CPT code 48154 represents a major pancreatic and duodenal resection with biliary and enteric reconstruction. It is used for a complex abdominal operation that removes part of the pancreas and nearly the entire duodenum, with reestablishment of bile and intestinal continuity. This code captures high-acuity surgical care with significant implications for perioperative resource use, length of stay, and post‑operative follow-up.

Key national payers examined include Aetna, Blue Cross Blue Shield, Cigna Health, UnitedHealthcare, and Medicare. Coverage and payment policies for this type of complex resection affect hospital reimbursement, surgical practice patterns, and patient access to specialized centers.

Readers will find context on the clinical nature of the procedure, typical site-of-service expectations, and the policy and billing considerations that commonly accompany complex pancreaticoduodenal resections. The publication summarizes benchmarks where available, discusses payer policy themes and prior authorization patterns, and outlines clinical coding context relevant to claims processing. Data not available in the input is noted explicitly where applicable.