CPT code 80402 denotes an ACTH stimulation test, a diagnostic endocrine procedure that assesses adrenal gland function by measuring cortisol response to synthetic adrenocorticotropic hormone. Nationally, this test is an important tool for diagnosing primary and secondary adrenal insufficiency and for guiding endocrine management across outpatient and hospital settings. It carries clinical significance for endocrinologists, primary care clinicians, and inpatient teams evaluating suspected adrenal disorders.

Key payers covered in this analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of the clinical context for CPT code 80402, typical sites of service, and the service type. The publication also outlines payer coverage considerations, common billing modifiers associated with laboratory and diagnostic services where available, and links to related procedural coding where applicable. Practical information includes benchmarks and billing practice highlights relevant to clinicians, coding professionals, and revenue cycle teams.

This summary is intended for a national audience. It provides a clear clinical and billing framing for CPT code 80402 so stakeholders can align documentation, ordering, and billing practices with the clinical purpose of the ACTH stimulation test.