Loading...

    Explore
    • Policy Monitoring
    • Live Policy Feed
    • Billing Codes
    • Healthcare Providers
    • Health Insurance Payers
    • States
    • Service Lines
    • Taxonomy Codes
    Lookup tools
    • Billing Code Lookup
    • CPT Modifier Lookup
    • Provider Taxonomy Code Lookup
    • Healthcare Provider & Facility Lookup
    • Health Insurance Payer Lookup
    • Payer Contact Directory

    Policy & Benchmark Tools

    • Prior Authorization Lookup
    • Coverage Criteria Lookup
    • Timely Filing Lookup
    • Billing Code Reimbursement Rates
    • Payer Comparison Dashboard
    • Facility Comparison Dashboard
    • All tools

    Company

    • About OpenPayer
    • Data Sources
    • Trek Health
    OpenPayerby Trek Health
    LinkedInYouTube

    © 2026 Trek Health. All rights reserved.

    OpenPayer is built and maintained by Trek Health.

    v1.0.30
    OpenPayerBilling CodesExcision Procedures on the PancreasCPT cpt-48146-near-total-pancreatectomy
    Ask Trek AI about this page

    CPT 48146: Near Total Pancreatectomy

    Medicare pays $1781 on average nationally for this procedure.

    CPT code 48146 describes a near total pancreatectomy, a major abdominal surgical procedure in which the surgeon removes most of the pancreas; this is an open or laparoscopic pancreatic resection performed primarily for extensive pancreatic disease such as diffuse neoplasm or severe chronic pancreatitis. The service type is major abdominal surgery, and the typical site of service is an inpatient hospital operating room with postoperative inpatient care. Data not available in the input.

    For related coverage guidance, see recent payer policy updates: Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disorders, Esophagogastroduodenoscopy (EGD) Coverage Policy, Radiofrequency Therapy for Fecal Incontinence.

    Customize your policy alerts

    Sign up for cpt 48146 policy alerts

    Get alerted when payer policies referencing 48146 are released or updated.

    Monitor payer policy activity

    Receive email alerts as soon as relevant payer policies are published or updated.

    Table of contents

    Progress1 / 6

    Explore openpayer tools

    • Billing CodesCPT, HCPCS, DRG & more
    • Reimbursement RatesCommercial vs. Medicare rate reports
    • Facility ComparisonBeds, revenue & payer mix
    • ProvidersHospitals & facilities
    • PayersPlans & market footprint
    • Taxonomy CodesNUCC specialty codes
    • ModifiersCPT modifiers & usage
    • Prior AuthorizationPA policies by payer & drug
    • Timely FilingFiling deadlines by payer
    • Coverage CriteriaMedical necessity by payer
    • Payer ContactsClaims, PA & appeals contacts
    View all tools

    Clinical & Coding Specifications

    Clinical Context

    A 52-year-old patient with a history of multifocal, non-resectable pancreatic neuroendocrine tumor presents with progressive endocrine dysfunction and refractory abdominal pain. After multidisciplinary tumor board review and failed attempts at organ-preserving therapy, the surgical team schedules a near total pancreatectomy to remove the majority of the pancreas while preserving minimal pancreatic tissue to maintain some endocrine/exocrine function.

    Preoperative workflow includes cross-sectional imaging (CT or MRI), endocrine and nutritional assessment, optimization of glycemic control, informed consent covering risks (bleeding, infection, pancreatic fistula, brittle diabetes), and coordination with anesthesia and blood bank for potential transfusion. Intraoperative workflow involves laparotomy or minimally invasive access, dissection of pancreatic tissue, vascular control, possible splenectomy depending on oncologic margins and vascular involvement, reconstruction as indicated, placement of drains, and hemostasis. Postoperative management focuses on intensive monitoring, pain control, glycemic management (insulin therapy), enzyme supplementation, infection surveillance, and discharge planning with endocrine and nutrition follow-up.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    48146Near total pancreatectomy (primary code)Primary operative code describing removal of most of the pancreas
    38100Splenectomy, total, without autotransplantationOften performed concurrently if splenic vessels or oncologic margins require removal of the spleen during a near total pancreatectomy
    44005Enterolysis (lysis of peritoneal adhesions)Performed when dense adhesions are encountered intraoperatively and require lysis to gain access to the pancreas
    34830Reconstruction of portal vein (interposition graft)Performed when tumor invades portal or mesenteric veins requiring vascular resection and reconstruction during pancreatectomy
    49406Insertion of intra-abdominal drainage device (percutaneous)Used for management of postoperative pancreatic fluid collections or for placement of drains intraoperatively if required
    99291Critical care, evaluation and management of the critically ill or critically injured patient, first 30–74 minutesMay be reported for immediate postoperative critical care management in the ICU following a complex near total pancreatectomy

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    23Modifier -23 (Unusual Anesthesia) is used on anesthesia service CPT codes when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia…- Use modifier -23 only on anesthesia CPT codes (00100–01999) when a procedure that normally requires no anesthesia or only local anesthesia must be performed under general anesthesia because of…
    26Modifier 26 (Professional Component) identifies and bills only the professional portion of a split service — the physician’s interpretation, report, and medical judgment — when the technical…- Use CPT Modifier -26 when you are billing only the professional component (PC) of a split‑bill eligible service—i.e., you performed the physician interpretation, medical judgment and prepared a…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    54Modifier ‑54 (“Surgical care only”) is appended to a CPT surgical procedure when the reporting surgeon performs the intraoperative (surgical) component but does not furnish the preoperative and/or…- Use modifier -54 when the reporting surgeon provided only the intraoperative (surgical) component of a procedure and preoperative and/or postoperative management has been or will be provided by…
    55Modifier –55 indicates the billing provider furnished only postoperative management for a procedure that has a global surgical period. According to AAPC, this modifier is appended to the same CPT…- Use modifier -55 when billing the same CPT surgical code that has a 10- or 90-day global period and you, as a provider other than the original surgeon, furnished ONLY postoperative management (no…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    208000000X
    207K00000X
    207L00000X
    363LF0000X
    2080S0010X
    163WC1500X
    163WA2000X
    133N00000X

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 3

    10 rows

    PolicyPayerEffective Date
    Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disordersbcbsvermont2026-12-01
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Radiofrequency Therapy for Fecal IncontinenceCigna2026-10-15
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    High-Resolution Anoscopy (HRA)Premera Bluecross2026-10-01
    Gastroesophageal and Gastrointestinal (GI) Services and ProceduresColorado Rocky Mountain Health Plans2026-10-01
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01

    Related Codes

    CPT-48100-OPEN-SURGICAL-PANCREATIC-BIOPSY-PATHOLOGY-SAMPLE

    CPT 48100: Open Biopsy of Pancreatic Lesion

    CPT-48102-PERCUTANEOUS-PANCREATIC-NEEDLE-BIOPSY-PATHOLOGY

    CPT 48102: Percutaneous Needle Biopsy of Pancreas

    CPT-48105-PANCREATIC-RESECTION-DEBRIDEMENT-ACUTE-NECROTIZING-PANCREATITIS

    CPT 48105: Pancreatic Resection and Debridement for Necrotizing Pancreatitis

    CPT-48120-PANCREATIC-LESION-EXCISION

    CPT 48120: Excision of Lesion of Pancreas

    CPT-48140-DISTAL-PANCREATECTOMY-WITHOUT-PANCREATICOJEJUNOSTOMY

    CPT 48140: Distal Pancreatectomy with or without Splenectomy

    CPT-48145-DISTAL-PANCREATECTOMY-WITH-OR-WITHOUT-SPLENECTOMY

    CPT 48145: Distal Pancreatectomy With or Without Splenectomy

    CPT-48148-AMPULLA-OF-VATER-REMOVAL-AMPULLECTOMY

    CPT 48148: Removal of the Ampulla of Vater

    CPT-48150-PANCREATICODUODENECTOMY-PYLORUS-RESECTING

    CPT 48150: Pancreaticoduodenectomy (Whipple) with Reconstruction

    CPT-48152-SUBTOTAL-PANCREATECTOMY-DUODENECTOMY-WITH-RECONSTRUCTION-NO-PANCREATICOJEJUNOSTOMY

    CPT 48152: Pancreaticoduodenectomy (Whipple) without Pancreaticojejunostomy

    CPT-48153-PANCREATICODUODENAL-RESECTION-WITH-RECONSTRUCTION

    CPT 48153: Pylorus-Preserving Pancreaticoduodenectomy

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
    Published by

    Trek Health powers OpenPayer with a leading commercial payer intelligence platform, seamlessly converting fragmented payer data into actionable insights for provider organizations.

    Trek Health ingests and normalizes Transparency in Coverage data and payer policy updates to give provider organizations a clear view of how commercial reimbursement behaves across markets, payers, and services. Our platform transforms raw payer disclosures into structured intelligence that supports contract evaluation, payer negotiations, and service line strategy. By combining market benchmarks with ongoing policy visibility, Trek helps teams identify variability, risk, and opportunity in commercial reimbursement. The result is faster insight, stronger negotiating positions, and more informed financial decisions.