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    OpenPayerBilling CodesOther disorders of blood and blood-forming organsICD-10-CM d71-functional-disorders-of-polymorphonuclear-neutrophils
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    ICD-10-CM Code For Functional Disorders Of Polymorphonuclear Neutrophils: Group Overview

    The International Classification of Diseases, Tenth Revision, Clinical Modification (ICD-10-CM) code group D71 includes functional disorders of polymorphonuclear neutrophils, encompassing inherited or acquired defects in neutrophil function that predispose to recurrent infections and inflammatory complications. These ICD-10-CM diagnosis codes are used to document clinical scenarios involving impaired neutrophil chemotaxis, phagocytosis, oxidative burst, or other functional abnormalities, capturing disease severity, infection history, and immune system involvement. Accurate coding within the ICD-10-CM D71 group supports proper claim adjudication, complete clinical documentation, and appropriate reimbursement.

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    ICD-10-CM D71: Functional Disorders Of Polymorphonuclear Neutrophils Overview

    This group includes diagnoses describing functional defects of polymorphonuclear neutrophils, a key component of innate immunity that affects infection defense and inflammatory responses. These conditions target the hematologic and immune systems and can present with recurrent or severe infections, impaired wound healing, or unusual inflammatory findings. Accurate coding matters for clinical communication and for correct reimbursement determination because it documents disease severity and underlying immune dysfunction.

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    When to Use

    Use a code from this group when documentation specifies a functional neutrophil disorder or a named condition involving neutrophil dysfunction. Assign these codes to reflect the documented clinical findings, severity, and any related infectious complications.

    ICD-10-CM Codes

    3 rows

    ICD-10-CM CodeDescription
    D71.1Leukocyte adhesion deficiency
    D71.8Other functional disorders of polymorphonuclear neutrophils
    D71.9Functional disorders of polymorphonuclear neutrophils, unspecified

    DRG Codes

    3 rows

    DRG CodeDescription
    808Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with MCC
    809Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders with CC
    810Major Hematological and Immunological Diagnoses Except Sickle Cell Crisis and Coagulation Disorders without CC/MCC

    Typical Clinical Scenarios

    • A previously healthy young adult presents to the emergency department with high fever, severe oral mucositis, and rapidly progressive painful skin pustules after starting chemotherapy a week earlier; laboratory testing reveals profound neutrophil dysfunction with recurrent bacterial infections despite normal neutrophil counts, prompting urgent immunology and hematology evaluation. A diagnosis from this group is assigned to capture a functional defect of neutrophils causing acute infectious susceptibility after an inciting therapy. Typical codes: D71.1.
    • A pediatric patient with a lifelong history of recurrent skin abscesses, delayed separation of the umbilical cord in infancy, and chronic lymphadenitis is seen in specialty clinic for evaluation of an inherited neutrophil disorder; genetic testing confirms a congenital neutrophil functional defect and the child is followed longitudinally for infection prevention and monitoring. A code from this group is used to document the chronic congenital neutrophil functional disorder as the underlying cause of recurrent infections. Typical codes: D71.8, D71.9.
    • An adult with diabetes is hospitalized for a severe foot ulcer complicated by persistent purulent infection that fails to respond to appropriate antibiotics and debridement; workup identifies impaired neutrophil oxidative burst leading to poor microbial killing and infection control, and the neutrophil dysfunction is recorded as a comorbidity affecting wound healing and treatment planning. Typical codes: D71.8.

    Related Codes

    D70-NEUTROPENIA

    ICD-10-CM Code For Neutropenia: Group Overview

    D72-OTHER-DISORDERS-OF-WHITE-BLOOD-CELLS

    ICD-10-CM Code For Other Disorders Of White Blood Cells: Group Overview

    D73-DISEASES-OF-SPLEEN

    ICD-10-CM Code For Diseases Of Spleen: Group Overview

    D74-METHEMOGLOBINEMIA

    ICD-10-CM Code For Methemoglobinemia: Group Overview

    D75-OTHER-AND-UNSPECIFIED-BLOOD-DISORDERS

    ICD-10-CM Code For Other And Unspecified Diseases Of Blood And Blood-Forming Organs: Group Overview

    D76-OTHER-SPECIFIED-LYMPHORETICULAR-DISEASES

    ICD-10-CM Code For Other Specified Diseases With Participation Of Lymphoreticular And Reticulohistiocytic Tissue: Group Overview

    D77-OTHER-DISORDERS-OF-BLOOD

    ICD-10-CM Code For Other Disorders Of Blood And Blood-Forming Organs In Diseases Classified Elsewhere: Group Overview

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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