CPT code 78104 is a national billing code for a whole-body skeletal scintigraphy performed after intravenous injection of a radiopharmaceutical. The study captures serial images of the entire skeleton to assess tracer uptake, commonly used to detect metastatic disease, occult fractures, infection, and other metabolic bone disorders. As a standardized diagnostic nuclear medicine procedure, CPT code 78104 supports clinical decision-making across inpatient and outpatient imaging settings and influences utilization and coverage policies for advanced imaging.

Key payers in the analysis include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Readers will find a concise overview of what CPT code 78104 represents, typical sites of service, and the clinical contexts in which whole-body bone scans are applied. The publication also summarizes common billing considerations, reimbursement benchmarks where available, and policy developments that affect nationwide coverage for nuclear medicine skeletal imaging.

This resource is designed for coding professionals, radiology administrators, and policy analysts seeking a clear, national-level reference on CPT code 78104, including operational implications for imaging departments and payers.