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    v1.0.30
    OpenPayerBilling CodesExcision Procedures on the PancreasCPT cpt-48145-distal-pancreatectomy-with-or-without-splenectomy
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    CPT 48145: Distal Pancreatectomy With or Without Splenectomy

    Medicare pays $1532 on average nationally for this procedure.

    CPT code 48145 describes a distal pancreatectomy — surgical removal of the distal portion of the pancreas with or without concurrent splenectomy — and when performed for pancreatic duct obstruction may include creation of a jejunopancreatic anastomosis; service type: operative abdominal surgery; typical site of service: hospital operating room or inpatient surgical setting.

    For related coverage guidance, see recent payer policy updates: Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disorders, Esophagogastroduodenoscopy (EGD) Coverage Policy, Radiofrequency Therapy for Fecal Incontinence.

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    Table of contents

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    Clinical & Coding Specifications

    Clinical Context

    A typical patient is a 55–70-year-old adult presenting with symptomatic disease of the distal pancreas such as a solitary pancreatic neoplasm in the body or tail (adenocarcinoma, neuroendocrine tumor), or chronic pancreatitis with intractable pain or ductal obstruction localized to the distal gland. The workflow begins with preoperative evaluation including cross-sectional imaging (contrast CT or MRI) and endoscopic ultrasound with biopsy as indicated, staging and medical optimization, and discussion at a multidisciplinary conference when cancer is suspected. On the day of surgery the patient undergoes a distal pancreatectomy, often with concurrent splenectomy if oncologic margins or vascular anatomy require removal of the spleen. In patients with pancreatic duct obstruction where drainage is required, a pancreaticojejunostomy (anastomosis of the pancreatic remnant to the jejunum) may be performed. Intraoperative considerations include possible vascular control, proximal pancreatic transection, assessment for frozen section, and placement of surgical drains. Typical postoperative care includes pain control, monitoring for pancreatic fistula, management of drains, immunization counseling if splenectomy performed, and follow-up for adjuvant therapy if malignancy is confirmed.

    Related CPT Codes

    CPT CodeDescriptionRelationship to This Procedure
    48140Pancreatectomy, distal subtotal, with or without splenectomyAlternative code for subtotal distal resections; may be used for similar operations with different extent
    48146Pancreatectomy with resection of additional adjacent organsUse when resection extends to adjacent organs beyond standard distal pancreatectomy
    49568Drainage procedure of abdominal abscess; percutaneous, by catheter placementMay be performed preoperatively or postoperatively for infected collections or abscess related to pancreatic leak
    42700Exploratory laparotomy, exploratory celiotomy with or without biopsy(s)May be performed if diagnosis is uncertain at time of operation prior to definitive distal pancreatectomy
    44204Laparoscopy, surgical; distal pancreatectomy, includes splenectomy when performedLaparoscopic approach equivalent when minimally invasive techniques are used for distal pancreatectomy
    43280Endoscopic retrograde cholangiopancreatography (ERCP)Performed preoperatively to evaluate ductal obstruction or to place stents when indicated prior to surgery

    Related Modifiers

    12 rows

    ModifierDescriptionWhen to Use
    22Modifier –22 (Increased Procedural Services) is used when a reported procedure is substantially more extensive than normally required. The CPT Manual and CMS state it may be appended only when the…- When to use: Append modifier -22 to a procedural CPT code when the service performed is substantially more extensive than the usual service described by that code — i.e., the procedure required…
    50Modifier –50 (Bilateral Procedure) is appended to a CPT code when an identical procedure is performed on paired anatomical structures during the same operative session. The AMA states to add…- Use modifier -50 when the same CPT surgical, diagnostic, or radiology procedure is performed on paired anatomical structures (both sides of the body) during the same operative/session by the same…
    51Modifier –51 (Multiple Procedures) is used when the same provider performs multiple procedures in the same session to identify secondary, non‑exempt procedures and indicate payment reduction logic…- Use modifier -51 when the same provider performs multiple distinct procedures during the same patient encounter: report the highest‑valued procedure first (no modifier) and append -51 to…
    52Modifier ‑52 (Reduced Services) indicates that a service or procedure was partially reduced or omitted at the provider’s discretion, allowing reporting of the basic procedure number with a qualifier…- Use modifier -52 when a physician or qualified health professional electively reduces or omits part of a procedure or service (for example, performing fewer required views or omitting a portion of…
    53Modifier 53 (Discontinued Procedure) signals that a surgical or diagnostic service was begun by the physician but terminated because of extenuating circumstances that threatened the patient’s…- Use modifier -53 when a physician/qualified healthcare professional has started a surgical or diagnostic procedure (e.g., anesthesia administered, incision or scope insertion) and then discontinues…
    62Modifier 62 indicates that two surgeons function as co‑surgeons, each performing distinct parts of the same primary surgical procedure. It is appended to the primary procedure code (and any…- Use modifier -62 when two surgeons act as co‑surgeons (both primary surgeons) on a single definitive primary procedure, each performing distinct parts of the same surgical procedure (append -62 to…
    63Modifier‑63 is appended to surgical CPT codes (20000–69990) when a procedure is performed on a neonate or infant weighing ≤ 4 kg (about 8.8 lbs). The AMA/AAPC definition specifies this use and notes…- Use modifier -63 only for surgical procedures in the CPT 20000–69990 series performed on a neonate or infant who weighs ≤ 4 kg at the time of the procedure; it indicates increased complexity due to…
    66Modifier 66 (Surgical Team) is used when three or more surgeons act as primary surgeons on a single, highly complex procedure. The AMA defines it for use when a surgical team — often composed of…- Use modifier 66 when three or more surgeons act as primary surgeons working collaboratively as a surgical team on a single, highly complex or difficult procedure (for example organ…
    78CPT modifier -78 indicates an unplanned, related return to the operating or procedure room by the same provider during the global postoperative period. It is appended when treatment for a…- Use modifier -78 when an unplanned, related complication during the original procedure’s global postoperative period requires the patient to return to a formal operating or procedure room and the…
    80CPT® Modifier 80 (Assistant Surgeon) is appended to a surgical CPT code when a physician (MD or DO) provides full, continuous assistance throughout the operative procedure. It is intended only for…- Use CPT Modifier -80 when a physician (MD or DO) serves as an assistant surgeon and provides full, continuous assistance throughout the entire operative procedure; append -80 to the surgical CPT…

    Showing 1–10 of 12

    Related Provider Taxonomies

    8 rows

    Taxonomy Code
    207K00000X
    207L00000X
    207RH0000X
    2084P0800X
    273Y00000X
    2081P0301X
    2083A0100X
    167G00000X

    Related ICD-10-CM Codes

    24 rows

    ICD-10-CM CodeDescription
    C25.1Malignant neoplasm of body of pancreas
    C25.4Malignant neoplasm of endocrine pancreas
    C25.7Malignant neoplasm of other parts of pancreas
    C25.8Malignant neoplasm of overlapping sites of pancreas
    C25.9Malignant neoplasm of pancreas, unspecified
    D13.6Benign neoplasm of pancreas
    E84.9Cystic fibrosis, unspecified
    I85.01Esophageal varices with bleeding
    I85.11Secondary esophageal varices with bleeding
    K86.0Alcohol-induced chronic pancreatitis

    Showing 1–10 of 24

    Related Payer Policy Updates

    Specialty: Gastroenterology1 / 3

    10 rows

    PolicyPayerEffective Date
    Percutaneous Electrical Nerve Field Stimulation for Functional Abdominal Pain Disordersbcbsvermont2026-12-01
    Esophagogastroduodenoscopy (EGD) Coverage Policyevicore2026-11-05
    Radiofrequency Therapy for Fecal IncontinenceCigna2026-10-15
    Magnetic Sphincter Augmentation for the Treatment of Gastroesophageal Reflux Disease (GERD)univerahealthcare2026-10-15
    High-Resolution Anoscopy (HRA)Premera Bluecross2026-10-01
    Gastroesophageal and Gastrointestinal (GI) Services and ProceduresColorado Rocky Mountain Health Plans2026-10-01
    Fecal Analysis in the Diagnosis of Intestinal Dysbiosis and Fecal Microbiota Transplant TestingOscar Health2026-10-01
    Serum Testing for Hepatic Fibrosis in the Evaluation and Monitoring of Chronic Liver DiseaseOscar Health2026-10-01
    Pancreatic Enzyme Testing for Acute PancreatitisOscar Health2026-10-01
    Helicobacter pylori TestingOscar Health2026-10-01

    Related Codes

    CPT-48100-OPEN-SURGICAL-PANCREATIC-BIOPSY-PATHOLOGY-SAMPLE

    CPT 48100: Open Biopsy of Pancreatic Lesion

    CPT-48102-PERCUTANEOUS-PANCREATIC-NEEDLE-BIOPSY-PATHOLOGY

    CPT 48102: Percutaneous Needle Biopsy of Pancreas

    CPT-48105-PANCREATIC-RESECTION-DEBRIDEMENT-ACUTE-NECROTIZING-PANCREATITIS

    CPT 48105: Pancreatic Resection and Debridement for Necrotizing Pancreatitis

    CPT-48120-PANCREATIC-LESION-EXCISION

    CPT 48120: Excision of Lesion of Pancreas

    CPT-48140-DISTAL-PANCREATECTOMY-WITHOUT-PANCREATICOJEJUNOSTOMY

    CPT 48140: Distal Pancreatectomy with or without Splenectomy

    CPT-48146-NEAR-TOTAL-PANCREATECTOMY

    CPT 48146: Near Total Pancreatectomy

    CPT-48148-AMPULLA-OF-VATER-REMOVAL-AMPULLECTOMY

    CPT 48148: Removal of the Ampulla of Vater

    CPT-48150-PANCREATICODUODENECTOMY-PYLORUS-RESECTING

    CPT 48150: Pancreaticoduodenectomy (Whipple) with Reconstruction

    CPT-48152-SUBTOTAL-PANCREATECTOMY-DUODENECTOMY-WITH-RECONSTRUCTION-NO-PANCREATICOJEJUNOSTOMY

    CPT 48152: Pancreaticoduodenectomy (Whipple) without Pancreaticojejunostomy

    CPT-48153-PANCREATICODUODENAL-RESECTION-WITH-RECONSTRUCTION

    CPT 48153: Pylorus-Preserving Pancreaticoduodenectomy

    Showing 1–10 of 13

    Frequently Asked Questions

    References

    1. 1.CPT® Codes and Descriptions. AAPC. Retrieved Aug 11, 2026.Maintains the CPT code set's official descriptions and guidelines, licensed from the American Medical Association, used as the definitional source for CPT codes on this page.
    2. 2.HCPCS Quarterly Update. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's quarterly release of HCPCS Level II codes and short/long descriptors, the source for HCPCS code definitions and update history.
    3. 3.ICD-10-CM Full Code List. Centers for Medicare & Medicaid Services (CMS). Retrieved Aug 11, 2026.CMS's complete ICD-10-CM diagnosis code list, used to cross-reference diagnosis codes associated with this procedure or service.
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