ICD-10-CM Code For Other Disorders Of White Blood Cells: Group Overview

The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group D72 includes disorders of white blood cells such as leukopenia, leukocytosis, neutropenia, and other specified or unspecified white blood cell abnormalities that affect immune function and hematopoiesis. These ICD-10-CM diagnosis codes are used to document clinical scenarios including abnormal white blood cell counts, immune compromise, or bone marrow dysfunction, capturing disease severity and associated complications. Accurate coding within the ICD-10-CM D72 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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ICD-10-CM D72: Other Disorders Of White Blood Cells Overview

This group represents a range of conditions affecting white blood cells, including quantitative and qualitative abnormalities that do not fit into other specific categories. These disorders target the hematologic and immune systems and can impact infection risk, inflammation, and marrow function. Accurate coding matters for proper claim processing and reflects clinical severity for reimbursement and care coordination.

When to Use

Use a code from this group when a patient has documented abnormal white blood cell counts or clinically significant white blood cell dysfunction that is not classified elsewhere. These codes apply when laboratory results, clinical findings, or clinician documentation identify a specific or unspecified white blood cell disorder.

ICD-10-CM Codes

22 rows

ICD-10-CM Code	Description
D72.0	Genetic anomalies of leukocytes
D72.10	Eosinophilia, unspecified
D72.110	Idiopathic hypereosinophilic syndrome [IHES]
D72.111	Lymphocytic Variant Hypereosinophilic Syndrome [LHES]
D72.118	Other hypereosinophilic syndrome
D72.119	Hypereosinophilic syndrome [HES], unspecified
D72.12	Drug rash with eosinophilia and systemic symptoms syndrome
D72.18	Eosinophilia in diseases classified elsewhere
D72.19	Other eosinophilia
D72.810	Lymphocytopenia
D72.818	Other decreased white blood cell count
D72.819	Decreased white blood cell count, unspecified
D72.820	Lymphocytosis (symptomatic)
D72.821	Monocytosis (symptomatic)
D72.822	Plasmacytosis
D72.823	Leukemoid reaction
D72.824	Basophilia
D72.825	Bandemia
D72.828	Other elevated white blood cell count
D72.829	Elevated white blood cell count, unspecified

Showing 1–20 of 22

DRG Codes

6 rows

DRG Code	Description
808	Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with MCC
809	Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with CC
810	Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCC
814	Reticuloendothelial and Immunity Disorders with MCC
815	Reticuloendothelial and Immunity Disorders with CC
816	Reticuloendothelial and Immunity Disorders without CC/MCC

Typical Clinical Scenarios

An adult presents to the emergency department with acute onset fever, malaise, and markedly elevated white blood cell count on urgent CBC with differential; peripheral smear and flow cytometry exclude leukemia but show significant neutrophilia and a reactive left shift associated with severe bacterial sepsis. A diagnosis from this group is assigned to document an acute disorder of white blood cells secondary to infection when no malignant etiology is identified. Typical codes: D72.0, D72.19
A middle-aged patient is seen in outpatient hematology for chronic neutropenia discovered during routine testing and recurrent oral ulcers and cellulitis over the past year; workup excludes congenital causes and bone marrow biopsy is nondiagnostic, indicating an idiopathic or chronic noncyclic neutropenia. A code from this group is used to capture the chronic disorder of white blood cells as the primary hematologic diagnosis for ongoing management and follow-up. Typical codes: D72.10, D72.11
A hospitalized elderly patient receiving chemotherapy develops new severe neutropenia with febrile episodes and documented bacterial infection requiring isolation and granulocyte colony-stimulating factor support; the neutropenia is a complication of treatment and increases morbidity during the admission. A diagnosis from this group is assigned to reflect the treatment-related white blood cell disorder complicating the cancer care. Typical codes: D72.82, D72.829}

Related Codes

D70-NEUTROPENIA

ICD-10-CM Code For Neutropenia: Group Overview

D71-FUNCTIONAL-DISORDERS-OF-POLYMORPHONUCLEAR-NEUTROPHILS

ICD-10-CM Code For Functional Disorders Of Polymorphonuclear Neutrophils: Group Overview

D73-DISEASES-OF-SPLEEN

ICD-10-CM Code For Diseases Of Spleen: Group Overview

D74-METHEMOGLOBINEMIA

ICD-10-CM Code For Methemoglobinemia: Group Overview

D75-OTHER-AND-UNSPECIFIED-BLOOD-DISORDERS

ICD-10-CM Code For Other And Unspecified Diseases Of Blood And Blood-Forming Organs: Group Overview

D76-OTHER-SPECIFIED-LYMPHORETICULAR-DISEASES

ICD-10-CM Code For Other Specified Diseases With Participation Of Lymphoreticular And Reticulohistiocytic Tissue: Group Overview

D77-OTHER-DISORDERS-OF-BLOOD

ICD-10-CM Code For Other Disorders Of Blood And Blood-Forming Organs In Diseases Classified Elsewhere: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

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When to Use

ICD-10-CM Codes

22 rows

ICD-10-CM Code	Description
D72.0	Genetic anomalies of leukocytes
D72.10	Eosinophilia, unspecified
D72.110	Idiopathic hypereosinophilic syndrome [IHES]
D72.111	Lymphocytic Variant Hypereosinophilic Syndrome [LHES]
D72.118	Other hypereosinophilic syndrome
D72.119	Hypereosinophilic syndrome [HES], unspecified
D72.12	Drug rash with eosinophilia and systemic symptoms syndrome
D72.18	Eosinophilia in diseases classified elsewhere
D72.19	Other eosinophilia
D72.810	Lymphocytopenia
D72.818	Other decreased white blood cell count
D72.819	Decreased white blood cell count, unspecified
D72.820	Lymphocytosis (symptomatic)
D72.821	Monocytosis (symptomatic)
D72.822	Plasmacytosis
D72.823	Leukemoid reaction
D72.824	Basophilia
D72.825	Bandemia
D72.828	Other elevated white blood cell count
D72.829	Elevated white blood cell count, unspecified

Showing 1–20 of 22

DRG Codes

6 rows

DRG Code	Description
808	Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with MCC
809	Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with CC
810	Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCC
814	Reticuloendothelial and Immunity Disorders with MCC
815	Reticuloendothelial and Immunity Disorders with CC
816	Reticuloendothelial and Immunity Disorders without CC/MCC

Typical Clinical Scenarios

An adult presents to the emergency department with acute onset fever, malaise, and markedly elevated white blood cell count on urgent CBC with differential; peripheral smear and flow cytometry exclude leukemia but show significant neutrophilia and a reactive left shift associated with severe bacterial sepsis. A diagnosis from this group is assigned to document an acute disorder of white blood cells secondary to infection when no malignant etiology is identified. Typical codes: D72.0, D72.19
A middle-aged patient is seen in outpatient hematology for chronic neutropenia discovered during routine testing and recurrent oral ulcers and cellulitis over the past year; workup excludes congenital causes and bone marrow biopsy is nondiagnostic, indicating an idiopathic or chronic noncyclic neutropenia. A code from this group is used to capture the chronic disorder of white blood cells as the primary hematologic diagnosis for ongoing management and follow-up. Typical codes: D72.10, D72.11
A hospitalized elderly patient receiving chemotherapy develops new severe neutropenia with febrile episodes and documented bacterial infection requiring isolation and granulocyte colony-stimulating factor support; the neutropenia is a complication of treatment and increases morbidity during the admission. A diagnosis from this group is assigned to reflect the treatment-related white blood cell disorder complicating the cancer care. Typical codes: D72.82, D72.829}

Related Codes

D70-NEUTROPENIA

ICD-10-CM Code For Neutropenia: Group Overview

D71-FUNCTIONAL-DISORDERS-OF-POLYMORPHONUCLEAR-NEUTROPHILS

ICD-10-CM Code For Functional Disorders Of Polymorphonuclear Neutrophils: Group Overview

D73-DISEASES-OF-SPLEEN

ICD-10-CM Code For Diseases Of Spleen: Group Overview

D74-METHEMOGLOBINEMIA

ICD-10-CM Code For Methemoglobinemia: Group Overview

D75-OTHER-AND-UNSPECIFIED-BLOOD-DISORDERS

ICD-10-CM Code For Other And Unspecified Diseases Of Blood And Blood-Forming Organs: Group Overview

D76-OTHER-SPECIFIED-LYMPHORETICULAR-DISEASES

ICD-10-CM Code For Other Specified Diseases With Participation Of Lymphoreticular And Reticulohistiocytic Tissue: Group Overview

D77-OTHER-DISORDERS-OF-BLOOD

ICD-10-CM Code For Other Disorders Of Blood And Blood-Forming Organs In Diseases Classified Elsewhere: Group Overview

Frequently Asked Questions

References

1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.

Published by

Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

ICD-10-CM Code For Other Disorders Of White Blood Cells: Group Overview

Sign up for ICD-10-CM Code For Other Disorders Of White Blood Cells: Group Overview policy alerts

ICD-10-CM D72: Other Disorders Of White Blood Cells Overview

ICD-10-CM Code For Other Disorders Of White Blood Cells: Group Overview

Sign up for ICD-10-CM Code For Other Disorders Of White Blood Cells: Group Overview policy alerts

ICD-10-CM D72: Other Disorders Of White Blood Cells Overview

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-CM codes are included in the D72 group for disorders of white blood cells?

How does accurate coding within the `D72` group affect reimbursement?

Which DRGs may be related to diagnoses coded in the `D72` group?

What clinical scenarios are captured by ICD-10-CM codes in the `D72` group?

When should a coder choose an unspecified `D72` code versus a more specific code?

References

When to Use

ICD-10-CM Codes

DRG Codes

Typical Clinical Scenarios

Related Codes

Which ICD-10-CM codes are included in the D72 group for disorders of white blood cells?

How does accurate coding within the `D72` group affect reimbursement?

Which DRGs may be related to diagnoses coded in the `D72` group?

What clinical scenarios are captured by ICD-10-CM codes in the `D72` group?

When should a coder choose an unspecified `D72` code versus a more specific code?

References