic systems and may involve lymph nodes, spleen, skin, or other organs. Accurate coding matters for reimbursement because it ensures correct clinical documentation and supports appropriate claim processing.

    Table of contents

    Progress1 / 6

    Explore openpayer tools

    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
    • Taxonomy CodesNUCC specialty codes
    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
    • Timely FilingFiling deadlines by payer
    • Coverage CriteriaMedical necessity by payer
    • Payer ContactsClaims, PA & appeals contacts
    View all tools

    When to Use

    Use codes from this group when clinical documentation indicates a specified histiocytic or reticulohistiocytic disorder involving lymphoreticular tissues or related organ involvement. Assign the most specific code that reflects the documented disease presentation, organ involvement, and any associated manifestations.

    ICD-10-CM Codes

    3 rows

    ICD-10-CM CodeDescription
    D76.1Hemophagocytic lymphohistiocytosis
    D76.2Hemophagocytic syndrome, infection-associated
    D76.3Other histiocytosis syndromes

    DRG Codes

    3 rows

    DRG CodeDescription
    814Reticuloendothelial and Immunity Disorders with MCC
    815Reticuloendothelial and Immunity Disorders with CC
    816Reticuloendothelial and Immunity Disorders without CC/MCC

    Typical Clinical Scenarios

    • An adult patient presents to the emergency department with several days of high fevers, progressive fatigue, and new-onset painless cervical and axillary lymphadenopathy after a recent viral illness. Laboratory studies reveal marked hyperferritinemia, elevated liver enzymes, cytopenias, and bone marrow biopsy shows hemophagocytosis consistent with a reactive histiocytic proliferation; a diagnosis from this group is assigned to capture a systemic histiocytic disorder associated with lymphoreticular tissue involvement. Typical codes: D76.1
    • A child is evaluated in outpatient hematology for persistent lymphadenopathy, intermittent low-grade fevers, and weight loss over months; excisional lymph node biopsy demonstrates non-Langerhans cell histiocytosis with granulomatous inflammation localized to lymphoreticular tissue without systemic organ failure. A code from this group is used to document a chronic, localized histiocytic disorder affecting lymphoid structures managed longitudinally. Typical codes: D76.2
    • A hospitalized patient with known autoimmune disease develops sudden multi-organ dysfunction with fever and pancytopenia; bone marrow examination identifies widespread histiocytic proliferation with reticulohistiocytic infiltration contributing to the clinical decompensation. A code from this group is assigned as a secondary diagnosis to denote the histiocytic disorder complicating the primary illness and driving the acute presentation. Typical codes: D76.3

    Related Codes

    D70-NEUTROPENIA

    ICD-10-CM Code For Neutropenia: Group Overview

    D71-FUNCTIONAL-DISORDERS-OF-POLYMORPHONUCLEAR-NEUTROPHILS

    ICD-10-CM Code For Functional Disorders Of Polymorphonuclear Neutrophils: Group Overview

    D72-OTHER-DISORDERS-OF-WHITE-BLOOD-CELLS

    ICD-10-CM Code For Other Disorders Of White Blood Cells: Group Overview

    D73-DISEASES-OF-SPLEEN

    ICD-10-CM Code For Diseases Of Spleen: Group Overview

    D74-METHEMOGLOBINEMIA

    ICD-10-CM Code For Methemoglobinemia: Group Overview

    D75-OTHER-AND-UNSPECIFIED-BLOOD-DISORDERS

    ICD-10-CM Code For Other And Unspecified Diseases Of Blood And Blood-Forming Organs: Group Overview

    D77-OTHER-DISORDERS-OF-BLOOD

    ICD-10-CM Code For Other Disorders Of Blood And Blood-Forming Organs In Diseases Classified Elsewhere: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
    Published by

    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.